Mctp1 (multiple C2 and transmembrane domain containing 1) - Rat Genome Database

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Gene: Mctp1 (multiple C2 and transmembrane domain containing 1) Rattus norvegicus
Analyze
Symbol: Mctp1
Name: multiple C2 and transmembrane domain containing 1
RGD ID: 1305199
Description: Predicted to enable calcium ion binding activity. Involved in negative regulation of cell migration; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Located in recycling endosome and synaptic vesicle membrane. Orthologous to human MCTP1 (multiple C2 and transmembrane domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diclofenac.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC309928; Mctp1-ps1; multiple C2 and transmembrane domain-containing protein 1; multiple C2 domains, transmembrane 1; multiple C2 domains, transmembrane 1, pseudogene 1; RGD1305199; similar to hypothetical protein FLJ22344
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,798,968 - 8,493,596 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl27,803,382 - 8,493,596 (+)EnsemblGRCr8
mRatBN7.226,071,408 - 6,761,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx213,149,950 - 13,873,885 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0211,249,210 - 11,973,165 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,914,158 - 6,608,224 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.023,400,883 - 4,089,949 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl23,400,977 - 4,088,989 (+)Ensemblrn6Rnor6.0
Rnor_5.023,398,033 - 4,086,933 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.423,652,722 - 4,354,754 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera22,535,961 - 3,220,251 (+)NCBICelera
RGSC_v3.123,941,173 - 4,377,606 (+)NCBI
Cytogenetic Map2q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
maneb  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-1,4-benzoquinone imine  (ISO)
nicotine  (ISO)
nitrates  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paraquat  (ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
Sunset Yellow FCF  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Multiple C2 domains transmembrane protein 1 is expressed in CNS neurons and possibly regulates cellular vesicle retrieval and oxidative stress. Qiu L, etal., J Neurochem. 2015 Nov;135(3):492-507. doi: 10.1111/jnc.13251. Epub 2015 Sep 3.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15528213   PMID:25931508  


Genomics

Comparative Map Data
Mctp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,798,968 - 8,493,596 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl27,803,382 - 8,493,596 (+)EnsemblGRCr8
mRatBN7.226,071,408 - 6,761,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx213,149,950 - 13,873,885 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0211,249,210 - 11,973,165 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,914,158 - 6,608,224 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.023,400,883 - 4,089,949 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl23,400,977 - 4,088,989 (+)Ensemblrn6Rnor6.0
Rnor_5.023,398,033 - 4,086,933 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.423,652,722 - 4,354,754 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera22,535,961 - 3,220,251 (+)NCBICelera
RGSC_v3.123,941,173 - 4,377,606 (+)NCBI
Cytogenetic Map2q11NCBI
MCTP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38594,703,690 - 95,285,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl594,703,690 - 95,285,094 (-)Ensemblhg38GRCh38
GRCh37594,039,395 - 94,620,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36594,068,957 - 94,646,035 (-)NCBIBuild 36Build 36hg18NCBI36
Celera589,904,181 - 90,498,783 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef589,215,571 - 89,810,232 (-)NCBIHuRef
CHM1_1593,474,921 - 94,052,972 (-)NCBICHM1_1
T2T-CHM13v2.0595,188,075 - 95,786,099 (-)NCBIT2T-CHM13v2.0
Mctp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391376,530,481 - 77,181,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1376,532,259 - 77,179,929 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381376,382,362 - 77,033,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1376,384,535 - 77,031,810 (+)Ensemblmm10GRCm38
MGSCv371376,522,409 - 77,171,071 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361376,850,963 - 77,495,357 (+)NCBIMGSCv36mm8
Celera1378,709,211 - 79,357,429 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.98NCBI
Mctp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541817,229,498 - 17,745,010 (+)Ensembl
ChiLan1.0NW_00495541817,229,498 - 17,746,936 (+)NCBIChiLan1.0ChiLan1.0
MCTP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2420,100,647 - 20,697,607 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1518,254,259 - 18,851,219 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0520,071,072 - 20,669,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1520,215,984 - 20,808,014 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl520,215,917 - 20,808,014 (+)EnsemblpanPan2panpan1.1
MCTP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1314,255,685 - 14,782,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl314,358,134 - 14,780,801 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha315,594,036 - 16,121,093 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0314,133,526 - 14,662,420 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl314,133,527 - 14,682,475 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1314,098,067 - 14,625,300 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0314,095,557 - 14,623,822 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0314,295,164 - 14,827,487 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mctp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,864,546 - 170,367,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365238,050,006 - 8,553,432 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365238,050,001 - 8,553,427 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCTP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2101,384,910 - 101,920,111 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12101,384,904 - 101,920,152 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22104,928,439 - 105,217,494 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCTP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1488,581,761 - 89,174,995 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl488,585,446 - 88,967,701 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604937,226,961 - 37,820,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mctp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474313,405,481 - 13,919,373 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mctp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13219,843,772 - 220,709,456 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mctp1
1778 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:51
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000017828, ENSRNOT00000064743
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat

Markers in Region
RH144441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.226,534,636 - 6,534,760 (+)MAPPERmRatBN7.2
Rnor_6.023,862,695 - 3,862,818NCBIRnor6.0
Rnor_5.023,856,828 - 3,856,951UniSTSRnor5.0
RGSC_v3.424,146,568 - 4,146,691UniSTSRGSC3.4
Celera22,993,439 - 2,993,562UniSTS
Cytogenetic Map2q11UniSTS
BF405334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.226,295,485 - 6,295,667 (+)MAPPERmRatBN7.2
Rnor_6.023,624,692 - 3,624,873NCBIRnor6.0
Rnor_5.023,619,404 - 3,619,585UniSTSRnor5.0
RGSC_v3.423,880,884 - 3,881,065UniSTSRGSC3.4
Celera22,759,120 - 2,759,301UniSTS
Cytogenetic Map2q11UniSTS
AU048394  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.226,528,009 - 6,528,272 (+)MAPPERmRatBN7.2
Rnor_6.023,856,068 - 3,856,330NCBIRnor6.0
Rnor_5.023,850,201 - 3,850,463UniSTSRnor5.0
RGSC_v3.424,139,941 - 4,140,203UniSTSRGSC3.4
Celera22,986,812 - 2,987,074UniSTS
Cytogenetic Map2q11UniSTS
AU049754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.226,690,355 - 6,690,562 (+)MAPPERmRatBN7.2
Rnor_6.024,018,552 - 4,018,758NCBIRnor6.0
Rnor_5.024,012,765 - 4,012,971UniSTSRnor5.0
RGSC_v3.424,282,907 - 4,283,113UniSTSRGSC3.4
Celera23,149,272 - 3,149,478UniSTS
Cytogenetic Map2q11UniSTS
MARC_4375-4376:966894539:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.226,346,011 - 6,346,207 (+)MAPPERmRatBN7.2
mRatBN7.28104,259,008 - 104,259,208 (+)MAPPERmRatBN7.2
Rnor_6.08112,163,171 - 112,163,370NCBIRnor6.0
Rnor_6.023,673,616 - 3,673,811NCBIRnor6.0
Rnor_5.08111,551,771 - 111,551,970UniSTSRnor5.0
Rnor_5.023,668,328 - 3,668,523UniSTSRnor5.0
RGSC_v3.423,931,411 - 3,931,606UniSTSRGSC3.4
RGSC_v3.48108,697,562 - 108,697,761UniSTSRGSC3.4
Celera8103,634,329 - 103,634,528UniSTS
Celera22,809,645 - 2,809,840UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 165 88 87 56 91 56 6 345 190 11 143 75 91 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001376934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC097940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC125565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017828   ⟹   ENSRNOP00000017828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl27,803,382 - 8,493,586 (+)Ensembl
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)Ensembl
Rnor_6.0 Ensembl23,662,763 - 4,088,106 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000064743   ⟹   ENSRNOP00000058979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl28,020,945 - 8,491,796 (+)Ensembl
mRatBN7.2 Ensembl26,289,141 - 6,460,608 (+)Ensembl
Rnor_6.0 Ensembl23,750,094 - 3,824,139 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl23,618,346 - 3,861,178 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093593   ⟹   ENSRNOP00000076318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl27,803,382 - 8,493,596 (+)Ensembl
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)Ensembl
Rnor_6.0 Ensembl23,400,977 - 4,088,989 (+)Ensembl
RefSeq Acc Id: NM_001376934   ⟹   NP_001363863
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,803,484 - 8,493,596 (+)NCBI
mRatBN7.226,071,636 - 6,761,833 (+)NCBI
RefSeq Acc Id: XM_039102152   ⟹   XP_038958080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
mRatBN7.226,071,412 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102153   ⟹   XP_038958081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
mRatBN7.226,071,416 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102154   ⟹   XP_038958082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
mRatBN7.226,071,409 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102155   ⟹   XP_038958083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,556 - 8,493,588 (+)NCBI
mRatBN7.226,288,700 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102156   ⟹   XP_038958084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,585 - 8,493,588 (+)NCBI
mRatBN7.226,288,704 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102158   ⟹   XP_038958086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,557 - 8,493,588 (+)NCBI
mRatBN7.226,288,701 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_039102159   ⟹   XP_038958087
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,559 - 8,493,588 (+)NCBI
mRatBN7.226,288,702 - 6,761,830 (+)NCBI
RefSeq Acc Id: XM_063281693   ⟹   XP_063137763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281694   ⟹   XP_063137764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,489,833 (+)NCBI
RefSeq Acc Id: XM_063281695   ⟹   XP_063137765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281696   ⟹   XP_063137766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr827,798,968 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281697   ⟹   XP_063137767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,586 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281698   ⟹   XP_063137768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,045,877 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281699   ⟹   XP_063137769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,020,557 - 8,493,588 (+)NCBI
RefSeq Acc Id: XM_063281700   ⟹   XP_063137770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr828,152,279 - 8,493,588 (+)NCBI
Ensembl Acc Id: ENSRNOP00000076318   ⟸   ENSRNOT00000093593
Ensembl Acc Id: ENSRNOP00000017828   ⟸   ENSRNOT00000017828
Ensembl Acc Id: ENSRNOP00000058979   ⟸   ENSRNOT00000064743
RefSeq Acc Id: XP_038958082   ⟸   XM_039102154
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038958080   ⟸   XM_039102152
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958081   ⟸   XM_039102153
- Peptide Label: isoform X2
- UniProtKB: A0A286YFH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001363863   ⟸   NM_001376934
- UniProtKB: D4ABL6 (UniProtKB/Swiss-Prot),   A0A1W2Q6L3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958083   ⟸   XM_039102155
- Peptide Label: isoform X8
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958086   ⟸   XM_039102158
- Peptide Label: isoform X11
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958087   ⟸   XM_039102159
- Peptide Label: isoform X13
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958084   ⟸   XM_039102156
- Peptide Label: isoform X10
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137763   ⟸   XM_063281693
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137765   ⟸   XM_063281695
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063137766   ⟸   XM_063281696
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063137764   ⟸   XM_063281694
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063137769   ⟸   XM_063281699
- Peptide Label: isoform X12
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137767   ⟸   XM_063281697
- Peptide Label: isoform X9
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137768   ⟸   XM_063281698
- Peptide Label: isoform X11
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137770   ⟸   XM_063281700
- Peptide Label: isoform X14
- UniProtKB: A6I4G8 (UniProtKB/TrEMBL)
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ABL6-F1-model_v2 AlphaFold D4ABL6 1-946 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691040
Promoter ID:EPDNEW_R1562
Type:multiple initiation site
Name:Mctp1_1
Description:multiple C2 and transmembrane domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1563  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.023,400,886 - 3,400,946EPDNEW
RGD ID:13691041
Promoter ID:EPDNEW_R1563
Type:single initiation site
Name:Mctp1_2
Description:multiple C2 and transmembrane domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1562  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.023,618,310 - 3,618,370EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305199 AgrOrtholog
BioCyc Gene G2FUF-55076 BioCyc
Ensembl Genes ENSRNOG00000013282 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017828 ENTREZGENE
  ENSRNOT00000064743 ENTREZGENE
  ENSRNOT00000093593 ENTREZGENE
  ENSRNOT00000093593.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
NCBI Gene 309928 ENTREZGENE
PANTHER C2 DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  DYSFERLIN-RELATED UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
PhenoGen Mctp1 PhenoGen
PRINTS C2DOMAIN UniProtKB/Swiss-Prot
PROSITE PS50004 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013282 RatGTEx
SMART SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot
UniProt A0A1W2Q6L3 ENTREZGENE
  A0A286YFH5 ENTREZGENE, UniProtKB/TrEMBL
  A6I4G8 ENTREZGENE, UniProtKB/TrEMBL
  D3Z8Q9_RAT UniProtKB/TrEMBL
  D4ABL6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A1W2Q6L3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 Mctp1  multiple C2 and transmembrane domain containing 1  Mctp1  multiple C2 domains, transmembrane 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-05 Mctp1  multiple C2 domains, transmembrane 1  Mctp1-ps1  multiple C2 domains, transmembrane 1, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Mctp1-ps1  multiple C2 domains, transmembrane 1, pseudogene 1  Mctp1  multiple C2 domains, transmembrane 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mctp1  multiple C2 domains, transmembrane 1   Mctp1_predicted  multiple C2 domains, transmembrane 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Mctp1_predicted  multiple C2 domains, transmembrane 1 (predicted)  RGD1305199_predicted  similar to hypothetical protein FLJ22344 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305199_predicted  similar to hypothetical protein FLJ22344 (predicted)  LOC309928_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC309928_predicted  similar to hypothetical protein FLJ22344 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL