Atp6v0a4 (ATPase H+ transporting V0 subunit a4) - Rat Genome Database

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Gene: Atp6v0a4 (ATPase H+ transporting V0 subunit a4) Rattus norvegicus
Analyze
Symbol: Atp6v0a4
Name: ATPase H+ transporting V0 subunit a4
RGD ID: 1305055
Description: Predicted to enable ATPase binding activity. Predicted to be involved in several processes, including sensory perception of sound; synaptic vesicle lumen acidification; and vacuolar acidification. Predicted to act upstream of or within proton transmembrane transport. Located in apical plasma membrane. Is active in synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V0A4 (ATPase H+ transporting V0 subunit a4); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATPase, H+ transporting, lysosomal V0 subunit A; ATPase, H+ transporting, lysosomal V0 subunit A isoform 4; ATPase, H+ transporting, lysosomal V0 subunit A4; LOC296981; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a 4; V-type proton ATPase 116 kDa subunit a isoform 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8467,727,145 - 67,809,092 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl467,727,145 - 67,809,092 (-)EnsemblGRCr8
mRatBN7.2466,760,163 - 66,842,126 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl466,760,159 - 66,842,110 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx471,701,190 - 71,783,633 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0467,622,267 - 67,704,722 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0466,020,233 - 66,102,520 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0465,736,585 - 65,821,916 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl465,736,585 - 65,818,521 (-)Ensemblrn6Rnor6.0
Rnor_5.0465,554,091 - 65,639,218 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4465,588,970 - 65,671,150 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera461,781,600 - 61,863,525 (-)NCBICelera
RGSC_v3.1465,865,107 - 65,930,467 (-)NCBI
Cytogenetic Map4q23NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulation of the basolateral chloride/base exchangers AE1 and SLC26A7 in the kidney collecting duct in potassium depletion. Barone S, etal., Nephrol Dial Transplant. 2007 Dec;22(12):3462-70. Epub 2007 Sep 5.
2. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Vasopressin induces expression of the Cl-/HCO3- exchanger SLC26A7 in kidney medullary collecting ducts of Brattleboro rats. Petrovic S, etal., Am J Physiol Renal Physiol. 2006 May;290(5):F1194-201. Epub 2005 Dec 13.
8. Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis. Pietrement C, etal., Biol Reprod. 2006 Jan;74(1):185-94. Epub 2005 Sep 28.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116-kD subunit, cause recessive distal renal tubular acidosis with preserved hearing. Smith AN, etal., Nat Genet. 2000 Sep;26(1):71-5.
Additional References at PubMed
PMID:11495928   PMID:11498539   PMID:12414817   PMID:12649290   PMID:14638902   PMID:14675051   PMID:15385584   PMID:15800125   PMID:16177003   PMID:17360703   PMID:17897319   PMID:19056867  
PMID:19199708  


Genomics

Comparative Map Data
Atp6v0a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8467,727,145 - 67,809,092 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl467,727,145 - 67,809,092 (-)EnsemblGRCr8
mRatBN7.2466,760,163 - 66,842,126 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl466,760,159 - 66,842,110 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx471,701,190 - 71,783,633 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0467,622,267 - 67,704,722 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0466,020,233 - 66,102,520 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0465,736,585 - 65,821,916 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl465,736,585 - 65,818,521 (-)Ensemblrn6Rnor6.0
Rnor_5.0465,554,091 - 65,639,218 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4465,588,970 - 65,671,150 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera461,781,600 - 61,863,525 (-)NCBICelera
RGSC_v3.1465,865,107 - 65,930,467 (-)NCBI
Cytogenetic Map4q23NCBI
ATP6V0A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387138,706,294 - 138,798,196 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7138,706,289 - 138,799,672 (-)Ensemblhg38GRCh38
GRCh377138,391,039 - 138,482,941 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367138,041,579 - 138,133,481 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347137,848,294 - 137,916,037NCBI
Celera7133,128,799 - 133,220,749 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7132,702,109 - 132,793,853 (-)NCBIHuRef
CHM1_17138,324,308 - 138,416,716 (-)NCBICHM1_1
T2T-CHM13v2.07140,018,750 - 140,111,076 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27137,735,216 - 137,827,150 (-)NCBI
Atp6v0a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39638,025,418 - 38,101,521 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl638,025,418 - 38,101,521 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38638,048,483 - 38,124,586 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl638,048,483 - 38,124,586 (-)Ensemblmm10GRCm38
MGSCv37637,998,483 - 38,074,586 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36637,978,091 - 38,054,182 (-)NCBIMGSCv36mm8
Celera638,029,008 - 38,104,935 (-)NCBICelera
Cytogenetic Map6B1NCBI
cM Map617.5NCBI
Atp6v0a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554944,199,803 - 4,251,569 (+)Ensembl
ChiLan1.0NW_0049554944,174,542 - 4,251,450 (+)NCBIChiLan1.0ChiLan1.0
ATP6V0A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26175,521,062 - 175,586,363 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1727,531,314 - 27,596,491 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07130,665,997 - 130,758,537 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17143,154,382 - 143,210,822 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7143,154,712 - 143,218,802 (-)EnsemblpanPan2panpan1.1
ATP6V0A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1169,864,938 - 9,949,740 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl169,885,149 - 9,949,708 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1610,706,132 - 10,790,666 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0169,784,775 - 9,869,897 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl169,804,731 - 9,869,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1169,733,524 - 9,818,044 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0169,576,588 - 9,661,385 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0169,650,052 - 9,734,848 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atp6v0a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511816,113,322 - 16,180,145 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365923,039,705 - 3,086,844 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365923,039,911 - 3,083,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V0A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1810,919,422 - 10,966,410 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11810,868,208 - 10,966,801 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21811,330,847 - 11,430,526 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V0A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121107,407,831 - 107,505,300 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660724,258,221 - 4,314,820 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v0a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476519,149,589 - 19,194,158 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476519,149,353 - 19,219,242 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Atp6v0a4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16101,686,567 - 101,766,047 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Atp6v0a4
624 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:287
Count of miRNA genes:184
Interacting mature miRNAs:207
Transcripts:ENSRNOT00000064201
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45807987582597589Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45808014680212111Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45960331980216952Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat

Markers in Region
D4Got48  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8467,767,242 - 67,767,468 (+)Marker Load Pipeline
mRatBN7.2466,800,270 - 66,800,498 (+)MAPPERmRatBN7.2
Rnor_6.0465,776,688 - 65,776,913NCBIRnor6.0
Rnor_5.0465,594,194 - 65,594,419UniSTSRnor5.0
RGSC_v3.4465,628,995 - 65,629,221RGDRGSC3.4
RGSC_v3.4465,628,996 - 65,629,221UniSTSRGSC3.4
Celera461,821,604 - 61,821,829UniSTS
RGSC_v3.1465,905,125 - 65,905,351RGD
RH 3.4 Map4418.6RGD
RH 3.4 Map4418.6UniSTS
RH 2.0 Map4456.2RGD
Cytogenetic Map4q22UniSTS
BG377116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2466,760,398 - 66,760,560 (+)MAPPERmRatBN7.2
Rnor_6.0465,736,825 - 65,736,986NCBIRnor6.0
Rnor_5.0465,554,331 - 65,554,492UniSTSRnor5.0
RGSC_v3.4465,589,210 - 65,589,371UniSTSRGSC3.4
Celera461,781,840 - 61,782,001UniSTS
RH 3.4 Map4408.4UniSTS
Cytogenetic Map4q22UniSTS
RH133387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2466,840,893 - 66,841,104 (+)MAPPERmRatBN7.2
Rnor_6.0465,833,027 - 65,833,237NCBIRnor6.0
Rnor_6.0465,817,305 - 65,817,515NCBIRnor6.0
Rnor_5.0465,650,328 - 65,650,538UniSTSRnor5.0
Rnor_5.0465,634,606 - 65,634,816UniSTSRnor5.0
RGSC_v3.4465,669,920 - 65,670,130UniSTSRGSC3.4
Celera461,862,309 - 61,862,519UniSTS
RH 3.4 Map4403.22UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 11 57 157 90 90 59 30 59 6 282 119 9 135 81 91 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000064201   ⟹   ENSRNOP00000061018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl467,727,145 - 67,809,092 (-)Ensembl
mRatBN7.2 Ensembl466,760,159 - 66,842,110 (-)Ensembl
Rnor_6.0 Ensembl465,736,585 - 65,818,521 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079883   ⟹   ENSRNOP00000069768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl465,736,591 - 65,780,799 (-)Ensembl
RefSeq Acc Id: NM_001415838   ⟹   NP_001402767
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8467,727,145 - 67,809,092 (-)NCBI
mRatBN7.2466,760,163 - 66,842,126 (-)NCBI
RefSeq Acc Id: XM_063285748   ⟹   XP_063141818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8467,727,145 - 67,775,521 (-)NCBI
RefSeq Acc Id: XM_063285749   ⟹   XP_063141819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8467,727,145 - 67,774,264 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001402767 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141818 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141819 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15348 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061018
  ENSRNOP00000061018.2
Ensembl Acc Id: ENSRNOP00000069768   ⟸   ENSRNOT00000079883
Ensembl Acc Id: ENSRNOP00000061018   ⟸   ENSRNOT00000064201
RefSeq Acc Id: NP_001402767   ⟸   NM_001415838
- UniProtKB: A6IER1 (UniProtKB/TrEMBL),   D4A1H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141818   ⟸   XM_063285748
- Peptide Label: isoform X1
- UniProtKB: A6IER1 (UniProtKB/TrEMBL),   D4A1H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141819   ⟸   XM_063285749
- Peptide Label: isoform X1
- UniProtKB: A6IER1 (UniProtKB/TrEMBL),   D4A1H0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JW72-F1-model_v2 AlphaFold A0A0G2JW72 1-829 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692965
Promoter ID:EPDNEW_R3490
Type:initiation region
Name:Atp6v0a4_1
Description:ATPase H+ transporting V0 subunit a4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0465,818,537 - 65,818,597EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305055 AgrOrtholog
BioCyc Gene G2FUF-45218 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000013428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064201 ENTREZGENE
  ENSRNOT00000064201.5 UniProtKB/TrEMBL
InterPro ATPase_V0/A0-cplx_116kDa_su UniProtKB/TrEMBL
  V-type_ATPase_a UniProtKB/TrEMBL
NCBI Gene 296981 ENTREZGENE
PANTHER ATPase_V0/A0_116 UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE 116 KDA SUBUNIT A ISOFORM 4 UniProtKB/TrEMBL
Pfam V_ATPase_I UniProtKB/TrEMBL
PhenoGen Atp6v0a4 PhenoGen
PIRSF ATP6V0A1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013428 RatGTEx
UniProt A6IER1 ENTREZGENE, UniProtKB/TrEMBL
  D4A1H0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Atp6v0a4  ATPase H+ transporting V0 subunit a4  Atp6v0a4  ATPase, H+ transporting, lysosomal V0 subunit A4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Atp6v0a4  ATPase, H+ transporting, lysosomal V0 subunit A4  Atp6v0a4_predicted  ATPase, H+ transporting, lysosomal V0 subunit A isoform 4 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Atp6v0a4_predicted  ATPase, H+ transporting, lysosomal V0 subunit A isoform 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED