Lsm1 (LSM1 homolog, mRNA degradation associated) - Rat Genome Database

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Gene: Lsm1 (LSM1 homolog, mRNA degradation associated) Rattus norvegicus
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Symbol: Lsm1
Name: LSM1 homolog, mRNA degradation associated
RGD ID: 1304967
Description: Enables mRNA binding activity and pre-mRNA binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA and histone mRNA catabolic process. Predicted to act upstream of or within negative regulation of neuron differentiation and stem cell population maintenance. Located in axon; dendrite; and neuronal cell body. Part of ribonucleoprotein complex. Orthologous to human LSM1 (LSM1 homolog, mRNA degradation associated); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; fipronil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC364624; LSM1 homolog, U6 small nuclear RNA associated; LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); LSM1 mRNA degradation associated; LSM1, U6 small nuclear RNA associated; U6 snRNA-associated Sm-like protein LSm1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81672,980,075 - 72,991,581 (-)NCBIGRCr8
mRatBN7.21666,277,345 - 66,288,852 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,277,345 - 66,288,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1671,555,983 - 71,567,493 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01674,962,293 - 74,973,803 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01670,202,187 - 70,213,697 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01671,046,475 - 71,057,883 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,046,475 - 71,057,883 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,711,151 - 70,722,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,652,831 - 70,663,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11670,653,556 - 70,663,907 (-)NCBI
Celera1664,187,220 - 64,198,747 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1Ratcryptorchidism  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: CryptorchidismClinVarPMID:25741868 and PMID:31010896
Lsm1Ratdevelopmental and epileptic encephalopathy 11  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Complex neurodevelopmental disorderClinVarPMID:25741868 and PMID:31010896
Lsm1RatDevelopmental Disabilities  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:31010896
Lsm1Rathereditary spastic paraplegia 54  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 54ClinVarPMID:28492532
Lsm1Rathypogonadotropic hypogonadism 2 with or without anosmia  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hypogonadotropic hypogonadism 2 with or without anosmiaClinVarPMID:12627230 more ...
Lsm1Ratparaplegia  ISOLSM1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1Rat1,2-dimethylhydrazine multiple interactionsISOLsm1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of LSM1 mRNACTDPMID:22206623
Lsm1Rat17beta-estradiol increases expressionISOLsm1 (Mus musculus)6480464Estradiol results in increased expression of LSM1 mRNACTDPMID:39298647
Lsm1Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expressionISOLSM1 (Homo sapiens)6480464Metribolone results in increased expression of LSM1 mRNACTDPMID:17010196
Lsm1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOLsm1 (Mus musculus)64804642 more ...CTDPMID:30294300
Lsm1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOLsm1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of LSM1 mRNACTDPMID:17949056
Lsm1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of LSM1 mRNACTDPMID:21346803
Lsm1Rat4,4'-sulfonyldiphenol increases expressionISOLsm1 (Mus musculus)6480464bisphenol S results in increased expression of LSM1 mRNACTDPMID:39298647
Lsm1Ratacrolein multiple interactionsISOLSM1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of LSM1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of LSM1 mRNACTDPMID:32699268
Lsm1Ratacrylamide increases expressionISOLSM1 (Homo sapiens)6480464Acrylamide results in increased expression of LSM1 mRNACTDPMID:32763439
Lsm1Rataflatoxin B1 decreases methylationISOLSM1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of LSM1 geneCTDPMID:27153756
Lsm1Ratalpha-pinene multiple interactionsISOLSM1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of LSM1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of LSM1 mRNACTDPMID:32699268
Lsm1Rataristolochic acid A increases expressionISOLSM1 (Homo sapiens)6480464aristolochic acid I results in increased expression of LSM1 mRNACTDPMID:33212167
Lsm1Ratarsane multiple interactionsISOLSM1 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of LSM1 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of LSM1 mRNACTDPMID:39836092
Lsm1Ratarsenic atom multiple interactionsISOLSM1 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of LSM1 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of LSM1 mRNACTDPMID:39836092
Lsm1Ratarsenite(3-) multiple interactionsISOLSM1 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to LSM1 mRNA]CTDPMID:32406909
Lsm1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of LSM1 mRNACTDPMID:25181051
Lsm1Ratbisphenol A decreases expressionISOLSM1 (Homo sapiens)6480464bisphenol A results in decreased expression of LSM1 mRNACTDPMID:29275510
Lsm1Ratbutan-1-ol multiple interactionsISOLSM1 (Homo sapiens)6480464[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LSM1 mRNACTDPMID:29432896
Lsm1Ratcadmium atom multiple interactionsISOLSM1 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LSM1 mRNACTDPMID:35301059
Lsm1Ratcadmium dichloride multiple interactionsISOLSM1 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LSM1 mRNACTDPMID:35301059

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Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1Ratbiological_process  ND 159840704/2015: no relevant rat dataRGD 
Lsm1Ratdeadenylation-dependent decapping of nuclear-transcribed mRNA involved_inIBAPANTHER:PTN000400406 and SGD:S0000036601600115GO_REF:0000033GO_CentralGO_REF:0000033
Lsm1Rathistone mRNA catabolic process involved_inISOLSM1 (Homo sapiens)1624291 PMID:18172165RGDPMID:18172165
Lsm1RatmRNA processing involved_inIEAUniRule:UR0009317831600115GO_REF:0000104UniProtGO_REF:0000104
Lsm1RatmRNA processing involved_inIEAUniProtKB-KW:KW-05071600115GO_REF:0000043UniProtGO_REF:0000043
Lsm1Ratnegative regulation of neuron differentiation acts_upstream_of_or_withinISOLsm1 (Mus musculus)1624291 PMID:25456498RGDPMID:25456498
Lsm1Ratneuron differentiation acts_upstream_ofISOLsm1 (Mus musculus)1624291 PMID:25456498RGDPMID:25456498
Lsm1Ratnuclear-transcribed mRNA catabolic process involved_inIEAInterPro:IPR0341041600115GO_REF:0000002InterProGO_REF:0000002
Lsm1Ratstem cell population maintenance acts_upstream_of_or_withinISOLsm1 (Mus musculus)1624291 PMID:25456498RGDPMID:25456498
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Cellular Component
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1Rataxon  IDA 9999194 RGD 
Lsm1Ratcytoplasm located_inISOLSM1 (Homo sapiens)1624291 PMID:18559850RGDPMID:18559850
Lsm1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Lsm1Ratcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117
Lsm1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Lsm1Ratdendrite  IDA 9999194 RGD 
Lsm1RatLsm1-7-Pat1 complex part_ofIBAPANTHER:PTN000400406 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lsm1Ratneuronal cell body  IDA 9999194 RGD 
Lsm1Ratnucleus located_inISOLSM1 (Homo sapiens)1624291 PMID:18559850RGDPMID:18559850
Lsm1RatP-body located_inISOLsm1 (Mus musculus)1624291 PMID:25456498RGDPMID:25456498
Lsm1RatP-body located_inIEAUniRule:UR0009317831600115GO_REF:0000104UniProtGO_REF:0000104
Lsm1RatP-body located_inIEAUniProtKB-SubCell:SL-02301600115GO_REF:0000044UniProtGO_REF:0000044
Lsm1RatP-body is_active_inIBAMGI:1914457 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lsm1Ratribonucleoprotein complex  IDA 9999194 RGD 
Lsm1Ratribonucleoprotein complex part_ofIEAUniProtKB-KW:KW-06871600115GO_REF:0000043UniProtGO_REF:0000043
1 to 15 of 15 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1RatmRNA binding  IDA 9999194 RGD 
Lsm1RatmRNA binding enablesIBAPANTHER:PTN000400405 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lsm1Ratpre-mRNA binding  IDA 9999194 RGD 
Lsm1Ratprotein binding enablesISOLSM1 (Homo sapiens)1624291UniProtKB:A0PJW8 more ...RGDPMID:14667819 more ...
Lsm1Ratprotein binding enablesISOLsm1 (Mus musculus)1624291UniProtKB:Q7TMF2 and PMID:23202588RGDPMID:23202588
Lsm1RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Lsm1RatRNA binding enablesIEAInterPro:IPR0475751600115GO_REF:0000002InterProGO_REF:0000002

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lsm1RatRNA degradation pathway  IEA 6907045 KEGGrno:03018

#
Reference Title
Reference Citation
1. Dendritic LSm1/CBP80-mRNPs mark the early steps of transport commitment and translational control. di Penta A, etal., J Cell Biol. 2009 Feb 9;184(3):423-35. doi: 10.1083/jcb.200807033. Epub 2009 Feb 2.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:18172165   PMID:18559850   PMID:18719247   PMID:22658674   PMID:22681889   PMID:25456498  



Lsm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81672,980,075 - 72,991,581 (-)NCBIGRCr8
mRatBN7.21666,277,345 - 66,288,852 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,277,345 - 66,288,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1671,555,983 - 71,567,493 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01674,962,293 - 74,973,803 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01670,202,187 - 70,213,697 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01671,046,475 - 71,057,883 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,046,475 - 71,057,883 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,711,151 - 70,722,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,652,831 - 70,663,995 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11670,653,556 - 70,663,907 (-)NCBI
Celera1664,187,220 - 64,198,747 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
LSM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38838,163,321 - 38,176,730 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl838,163,335 - 38,176,730 (-)EnsemblGRCh38hg38GRCh38
GRCh37838,020,839 - 38,034,248 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,140,014 - 38,153,183 (-)NCBINCBI36Build 36hg18NCBI36
Build 34838,140,013 - 38,153,183NCBI
Celera836,973,393 - 36,986,562 (-)NCBICelera
Cytogenetic Map8p11.23NCBI
HuRef836,555,756 - 36,568,636 (-)NCBIHuRef
CHM1_1838,222,844 - 38,236,249 (-)NCBICHM1_1
T2T-CHM13v2.0838,440,300 - 38,453,709 (-)NCBIT2T-CHM13v2.0
Lsm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,275,326 - 26,294,003 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl826,275,316 - 26,294,003 (+)EnsemblGRCm39 Ensembl
GRCm38825,785,318 - 25,803,975 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,785,288 - 25,803,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv37826,896,063 - 26,914,447 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36827,250,852 - 27,269,520 (+)NCBIMGSCv36mm8
Celera827,253,809 - 27,272,186 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.17NCBI
Lsm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546313,773,869 - 13,788,784 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546313,775,639 - 13,788,784 (-)NCBIChiLan1.0ChiLan1.0
LSM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2756,726,906 - 56,739,998 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1832,443,915 - 32,457,154 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0837,465,986 - 37,479,186 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1834,642,938 - 34,656,142 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl834,642,938 - 34,656,142 (-)Ensemblpanpan1.1panPan2
LSM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11627,304,257 - 27,315,389 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1627,304,198 - 27,315,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1627,821,271 - 27,832,688 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01629,203,163 - 29,214,621 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1629,203,401 - 29,214,465 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11627,425,471 - 27,436,928 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01628,002,718 - 28,014,129 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01628,041,959 - 28,053,408 (+)NCBIUU_Cfam_GSD_1.0
Lsm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494349,909,516 - 49,915,246 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367101,545,790 - 1,552,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367101,546,027 - 1,551,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LSM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1548,348,648 - 48,365,106 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11548,348,653 - 48,360,004 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,604,059 - 55,615,385 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LSM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1836,184,928 - 36,198,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl836,182,380 - 36,198,704 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660525,791,244 - 5,805,004 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lsm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247805,473,041 - 5,483,300 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247805,473,172 - 5,483,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Lsm1
29 total Variants

Predicted Target Of
Summary Value
Count of predictions:427
Count of miRNA genes:217
Interacting mature miRNAs:255
Transcripts:ENSRNOT00000020721
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 14 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000020721   ⟹   ENSRNOP00000020721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1666,277,345 - 66,288,852 (-)Ensembl
Rnor_6.0 Ensembl1671,046,475 - 71,057,883 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118602   ⟹   ENSRNOP00000089972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1666,277,345 - 66,283,881 (-)Ensembl
RefSeq Acc Id: NM_001108876   ⟹   NP_001102346
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81672,980,075 - 72,991,581 (-)NCBI
mRatBN7.21666,277,345 - 66,288,852 (-)NCBI
Rnor_6.01671,046,475 - 71,057,883 (-)NCBI
Rnor_5.01670,711,151 - 70,722,559 (-)NCBI
RGSC_v3.41670,652,831 - 70,663,995 (-)RGD
Celera1664,187,220 - 64,198,747 (-)RGD
Sequence:
Protein RefSeqs NP_001102346 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM09069 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020721
  ENSRNOP00000020721.4
  ENSRNOP00000089972.1
RefSeq Acc Id: NP_001102346   ⟸   NM_001108876
- UniProtKB: D3ZWB1 (UniProtKB/TrEMBL),   A6IW03 (UniProtKB/TrEMBL),   A0A8I6GHU0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020721   ⟸   ENSRNOT00000020721
Ensembl Acc Id: ENSRNOP00000089972   ⟸   ENSRNOT00000118602
Sm

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZWB1-F1-model_v2 AlphaFold D3ZWB1 1-133 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700166
Promoter ID:EPDNEW_R10690
Type:initiation region
Name:Lsm1_1
Description:LSM1 homolog, mRNA degradation associated
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01671,057,642 - 71,057,702EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-10976 BioCyc
Ensembl Genes ENSRNOG00000015375 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020721 ENTREZGENE
  ENSRNOT00000020721.6 UniProtKB/TrEMBL
  ENSRNOT00000118602.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.100 UniProtKB/TrEMBL
InterPro IPR047575 UniProtKB/TrEMBL
  Lsm1 UniProtKB/TrEMBL
  LSM_domain UniProtKB/TrEMBL
  LSM_related_domain UniProtKB/TrEMBL
  PTHR15588 UniProtKB/TrEMBL
KEGG Report rno:364624 UniProtKB/TrEMBL
NCBI Gene 364624 ENTREZGENE
PANTHER PTHR15588 UniProtKB/TrEMBL
  U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 UniProtKB/TrEMBL
Pfam LSM UniProtKB/TrEMBL
PhenoGen Lsm1 PhenoGen
PROSITE PS52002 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015375 RatGTEx
SMART SM00651 UniProtKB/TrEMBL
Superfamily-SCOP Sm_like_riboprot UniProtKB/TrEMBL
UniProt A0A8I6GHU0 ENTREZGENE, UniProtKB/TrEMBL
  A6IW03 ENTREZGENE, UniProtKB/TrEMBL
  D3ZWB1 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-09 Lsm1  LSM1 homolog, mRNA degradation associated  Lsm1  LSM1 mRNA degradation associated  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-01 Lsm1  LSM1 mRNA degradation associated  Lsm1  LSM1, U6 small nuclear RNA associated  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-03-07 Lsm1  LSM1, U6 small nuclear RNA associated  Lsm1  LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lsm1  LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)   Lsm1_predicted  LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lsm1_predicted  LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED