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Gene: Atp6v1g3 (ATPase H+ transporting V1 subunit G3) Rattus norvegicus

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Symbol:

Atp6v1g3

Name:

ATPase H+ transporting V1 subunit G3

RGD ID:

1304635

Description:

Predicted to enable ATP hydrolysis activity; ATPase binding activity; and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in synaptic vesicle lumen acidification. Located in cytosol and plasma membrane. Orthologous to human ATP6V1G3 (ATPase H+ transporting V1 subunit G3); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ATPase, H transporting, lysosomal V1 subunit G3; ATPase, H+ transporting, lysosomal V1 subunit G3; ATPase, H+ transporting, V1 subunit G; ATPase, H+ transporting, V1 subunit G, isoform 3; LOC289407; V-type proton ATPase subunit G 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Atp6v1g3 (ATPase, H+ transporting, lysosomal V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Atp6v1g3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Atp6v1g3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Atp6v1g3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Atp6v1g3 (ATPase H+ transporting V1 subunit G3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ATP6V1G3 (ATPase H+ transporting V1 subunit G3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atp6v1g3 (ATPase, H+ transporting, lysosomal V1 subunit G3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atp6v1g3 (ATPase, H+ transporting, lysosomal V1 subunit G3)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	VMA10	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	VMA10	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Vha13	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Vha13	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	vha-10	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	vha-10	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	atp6v1g3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	atp6v1g3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	52,351,787 - 52,376,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	52,351,801 - 52,375,594 (+)	Ensembl				GRCr8
mRatBN7.2	13	49,800,256 - 49,825,247 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	49,794,222 - 49,825,247 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	52,418,239 - 52,432,667 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	53,706,130 - 53,720,558 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	50,973,369 - 50,987,782 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	55,265,794 - 55,288,651 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	55,274,199 - 55,288,651 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	60,297,386 - 60,321,789 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	51,462,070 - 51,476,522 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	50,095,450 - 50,109,898 (+)	NCBI		Celera
RGSC_v3.1	13	51,438,095 - 51,489,937 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (EXP)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

amphetamine (EXP)

Aroclor 1254 (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

chlordecone (ISO)

copper atom (EXP)

copper(0) (EXP)

dextran sulfate (ISO)

diquat (ISO)

fenvalerate (EXP)

gentamycin (EXP)

indometacin (EXP)

methimazole (EXP)

ozone (ISO)

PCB138 (ISO)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoatomic ion transport (IEA)

proton transmembrane transport (IEA)

synaptic vesicle lumen acidification (IBA)

Cellular Component

cytosol (IDA,IEA,ISO)

plasma membrane (IDA,IEA,ISO)

synaptic vesicle membrane (IBA)

vacuolar proton-transporting V-type ATPase complex (IEA)

vacuolar proton-transporting V-type ATPase, V1 domain (IBA)

Molecular Function

ATPase binding (IEA,ISO)

protein binding (ISO)

proton-transporting ATPase activity, rotational mechanism (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

oxidative phosphorylation pathway (IEA)

phagocytosis pathway (IEA)

rheumatoid arthritis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	V1 and V0 domains of the human H+-ATPase are linked by an interaction between the G and a subunits.	Norgett EE, etal., J Biol Chem. 2007 May 11;282(19):14421-7. Epub 2007 Mar 14.
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12527205

Genomics

Comparative Map Data

Atp6v1g3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	52,351,787 - 52,376,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	52,351,801 - 52,375,594 (+)	Ensembl				GRCr8
mRatBN7.2	13	49,800,256 - 49,825,247 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	49,794,222 - 49,825,247 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	52,418,239 - 52,432,667 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	53,706,130 - 53,720,558 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	50,973,369 - 50,987,782 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	55,265,794 - 55,288,651 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	55,274,199 - 55,288,651 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	60,297,386 - 60,321,789 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	51,462,070 - 51,476,522 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	50,095,450 - 50,109,898 (+)	NCBI		Celera
RGSC_v3.1	13	51,438,095 - 51,489,937 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

ATP6V1G3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	198,523,222 - 198,540,945 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	198,523,222 - 198,540,945 (-)	Ensembl			hg38	GRCh38
GRCh37	1	198,492,352 - 198,510,075 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	196,758,975 - 196,776,698 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	195,224,010 - 195,241,732	NCBI
Celera	1	171,614,921 - 171,632,643 (-)	NCBI		Celera
Cytogenetic Map	1	q31.3	NCBI
HuRef	1	169,659,548 - 169,677,275 (-)	NCBI		HuRef
CHM1_1	1	199,914,674 - 199,932,396 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	197,783,117 - 197,800,839 (-)	NCBI		T2T-CHM13v2.0

Atp6v1g3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	138,201,476 - 138,217,200 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	138,201,476 - 138,217,200 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	138,273,738 - 138,289,462 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	138,273,738 - 138,289,462 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	140,170,315 - 140,186,039 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	140,090,149 - 140,105,873 (+)	NCBI		MGSCv36	mm8
Celera	1	140,915,081 - 140,930,807 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	60.82	NCBI

Atp6v1g3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	34,910,498 - 34,927,745 (-)	Ensembl
ChiLan1.0	NW_004955406	34,910,498 - 34,927,745 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP6V1G3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	50,834,517 - 50,852,067 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	50,793,764 - 50,811,547 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	174,130,976 - 174,148,524 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	178,440,516 - 178,458,092 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	178,440,516 - 178,458,108 (-)	Ensembl			panPan2	panpan1.1

ATP6V1G3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	4,368,476 - 4,388,544 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	4,368,418 - 4,388,539 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	4,053,554 - 4,073,662 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	4,054,400 - 4,074,512 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	4,054,387 - 4,074,504 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	4,001,449 - 4,021,551 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	4,102,151 - 4,122,266 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	4,134,335 - 4,154,453 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Atp6v1g3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	76,227,144 - 76,242,234 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	5,461,760 - 5,476,879 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936567	5,461,760 - 5,476,893 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP6V1G3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	21,371,257 - 21,410,296 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	21,371,302 - 21,394,817 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	26,048,320 - 26,071,801 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP6V1G3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	30,867,341 - 30,886,380 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	30,868,161 - 30,886,540 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	31,756,940 - 31,775,447 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp6v1g3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624798	1,891,613 - 1,910,104 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624798	1,893,699 - 1,910,104 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Atp6v1g3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	18,635,875 - 18,650,264 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Atp6v1g3
156 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	667
Count of miRNA genes:	282
Interacting mature miRNAs:	364
Transcripts:	ENSRNOT00000029679
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	11866254	56866254	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	24335432	55601132	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	33794096	60914504	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	11866254	56866254	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
7	2	6	25	30	39	12	84	12	1	201	106	11	11	75	15	27

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272201	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029679 ⟹ ENSRNOP00000032126

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	52,351,801 - 52,375,594 (+)	Ensembl
mRatBN7.2 Ensembl	13	49,794,222 - 49,825,247 (+)	Ensembl
Rnor_6.0 Ensembl	13	55,274,199 - 55,288,651 (+)	Ensembl

RefSeq Acc Id:

NM_001105991 ⟹ NP_001099461

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	52,362,332 - 52,376,784 (+)	NCBI
mRatBN7.2	13	49,810,798 - 49,825,247 (+)	NCBI
Rnor_6.0	13	55,274,199 - 55,288,651 (+)	NCBI
Rnor_5.0	13	60,297,386 - 60,321,789 (+)	NCBI
RGSC_v3.4	13	51,462,070 - 51,476,522 (+)	RGD
Celera	13	50,095,450 - 50,109,898 (+)	RGD

Sequence:

show sequence

GACGTCACCTTCCTTGGAGCAAGACACCATGACCAGCCAGTCTCAGGGGATTCAACAGCTCCTG
CAAGCAGAGAAAAGGGCCAAAGACAAGCTGGATGAGGCAAAGAAGAGAAAAGGAAAGAGACTGA
GGCAAGCTAAGGAAGAAGCCGTGGCAGAGACCGACCAGTACAGAATGCAGAGGGAGAAGGAGTT
CCGCCTGAAGCAGTCTAAGATAATGGGCTCTCAGAGCCACCTCTCGGATGAACTCGAAGAGCAA
ACACTGGAGAAGATAAAGGAATTGAGCGGAAGCTACCACAAGTGTATGGACAGCGTGATTAAGC
AGCTGTTGAGCATGGTGTGTGAGATGAAACCAGAAGTCCACGTGAACTACAGAGCCACCAGCTG
AATGTACCTCGTCCTTCCAAGCCCACAGAAAGAGTCGGGATATGCTCTGTTAGGATGAATTGTC
CACCGAAGTTGCCTACACGCTTTCATGTCACGTATTTCTTGTGTGGCACGGAATTAAAAAATAA
ACAACATGGTGTCATTTCTCCTGGATGGCACTTAATCTGAAGCAAGTTGAGGAAAGGAAGGAAC
CTGCTTTTTAACATTGAAACAGCGATCGCTCTAGTACATTTCACACTTCTTTCTATTGGCTCAG
AGGACGCTTTATTAGGTATACTTCCTATGAAATAGGTTTTTAAAAGAGGAGAACGTAATTTTGA
TCCTTAGATACCTCTGAAATGAATATGCCAGGACTTTAATTAATTAATCGATGAGAAATACCAT
AGTACTCCACTGTCAGTCCAAAAGGCATTTTTTAAACTGTGGGAACAGAGACAGAAACAAAATG
TTGCAAGTCACCTTAGAGATGGATCCCATCACTGTTAGTTATCCCTGCCTAACTTCAAGTAACA
TAATGTCACTCTGTTTTAAGGGCATTTTTGAGGGAAAAAGTAAATATCTGAGAGTGTTGATCTC
TGGGTAGATTTTGTAGTTTGTAAAGAAGTGAACCTCCAACATAAAGAATTAGTATGTGGTATCC
TGGTCTCCATATTAAATGAGCTACATGCCCAACAGCTGTGTATATTGTTAGTTCAATGTATAAA
TTATCTTAGGCCTAGTGTGGAGAAAGTATTAGTTCCCTGTTCATAATGGCCATTAGAGTCTCAG
AACTTGACCCAGAGTTGTCTGGGAAACACTGGCAGCCCTGGATTCCCTCCGGCAGTGTGACACC
AGCATCTAGGCCTTTCACTTACTGCAAAGTCCGCACCAGGAGCAATAGCAGTATTGTTGGATGG
GGGAGGGGTGTTTGTTTGTTTGTGTTTTTGTTTTTAGTCAAGTTCTCACTCTATAGTTCGGACT
GTCCTGATTTCACCCTATGGCTCTGATTTCAAACTCATTGCGATCAACCTGCTCTGTGCTGAGT
ACTGGTATTACAGGCGTGTGCCACTCGCCCTCTTCCCAGCATTGCACTTTCAAGCACCATATGT
AGACAAATTTTAATTTCATAAGTTCATAAATATTTCTATCATTTTAAAATAATTTAGAATCCCA
TAGTCAATTTTATATTCAAAGTTGATGAGAAAATCGAAATTCCACTTGATTCCTTACTATTCCA
ACTTTATGAATAAGGAAAACTAAATCGAGTTAGTTTCTGGGATTTGTGTGATAGTGTTTTCCAG
TACAGGAAAAATAGCTTATTCCTTAATAAACAGAAAAGTCCAAAACATTCTGAAG

hide sequence

RefSeq Acc Id:

XM_017598760 ⟹ XP_017454249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	52,351,787 - 52,375,595 (+)	NCBI
mRatBN7.2	13	49,800,256 - 49,824,046 (+)	NCBI
Rnor_6.0	13	55,265,794 - 55,287,489 (+)	NCBI

Sequence:

show sequence

AGAGAGGAGCTGGGACCTGCAGGAACACCACACCAAGTCTCAGAGTTGTGTTTAAAGAAAGAAC
TTCACAGTGCTCACCTGGGCACCCAACTCTCTGATCCAATCTGGCAAGTTTGGACCAAACACCT
ATGTGTTCCCTGTTGACAAAACAAGCTGAGTTCGGTGGTGATCCATTAGGGAATAAAAGGGCCT
GTGCGTCCCAGCTTCCACAGACGTCACCTTCCTTGGAGCAAGACACCATGACCAGCCAGTCTCA
GGGGATTCAACAGCTCCTGCAAGCAGAGAAAAGGGCCAAAGACAAGCTGGATGAGGCAAAGAAG
AGAAAAGGAAAGAGACTGAGGCAAGCTAAGGAAGAAGCCGTGGCAGAGACCGACCAGTACAGAA
TGCAGAGGGAGAAGGAGTTCCGCCTGAAGCAGTCTAAGGTGAGGAACACAGCAGCCCCACCTCC
AGGTACTCAGATAATGGGCTCTCAGAGCCACCTCTCGGATGAACTCGAAGAGCAAACACTGGAG
AAGATAAAGGAATTGAGCGGAAGCTACCACAAGTGTATGGACAGCGTGATTAAGCAGCTGTTGA
GCATGGTGTGTGAGATGAAACCAGAAGTCCACGTGAACTACAGAGCCACCAGCTGAATGTACCT
CGTCCTTCCAAGCCCACAGAAAGAGTCGGGATATGCTCTGTTAGGATGAATTGTCCACCGAAGT
TGCCTACACGCTTTCATGTCACGTATTTCTTGTGTGGCACGGAATTAAAAAATAAACAACATGG
TGTCATTTCTCCTGGATGGCACTTAATCTGAAGCAA

hide sequence

RefSeq Acc Id:

XM_017598761 ⟹ XP_017454250

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	52,351,787 - 52,375,595 (+)	NCBI
mRatBN7.2	13	49,800,256 - 49,825,247 (+)	NCBI
Rnor_6.0	13	55,265,798 - 55,287,489 (+)	NCBI

Sequence:

show sequence

AGGAGCTGGGACCTGCAGGAACACCACACCAAGTCTCAGAGTTGTGTTTAAAGAAAGAACTTCA
CAGTGCTCACCTGGGCACCCAACTCTCTGATCCAATCTGGCAAGTTTGGACCAAACACCTATGT
GTTCCCTGTTGACAAAACAAGCTGAGTTCGGTGGTGATCCATTAGGGAATAAAAGGGCCTGTGC
GTCCCAGCTTCCACAGACGTCACCTTCCTTGGAGCAAGACACCATGACCAGCCAGTCTCAGGGG
ATTCAACAGCTCCTGCAAGCAGAGAAAAGGGCCAAAGACAAGCTGGATGAGGCAAAGAAGAGAA
AAGGAAAGAGACTGAGGCAAGCTAAGGAAGAAGCCGTGGCAGAGACCGACCAGTACAGAATGCA
GAGGGAGAAGGAGTTCCGCCTGAAGCAGTCTAAGATAATGGGCTCTCAGAGCCACCTCTCGGAT
GAACTCGAAGAGCAAACACTGGAGAAGATAAAGGAATTGAGCGGAAGCTACCACAAGTGTATGG
ACAGCGTGATTAAGCAGCTGTTGAGCATGGTGTGTGAGATGAAACCAGAAGTCCACGTGAACTA
CAGAGCCACCAGCTGAATGTACCTCGTCCTTCCAAGCCCACAGAAAGAGTCGGGATATGCTCTG
TTAGGATGAATTGTCCACCGAAGTTGCCTACACGCTTTCATGTCACGTATTTCTTGTGTGGCAC
GGAATTAAAAAATAAACAACATGGTGTCATTTCTCCTGGATGGCACTTAATCTGAAGCAA

hide sequence

RefSeq Acc Id:

XM_063272201 ⟹ XP_063128271

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	52,361,156 - 52,375,595 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099461	(Get FASTA)	NCBI Sequence Viewer
	XP_017454249	(Get FASTA)	NCBI Sequence Viewer
	XP_017454250	(Get FASTA)	NCBI Sequence Viewer
	XP_063128271	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09640	(Get FASTA)	NCBI Sequence Viewer
	EDM09641	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032126
	ENSRNOP00000032126.5

RefSeq Acc Id:	NP_001099461 ⟸ NM_001105991
- UniProtKB:	A6ICK6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAETDQYRMQREKEFRLKQSKIMG SQSHLSDELEEQTLEKIKELSGSYHKCMDSVIKQLLSMVCEMKPEVHVNYRATS hide sequence

RefSeq Acc Id:	XP_017454249 ⟸ XM_017598760
- Peptide Label:	isoform X1
- Sequence:	show sequence MCSLLTKQAEFGGDPLGNKRACASQLPQTSPSLEQDTMTSQSQGIQQLLQAEKRAKDKLDEAKK RKGKRLRQAKEEAVAETDQYRMQREKEFRLKQSKVRNTAAPPPGTQIMGSQSHLSDELEEQTLE KIKELSGSYHKCMDSVIKQLLSMVCEMKPEVHVNYRATS hide sequence

RefSeq Acc Id:	XP_017454250 ⟸ XM_017598761
- Peptide Label:	isoform X2
- Sequence:	show sequence MCSLLTKQAEFGGDPLGNKRACASQLPQTSPSLEQDTMTSQSQGIQQLLQAEKRAKDKLDEAKK RKGKRLRQAKEEAVAETDQYRMQREKEFRLKQSKIMGSQSHLSDELEEQTLEKIKELSGSYHKC MDSVIKQLLSMVCEMKPEVHVNYRATS hide sequence

Ensembl Acc Id:

ENSRNOP00000032126 ⟸ ENSRNOT00000029679

RefSeq Acc Id:	XP_063128271 ⟸ XM_063272201
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZTZ4-F1-model_v2	AlphaFold	D3ZTZ4	1-118	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698860

Promoter ID:

EPDNEW_R9385

Type:

single initiation site

Name:

Atp6v1g3_1

Description:

ATPase H+ transporting V1 subunit G3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	55,274,198 - 55,274,258	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304635	AgrOrtholog
BioCyc Gene	G2FUF-18106	BioCyc
BioCyc Pathway	PWY-7980 [ATP biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-7980	BioCyc
Ensembl Genes	ENSRNOG00000022480	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000029679	ENTREZGENE
	ENSRNOT00000029679.6	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.2950	UniProtKB/TrEMBL
InterPro	V-ATPase_G	UniProtKB/TrEMBL
KEGG Report	rno:289407	UniProtKB/TrEMBL
NCBI Gene	289407	ENTREZGENE
PANTHER	V-ATPase_G	UniProtKB/TrEMBL
	V-TYPE PROTON ATPASE SUBUNIT G 3	UniProtKB/TrEMBL
Pfam	V-ATPase_G	UniProtKB/TrEMBL
PhenoGen	Atp6v1g3	PhenoGen
RatGTEx	ENSRNOG00000022480	RatGTEx
UniProt	A6ICK6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZTZ4_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-25	Atp6v1g3	ATPase H+ transporting V1 subunit G3	Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-06-27	Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	Atp6v1g3	ATPase, H transporting, lysosomal V1 subunit G3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Atp6v1g3	ATPase, H transporting, lysosomal V1 subunit G3	Atp6v1g3_predicted	ATPase, H transporting, lysosomal V1 subunit G3 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Atp6v1g3_predicted	ATPase, H transporting, lysosomal V1 subunit G3 (predicted)		ATPase, H+ transporting, V1 subunit G, isoform 3 (predicted)	Name updated	1299863	APPROVED
2005-01-12	Atp6v1g3_predicted	ATPase, H+ transporting, V1 subunit G, isoform 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Annotations - KEGG (archival)

BioCyc Pathways