Jam3 (junctional adhesion molecule 3) - Rat Genome Database

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Pathways
Gene: Jam3 (junctional adhesion molecule 3) Rattus norvegicus
Analyze
Symbol: Jam3
Name: junctional adhesion molecule 3
RGD ID: 1303248
Description: Predicted to enable cell-cell adhesion mediator activity; identical protein binding activity; and integrin binding activity. Involved in axon regeneration. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; desmosome; and paranodal junction. Predicted to be part of filamentous actin and protein complex involved in cell adhesion. Predicted to be active in cell-cell contact zone and plasma membrane. Predicted to colocalize with bicellular tight junction. Biomarker of sciatic neuropathy. Orthologous to human JAM3 (junctional adhesion molecule 3); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: JAM-3; JAM-C; junctional adhesion molecule C; MGC94974
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8833,767,606 - 33,828,451 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl833,767,607 - 33,828,623 (-)EnsemblGRCr8
mRatBN7.2825,508,461 - 25,569,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx829,550,421 - 29,611,261 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0827,844,708 - 27,905,552 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0825,724,719 - 25,785,571 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,147,110 - 28,208,466 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)Ensemblrn6Rnor6.0
Rnor_5.0828,166,275 - 28,227,631 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4826,697,127 - 26,758,579 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera826,995,820 - 27,056,659 (-)NCBICelera
RGSC_v3.1826,697,127 - 26,758,579 (-)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetohydrazide  (ISO)
aconitine  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
anthracen-2-amine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
diethyl maleate  (EXP)
dimethylarsinic acid  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fipronil  (EXP)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gemcitabine  (ISO)
Heliotrine  (EXP)
indometacin  (ISO)
Lasiocarpine  (EXP)
lead(0)  (ISO)
methapyrilene  (ISO)
methylmercury(1+)  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
senecionine  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats. Avari P, etal., Brain Behav. 2012 Jul;2(4):402-14. doi: 10.1002/brb3.63.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Targeting of junctional adhesion molecule-C inhibits experimental choroidal neovascularization. Hou X, etal., Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1584-91. doi: 10.1167/iovs.11-9005. Print 2012 Mar.
4. Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Lamagna C, etal., Cancer Res. 2005 Jul 1;65(13):5703-10.
5. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. Ludwig RJ, etal., J Invest Dermatol. 2005 Nov;125(5):969-76.
6. Differential expression of junctional adhesion molecules in different stages of systemic sclerosis. Manetti M, etal., Arthritis Rheum. 2013 Jan;65(1):247-57. doi: 10.1002/art.37712.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. The proadhesive phenotype of systemic sclerosis skin promotes myeloid cell adhesion via ICAM-1 and VCAM-1. Rabquer BJ, etal., Rheumatology (Oxford). 2009 Jul;48(7):734-40. doi: 10.1093/rheumatology/kep091. Epub 2009 May 13.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11590146   PMID:11823489   PMID:12208882   PMID:15194813   PMID:15372036   PMID:15489334   PMID:15879142   PMID:16093349   PMID:17099249   PMID:17455169   PMID:17853450   PMID:18048693  
PMID:19060272   PMID:19109565   PMID:19342649   PMID:19461049   PMID:19740376   PMID:20592283   PMID:21097846   PMID:22871113   PMID:24357068   PMID:28196865  


Genomics

Comparative Map Data
Jam3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8833,767,606 - 33,828,451 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl833,767,607 - 33,828,623 (-)EnsemblGRCr8
mRatBN7.2825,508,461 - 25,569,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx829,550,421 - 29,611,261 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0827,844,708 - 27,905,552 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0825,724,719 - 25,785,571 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,147,110 - 28,208,466 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)Ensemblrn6Rnor6.0
Rnor_5.0828,166,275 - 28,227,631 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4826,697,127 - 26,758,579 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera826,995,820 - 27,056,659 (-)NCBICelera
RGSC_v3.1826,697,127 - 26,758,579 (-)NCBI
Cytogenetic Map8q13NCBI
JAM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811134,069,072 - 134,152,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11134,068,998 - 134,152,001 (+)Ensemblhg38GRCh38
GRCh3711133,938,967 - 134,021,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611133,444,030 - 133,526,861 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3411133,444,029 - 133,526,858NCBI
Celera11131,112,218 - 131,194,832 (+)NCBICelera
Cytogenetic Map11q25NCBI
HuRef11129,893,248 - 129,976,188 (+)NCBIHuRef
CHM1_111133,826,755 - 133,908,474 (+)NCBICHM1_1
T2T-CHM13v2.011134,112,013 - 134,194,140 (+)NCBIT2T-CHM13v2.0
Jam3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39927,008,680 - 27,066,739 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl927,008,680 - 27,066,717 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38927,097,384 - 27,155,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl927,097,384 - 27,155,421 (-)Ensemblmm10GRCm38
MGSCv37926,904,969 - 26,962,965 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36926,846,830 - 26,904,826 (-)NCBIMGSCv36mm8
Celera924,355,390 - 24,413,352 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map912.27NCBI
Jam3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541234,901,681 - 34,967,394 (+)Ensembl
ChiLan1.0NW_00495541234,901,850 - 34,967,394 (+)NCBIChiLan1.0ChiLan1.0
JAM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29134,787,560 - 134,878,062 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111135,892,480 - 135,977,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011128,916,024 - 129,006,497 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111132,783,580 - 132,864,657 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11132,783,580 - 132,864,657 (+)EnsemblpanPan2panpan1.1
JAM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.151,082,619 - 1,165,188 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl51,084,560 - 1,165,121 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha51,202,269 - 1,285,185 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.051,038,590 - 1,121,616 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl51,038,594 - 1,121,627 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.151,071,730 - 1,155,064 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.051,072,117 - 1,155,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.051,109,856 - 1,192,622 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Jam3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947115,840,860 - 115,913,401 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366841,692,089 - 1,762,087 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366841,689,594 - 1,762,066 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl960,613,400 - 60,738,924 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1960,629,245 - 60,738,979 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2967,205,386 - 67,284,770 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JAM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11125,136,963 - 125,211,424 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666043831,362 - 904,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jam3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248128,643,921 - 8,707,351 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248128,644,002 - 8,707,257 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Jam3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1822,994,398 - 23,054,310 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Jam3
212 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:244
Interacting mature miRNAs:301
Transcripts:ENSRNOT00000012247
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
RH143914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2825,508,834 - 25,508,991 (+)MAPPERmRatBN7.2
Rnor_6.0828,147,484 - 28,147,640NCBIRnor6.0
Rnor_5.0828,166,649 - 28,166,805UniSTSRnor5.0
RGSC_v3.4826,697,501 - 26,697,657UniSTSRGSC3.4
Celera826,996,194 - 26,996,350UniSTS
RH 3.4 Map8220.2UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 85 59 6 349 185 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012247   ⟹   ENSRNOP00000012247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl833,767,607 - 33,828,451 (-)Ensembl
mRatBN7.2 Ensembl825,508,473 - 25,569,303 (-)Ensembl
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100354   ⟹   ENSRNOP00000087591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl833,767,607 - 33,828,451 (-)Ensembl
mRatBN7.2 Ensembl825,508,473 - 25,569,303 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100661   ⟹   ENSRNOP00000094560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl833,767,607 - 33,828,434 (-)Ensembl
mRatBN7.2 Ensembl825,508,473 - 25,569,306 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101760   ⟹   ENSRNOP00000078492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110398   ⟹   ENSRNOP00000088272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl833,767,607 - 33,828,623 (-)Ensembl
mRatBN7.2 Ensembl825,508,473 - 25,553,573 (-)Ensembl
RefSeq Acc Id: NM_001004269   ⟹   NP_001004269
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8833,767,606 - 33,828,451 (-)NCBI
mRatBN7.2825,508,461 - 25,569,306 (-)NCBI
Rnor_6.0828,147,110 - 28,208,466 (-)NCBI
Rnor_5.0828,166,275 - 28,227,631 (-)NCBI
RGSC_v3.4826,697,127 - 26,758,579 (-)RGD
Celera826,995,820 - 27,056,659 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001004269 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79429 (Get FASTA)   NCBI Sequence Viewer  
  EDL83335 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012247
  ENSRNOP00000012247.4
GenBank Protein Q68FQ2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001004269   ⟸   NM_001004269
- Peptide Label: precursor
- UniProtKB: Q68FQ2 (UniProtKB/Swiss-Prot),   A6JYE0 (UniProtKB/TrEMBL),   A0A8I6ANI6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012247   ⟸   ENSRNOT00000012247
Ensembl Acc Id: ENSRNOP00000094560   ⟸   ENSRNOT00000100661
Ensembl Acc Id: ENSRNOP00000088272   ⟸   ENSRNOT00000110398
Ensembl Acc Id: ENSRNOP00000078492   ⟸   ENSRNOT00000101760
Ensembl Acc Id: ENSRNOP00000087591   ⟸   ENSRNOT00000100354
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FQ2-F1-model_v2 AlphaFold Q68FQ2 1-310 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695820
Promoter ID:EPDNEW_R6345
Type:initiation region
Name:Jam3_1
Description:junctional adhesion molecule 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0828,208,462 - 28,208,522EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303248 AgrOrtholog
BioCyc Gene G2FUF-31304 BioCyc
Ensembl Genes ENSRNOG00000009149 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012247 ENTREZGENE
  ENSRNOT00000012247.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7114667 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  JAM-C UniProtKB/Swiss-Prot
KEGG Report rno:315509 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94974 IMAGE-MGC_LOAD
NCBI Gene 315509 ENTREZGENE
PANTHER JUNCTIONAL ADHESION MOLECULE C UniProtKB/Swiss-Prot
  PTHR44598 UniProtKB/Swiss-Prot
Pfam Ig_3 UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
PhenoGen Jam3 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009149 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A8I6AGV1_RAT UniProtKB/TrEMBL
  A0A8I6AII5_RAT UniProtKB/TrEMBL
  A0A8I6ANI6 ENTREZGENE, UniProtKB/TrEMBL
  A6JYE0 ENTREZGENE, UniProtKB/TrEMBL
  JAM3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Jam3  junctional adhesion molecule 3      Symbol and Name status set to approved 1299863 APPROVED
2005-09-30 Jam3        Symbol and Name status set to provisional 70820 PROVISIONAL