Abca7 (ATP binding cassette subfamily A member 7) - Rat Genome Database

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Pathways
Gene: Abca7 (ATP binding cassette subfamily A member 7) Rattus norvegicus
Analyze
Symbol: Abca7
Name: ATP binding cassette subfamily A member 7
RGD ID: 1303134
Description: Predicted to enable ATPase-coupled transmembrane transporter activity; apolipoprotein A-I receptor activity; and floppase activity. Predicted to be involved in several processes, including phospholipid transport; positive regulation of transport; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including apical plasma membrane; phagocytic cup; and ruffle membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease 9. Orthologous to human ABCA7 (ATP binding cassette subfamily A member 7); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-binding cassette sub-family A member 7; ATP-binding cassette, sub-family A (ABC1), member 7; ATP-binding cassette, sub-family A, member 7; ATP-binding cassette, subfamily A (ABC1), member 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,342,092 - 10,362,094 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,342,092 - 10,361,989 (-)EnsemblGRCr8
mRatBN7.279,691,452 - 9,711,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,573,976 - 12,592,469 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,449,312 - 14,467,805 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,310,438 - 12,328,932 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,742,433 - 12,762,423 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,912,155 - 12,932,147 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,203,983 - 11,222,960 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera77,867,206 - 7,885,960 (-)NCBICelera
RGSC_v3.1711,203,982 - 11,222,960 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
maleic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
apical plasma membrane  (ISO)
cell junction  (IEA,ISO)
cell surface  (ISO,ISS)
cytoplasm  (IEA,ISO,ISS)
early endosome membrane  (IEA)
glial cell projection  (ISO,ISS)
Golgi apparatus  (IEA,ISO)
Golgi membrane  (IEA)
membrane  (IEA)
phagocytic cup  (IEA,ISO,ISS)
plasma membrane  (IEA,ISO)
ruffle membrane  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Cloning of rat ABCA7 and its preferential expression in platelets. Sasaki M, etal., Biochem Biophys Res Commun 2003 May 16;304(4):777-82.
Additional References at PubMed
PMID:12917409   PMID:14570867   PMID:15520449   PMID:16908670   PMID:18429932   PMID:20495215   PMID:23467355   PMID:24097981   PMID:26260791   PMID:27472885   PMID:28091533   PMID:29476059  


Genomics

Comparative Map Data
Abca7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,342,092 - 10,362,094 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,342,092 - 10,361,989 (-)EnsemblGRCr8
mRatBN7.279,691,452 - 9,711,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,573,976 - 12,592,469 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,449,312 - 14,467,805 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,310,438 - 12,328,932 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,742,433 - 12,762,423 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,912,155 - 12,932,147 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,203,983 - 11,222,960 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera77,867,206 - 7,885,960 (-)NCBICelera
RGSC_v3.1711,203,982 - 11,222,960 (-)NCBI
Cytogenetic Map7q11NCBI
ABCA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,040,107 - 1,065,572 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,039,997 - 1,065,572 (+)Ensemblhg38GRCh38
GRCh37191,040,106 - 1,065,571 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619991,102 - 1,016,571 (+)NCBIBuild 36Build 36hg18NCBI36
Celera19970,935 - 998,554 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19812,691 - 838,952 (+)NCBIHuRef
CHM1_1191,038,376 - 1,065,164 (+)NCBICHM1_1
T2T-CHM13v2.0191,002,776 - 1,030,237 (+)NCBIT2T-CHM13v2.0
Abca7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,832,328 - 79,851,406 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,832,328 - 79,851,406 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381079,996,453 - 80,015,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,996,494 - 80,015,572 (+)Ensemblmm10GRCm38
MGSCv371079,460,360 - 79,478,317 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361079,400,744 - 79,418,701 (+)NCBIMGSCv36mm8
Celera1081,012,422 - 81,030,379 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Abca7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,815,562 - 6,836,772 (-)Ensembl
ChiLan1.0NW_0049554956,818,002 - 6,838,177 (-)NCBIChiLan1.0ChiLan1.0
ABCA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,374,938 - 5,401,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,611,225 - 4,637,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01962,811 - 77,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1191,016,829 - 1,042,251 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,018,095 - 1,042,104 (+)EnsemblpanPan2panpan1.1
ABCA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,668,371 - 57,684,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,667,706 - 57,677,342 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2057,470,691 - 57,486,228 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02058,410,598 - 58,426,136 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,410,507 - 58,425,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,465,893 - 57,481,504 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,945,423 - 57,961,034 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,148,479 - 58,164,018 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Abca7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,357,348 - 217,374,569 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588461,389 - 477,229 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936588460,308 - 477,382 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,357,218 - 77,375,180 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1277,357,161 - 77,375,349 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,621,720 - 77,640,442 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16792,684 - 821,522 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6792,783 - 821,375 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660818,035,915 - 8,121,412 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abca7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,573,130 - 7,591,038 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248287,572,821 - 7,592,428 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Abca7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11154,860,216 - 154,880,239 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Abca7
533 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:115
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000064886
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
RH139906  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8710,342,140 - 10,342,477 (+)Marker Load Pipeline
mRatBN7.279,691,500 - 9,691,837 (+)MAPPERmRatBN7.2
Rnor_6.0712,742,482 - 12,742,818NCBIRnor6.0
Rnor_5.0712,912,204 - 12,912,540UniSTSRnor5.0
RGSC_v3.4711,203,950 - 11,204,286UniSTSRGSC3.4
Celera77,867,173 - 7,867,509UniSTS
RH 3.4 Map740.7UniSTS
Cytogenetic Map7q11UniSTS
BF390650  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8710,345,671 - 10,346,138 (+)Marker Load Pipeline
mRatBN7.279,695,031 - 9,695,498 (+)MAPPERmRatBN7.2
Rnor_6.0712,746,013 - 12,746,479NCBIRnor6.0
Rnor_5.0712,915,735 - 12,916,201UniSTSRnor5.0
RGSC_v3.4711,207,481 - 11,207,947UniSTSRGSC3.4
Celera77,870,704 - 7,871,170UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000064886   ⟹   ENSRNOP00000063805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,342,092 - 10,361,989 (-)Ensembl
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)Ensembl
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,743,992 - 12,746,090 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,746,039 - 12,746,952 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,742,479 - 12,746,546 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095800   ⟹   ENSRNOP00000095986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,342,092 - 10,361,989 (-)Ensembl
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097711   ⟹   ENSRNOP00000085552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,342,092 - 10,361,989 (-)Ensembl
mRatBN7.2 Ensembl79,691,452 - 9,711,425 (-)Ensembl
RefSeq Acc Id: NM_207598   ⟹   NP_997481
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,361,989 (-)NCBI
mRatBN7.279,691,452 - 9,711,353 (-)NCBI
Rnor_6.0712,742,515 - 12,761,261 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
RGSC_v3.4711,203,983 - 11,222,960 (-)RGD
Celera77,867,206 - 7,885,960 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240871   ⟹   XP_006240933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240872   ⟹   XP_006240934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,070 (-)NCBI
mRatBN7.279,691,452 - 9,711,457 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240874   ⟹   XP_006240936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,094 (-)NCBI
mRatBN7.279,691,452 - 9,711,466 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594715   ⟹   XP_017450204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078645   ⟹   XP_038934573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
RefSeq Acc Id: XM_039078646   ⟹   XP_038934574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,344,697 - 10,362,077 (-)NCBI
mRatBN7.279,694,082 - 9,711,444 (-)NCBI
RefSeq Acc Id: XM_063263170   ⟹   XP_063119240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,344,318 - 10,362,077 (-)NCBI
RefSeq Acc Id: XR_005486558
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,345,648 - 10,362,078 (-)NCBI
mRatBN7.279,695,008 - 9,711,444 (-)NCBI
RefSeq Acc Id: XR_010052951
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,343,651 - 10,362,077 (-)NCBI
RefSeq Acc Id: NP_997481   ⟸   NM_207598
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240936   ⟸   XM_006240874
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240934   ⟸   XM_006240872
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240933   ⟸   XM_006240871
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450204   ⟸   XM_017594715
- Peptide Label: isoform X3
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   A0A8I6A4A6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063805   ⟸   ENSRNOT00000064886
RefSeq Acc Id: XP_038934573   ⟸   XM_039078645
- Peptide Label: isoform X2
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934574   ⟸   XM_039078646
- Peptide Label: isoform X5
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000095986   ⟸   ENSRNOT00000095800
Ensembl Acc Id: ENSRNOP00000085552   ⟸   ENSRNOT00000097711
RefSeq Acc Id: XP_063119240   ⟸   XM_063263170
- Peptide Label: isoform X4
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot)
Protein Domains
ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TNJ2-F1-model_v2 AlphaFold Q7TNJ2 1-2170 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695047
Promoter ID:EPDNEW_R5572
Type:multiple initiation site
Name:Abca7_1
Description:ATP binding cassette subfamily A member 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,762,365 - 12,762,425EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303134 AgrOrtholog
BioCyc Gene G2FUF-34911 BioCyc
Ensembl Genes ENSRNOG00000012939 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000064886 ENTREZGENE
  ENSRNOT00000097711 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  ABC2_TM UniProtKB/Swiss-Prot
  ABC_transporter-like UniProtKB/Swiss-Prot
  ABC_transporter_CS UniProtKB/Swiss-Prot
  ABCA UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  R2_ABCA1-4-like UniProtKB/Swiss-Prot
KEGG Report rno:299609 UniProtKB/Swiss-Prot
NCBI Gene 299609 ENTREZGENE
PANTHER ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/Swiss-Prot
  PTHR19229 UniProtKB/Swiss-Prot
Pfam ABC2_membrane_3 UniProtKB/Swiss-Prot
  ABC_tran UniProtKB/Swiss-Prot
  R1_ABCA1 UniProtKB/Swiss-Prot
PhenoGen Abca7 PhenoGen
PROSITE ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012939 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6A4A6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASJ6_RAT UniProtKB/TrEMBL
  A6K8T5_RAT UniProtKB/TrEMBL
  ABCA7_RAT UniProtKB/Swiss-Prot
  F1LR67 ENTREZGENE, UniProtKB/TrEMBL
  Q7TNJ2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Abca7  ATP binding cassette subfamily A member 7  Abca7  ATP-binding cassette, subfamily A (ABC1), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-16 Abca7  ATP-binding cassette, subfamily A (ABC1), member 7  Abca7  ATP-binding cassette, sub-family A (ABC1), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Abca7  ATP-binding cassette, sub-family A (ABC1), member 7  ABCA7  ATP-binding cassette, sub-family A, member 7  Name updated 1299863 APPROVED
2005-02-14 ABCA7  ATP-binding cassette, sub-family A, member 7      Symbol and Name status set to provisional 70820 PROVISIONAL