Pgpep1 (pyroglutamyl-peptidase I) - Rat Genome Database

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Gene: Pgpep1 (pyroglutamyl-peptidase I) Rattus norvegicus
Analyze
Symbol: Pgpep1 (Ensembl: Mk1)
Name: pyroglutamyl-peptidase I (Ensembl:Mk1 protein)
RGD ID: 1303133
Description: Enables peptidase activity. Involved in protein catabolic process. Predicted to be located in cytosol. Orthologous to human PGPEP1 (pyroglutamyl-peptidase I); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 5-oxoprolyl-peptidase; PAP-I; PAPI; PGP-I; pyroglutamyl aminopeptidase I; pyroglutamyl-peptidase 1; pyrrolidone-carboxylate peptidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,804,408 - 18,817,466 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,805,009 - 18,817,462 (+)EnsemblGRCr8
mRatBN7.21618,770,563 - 18,782,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,812,708 - 18,822,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,945,640 - 19,955,013 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,865,663 - 18,875,020 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,521,989 - 20,531,254 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)Ensemblrn6Rnor6.0
Rnor_5.01620,379,057 - 20,388,085 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,276,650 - 19,285,828 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1618,962,969 - 18,971,980 (+)NCBICelera
RGSC_v3.11619,276,652 - 19,285,272 (+)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlormequat chloride  (EXP)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dimethylselenide  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
ketamine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol. Abe K, etal., Biol Pharm Bull 2003 Nov;26(11):1528-33.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12450739   PMID:12477932   PMID:12953169   PMID:21329657  


Genomics

Comparative Map Data
Pgpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,804,408 - 18,817,466 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1618,805,009 - 18,817,462 (+)EnsemblGRCr8
mRatBN7.21618,770,563 - 18,782,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1618,812,708 - 18,822,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,945,640 - 19,955,013 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,865,663 - 18,875,020 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,521,989 - 20,531,254 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)Ensemblrn6Rnor6.0
Rnor_5.01620,379,057 - 20,388,085 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,276,650 - 19,285,828 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1618,962,969 - 18,971,980 (+)NCBICelera
RGSC_v3.11619,276,652 - 19,285,272 (+)NCBI
Cytogenetic Map16p14NCBI
PGPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,340,598 - 18,369,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,340,587 - 18,369,950 (+)Ensemblhg38GRCh38
GRCh371918,451,408 - 18,480,760 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,312,408 - 18,341,763 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341918,312,449 - 18,338,156NCBI
Celera1918,353,176 - 18,382,554 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,015,122 - 18,044,514 (+)NCBIHuRef
CHM1_11918,451,669 - 18,480,994 (+)NCBICHM1_1
T2T-CHM13v2.01918,474,715 - 18,504,090 (+)NCBIT2T-CHM13v2.0
Pgpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,099,086 - 71,113,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,099,085 - 71,113,038 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38870,646,436 - 70,660,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,646,435 - 70,660,388 (-)Ensemblmm10GRCm38
MGSCv37873,173,010 - 73,183,580 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36873,578,100 - 73,588,670 (-)NCBIMGSCv36mm8
Celera873,205,873 - 73,216,439 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Pgpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,138,393 - 3,148,331 (-)Ensembl
ChiLan1.0NW_0049555243,138,393 - 3,148,321 (-)NCBIChiLan1.0ChiLan1.0
PGPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,201,216 - 23,230,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,209,543 - 22,255,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,819,337 - 17,848,683 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,792,335 - 18,819,031 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,792,341 - 18,812,697 (+)EnsemblpanPan2panpan1.1
PGPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,666,250 - 44,695,823 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,578,117 - 44,611,462 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02045,149,943 - 45,182,925 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,149,948 - 45,181,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,387,041 - 44,420,281 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,797,168 - 44,830,716 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,072,579 - 45,106,156 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pgpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,319,958 - 203,343,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,869,106 - 2,892,342 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,869,100 - 2,892,342 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,451,150 - 59,485,818 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1259,448,110 - 59,485,809 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PGPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,818,743 - 16,837,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,818,643 - 16,836,949 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660742,503,594 - 2,532,352 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,610,335 - 1,622,955 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249081,610,325 - 1,623,189 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pgpep1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11312,900,955 - 12,910,978 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pgpep1
51 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:319
Count of miRNA genes:186
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000026597
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000026597   ⟹   ENSRNOP00000026597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,771,021 - 18,783,478 (+)Ensembl
Rnor_6.0 Ensembl1620,521,956 - 20,531,396 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099711   ⟹   ENSRNOP00000095429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,772,911 - 18,783,478 (+)Ensembl
RefSeq Acc Id: NM_201988   ⟹   NP_973717
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,805,052 - 18,814,338 (+)NCBI
mRatBN7.21618,771,067 - 18,780,353 (+)NCBI
Rnor_6.01620,521,989 - 20,531,254 (+)NCBI
Rnor_5.01620,379,057 - 20,388,085 (+)NCBI
RGSC_v3.41619,276,650 - 19,285,828 (+)RGD
Celera1618,962,969 - 18,971,980 (+)RGD
Sequence:
RefSeq Acc Id: XM_039094320   ⟹   XP_038950248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,804,408 - 18,817,466 (+)NCBI
mRatBN7.21618,770,563 - 18,782,968 (+)NCBI
RefSeq Acc Id: XM_063275159   ⟹   XP_063131229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,804,639 - 18,817,466 (+)NCBI
Protein Sequences
Protein RefSeqs NP_973717 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950248 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131229 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98645 (Get FASTA)   NCBI Sequence Viewer  
  BAD01533 (Get FASTA)   NCBI Sequence Viewer  
  EDL90722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000026597.5
  ENSRNOP00000026601
GenBank Protein Q76IC5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_973717   ⟸   NM_201988
- UniProtKB: Q76IC5 (UniProtKB/Swiss-Prot),   A6KA15 (UniProtKB/TrEMBL),   A0A8I6B2L0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026597   ⟸   ENSRNOT00000026597
RefSeq Acc Id: XP_038950248   ⟸   XM_039094320
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000095429   ⟸   ENSRNOT00000099711
RefSeq Acc Id: XP_063131229   ⟸   XM_063275159
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76IC5-F1-model_v2 AlphaFold Q76IC5 1-209 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700021
Promoter ID:EPDNEW_R10544
Type:initiation region
Name:Pgpep1_1
Description:pyroglutamyl-peptidase I
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,521,969 - 20,522,029EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303133 AgrOrtholog
BioCyc Gene G2FUF-11796 BioCyc
BioCyc Pathway PWY-7942 [5-oxo-L-proline metabolism] BioCyc
BioCyc Pathway Image PWY-7942 BioCyc
Ensembl Genes ENSRNOG00000019639 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000019657 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026597.7 UniProtKB/Swiss-Prot
  ENSRNOT00000026601 ENTREZGENE
Gene3D-CATH 3.40.630.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7108516 IMAGE-MGC_LOAD
InterPro Peptidase_C15 UniProtKB/Swiss-Prot
  Peptidase_C15-like UniProtKB/Swiss-Prot
  Peptidase_C15-like_sf UniProtKB/Swiss-Prot
  PGPEP1_Cys_AS UniProtKB/Swiss-Prot
  PGPEP1_Glu_AS UniProtKB/Swiss-Prot
KEGG Report rno:290648 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112578 IMAGE-MGC_LOAD
NCBI Gene 290648 ENTREZGENE
PANTHER PTHR23402 UniProtKB/Swiss-Prot
  PTHR23402:SF16 UniProtKB/Swiss-Prot
Pfam Peptidase_C15 UniProtKB/Swiss-Prot
PhenoGen Pgpep1 PhenoGen
PIRSF Prld-crbxl_pptds UniProtKB/Swiss-Prot
PRINTS PYROGLUPTASE UniProtKB/Swiss-Prot
PROSITE PYRASE_CYS UniProtKB/Swiss-Prot
  PYRASE_GLU UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019639 RatGTEx
  ENSRNOG00000019657 RatGTEx
Superfamily-SCOP SSF53182 UniProtKB/Swiss-Prot
UniProt A0A8I6B2L0 ENTREZGENE
  A6KA15 ENTREZGENE, UniProtKB/TrEMBL
  F7FNJ2_RAT UniProtKB/TrEMBL
  PGPI_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Pgpep1  pyroglutamyl-peptidase I      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Pgpep1  pyroglutamyl-peptidase I      Symbol and Name status set to provisional 70820 PROVISIONAL