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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:scatter factor/hepatocyte growth factor signaling pathway
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Accession:PW:0000578 term browser browse the term
Definition:Scatter factor/hepatocyte growth factor signaling impacts on various biological processes such as proliferation and survival, morphogenesis and motility. SF/HGF and its receptor c-Met have also been implicated in tumor growth and angiogenesis.
Synonyms:related_synonym: SF/HGF signaling pathway;   Signaling by MET;   hepatocyte growth factor receptor signaling pathway
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scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene ISO RGD PMID:18175071 RGD:2299174 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO RGD PMID:14685170 RGD:1642762 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Gab1 GRB2-associated binding protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Grb2 growth factor receptor bound protein 2 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO
IMP		 RGD PMID:14685170 PMID:18175071 PMID:17065554 RGD:1642762, RGD:2299174, RGD:2317513 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Shc1 SHC adaptor protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
altered scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:20519133 PMID:20951313 PMID:21277552 PMID:19506583 RGD:5133241, RGD:5133242, RGD:5133243, RGD:5490965 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      growth factor signaling pathway 523
        scatter factor/hepatocyte growth factor signaling pathway 11
          altered scatter factor/hepatocyte growth factor signaling pathway 1
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