nuclear factor kappa B signaling pathway Gene, QTL, and Strain Annotations - Pathway Ontology

Help | FTP Download | Citing RGD | Contact Us

Keyword

ONTOLOGY REPORT

nuclear factor kappa B signaling pathway (PW:0000499)

NF-kB signaling plays an essential role in the mammalian immune system. The classical/canonical pathway, downstream but not exclusively of tumor necrosis factor/receptor 1 signaling, is regarded as a paradigm of NF-kB signaling. The classical and the non-classical pathway downstream of a subset of Tnf/receptor superfamily, share similar sets of core components, albeit in distinct ways. Collectively they regulate the exprssion of many genes.

There are 2 path(s) and 35 annotation(s) to this term. Annotations to this term and its descendants total 35.

View Interactive Pathway Diagram

ANNOTATIONS

You are currently viewing annotations to this term only, excluding more specific terms.
[ include annotations to more specific terms (i.e. this term's descendants) ]

nuclear factor kappa B signaling pathway

Gene Symbol	Gene Name	Evidence	Reference
CHUK	conserved helix-loop-helix ubiquitous kinase	TAS	RGD:2292172
Chuk	conserved helix-loop-helix ubiquitous kinase	ISS (from RGD:1315401)	RGD:2292172
Chuk	conserved helix-loop-helix ubiquitous kinase	ISS (from RGD:1315401)	RGD:2292172
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	TAS	RGD:2292172
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	TAS	RGD:2292172
Ikbkb	inhibitor of kappaB kinase beta	ISS (from RGD:733968)	RGD:2292172
Ikbkb	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	ISS (from RGD:733968)	RGD:2292172
Ikbkg	inhibitor of kappaB kinase gamma	ISS (from RGD:1347094)	RGD:2292172
Ikbkg	inhibitor of kappaB kinase gamma	ISS (from RGD:1347094)	RGD:2292172
MAP3K14	mitogen-activated protein kinase kinase kinase 14	TAS	RGD:2292172
Map3k14	mitogen-activated protein kinase kinase kinase 14	ISS (from RGD:1321416)	RGD:2292172
Map3k14	mitogen-activated protein kinase kinase kinase 14	ISS (from RGD:1321416)	RGD:2292172
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	TAS	RGD:2292172
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	TAS	RGD:2292172
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	TAS	RGD:2292172
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	TAS	RGD:2292172
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	TAS	RGD:2292172
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	ISS (from RGD:730892)	RGD:2292172
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	ISS (from RGD:730892)	RGD:2292172
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	ISS (from RGD1316230)	RGD:2292172
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	ISS (from RGD1316230)	RGD:2292172
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	ISS (from RGD:736440)	RGD:2292172
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	ISS (from RGD:736440)	RGD:2292172
Nfkbib	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	ISS (from RGD:732611)	RGD:2292172
Nfkbib	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	ISS (from RGD:732611)	RGD:2292172
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	ISS (from RGD:1352834)	RGD:2292172
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	ISS (from RGD:1352834)	RGD:2292172
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	TAS	RGD:2292172
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	TAS	RGD:2292172
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	TAS	RGD:2292172
Rel	reticuloendotheliosis oncogene	ISS (from RGD:1322580)	RGD:2292172
Rel	v-rel reticuloendotheliosis viral oncogene homolog (avian)	ISS (from RGD:1322580)	RGD:2292172
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	ISS (from RGD:1352761)	RGD:2292172
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	ISS (from RGD:1352761)	RGD:2292172
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	ISS (from RGD:1353567)	RGD:2292172
TNF	tumor necrosis factor (TNF superfamily, member 2)	ISS (from RGD:3876)	RGD:1580210
Tnf	tumor necrosis factor (TNF superfamily, member 2)	IGI	RGD:1580210
Tnf	tumor necrosis factor	ISS (from RGD:3876)	RGD:1580210

To access information on a term, click the item in the Term column. To browse the ontology at a particular point, click the corresponding

in the second column. The C column indicates the number of objects annotated to the term, while the T column indicates the number of annotations to the term and its decendants.

Go to path: [ 1 ][ 2 ][ back to top ]
Term	C	T
Pathway Ontology	0	7709
signaling pathway	0	3287
nuclear factor kappa B signaling pathway +	35	35
Go to path: [ 1 ][ 2 ][ back to top ]
Term	C	T
Pathway Ontology	0	7709
regulatory pathway	0	1992
pathways of replication, gene expression, protein biosynthesis	0	307
transcription pathway	0	35
nuclear factor kappa B signaling pathway +	35	35

Go to annotations

Search Ontology