Ccnf (cyclin F) - Rat Genome Database

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Gene: Ccnf (cyclin F) Rattus norvegicus
Analyze
Symbol: Ccnf
Name: cyclin F
RGD ID: 67401
Description: Predicted to enable anaphase-promoting complex binding activity and cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle phase transition; and negative regulation of centrosome duplication. Predicted to act upstream of or within placenta development and re-entry into mitotic cell cycle. Predicted to be located in cell junction and centriole. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in centrosome; cytoplasm; and nucleus. Orthologous to human CCNF (cyclin F); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cyclin-F
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,757,884 - 13,783,669 (-)NCBIGRCr8
mRatBN7.21013,253,073 - 13,279,140 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,253,380 - 13,279,101 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,998,796 - 18,024,039 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,487,635 - 17,512,878 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,986,360 - 13,012,061 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,594,687 - 13,619,935 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,594,687 - 13,619,935 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,410,718 - 13,435,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,474,659 - 13,500,979 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,475,698 - 13,500,979 (-)NCBI
Celera1012,939,775 - 12,964,974 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpromazine  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
D-glucitol  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
fenofibrate  (EXP)
formaldehyde  (ISO)
furan  (EXP)
hydroquinone  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
irinotecan  (ISO)
leflunomide  (EXP,ISO)
lidocaine  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methylisothiazolinone  (ISO)
microcystin-LR  (ISO)
N-nitrosodiethylamine  (ISO)
nickel dichloride  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP,ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14993286   PMID:19028597   PMID:20596027  


Genomics

Comparative Map Data
Ccnf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,757,884 - 13,783,669 (-)NCBIGRCr8
mRatBN7.21013,253,073 - 13,279,140 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,253,380 - 13,279,101 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,998,796 - 18,024,039 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,487,635 - 17,512,878 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,986,360 - 13,012,061 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,594,687 - 13,619,935 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,594,687 - 13,619,935 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,410,718 - 13,435,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,474,659 - 13,500,979 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,475,698 - 13,500,979 (-)NCBI
Celera1012,939,775 - 12,964,974 (-)NCBICelera
Cytogenetic Map10q12NCBI
CCNF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,429,447 - 2,458,854 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,429,394 - 2,458,854 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,479,448 - 2,508,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,419,396 - 2,448,860 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,419,440 - 2,448,856NCBI
Celera162,693,713 - 2,723,233 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,405,092 - 2,434,482 (+)NCBIHuRef
CHM1_1162,479,499 - 2,508,753 (+)NCBICHM1_1
T2T-CHM13v2.0162,451,862 - 2,480,982 (+)NCBIT2T-CHM13v2.0
Ccnf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,441,518 - 24,470,333 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,441,172 - 24,470,458 (-)EnsemblGRCm39 Ensembl
GRCm381724,223,230 - 24,251,409 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,222,198 - 24,251,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,360,177 - 24,388,354 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,950,149 - 23,978,947 (-)NCBIMGSCv36mm8
Celera1724,728,662 - 24,756,723 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.32NCBI
Ccnf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,865,954 - 14,890,709 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,864,935 - 14,890,802 (-)NCBIChiLan1.0ChiLan1.0
CCNF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,930,446 - 2,960,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,711,523 - 6,741,090 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,285,379 - 1,314,972 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,526,035 - 2,558,265 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,529,371 - 2,556,438 (+)Ensemblpanpan1.1panPan2
CCNF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,572,883 - 38,592,465 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,574,234 - 38,592,435 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,811,687 - 39,830,658 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,882,560 - 38,901,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,882,570 - 38,901,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,567,686 - 38,586,705 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,540,319 - 38,559,293 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,016,472 - 39,035,536 (-)NCBIUU_Cfam_GSD_1.0
Ccnf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,088,821 - 105,112,566 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,596,766 - 1,620,643 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,596,897 - 1,620,588 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,585,607 - 39,603,079 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,585,597 - 39,603,088 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,640,736 - 42,658,423 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,302,249 - 2,336,188 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,302,341 - 2,335,270 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,701,622 - 28,738,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccnf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824181,735 - 204,029 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824181,696 - 204,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccnf
142 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:121
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000064392
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat

Markers in Region
D10Arb23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,265,081 - 13,265,233 (+)MAPPERmRatBN7.2
Rnor_6.01013,605,902 - 13,606,053NCBIRnor6.0
Rnor_5.01013,421,933 - 13,422,084UniSTSRnor5.0
RGSC_v3.41013,486,300 - 13,486,451UniSTSRGSC3.4
RGSC_v3.11013,486,299 - 13,486,452RGD
Celera1012,950,990 - 12,951,141UniSTS
Cytogenetic Map10q12UniSTS
RH128560  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2630,893,747 - 30,893,954 (+)MAPPERmRatBN7.2
mRatBN7.21013,254,216 - 13,254,432 (+)MAPPERmRatBN7.2
Rnor_6.01013,595,037 - 13,595,252NCBIRnor6.0
Rnor_6.0633,226,252 - 33,226,458NCBIRnor6.0
Rnor_5.01013,411,068 - 13,411,283UniSTSRnor5.0
Rnor_5.0643,005,793 - 43,005,999UniSTSRnor5.0
RGSC_v3.4631,557,848 - 31,558,054UniSTSRGSC3.4
RGSC_v3.41013,475,009 - 13,475,224UniSTSRGSC3.4
Celera1012,940,125 - 12,940,340UniSTS
Celera630,349,095 - 30,349,301UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 26 28 22 13 22 43 18 33 1
Low 1 10 27 19 6 19 2 2 31 13 8 10 2
Below cutoff 7 2 6 9 4 6

Sequence


RefSeq Acc Id: ENSRNOT00000064392   ⟹   ENSRNOP00000060445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,253,380 - 13,279,101 (-)Ensembl
Rnor_6.0 Ensembl1013,594,687 - 13,619,935 (-)Ensembl
RefSeq Acc Id: NM_001100474   ⟹   NP_001093944
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,758,421 - 13,783,669 (-)NCBI
mRatBN7.21013,253,867 - 13,279,120 (-)NCBI
Rnor_6.01013,594,687 - 13,619,935 (-)NCBI
Rnor_5.01013,410,718 - 13,435,965 (-)NCBI
RGSC_v3.41013,474,659 - 13,500,979 (-)RGD
Celera1012,939,775 - 12,964,974 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085084   ⟹   XP_038941012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,757,884 - 13,783,653 (-)NCBI
mRatBN7.21013,253,073 - 13,279,140 (-)NCBI
RefSeq Acc Id: XM_063268339   ⟹   XP_063124409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,757,884 - 13,773,405 (-)NCBI
RefSeq Acc Id: NP_001093944   ⟸   NM_001100474
- UniProtKB: D3ZCW7 (UniProtKB/Swiss-Prot),   Q8K4F8 (UniProtKB/Swiss-Prot),   A6HCR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000060445   ⟸   ENSRNOT00000064392
RefSeq Acc Id: XP_038941012   ⟸   XM_039085084
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063124409   ⟸   XM_063268339
- Peptide Label: isoform X2
Protein Domains
Cyclin N-terminal   F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K4F8-F1-model_v2 AlphaFold Q8K4F8 1-780 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697006
Promoter ID:EPDNEW_R7531
Type:initiation region
Name:Ccnf_1
Description:cyclin F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01013,619,953 - 13,620,013EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:67401 AgrOrtholog
BioCyc Gene G2FUF-25867 BioCyc
Ensembl Genes ENSRNOG00000007483 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055027030 UniProtKB/Swiss-Prot
  ENSRNOG00060009823 UniProtKB/Swiss-Prot
  ENSRNOG00065010359 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000064392 ENTREZGENE
  ENSRNOT00000064392.2 UniProtKB/Swiss-Prot
  ENSRNOT00055046710 UniProtKB/Swiss-Prot
  ENSRNOT00060016606 UniProtKB/Swiss-Prot
  ENSRNOT00065016761 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
  Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetratricopeptide repeat domain UniProtKB/TrEMBL
InterPro Cyclin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_C-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclins_cyclin-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117524 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 117524 ENTREZGENE
PANTHER CYCLIN-F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYCLINS UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam Cyclin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccnf PhenoGen
PROSITE CYCLINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007483 RatGTEx
  ENSRNOG00055027030 RatGTEx
  ENSRNOG00060009823 RatGTEx
  ENSRNOG00065010359 RatGTEx
SMART CYCLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Cyclin-like UniProtKB/TrEMBL
  F-box domain UniProtKB/TrEMBL
  SSF47954 UniProtKB/Swiss-Prot
  SSF81383 UniProtKB/Swiss-Prot
UniProt A6HCR2 ENTREZGENE, UniProtKB/TrEMBL
  CCNF_RAT UniProtKB/Swiss-Prot
  D3ZCW7 ENTREZGENE
  Q8K4F8 ENTREZGENE
UniProt Secondary D3ZCW7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ccnf  cyclin F      Symbol and Name status set to approved 70586 APPROVED
2001-10-22 Ccnf  Cyclin F      Added name, no other information available 68916 RESERVED