Tmbim1 (transmembrane BAX inhibitor motif containing 1) - Rat Genome Database

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Gene: Tmbim1 (transmembrane BAX inhibitor motif containing 1) Rattus norvegicus
Analyze
Symbol: Tmbim1
Name: transmembrane BAX inhibitor motif containing 1
RGD ID: 1359409
Description: Predicted to enable death receptor binding activity. Predicted to be involved in negative regulation of protein localization to plasma membrane; negative regulation of signal transduction; and positive regulation of blood vessel remodeling. Predicted to be located in endosome membrane and lysosomal membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and membrane. Orthologous to human TMBIM1 (transmembrane BAX inhibitor motif containing 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC94053; similar to RECS1; transmembrane BAX inhibitor motif-containing protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,320,972 - 83,338,469 (-)NCBIGRCr8
mRatBN7.2975,871,835 - 75,889,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,871,835 - 75,889,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,317,374 - 84,334,544 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,446,295 - 89,463,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,832,511 - 87,849,679 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,569,289 - 81,586,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,569,289 - 81,586,553 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,335,836 - 81,353,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,614,825 - 73,632,005 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,761,807 - 73,770,449 (-)NCBI
Celera973,448,320 - 73,465,500 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
ciglitazone  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diquat  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
furan  (EXP)
inulin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
leflunomide  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
omeprazole  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
resveratrol  (ISO)
sodium arsenate  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16607040   PMID:16636500   PMID:17897319   PMID:19056867   PMID:21107705   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Tmbim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,320,972 - 83,338,469 (-)NCBIGRCr8
mRatBN7.2975,871,835 - 75,889,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,871,835 - 75,889,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,317,374 - 84,334,544 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,446,295 - 89,463,469 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,832,511 - 87,849,679 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,569,289 - 81,586,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,569,289 - 81,586,553 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,335,836 - 81,353,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,614,825 - 73,632,005 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,761,807 - 73,770,449 (-)NCBI
Celera973,448,320 - 73,465,500 (-)NCBICelera
Cytogenetic Map9q33NCBI
TMBIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,274,197 - 218,292,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,274,197 - 218,292,586 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,138,920 - 219,157,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,847,161 - 218,865,524 (-)NCBINCBI36Build 36hg18NCBI36
Celera2212,905,492 - 212,923,864 (-)NCBICelera
Cytogenetic Map2q35ENTREZGENE
HuRef2210,992,006 - 211,010,384 (-)NCBIHuRef
CHM1_12219,145,398 - 219,163,764 (-)NCBICHM1_1
T2T-CHM13v2.02218,759,890 - 218,778,207 (-)NCBIT2T-CHM13v2.0
Tmbim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,327,406 - 74,343,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,327,406 - 74,344,781 (-)EnsemblGRCm39 Ensembl
GRCm38174,288,247 - 74,304,336 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,288,247 - 74,305,622 (-)EnsemblGRCm38mm10GRCm38
MGSCv37174,334,821 - 74,350,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,221,461 - 74,237,367 (-)NCBIMGSCv36mm8
Celera174,849,600 - 74,865,677 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.53NCBI
Tmbim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,092,522 - 15,099,021 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,083,179 - 15,100,197 (+)NCBIChiLan1.0ChiLan1.0
TMBIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213120,906,392 - 120,924,762 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B120,921,356 - 120,939,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,533,578 - 105,551,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,131,476 - 224,149,669 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,131,478 - 224,143,170 (-)Ensemblpanpan1.1panPan2
TMBIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,952,145 - 24,983,477 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,952,902 - 24,958,137 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,772,307 - 25,789,205 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03724,968,200 - 24,985,133 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,968,204 - 24,985,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,873,526 - 24,890,468 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,807,781 - 24,824,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,827,421 - 24,844,375 (-)NCBIUU_Cfam_GSD_1.0
Tmbim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,460,373 - 174,477,277 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569800,760 - 820,271 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936569803,154 - 820,000 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMBIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,348,735 - 120,365,007 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,348,740 - 120,365,055 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMBIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,155,823 - 104,174,135 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,155,185 - 104,163,793 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604095,227,649 - 95,245,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmbim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,735,497 - 6,756,093 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,736,216 - 6,757,285 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmbim1
41 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:504
Count of miRNA genes:252
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000019848
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat

Markers in Region
RH130780  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2975,871,995 - 75,872,213 (+)MAPPERmRatBN7.2
Rnor_6.0981,569,450 - 81,569,667NCBIRnor6.0
Rnor_5.0981,335,997 - 81,336,214UniSTSRnor5.0
RGSC_v3.4973,614,986 - 73,615,203UniSTSRGSC3.4
Celera973,448,481 - 73,448,698UniSTS
RH 3.4 Map9708.89UniSTS
Cytogenetic Map9q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 4 1 12 14 24 27 11
Low 39 56 41 7 41 8 11 60 11 14 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019848   ⟹   ENSRNOP00000019848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,871,835 - 75,889,069 (-)Ensembl
Rnor_6.0 Ensembl981,569,289 - 81,586,469 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl981,576,139 - 81,586,553 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl981,574,173 - 81,575,900 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl981,577,320 - 81,579,875 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089952   ⟹   ENSRNOP00000073792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,871,840 - 75,889,060 (-)Ensembl
Rnor_6.0 Ensembl981,575,197 - 81,586,116 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089985   ⟹   ENSRNOP00000072508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl975,871,852 - 75,889,060 (-)Ensembl
Rnor_6.0 Ensembl981,574,174 - 81,579,772 (-)Ensembl
RefSeq Acc Id: NM_001007713   ⟹   NP_001007714
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,972 - 83,338,152 (-)NCBI
mRatBN7.2975,871,835 - 75,889,016 (-)NCBI
Rnor_6.0981,569,289 - 81,586,469 (-)NCBI
Rnor_5.0981,335,836 - 81,353,016 (-)NCBI
RGSC_v3.4973,614,825 - 73,632,005 (-)RGD
Celera973,448,320 - 73,465,500 (-)RGD
Sequence:
RefSeq Acc Id: XM_017596477   ⟹   XP_017451966
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,334,921 (-)NCBI
mRatBN7.2975,871,841 - 75,885,801 (-)NCBI
Rnor_6.0981,569,289 - 81,582,650 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596478   ⟹   XP_017451967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,334,920 (-)NCBI
mRatBN7.2975,871,841 - 75,885,799 (-)NCBI
Rnor_6.0981,569,289 - 81,582,650 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596479   ⟹   XP_017451968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,334,921 (-)NCBI
mRatBN7.2975,871,841 - 75,885,801 (-)NCBI
Rnor_6.0981,569,289 - 81,582,650 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083668   ⟹   XP_038939596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,334,922 (-)NCBI
mRatBN7.2975,871,841 - 75,885,802 (-)NCBI
RefSeq Acc Id: XM_039083669   ⟹   XP_038939597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,338,469 (-)NCBI
mRatBN7.2975,871,841 - 75,888,658 (-)NCBI
RefSeq Acc Id: XM_039083670   ⟹   XP_038939598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8983,320,974 - 83,329,513 (-)NCBI
mRatBN7.2975,871,835 - 75,889,366 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001007714   ⟸   NM_001007713
- UniProtKB: Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451967   ⟸   XM_017596478
- Peptide Label: isoform X1
- UniProtKB: Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451968   ⟸   XM_017596479
- Peptide Label: isoform X1
- UniProtKB: Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451966   ⟸   XM_017596477
- Peptide Label: isoform X1
- UniProtKB: Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072508   ⟸   ENSRNOT00000089985
RefSeq Acc Id: ENSRNOP00000073792   ⟸   ENSRNOT00000089952
RefSeq Acc Id: ENSRNOP00000019848   ⟸   ENSRNOT00000019848
RefSeq Acc Id: XP_038939598   ⟸   XM_039083670
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939597   ⟸   XM_039083669
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939596   ⟸   XM_039083668
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6F5 (UniProtKB/TrEMBL),   A0A9K3Y6R8 (UniProtKB/TrEMBL),   Q6AYE0 (UniProtKB/TrEMBL),   A0A0G2K356 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYE0-F1-model_v2 AlphaFold Q6AYE0 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696752
Promoter ID:EPDNEW_R7271
Type:multiple initiation site
Name:Tmbim1_2
Description:transmembrane BAX inhibitor motif containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7272  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0981,579,791 - 81,579,851EPDNEW
RGD ID:13696747
Promoter ID:EPDNEW_R7272
Type:multiple initiation site
Name:Tmbim1_1
Description:transmembrane BAX inhibitor motif containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7271  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0981,586,513 - 81,586,573EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359409 AgrOrtholog
BioCyc Gene G2FUF-27141 BioCyc
Ensembl Genes ENSRNOG00000014797 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019848.6 UniProtKB/TrEMBL
  ENSRNOT00000089952 ENTREZGENE
  ENSRNOT00000089952.2 UniProtKB/TrEMBL
  ENSRNOT00000089985.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7123233 IMAGE-MGC_LOAD
InterPro Bax_inhibitor-1-related UniProtKB/TrEMBL
KEGG Report rno:316516 UniProtKB/TrEMBL
MGC_CLONE MGC:94053 IMAGE-MGC_LOAD
NCBI Gene 316516 ENTREZGENE
PANTHER PROTEIN LIFEGUARD 3 UniProtKB/TrEMBL
  UPF0005 UniProtKB/TrEMBL
Pfam Bax1-I UniProtKB/TrEMBL
PhenoGen Tmbim1 PhenoGen
RatGTEx ENSRNOG00000014797 RatGTEx
UniProt A0A0G2K356 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K6F5 ENTREZGENE
  A0A9K3Y6R8 ENTREZGENE, UniProtKB/TrEMBL
  A6JVT9_RAT UniProtKB/TrEMBL
  F7FKW1_RAT UniProtKB/TrEMBL
  Q6AYE0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2K6F5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Tmbim1  transmembrane BAX inhibitor motif containing 1  MGC94053  similar to RECS1  Symbol and Name updated 1299863 APPROVED
2005-07-29 MGC94053  similar to RECS1      Symbol and Name status set to provisional 70820 PROVISIONAL