Maf1 (MAF1 homolog, negative regulator of RNA polymerase III) - Rat Genome Database

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Gene: Maf1 (MAF1 homolog, negative regulator of RNA polymerase III) Rattus norvegicus
Analyze
Symbol: Maf1
Name: MAF1 homolog, negative regulator of RNA polymerase III
RGD ID: 1359315
Description: Enables GABA receptor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase I and negative regulation of transcription by RNA polymerase III. Located in several cellular components, including dendrite; inhibitory synapse; and perinuclear region of cytoplasm. Orthologous to human MAF1 (MAF1 homolog, negative regulator of RNA polymerase III); PARTICIPATES IN RNA polymerase III transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC315093; MAF1 homolog; MAF1 homolog (S. cerevisiae); MAF1 negative regulator of RNA polymerase III; repressor of RNA polymerase III transcription MAF1 homolog; similar to homolog of yeast MAF1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,955,876 - 109,958,909 (+)NCBIGRCr8
mRatBN7.27108,075,173 - 108,078,252 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,075,189 - 108,078,249 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,818,866 - 109,821,899 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,042,560 - 112,045,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,001,012 - 112,004,045 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,417,643 - 117,420,722 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,417,687 - 117,420,719 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,405,273 - 117,408,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,402,298 - 114,405,331 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,436,527 - 114,439,560 (+)NCBI
Celera7104,427,544 - 104,430,577 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IDA)
cytoplasm  (ISO,ISS)
cytosol  (IDA,IEA,ISO)
dendrite  (IDA)
inhibitory synapse  (IDA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,IEA,ISO,ISS)
perinuclear region of cytoplasm  (IDA)
plasma membrane  (IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of pol III transcription by nutrient and stress signaling pathways. Moir RD and Willis IM, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):361-75. doi: 10.1016/j.bbagrm.2012.11.001. Epub 2012 Nov 16.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
5. Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons. Smith KR, etal., Mol Cell Neurosci. 2010 Aug;44(4):330-41. doi: 10.1016/j.mcn.2010.04.004. Epub 2010 Apr 22.
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Vannini A Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):258-64. doi: 10.1016/j.bbagrm.2012.09.009. Epub 2012 Sep 29.
Additional References at PubMed
PMID:17499043   PMID:18377933   PMID:20233713   PMID:20543138   PMID:25943107  


Genomics

Comparative Map Data
Maf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,955,876 - 109,958,909 (+)NCBIGRCr8
mRatBN7.27108,075,173 - 108,078,252 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,075,189 - 108,078,249 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,818,866 - 109,821,899 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,042,560 - 112,045,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,001,012 - 112,004,045 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,417,643 - 117,420,722 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,417,687 - 117,420,719 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,405,273 - 117,408,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,402,298 - 114,405,331 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,436,527 - 114,439,560 (+)NCBI
Celera7104,427,544 - 104,430,577 (+)NCBICelera
Cytogenetic Map7q34NCBI
MAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,104,461 - 144,107,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,104,461 - 144,107,611 (+)EnsemblGRCh38hg38GRCh38
GRCh378145,159,364 - 145,162,514 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,231,293 - 145,234,503 (+)NCBINCBI36Build 36hg18NCBI36
Celera8141,496,826 - 141,500,038 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,435,186 - 140,438,398 (+)NCBIHuRef
CHM1_18145,199,686 - 145,202,898 (+)NCBICHM1_1
T2T-CHM13v2.08145,265,255 - 145,268,407 (+)NCBIT2T-CHM13v2.0
Maf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,235,494 - 76,238,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,235,494 - 76,238,580 (+)EnsemblGRCm39 Ensembl
GRCm381576,351,294 - 76,354,378 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,351,294 - 76,354,380 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,181,724 - 76,184,808 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,178,561 - 76,181,628 (+)NCBIMGSCv36mm8
Celera1577,851,355 - 77,854,439 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.75NCBI
Maf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,765,966 - 2,769,260 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,765,966 - 2,769,260 (+)NCBIChiLan1.0ChiLan1.0
MAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,593,184 - 161,597,214 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,124,200 - 137,127,095 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,870,815 - 140,873,947 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,862,698 - 143,865,895 (+)NCBIpanpan1.1PanPan1.1panPan2
MAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,598,819 - 37,601,713 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,598,600 - 37,601,591 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,562,494 - 37,565,407 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,075,024 - 38,077,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,074,833 - 38,077,937 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,747,082 - 37,749,995 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,875,762 - 37,878,675 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,351,941 - 38,354,854 (+)NCBIUU_Cfam_GSD_1.0
Maf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303647,129 - 650,193 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,072,606 - 8,076,338 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,073,228 - 8,076,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4597,472 - 600,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14597,410 - 600,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24750,540 - 753,648 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,315,739 - 138,318,963 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,316,980 - 138,319,456 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,552,912 - 1,556,082 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Maf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,714,959 - 12,718,361 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,715,888 - 12,719,058 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Maf1
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:79
Count of miRNA genes:58
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000018240
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat

Markers in Region
Maf  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,077,260 - 108,077,495 (+)MAPPERmRatBN7.2
Rnor_6.07117,419,731 - 117,419,965NCBIRnor6.0
Rnor_5.07117,407,361 - 117,407,595UniSTSRnor5.0
Celera7104,429,588 - 104,429,822UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000018240   ⟹   ENSRNOP00000018240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,075,189 - 108,078,247 (+)Ensembl
Rnor_6.0 Ensembl7117,417,687 - 117,420,719 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098036   ⟹   ENSRNOP00000089214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,075,322 - 108,078,249 (+)Ensembl
RefSeq Acc Id: NM_001014085   ⟹   NP_001014107
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,955,876 - 109,958,909 (+)NCBI
mRatBN7.27108,075,217 - 108,078,250 (+)NCBI
Rnor_6.07117,417,687 - 117,420,720 (+)NCBI
Rnor_5.07117,405,273 - 117,408,352 (+)NCBI
RGSC_v3.47114,402,298 - 114,405,331 (+)RGD
Celera7104,427,544 - 104,430,577 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241811   ⟹   XP_006241873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
mRatBN7.27108,075,174 - 108,078,252 (+)NCBI
Rnor_6.07117,417,643 - 117,420,722 (+)NCBI
Rnor_5.07117,405,273 - 117,408,352 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241812   ⟹   XP_006241874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
mRatBN7.27108,075,173 - 108,078,252 (+)NCBI
Rnor_6.07117,417,643 - 117,420,722 (+)NCBI
Rnor_5.07117,405,273 - 117,408,352 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079243   ⟹   XP_038935171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
mRatBN7.27108,075,173 - 108,078,252 (+)NCBI
RefSeq Acc Id: XM_063263593   ⟹   XP_063119663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
RefSeq Acc Id: XM_063263594   ⟹   XP_063119664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
RefSeq Acc Id: XM_063263595   ⟹   XP_063119665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
RefSeq Acc Id: XM_063263596   ⟹   XP_063119666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87109,956,036 - 109,958,909 (+)NCBI
RefSeq Acc Id: NP_001014107   ⟸   NM_001014085
- UniProtKB: Q5XIH0 (UniProtKB/Swiss-Prot),   A6HS93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241873   ⟸   XM_006241811
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006241874   ⟸   XM_006241812
- Peptide Label: isoform X6
- UniProtKB: A0A8L2Q923 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018240   ⟸   ENSRNOT00000018240
RefSeq Acc Id: XP_038935171   ⟸   XM_039079243
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000089214   ⟸   ENSRNOT00000098036
RefSeq Acc Id: XP_063119664   ⟸   XM_063263594
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063119665   ⟸   XM_063263595
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063119666   ⟸   XM_063263596
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063119663   ⟸   XM_063263593
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIH0-F1-model_v2 AlphaFold Q5XIH0 1-260 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695418
Promoter ID:EPDNEW_R5942
Type:initiation region
Name:Maf1_1
Description:MAF1 homolog, negative regulator of RNA polymerase III
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07117,417,657 - 117,417,717EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359315 AgrOrtholog
BioCyc Gene G2FUF-32935 BioCyc
Ensembl Genes ENSRNOG00000013514 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00065009879 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018240.6 UniProtKB/TrEMBL
  ENSRNOT00000098036.1 UniProtKB/TrEMBL
  ENSRNOT00065015884 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.1000.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7190634 IMAGE-MGC_LOAD
InterPro Maf1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Maf1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:315093 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94603 IMAGE-MGC_LOAD
NCBI Gene 315093 ENTREZGENE
PANTHER PTHR22504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Maf1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Maf1 PhenoGen
PIRSF RNA_polIII_Trep_MAF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013514 RatGTEx
  ENSRNOG00065009879 RatGTEx
UniProt A0A8I6AKG1_RAT UniProtKB/TrEMBL
  A0A8L2Q923 ENTREZGENE, UniProtKB/TrEMBL
  A6HS91_RAT UniProtKB/TrEMBL
  A6HS93 ENTREZGENE, UniProtKB/TrEMBL
  A6HS94_RAT UniProtKB/TrEMBL
  MAF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-09 Maf1  MAF1 homolog, negative regulator of RNA polymerase III  Maf1  MAF1 negative regulator of RNA polymerase III  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-01 Maf1  MAF1 negative regulator of RNA polymerase III  Maf1  MAF1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Maf1  MAF1 homolog (S. cerevisiae)  LOC315093  similar to homolog of yeast MAF1  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC315093  similar to homolog of yeast MAF1      Symbol and Name status set to provisional 70820 PROVISIONAL