Nutf2 (nuclear transport factor 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nutf2 (nuclear transport factor 2) Rattus norvegicus
Analyze
Symbol: Nutf2
Name: nuclear transport factor 2
RGD ID: 1359213
Description: Enables nuclear import signal receptor activity and small GTPase binding activity. Involved in negative regulation of vascular endothelial growth factor production; positive regulation of protein import into nucleus; and protein localization to nucleus. Located in cytosol and nuclear outer membrane. Part of nuclear pore central transport channel. Used to study diabetic retinopathy. Orthologous to human NUTF2 (nuclear transport factor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC72930; NTF-2; NTF2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Nutf2-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,662,168 - 50,683,457 (+)NCBIGRCr8
mRatBN7.21933,752,319 - 33,773,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,752,291 - 33,773,591 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,567,859 - 40,589,139 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,221,179 - 41,242,454 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,519,512 - 43,540,769 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,830,917 - 37,852,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,830,917 - 37,852,189 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,697,685 - 48,718,960 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,697,564 - 35,718,839 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,702,444 - 35,723,720 (+)NCBI
Celera1933,179,879 - 33,201,155 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP. Bayliss R, etal., J Mol Biol. 1999 Oct 29;293(3):579-93.
2. Separate binding sites on nuclear transport factor 2 (NTF2) for GDP-Ran and the phenylalanine-rich repeat regions of nucleoporins p62 and Nsp1p. Clarkson WD, etal., J Mol Biol. 1996 Nov 8;263(4):517-24.
3. Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran. Clarkson WD, etal., J Mol Biol. 1997 Oct 10;272(5):716-30.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. Hu T, etal., J Cell Biol 1996 Aug;134(3):589-601.
6. Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. Kent HM, etal., J Mol Biol. 1999 Jun 11;289(3):565-77.
7. Crystallization and preliminary X-ray diffraction analysis of nuclear transport factor 2. Kent HM, etal., J Struct Biol 1996 Mar-Apr;116(2):326-9.
8. Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy. Li B, etal., Mol Vis. 2009;15:861-9. Epub 2009 Apr 27.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import. Percipalle P, etal., J Mol Biol. 1997 Mar 7;266(4):722-32.
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. NTF2 mediates nuclear import of Ran. Ribbeck K, etal., EMBO J. 1998 Nov 16;17(22):6587-98.
14. Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran. Stewart M, etal., J Mol Biol. 1998 Apr 3;277(3):635-46.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7744965   PMID:8757804   PMID:10567585   PMID:10679025   PMID:15489334   PMID:15689618   PMID:16449645   PMID:18266911   PMID:19098896   PMID:20458337   PMID:22871113   PMID:23376485  
PMID:23533145   PMID:25416956  


Genomics

Comparative Map Data
Nutf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,662,168 - 50,683,457 (+)NCBIGRCr8
mRatBN7.21933,752,319 - 33,773,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,752,291 - 33,773,591 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,567,859 - 40,589,139 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,221,179 - 41,242,454 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,519,512 - 43,540,769 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,830,917 - 37,852,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,830,917 - 37,852,189 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,697,685 - 48,718,960 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,697,564 - 35,718,839 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,702,444 - 35,723,720 (+)NCBI
Celera1933,179,879 - 33,201,155 (+)NCBICelera
Cytogenetic Map19q12NCBI
NUTF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,846,933 - 67,872,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,846,882 - 67,872,567 (+)EnsemblGRCh38hg38GRCh38
GRCh371667,880,836 - 67,906,470 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,438,320 - 66,462,720 (+)NCBINCBI36Build 36hg18NCBI36
Build 341666,438,319 - 66,462,719NCBI
Celera1652,389,231 - 52,413,631 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,772,086 - 53,778,310 (+)NCBIHuRef
CHM1_11669,289,001 - 69,313,401 (+)NCBICHM1_1
T2T-CHM13v2.01673,642,707 - 73,668,340 (+)NCBIT2T-CHM13v2.0
Nutf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,587,165 - 106,607,034 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,587,212 - 106,605,962 (+)EnsemblGRCm39 Ensembl
GRCm388105,860,533 - 105,880,402 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1953,588,168 - 53,589,068 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,860,580 - 105,879,330 (+)EnsemblGRCm38mm10GRCm38
MGSCv378108,384,534 - 108,404,302 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,749,763 - 108,769,531 (+)NCBIMGSCv36mm8
Celera8110,088,387 - 110,108,163 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.05NCBI
Nutf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554848,832,871 - 8,854,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554848,832,871 - 8,854,151 (-)NCBIChiLan1.0ChiLan1.0
NUTF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,373,841 - 77,398,249 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,285,274 - 83,309,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,188,533 - 48,214,205 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,575,435 - 67,601,053 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,575,842 - 67,601,053 (+)Ensemblpanpan1.1panPan2
NUTF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,614,916 - 81,632,933 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,604,848 - 81,622,631 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,050,257 - 82,068,040 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,050,394 - 82,096,914 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,876,451 - 81,894,465 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,558,516 - 81,576,296 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,200,756 - 82,218,537 (-)NCBIUU_Cfam_GSD_1.0
Nutf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,356,708 - 41,374,581 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,214,267 - 18,232,442 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,214,593 - 18,232,406 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUTF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,469,505 - 28,489,005 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,469,274 - 28,489,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,643,308 - 25,663,373 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUTF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,567,429 - 59,592,725 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,566,171 - 59,592,843 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604722,291,136 - 22,318,807 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nutf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,504,303 - 18,524,957 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,505,935 - 18,525,335 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nutf2
89 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:695
Count of miRNA genes:278
Interacting mature miRNAs:345
Transcripts:ENSRNOT00000025608
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat

Markers in Region
AW546000  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2711,961,168 - 11,961,308 (+)MAPPERmRatBN7.2
mRatBN7.21531,592,096 - 31,592,236 (+)MAPPERmRatBN7.2
Rnor_6.01537,710,935 - 37,711,074NCBIRnor6.0
Rnor_6.0715,129,849 - 15,129,988NCBIRnor6.0
Rnor_5.01541,556,792 - 41,556,931UniSTSRnor5.0
Rnor_5.0715,288,979 - 15,289,118UniSTSRnor5.0
RGSC_v3.4713,539,988 - 13,540,127UniSTSRGSC3.4
RGSC_v3.41536,486,687 - 36,486,826UniSTSRGSC3.4
Celera1531,303,241 - 31,303,380UniSTS
Celera710,056,134 - 10,056,273UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map15p12UniSTS
Cytogenetic Map19q12UniSTS
RH139506  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,773,371 - 33,773,560 (+)MAPPERmRatBN7.2
Rnor_6.01937,851,969 - 37,852,157NCBIRnor6.0
Rnor_5.01948,718,737 - 48,718,925UniSTSRnor5.0
RGSC_v3.41935,718,616 - 35,718,804UniSTSRGSC3.4
Celera1933,200,932 - 33,201,120UniSTS
RH 3.4 Map19330.7UniSTS
Cytogenetic Map19q12UniSTS
UniSTS:235986  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,772,546 - 33,772,750 (+)MAPPERmRatBN7.2
Rnor_6.01937,851,144 - 37,851,347NCBIRnor6.0
Rnor_5.01948,717,912 - 48,718,115UniSTSRnor5.0
RGSC_v3.41935,717,791 - 35,717,994UniSTSRGSC3.4
Celera1933,200,107 - 33,200,310UniSTS
Cytogenetic Map19q12UniSTS
NUTF2_9060  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,772,023 - 33,772,523 (+)MAPPERmRatBN7.2
Rnor_6.01937,850,621 - 37,851,120NCBIRnor6.0
Rnor_5.01948,717,389 - 48,717,888UniSTSRnor5.0
RGSC_v3.41935,717,268 - 35,717,767UniSTSRGSC3.4
Celera1933,199,584 - 33,200,083UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000025608   ⟹   ENSRNOP00000025608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,752,291 - 33,773,591 (+)Ensembl
Rnor_6.0 Ensembl1937,830,917 - 37,852,189 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101055   ⟹   ENSRNOP00000080316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,752,312 - 33,772,516 (+)Ensembl
RefSeq Acc Id: NM_001007629   ⟹   NP_001007630
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,662,181 - 50,683,457 (+)NCBI
mRatBN7.21933,752,319 - 33,773,595 (+)NCBI
Rnor_6.01937,830,917 - 37,852,192 (+)NCBI
Rnor_5.01948,697,685 - 48,718,960 (+)NCBI
RGSC_v3.41935,697,564 - 35,718,839 (+)RGD
Celera1933,179,879 - 33,201,155 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255480   ⟹   XP_006255542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,662,168 - 50,683,457 (+)NCBI
mRatBN7.21933,752,487 - 33,773,595 (+)NCBI
Rnor_6.01937,831,294 - 37,852,192 (+)NCBI
Rnor_5.01948,697,685 - 48,718,960 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097624   ⟹   XP_038953552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,676,100 - 50,683,457 (+)NCBI
mRatBN7.21933,766,238 - 33,773,595 (+)NCBI
RefSeq Acc Id: XM_039097625   ⟹   XP_038953553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,672,149 - 50,683,457 (+)NCBI
mRatBN7.21933,762,287 - 33,773,595 (+)NCBI
RefSeq Acc Id: XM_039097626   ⟹   XP_038953554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,670,391 - 50,683,457 (+)NCBI
mRatBN7.21933,760,622 - 33,773,595 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001007630   ⟸   NM_001007629
- UniProtKB: P61972 (UniProtKB/Swiss-Prot),   A6IYT2 (UniProtKB/TrEMBL),   A0A8L2QDH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255542   ⟸   XM_006255480
- Peptide Label: isoform X1
- UniProtKB: P61972 (UniProtKB/Swiss-Prot),   A6IYT2 (UniProtKB/TrEMBL),   A0A8L2QDH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025608   ⟸   ENSRNOT00000025608
RefSeq Acc Id: XP_038953554   ⟸   XM_039097626
- Peptide Label: isoform X1
- UniProtKB: P61972 (UniProtKB/Swiss-Prot),   A6IYT2 (UniProtKB/TrEMBL),   A0A8L2QDH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953553   ⟸   XM_039097625
- Peptide Label: isoform X1
- UniProtKB: P61972 (UniProtKB/Swiss-Prot),   A6IYT2 (UniProtKB/TrEMBL),   A0A8L2QDH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953552   ⟸   XM_039097624
- Peptide Label: isoform X1
- UniProtKB: P61972 (UniProtKB/Swiss-Prot),   A6IYT2 (UniProtKB/TrEMBL),   A0A8L2QDH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080316   ⟸   ENSRNOT00000101055
Protein Domains
NTF2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61972-F1-model_v2 AlphaFold P61972 1-127 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701090
Promoter ID:EPDNEW_R11614
Type:multiple initiation site
Name:Nutf2_1
Description:nuclear transport factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,830,899 - 37,830,959EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359213 AgrOrtholog
BioCyc Gene G2FUF-5805 BioCyc
Ensembl Genes ENSRNOG00000018945 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055018000 UniProtKB/Swiss-Prot
  ENSRNOG00060011531 UniProtKB/Swiss-Prot
  ENSRNOG00065012523 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025608 ENTREZGENE
  ENSRNOT00000025608.5 UniProtKB/TrEMBL
  ENSRNOT00000101055 ENTREZGENE
  ENSRNOT00000101055.1 UniProtKB/Swiss-Prot
  ENSRNOT00055030499 UniProtKB/Swiss-Prot
  ENSRNOT00060019510 UniProtKB/Swiss-Prot
  ENSRNOT00065020371 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.450.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6886638 IMAGE-MGC_LOAD
InterPro NTF2 UniProtKB/Swiss-Prot
  NTF2-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2/Mtr2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTF2_dom UniProtKB/TrEMBL
  Nuclear_transport_factor_2_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291981 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72930 IMAGE-MGC_LOAD
NCBI Gene 291981 ENTREZGENE
PANTHER NUCLEAR TRANSPORT FACTOR 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12612 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NTF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nutf2 PhenoGen
PROSITE NTF2_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018945 RatGTEx
  ENSRNOG00055018000 RatGTEx
  ENSRNOG00060011531 RatGTEx
  ENSRNOG00065012523 RatGTEx
Superfamily-SCOP SSF54427 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QDH9 ENTREZGENE, UniProtKB/TrEMBL
  A6IYT2 ENTREZGENE, UniProtKB/TrEMBL
  NTF2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P13662 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Nutf2  nuclear transport factor 2  NTF2  nuclear transport factor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 NTF2  nuclear transport factor 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein may act as a dimer; crystal structure contains two polypeptide chains 1359758