Gpr180 (G protein-coupled receptor 180) - Rat Genome Database

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Gene: Gpr180 (G protein-coupled receptor 180) Rattus norvegicus
Analyze
Symbol: Gpr180
Name: G protein-coupled receptor 180
RGD ID: 1359193
Description: Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. Orthologous to human GPR180 (G protein-coupled receptor 180); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: integral membrane protein GPR180; intimal thickness-related receptor; MGC94555
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815101,602,870 - 101,635,556 (+)NCBIGRCr8
mRatBN7.21595,195,782 - 95,224,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1595,199,777 - 95,228,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1599,104,681 - 99,128,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015100,236,642 - 100,260,224 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01597,165,331 - 97,188,913 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015103,340,387 - 103,369,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15103,344,476 - 103,369,630 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015106,779,454 - 106,808,159 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415102,931,713 - 102,955,239 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115102,947,492 - 102,971,018 (+)NCBI
Celera1594,051,859 - 94,075,480 (+)NCBICelera
Cytogenetic Map15q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
4. Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor. Tsukada S, etal., Circulation 2003 Jan 21;107(2):313-9.
Additional References at PubMed
PMID:23376485  


Genomics

Comparative Map Data
Gpr180
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815101,602,870 - 101,635,556 (+)NCBIGRCr8
mRatBN7.21595,195,782 - 95,224,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1595,199,777 - 95,228,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1599,104,681 - 99,128,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015100,236,642 - 100,260,224 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01597,165,331 - 97,188,913 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015103,340,387 - 103,369,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15103,344,476 - 103,369,630 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015106,779,454 - 106,808,159 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415102,931,713 - 102,955,239 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115102,947,492 - 102,971,018 (+)NCBI
Celera1594,051,859 - 94,075,480 (+)NCBICelera
Cytogenetic Map15q24NCBI
GPR180
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381394,601,857 - 94,634,661 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1394,601,857 - 94,634,661 (+)EnsemblGRCh38hg38GRCh38
GRCh371395,254,111 - 95,286,915 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361394,052,105 - 94,079,947 (+)NCBINCBI36Build 36hg18NCBI36
Celera1376,102,074 - 76,129,910 (+)NCBICelera
Cytogenetic Map13q32.1NCBI
HuRef1375,851,373 - 75,884,161 (+)NCBIHuRef
CHM1_11395,223,550 - 95,256,344 (+)NCBICHM1_1
T2T-CHM13v2.01393,805,369 - 93,838,171 (+)NCBIT2T-CHM13v2.0
Gpr180
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914118,374,513 - 118,401,644 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14118,374,570 - 118,400,673 (+)EnsemblGRCm39 Ensembl
GRCm3814118,137,105 - 118,164,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14118,137,158 - 118,163,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714118,536,349 - 118,563,454 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614117,019,505 - 117,047,938 (+)NCBIMGSCv36mm8
Celera14116,691,545 - 116,719,686 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1461.78NCBI
Gpr180
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540415,250,532 - 15,275,392 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540415,250,532 - 15,275,381 (-)NCBIChiLan1.0ChiLan1.0
GPR180
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21496,130,516 - 96,193,324 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11394,799,189 - 94,832,461 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01375,774,879 - 75,808,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11394,930,657 - 94,964,493 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1394,930,349 - 94,957,032 (+)Ensemblpanpan1.1panPan2
GPR180
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12245,402,127 - 45,434,693 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2245,401,443 - 45,431,483 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2245,188,938 - 45,221,073 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02245,833,299 - 45,865,441 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2245,831,339 - 45,865,430 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12245,486,445 - 45,518,575 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02245,527,326 - 45,559,461 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02245,536,897 - 45,569,057 (+)NCBIUU_Cfam_GSD_1.0
Gpr180
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945180,962,446 - 180,990,884 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647214,959,862 - 14,989,709 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647214,963,022 - 14,989,709 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR180
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1163,720,095 - 63,751,684 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11163,720,048 - 63,764,720 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21169,826,935 - 69,859,762 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPR180
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1373,429,949 - 73,460,134 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl373,430,165 - 73,458,011 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604629,819,561 - 29,854,657 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr180
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248791,387,867 - 1,410,767 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248791,388,033 - 1,412,727 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gpr180
140 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:162
Interacting mature miRNAs:181
Transcripts:ENSRNOT00000013329
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat
1581519Cm59Cardiac mass QTL 592.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)158885347095840528Rat

Markers in Region
RH144142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21595,201,805 - 95,201,915 (+)MAPPERmRatBN7.2
Rnor_6.015103,346,554 - 103,346,663NCBIRnor6.0
Rnor_5.015106,785,080 - 106,785,189UniSTSRnor5.0
RGSC_v3.415102,933,687 - 102,933,796UniSTSRGSC3.4
Celera1594,053,843 - 94,053,952UniSTS
RH 3.4 Map15650.3UniSTS
Cytogenetic Map15q24UniSTS
BF397529  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21595,223,212 - 95,223,441 (+)MAPPERmRatBN7.2
Rnor_6.015103,367,891 - 103,368,119NCBIRnor6.0
Rnor_5.015106,806,417 - 106,806,645UniSTSRnor5.0
RGSC_v3.415102,955,095 - 102,955,323UniSTSRGSC3.4
Celera1594,075,336 - 94,075,564UniSTS
RH 3.4 Map15651.3UniSTS
Cytogenetic Map15q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 15 13 4 13 73 29 36 11
Low 15 42 28 15 28 8 11 1 6 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013329   ⟹   ENSRNOP00000013329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1595,199,782 - 95,223,355 (+)Ensembl
Rnor_6.0 Ensembl15103,344,476 - 103,368,035 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077047   ⟹   ENSRNOP00000068447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1595,199,777 - 95,228,373 (+)Ensembl
Rnor_6.0 Ensembl15103,344,501 - 103,358,080 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078103   ⟹   ENSRNOP00000069526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl15103,344,547 - 103,369,630 (+)Ensembl
RefSeq Acc Id: NM_001006994   ⟹   NP_001006995
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,931 - 101,632,118 (+)NCBI
mRatBN7.21595,199,770 - 95,224,955 (+)NCBI
Rnor_6.015103,344,476 - 103,368,035 (+)NCBI
Rnor_5.015106,779,454 - 106,808,159 (+)NCBI
RGSC_v3.415102,931,713 - 102,955,239 (+)RGD
Celera1594,051,859 - 94,075,480 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415002   ⟹   NP_001401931
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,931 - 101,632,118 (+)NCBI
mRatBN7.21595,199,770 - 95,224,955 (+)NCBI
RefSeq Acc Id: XM_006252455   ⟹   XP_006252517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,817 - 101,632,118 (+)NCBI
mRatBN7.21595,199,754 - 95,224,955 (+)NCBI
Rnor_6.015103,344,408 - 103,369,633 (+)NCBI
Rnor_5.015106,779,454 - 106,808,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599719   ⟹   XP_017455208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,602,870 - 101,632,118 (+)NCBI
mRatBN7.21595,195,782 - 95,222,884 (+)NCBI
Rnor_6.015103,340,387 - 103,367,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063274349   ⟹   XP_063130419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,811 - 101,635,556 (+)NCBI
RefSeq Acc Id: XM_063274350   ⟹   XP_063130420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,813 - 101,627,392 (+)NCBI
RefSeq Acc Id: XM_063274351   ⟹   XP_063130421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,606,811 - 101,627,392 (+)NCBI
RefSeq Acc Id: XM_063274352   ⟹   XP_063130422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815101,614,313 - 101,632,118 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001006995   ⟸   NM_001006994
- Peptide Label: isoform 1
- UniProtKB: G3V799 (UniProtKB/TrEMBL),   Q5XIJ2 (UniProtKB/TrEMBL),   A0A096MKB1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252517   ⟸   XM_006252455
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455208   ⟸   XM_017599719
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000068447   ⟸   ENSRNOT00000077047
RefSeq Acc Id: ENSRNOP00000069526   ⟸   ENSRNOT00000078103
RefSeq Acc Id: ENSRNOP00000013329   ⟸   ENSRNOT00000013329
RefSeq Acc Id: NP_001401931   ⟸   NM_001415002
- Peptide Label: isoform 2 precursor
- UniProtKB: A6HUG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130419   ⟸   XM_063274349
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130421   ⟸   XM_063274351
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063130420   ⟸   XM_063274350
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130422   ⟸   XM_063274352
- Peptide Label: isoform X6
Protein Domains
GPR180/TMEM145 transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V799-F1-model_v2 AlphaFold G3V799 1-339 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699872
Promoter ID:EPDNEW_R10395
Type:initiation region
Name:Gpr180_1
Description:G protein-coupled receptor 180
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.015103,344,430 - 103,344,490EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359193 AgrOrtholog
BioCyc Gene G2FUF-12451 BioCyc
Ensembl Genes ENSRNOG00000009766 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013329 ENTREZGENE
  ENSRNOT00000013329.8 UniProtKB/TrEMBL
  ENSRNOT00000077047.3 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7189368 IMAGE-MGC_LOAD
InterPro GPR180/TMEM145 UniProtKB/TrEMBL
  Rhodopsin-like_GPCR_TM_domain UniProtKB/TrEMBL
KEGG Report rno:306165 UniProtKB/TrEMBL
MGC_CLONE MGC:94555 IMAGE-MGC_LOAD
NCBI Gene 306165 ENTREZGENE
PANTHER INTEGRAL MEMBRANE PROTEIN GPR180 UniProtKB/TrEMBL
  INTIMAL THICKNESS RECEPTOR-RELATED UniProtKB/TrEMBL
Pfam GpcrRhopsn4 UniProtKB/TrEMBL
PhenoGen Gpr180 PhenoGen
RatGTEx ENSRNOG00000009766 RatGTEx
UniProt A0A096MKB1 ENTREZGENE, UniProtKB/TrEMBL
  A6HUG1 ENTREZGENE, UniProtKB/TrEMBL
  G3V799 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIJ2 ENTREZGENE
UniProt Secondary Q5XIJ2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Gpr180  G protein-coupled receptor 180  MGC94555  intimal thickness-related receptor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 MGC94555  intimal thickness-related receptor      Symbol and Name status set to provisional 70820 PROVISIONAL