(S)-nicotine decreases expression ISO Irf8 (Mus musculus) 6480464 Nicotine results in decreased expression of IRF8 mRNA CTD PMID:17456735 1,2-dimethylhydrazine increases expression ISO Irf8 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of IRF8 mRNA CTD PMID:22206623 17beta-estradiol affects expression ISO Irf8 (Mus musculus) 6480464 Estradiol affects the expression of IRF8 mRNA CTD PMID:15598610 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Irf8 (Mus musculus) 6480464 2 more ... CTD PMID:21851831 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Irf8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of IRF8 mRNA CTD PMID:21570461 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of IRF8 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IRF8 mRNA CTD PMID:32109520 and PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Irf8 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of IRF8 mRNA CTD PMID:21851831 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Irf8 (Mus musculus) 6480464 2 more ... CTD PMID:21851831 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of IRF8 mRNA CTD PMID:25380136 4-hydroxynon-2-enal decreases expression ISO Irf8 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of IRF8 mRNA CTD PMID:19191707 5-aza-2'-deoxycytidine multiple interactions ISO IRF8 (Homo sapiens) 329902079 5-aza-2'-deoxycytidine increases expression and decreases methylation of IRF8 in dendritic cells RGD 5-aza-2'-deoxycytidine multiple interactions ISO IRF8 (Homo sapiens) 329961558 5-aza-2'-deoxycytidine increases expression of IRF8 mRNA and decreases methylation of IRF8 DNA in dendritic cells RGD 5-aza-2'-deoxycytidine multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Decitabine affects the methylation of IRF8 promoter] which affects the expression of IRF8 protein and trichostatin A affects the reaction [[Decitabine affects the methylation of IRF8 promoter] which affects the expression of IRF8 protein] CTD PMID:18922617 8'-apo-beta,psi-caroten-8'-al increases expression ISO IRF8 (Homo sapiens) 6480464 apocarotenal results in increased expression of IRF8 mRNA CTD PMID:17034753 acetamide increases expression EXP 6480464 acetamide results in increased expression of IRF8 mRNA CTD PMID:31881176 aflatoxin B1 increases expression ISO IRF8 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of IRF8 mRNA CTD PMID:22100608 all-trans-retinoic acid multiple interactions ISO IRF8 (Homo sapiens) 6480464 STAT1 protein affects the reaction [Tretinoin results in increased expression of IRF8 protein] CTD PMID:16918696 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of IRF8 mRNA CTD PMID:30779732 antirheumatic drug decreases expression ISO IRF8 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of IRF8 mRNA CTD PMID:24449571 aripiprazole multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Aripiprazole co-treated with Ozone] results in decreased expression of IRF8 mRNA CTD PMID:31476115 arsane increases methylation ISO IRF8 (Homo sapiens) 6480464 Arsenic results in increased methylation of IRF8 gene CTD PMID:27838757 arsenic atom increases methylation ISO IRF8 (Homo sapiens) 6480464 Arsenic results in increased methylation of IRF8 gene CTD PMID:27838757 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of IRF8 gene CTD PMID:35440735 benzo[a]pyrene decreases expression ISO Irf8 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of IRF8 mRNA CTD PMID:21569818 benzo[a]pyrene increases expression ISO IRF8 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of IRF8 mRNA CTD PMID:32234424 benzo[a]pyrene decreases expression ISO IRF8 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of IRF8 mRNA CTD PMID:30453624 benzo[a]pyrene increases methylation ISO IRF8 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of IRF8 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO IRF8 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of IRF8 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO Irf8 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of IRF8 mRNA CTD PMID:22228805 benzoates decreases expression ISO IRF8 (Homo sapiens) 6480464 Benzoates analog results in decreased expression of IRF8 mRNA CTD PMID:29472718 beta-carotene increases expression ISO IRF8 (Homo sapiens) 6480464 beta Carotene results in increased expression of IRF8 mRNA CTD PMID:17034753 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of IRF8 mRNA CTD PMID:25181051 and PMID:34947998 bisphenol A decreases methylation ISO IRF8 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of IRF8 gene CTD PMID:31601247 buta-1,3-diene decreases expression ISO Irf8 (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of IRF8 mRNA CTD PMID:29038090 butanal increases expression ISO IRF8 (Homo sapiens) 6480464 butyraldehyde results in increased expression of IRF8 mRNA CTD PMID:26079696 Calcimycin multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA and fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] CTD PMID:21331654 carbon monoxide decreases activity ISO Irf8 (Mus musculus) 6480464 Carbon Monoxide results in decreased activity of IRF8 protein CTD PMID:16365149 carbon nanotube decreases expression ISO Irf8 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO IRF8 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to IRF8 gene] CTD PMID:28238834 chloroprene decreases expression ISO Irf8 (Mus musculus) 6480464 Chloroprene results in decreased expression of IRF8 mRNA CTD PMID:23125180 choline multiple interactions ISO Irf8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IRF8 mRNA CTD PMID:20938992 copper atom multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 copper(0) multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 crocidolite asbestos decreases expression ISO IRF8 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of IRF8 mRNA CTD PMID:24160326 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of IRF8 mRNA CTD PMID:27523638 cyclosporin A decreases expression ISO IRF8 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of IRF8 mRNA CTD PMID:27989131 cyclosporin A multiple interactions ISO IRF8 (Homo sapiens) 329961558 cyclosporin A increases expression of IRF8 mRNA and decreases methylation of IRF8 in dendritic cells RGD dexamethasone multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Dexamethasone results in increased phosphorylation of and results in increased activity of NR3C1 protein] which results in increased expression of IRF8 mRNA CTD PMID:18483179 dexamethasone decreases methylation ISO IRF8 (Homo sapiens) 329961558 dexamethasone decreases methylation of IRF8 DNA in dendritic cells RGD dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IRF8 mRNA CTD PMID:21266533 disulfiram multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 ethanol multiple interactions ISO Irf8 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of IRF8 mRNA CTD PMID:30517762 ethanol increases expression ISO Irf8 (Mus musculus) 6480464 Ethanol results in increased expression of IRF8 mRNA CTD PMID:30319688 fenfluramine increases expression ISO IRF8 (Homo sapiens) 6480464 Fenfluramine results in increased expression of IRF8 mRNA CTD PMID:22140631 folic acid multiple interactions ISO Irf8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IRF8 mRNA CTD PMID:20938992 fonofos increases methylation ISO IRF8 (Homo sapiens) 6480464 Fonofos results in increased methylation of IRF8 promoter CTD PMID:22847954 Fulvic acid multiple interactions ISO IRF8 (Homo sapiens) 6480464 fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] CTD PMID:21331654 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of IRF8 mRNA CTD PMID:22061828 and PMID:33387578 iron atom decreases expression ISO IRF8 (Homo sapiens) 6480464 Iron deficiency results in decreased expression of IRF8 mRNA CTD PMID:20368581 iron(0) decreases expression ISO IRF8 (Homo sapiens) 6480464 Iron deficiency results in decreased expression of IRF8 mRNA CTD PMID:20368581 L-methionine multiple interactions ISO Irf8 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IRF8 mRNA CTD PMID:20938992 lead(0) increases expression ISO Irf8 (Mus musculus) 6480464 Lead results in increased expression of IRF8 protein CTD PMID:28973681 lead(0) increases expression ISO IRF8 (Homo sapiens) 6480464 Lead results in increased expression of IRF8 protein CTD PMID:28973681 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of IRF8 mRNA CTD PMID:35283115 lipopolysaccharide multiple interactions ISO Irf8 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [[Lipopolysaccharides co-treated with IL4 protein] results in increased expression of IRF8 protein] more ... CTD PMID:10415056 more ... lipopolysaccharide multiple interactions ISO IRF8 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of IRF8 mRNA CTD PMID:35811015 lipopolysaccharide increases expression ISO IRF8 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of IRF8 mRNA CTD PMID:35811015 lipopolysaccharide increases expression ISO Irf8 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of IRF8 mRNA CTD PMID:11123339 and PMID:26582142 mercury atom multiple interactions ISO Irf8 (Mus musculus) 6480464 [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA more ... CTD PMID:28453771 mercury dichloride multiple interactions ISO Irf8 (Mus musculus) 6480464 [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA more ... CTD PMID:28453771 mercury(0) multiple interactions ISO Irf8 (Mus musculus) 6480464 [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA more ... CTD PMID:28453771 MK-2206 decreases expression ISO IRF8 (Homo sapiens) 6480464 MK 2206 results in decreased expression of IRF8 protein CTD PMID:34398343 MK-2206 multiple interactions ISO IRF8 (Homo sapiens) 6480464 MK 2206 inhibits the reaction [RARRES2 protein results in increased expression of IRF8 protein] CTD PMID:34398343 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases degradation ISO Irf8 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of IRF8 protein CTD PMID:15837792 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of IRF8 mRNA CTD PMID:25380136 nickel atom increases expression ISO IRF8 (Homo sapiens) 6480464 Nickel results in increased expression of IRF8 mRNA CTD PMID:24768652 and PMID:25583101 nickel sulfate increases expression ISO IRF8 (Homo sapiens) 6480464 nickel sulfate results in increased expression of IRF8 mRNA CTD PMID:22714537 nicotine decreases expression ISO Irf8 (Mus musculus) 6480464 Nicotine results in decreased expression of IRF8 mRNA CTD PMID:17456735 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of IRF8 mRNA CTD PMID:25729387 ozone multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Aripiprazole co-treated with Ozone] results in decreased expression of IRF8 mRNA CTD PMID:31476115 ozone multiple interactions ISO Irf8 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of IRF8 mRNA CTD PMID:34911549 ozone decreases expression ISO IRF8 (Homo sapiens) 6480464 Ozone results in decreased expression of IRF8 mRNA CTD PMID:31476115 paclitaxel increases expression ISO Irf8 (Mus musculus) 6480464 Paclitaxel results in increased expression of IRF8 mRNA CTD PMID:11123339 paclitaxel multiple interactions EXP 6480464 1-((3-benzyl-3-methyl-2 more ... CTD PMID:30414958 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of IRF8 mRNA and Paclitaxel results in increased expression of IRF8 protein CTD PMID:30414958 paclitaxel multiple interactions ISO Irf8 (Mus musculus) 6480464 TLR4 protein affects the reaction [Paclitaxel results in increased expression of IRF8 mRNA] CTD PMID:11123339 paracetamol affects expression ISO Irf8 (Mus musculus) 6480464 Acetaminophen affects the expression of IRF8 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IRF8 mRNA CTD PMID:33387578 paracetamol increases expression ISO IRF8 (Homo sapiens) 6480464 Acetaminophen results in increased expression of IRF8 mRNA CTD PMID:26690555 and PMID:29067470 parathion increases methylation ISO IRF8 (Homo sapiens) 6480464 Parathion results in increased methylation of IRF8 promoter CTD PMID:22847954 pentanal increases expression ISO IRF8 (Homo sapiens) 6480464 pentanal results in increased expression of IRF8 mRNA CTD PMID:26079696 phorbol 13-acetate 12-myristate multiple interactions ISO IRF8 (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA and fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] CTD PMID:21331654 pirinixic acid decreases expression ISO Irf8 (Mus musculus) 6480464 pirinixic acid results in decreased expression of IRF8 mRNA CTD PMID:17426115 pirinixic acid multiple interactions ISO IRF8 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of IRF8 mRNA CTD PMID:19710929 protein kinase inhibitor multiple interactions ISO IRF8 (Homo sapiens) 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of IRF8 mRNA] CTD PMID:28003376 resveratrol multiple interactions ISO Irf8 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of IRF8 mRNA] CTD PMID:35156769 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO IRF8 (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of IRF8 mRNA CTD PMID:35811015 serpentine asbestos decreases expression ISO IRF8 (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased expression of IRF8 mRNA CTD PMID:24160326 sodium arsenite increases expression ISO IRF8 (Homo sapiens) 6480464 sodium arsenite results in increased expression of IRF8 mRNA CTD PMID:29301061 sulforaphane decreases expression ISO IRF8 (Homo sapiens) 6480464 sulforaphane results in decreased expression of IRF8 mRNA CTD PMID:26833863 terbufos increases methylation ISO IRF8 (Homo sapiens) 6480464 terbufos results in increased methylation of IRF8 promoter CTD PMID:22847954 testosterone decreases expression ISO IRF8 (Homo sapiens) 6480464 Testosterone results in decreased expression of IRF8 mRNA CTD PMID:33359661 tetrachloromethane increases expression ISO Irf8 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of IRF8 mRNA CTD PMID:27339419 tetrachloromethane multiple interactions ISO Irf8 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of IRF8 mRNA CTD PMID:30517762 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of IRF8 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO Irf8 (Mus musculus) 6480464 titanium dioxide results in decreased expression of IRF8 mRNA CTD PMID:27760801 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of IRF8 mRNA CTD PMID:25729387 trichostatin A multiple interactions ISO IRF8 (Homo sapiens) 6480464 trichostatin A affects the reaction [[decitabine affects the methylation of IRF8 promoter] which affects the expression of IRF8 protein] CTD PMID:18922617 triptonide increases expression ISO Irf8 (Mus musculus) 6480464 triptonide results in increased expression of IRF8 mRNA CTD PMID:33045310 tunicamycin increases expression ISO IRF8 (Homo sapiens) 6480464 Tunicamycin results in increased expression of IRF8 mRNA CTD PMID:33545341 valproic acid increases expression ISO IRF8 (Homo sapiens) 6480464 Valproic Acid results in increased expression of IRF8 mRNA CTD PMID:29154799 vancomycin decreases expression ISO Irf8 (Mus musculus) 6480464 Vancomycin results in decreased expression of IRF8 mRNA CTD PMID:18930951 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of IRF8 mRNA CTD PMID:23034163 zoledronic acid decreases expression ISO IRF8 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of IRF8 mRNA CTD PMID:24714768
