Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SERINC2 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SERINC2 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of SERINC2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SERINC2 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of SERINC2 mRNA | CTD | PMID:30723492 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SERINC2 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SERINC2 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Serinc2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SERINC2 mRNA | CTD | PMID:26377647 and PMID:28922406 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SERINC2 mRNA | CTD | PMID:20106945 and PMID:21632981 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERINC2 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SERINC2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SERINC2 mRNA | CTD | PMID:24780913 and PMID:25825206 | acrylamide | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SERINC2 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of SERINC2 mRNA | CTD | PMID:23630614 and PMID:25378103 | aflatoxin B1 | decreases methylation | ISO | SERINC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SERINC2 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of SERINC2 mRNA | CTD | PMID:20488242 | all-trans-retinoic acid | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SERINC2 mRNA | CTD | PMID:23724009 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of SERINC2 mRNA | CTD | PMID:30779732 | atrazine | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of SERINC2 mRNA | CTD | PMID:22378314 | azathioprine | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Azathioprine results in increased expression of SERINC2 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to SERINC2 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | affects methylation | ISO | SERINC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SERINC2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SERINC2 mRNA | CTD | PMID:22316170 | benzo[a]pyrene diol epoxide I | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of SERINC2 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SERINC2 mRNA] | CTD | PMID:19850644 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SERINC2 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SERINC2 mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SERINC2 gene | CTD | PMID:31601247 | bisphenol A | increases methylation | ISO | SERINC2 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of SERINC2 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SERINC2 mRNA | CTD | PMID:32145629 | bisphenol A | affects expression | ISO | SERINC2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of SERINC2 mRNA | CTD | PMID:30903817 | bisphenol A | decreases methylation | ISO | Serinc2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of SERINC2 promoter | CTD | PMID:27312807 | bisphenol F | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERINC2 mRNA | CTD | PMID:28628672 | butan-1-ol | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SERINC2 mRNA | CTD | PMID:29432896 | calcitriol | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SERINC2 mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SERINC2 mRNA | CTD | PMID:16002434 more ... | carbon nanotube | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chloropicrin | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of SERINC2 mRNA | CTD | PMID:26352163 and PMID:28476498 | chlorpyrifos | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SERINC2 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SERINC2 mRNA | CTD | PMID:27392435 | clofibrate | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Clofibrate results in increased expression of SERINC2 mRNA | CTD | PMID:23811191 more ... | copper(II) sulfate | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SERINC2 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SERINC2 mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SERINC2 mRNA | CTD | PMID:20106945 and PMID:25562108 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of SERINC2 mRNA | CTD | PMID:23640034 | dexamethasone | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERINC2 mRNA | CTD | PMID:28628672 | dichloroacetic acid | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of SERINC2 mRNA | CTD | PMID:28962523 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of SERINC2 mRNA | CTD | PMID:25152437 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of SERINC2 mRNA | CTD | PMID:29391264 | epoxiconazole | affects expression | ISO | Serinc2 (Mus musculus) | 6480464 | epoxiconazole affects the expression of SERINC2 mRNA | CTD | PMID:35436446 | ethanol | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SERINC2 mRNA | CTD | PMID:29432896 | fenthion | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Fenthion results in increased expression of SERINC2 mRNA | CTD | PMID:34813904 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SERINC2 mRNA | CTD | PMID:24793618 | folic acid | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of SERINC2 mRNA | CTD | PMID:21867686 | folic acid | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SERINC2 mRNA | CTD | PMID:22206623 | fulvestrant | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SERINC2 gene | CTD | PMID:31601247 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of SERINC2 mRNA | CTD | PMID:27387713 | glycine betaine | decreases expression | EXP | | 6480464 | Betaine results in decreased expression of SERINC2 mRNA | CTD | PMID:26391144 | indometacin | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERINC2 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SERINC2 mRNA | CTD | PMID:36331819 | methidathion | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | methidathion results in increased expression of SERINC2 mRNA | CTD | PMID:34813904 | Muraglitazar | decreases expression | EXP | | 6480464 | muraglitazar results in decreased expression of SERINC2 mRNA | CTD | PMID:21515302 | O-methyleugenol | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | methyleugenol results in increased expression of SERINC2 mRNA | CTD | PMID:32234424 | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of SERINC2 mRNA | CTD | PMID:23665939 | ozone | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SERINC2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SERINC2 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SERINC2 mRNA | CTD | PMID:33387578 | PCB138 | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pentachlorophenol | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of SERINC2 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SERINC2 mRNA more ... | CTD | PMID:36331819 | permethrin | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Permethrin results in increased expression of SERINC2 mRNA | CTD | PMID:30629241 | Phenelzine | decreases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Phenelzine results in decreased expression of SERINC2 mRNA | CTD | PMID:31249575 | phenobarbital | affects expression | ISO | Serinc2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SERINC2 mRNA | CTD | PMID:23091169 | pirinixic acid | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of SERINC2 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SERINC2 mRNA | CTD | PMID:18301758 more ... | propiconazole | decreases expression | ISO | Serinc2 (Mus musculus) | 6480464 | propiconazole results in decreased expression of SERINC2 mRNA | CTD | PMID:21278054 | quercetin | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of SERINC2 mRNA | CTD | PMID:21632981 | silicon dioxide | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SERINC2 mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of SERINC2 mRNA | CTD | PMID:34973136 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of SERINC2 mRNA | CTD | PMID:19281266 | succimer | multiple interactions | ISO | Serinc2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SERINC2 mRNA | CTD | PMID:21641980 | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of SERINC2 mRNA | CTD | PMID:21515302 | testosterone | multiple interactions | ISO | SERINC2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SERINC2 mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of SERINC2 mRNA | CTD | PMID:21592394 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SERINC2 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SERINC2 mRNA] | CTD | PMID:31150632 | thimerosal | decreases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of SERINC2 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SERINC2 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | ISO | SERINC2 (Homo sapiens) | 6480464 | titanium dioxide results in increased expression of SERINC2 mRNA | CTD | PMID:34973136 | trichloroethene | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of SERINC2 mRNA | CTD | PMID:25549359 | triptonide | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | triptonide results in increased expression of SERINC2 mRNA | CTD | PMID:33045310 | tris(2-butoxyethyl) phosphate | affects expression | ISO | SERINC2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of SERINC2 mRNA | CTD | PMID:29024780 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of SERINC2 mRNA | CTD | PMID:21515302 | valproic acid | affects expression | ISO | Serinc2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of SERINC2 mRNA | CTD | PMID:17292431 and PMID:17963808 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of SERINC2 mRNA | CTD | PMID:29427782 | valproic acid | increases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of SERINC2 mRNA | CTD | PMID:19136453 and PMID:21427059 | vancomycin | decreases expression | ISO | Serinc2 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of SERINC2 mRNA | CTD | PMID:18930951 | |