Predicted to enable several functions, including LIM domain binding activity; protein homodimerization activity; and transcription coactivator activity. Predicted to contribute to DNA binding activity. Predicted to be involved in several processes, including negative regulation of erythrocyte differentiation; positive regulation of hemoglobin biosynthetic process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cerebellar Purkinje cell differentiation; epithelial structure maintenance; and hair follicle development. Predicted to be located in cell leading edge. Predicted to be part of beta-catenin-TCF complex and chromatin. Predicted to be active in nucleus. Orthologous to human LDB1 (LIM domain binding 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LDB1 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LDB1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of LDB1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of LDB1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of LDB1 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of LDB1 mRNA
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of LDB1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of LDB1 mRNA