Predicted to enable several functions, including DNA binding activity; DNA helicase activity; and ion binding activity. Predicted to be involved in several processes, including DNA metabolic process; G-quadruplex DNA unwinding; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including T cell differentiation; positive regulation of T cell proliferation; and regulation of DNA recombination. Predicted to be located in cytosol; nucleus; and replication fork. Predicted to be part of RecQ family helicase-topoisomerase III complex. Predicted to be active in chromosome; cytoplasm; and nucleus. Predicted to colocalize with PML body and chromosome, telomeric region. Human ortholog(s) of this gene implicated in Bloom syndrome. Orthologous to human BLM (BLM RecQ like helicase); PARTICIPATES IN DNA replication pathway; homologous recombination pathway of double-strand break repair; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid.
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of BLM mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of BLM mRNA
[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of BLM mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of BLM mRNA
fulvestrant inhibits the reaction [bisphenol A results in increased expression of BLM mRNA] and fulvestrant inhibits the reaction [Estradiol results in increased expression of BLM mRNA]
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of BLM mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of BLM mRNA