Hbs1l (HBS1-like translational GTPase) - Rat Genome Database

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Gene: Hbs1l (HBS1-like translational GTPase) Rattus norvegicus
Analyze
Symbol: Hbs1l
Name: HBS1-like translational GTPase
RGD ID: 1308509
Description: Predicted to enable GTPase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, no-go decay and rescue of stalled ribosome. Predicted to be located in cytoplasm. Predicted to be part of Dom34-Hbs1 complex. Predicted to be active in cytosolic ribosome. Human ortholog(s) of this gene implicated in beta thalassemia. Orthologous to human HBS1L (HBS1 like translational GTPase); PARTICIPATES IN translation termination pathway; mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Hbs1-like; Hbs1-like (S. cerevisiae); HBS1-like protein; LOC293408
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8117,912,139 - 17,989,651 (+)NCBIGRCr8
mRatBN7.2116,092,529 - 16,170,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,092,547 - 16,170,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,848,285 - 15,925,916 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,850,176 - 21,927,805 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,073,502 - 16,151,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,819,170 - 16,896,234 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,819,170 - 16,896,219 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,974,876 - 18,051,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,668,214 - 16,736,914 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1116,668,273 - 16,736,974 (+)NCBI
Celera114,510,728 - 14,588,123 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structural view on recycling of archaeal and eukaryotic ribosomes after canonical termination and ribosome rescue. Franckenberg S, etal., Curr Opin Struct Biol. 2012 Dec;22(6):786-96. doi: 10.1016/j.sbi.2012.08.002. Epub 2012 Sep 29.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Association of SNP in exon 1 of HBS1L with hemoglobin F level in beta0-thalassemia/hemoglobin E. Pandit RA, etal., Int J Hematol. 2008 Nov;88(4):357-61. doi: 10.1007/s12185-008-0167-3. Epub 2008 Oct 7.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:19056867   PMID:19946888  


Genomics

Comparative Map Data
Hbs1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8117,912,139 - 17,989,651 (+)NCBIGRCr8
mRatBN7.2116,092,529 - 16,170,082 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl116,092,547 - 16,170,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx115,848,285 - 15,925,916 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0121,850,176 - 21,927,805 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0116,073,502 - 16,151,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0116,819,170 - 16,896,234 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl116,819,170 - 16,896,219 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,974,876 - 18,051,510 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4116,668,214 - 16,736,914 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1116,668,273 - 16,736,974 (+)NCBI
Celera114,510,728 - 14,588,123 (+)NCBICelera
Cytogenetic Map1p12NCBI
HBS1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386134,960,378 - 135,054,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6134,960,378 - 135,103,056 (-)EnsemblGRCh38hg38GRCh38
GRCh376135,281,516 - 135,375,960 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366135,323,209 - 135,417,715 (-)NCBINCBI36Build 36hg18NCBI36
Build 346135,323,215 - 135,417,715NCBI
Celera6136,021,872 - 136,116,411 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6132,845,729 - 132,940,277 (-)NCBIHuRef
CHM1_16135,543,237 - 135,637,724 (-)NCBICHM1_1
T2T-CHM13v2.06136,148,628 - 136,243,073 (-)NCBIT2T-CHM13v2.0
Hbs1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391021,171,876 - 21,244,788 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1021,171,878 - 21,244,797 (+)EnsemblGRCm39 Ensembl
GRCm381021,295,979 - 21,368,889 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1021,295,979 - 21,368,898 (+)EnsemblGRCm38mm10GRCm38
MGSCv371021,015,785 - 21,088,695 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361020,996,767 - 21,058,314 (+)NCBIMGSCv36mm8
Celera1021,189,454 - 21,263,423 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map109.75NCBI
Hbs1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554391,683,685 - 1,762,314 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554391,684,466 - 1,762,314 (+)NCBIChiLan1.0ChiLan1.0
HBS1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25154,942,160 - 155,032,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16152,847,754 - 152,938,090 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06132,732,351 - 132,826,210 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16136,832,884 - 136,922,957 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6136,832,884 - 136,922,957 (-)Ensemblpanpan1.1panPan2
HBS1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1127,704,375 - 27,791,376 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl127,695,441 - 27,791,381 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,584,758 - 28,671,733 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0127,861,829 - 27,948,018 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl127,860,024 - 27,947,992 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1127,746,364 - 27,833,359 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0127,626,482 - 27,713,519 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0127,937,668 - 28,024,033 (-)NCBIUU_Cfam_GSD_1.0
Hbs1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946122,812,710 - 122,900,212 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365602,591,821 - 2,679,428 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365602,591,925 - 2,679,436 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HBS1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl129,018,351 - 29,052,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1128,968,778 - 29,052,427 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2132,459,545 - 32,530,004 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HBS1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11338,383,405 - 38,478,569 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1338,383,435 - 38,473,429 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604010,581,023 - 10,677,947 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hbs1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248862,605,364 - 2,691,705 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248862,606,072 - 2,691,323 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hbs1l
287 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:61
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000019734
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)11532110019121980Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat

Markers in Region
RH128240  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,169,677 - 16,169,884 (+)MAPPERmRatBN7.2
Rnor_6.0116,895,830 - 16,896,036NCBIRnor6.0
Rnor_5.0118,051,119 - 18,051,325UniSTSRnor5.0
RGSC_v3.4116,736,523 - 16,736,729UniSTSRGSC3.4
Celera114,587,732 - 14,587,938UniSTS
RH 3.4 Map1148.23UniSTS
Cytogenetic Map1p12UniSTS
RH130225  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,133,511 - 16,133,691 (+)MAPPERmRatBN7.2
Rnor_6.0116,859,959 - 16,860,138NCBIRnor6.0
Rnor_5.0118,015,248 - 18,015,427UniSTSRnor5.0
RGSC_v3.4116,699,379 - 16,699,558UniSTSRGSC3.4
Celera114,551,524 - 14,551,703UniSTS
RH 3.4 Map1148.63UniSTS
Cytogenetic Map1p12UniSTS
PMC140821P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,104,739 - 16,104,908 (+)MAPPERmRatBN7.2
Rnor_6.0116,830,491 - 16,830,659NCBIRnor6.0
Rnor_5.0117,986,628 - 17,986,796UniSTSRnor5.0
RGSC_v3.4116,671,140 - 16,671,308UniSTSRGSC3.4
Celera114,522,852 - 14,523,020UniSTS
Cytogenetic Map1p12UniSTS
BF390872  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,105,028 - 16,105,188 (+)MAPPERmRatBN7.2
Rnor_6.0116,830,780 - 16,830,939NCBIRnor6.0
Rnor_5.0117,986,917 - 17,987,076UniSTSRnor5.0
RGSC_v3.4116,671,429 - 16,671,588UniSTSRGSC3.4
Celera114,523,141 - 14,523,300UniSTS
RH 3.4 Map1163.6UniSTS
Cytogenetic Map1p12UniSTS
PMC140821P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2116,168,810 - 16,168,942 (+)MAPPERmRatBN7.2
Rnor_6.0116,894,963 - 16,895,094NCBIRnor6.0
Rnor_5.0118,050,252 - 18,050,383UniSTSRnor5.0
RGSC_v3.4116,735,656 - 16,735,787UniSTSRGSC3.4
Celera114,586,865 - 14,586,996UniSTS
Cytogenetic Map1p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000019734   ⟹   ENSRNOP00000019734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,092,574 - 16,170,067 (+)Ensembl
Rnor_6.0 Ensembl116,819,170 - 16,896,219 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086756   ⟹   ENSRNOP00000072325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,104,079 - 16,169,067 (+)Ensembl
Rnor_6.0 Ensembl116,819,249 - 16,895,650 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096492   ⟹   ENSRNOP00000091699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,092,566 - 16,170,067 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113225   ⟹   ENSRNOP00000086834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,092,588 - 16,170,074 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114016   ⟹   ENSRNOP00000086972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,092,547 - 16,108,201 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116762   ⟹   ENSRNOP00000095992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl116,092,547 - 16,127,931 (+)Ensembl
RefSeq Acc Id: NM_001011934   ⟹   NP_001011934
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,151 - 17,989,638 (+)NCBI
mRatBN7.2116,092,607 - 16,170,069 (+)NCBI
Rnor_6.0116,819,170 - 16,896,221 (+)NCBI
Rnor_5.0117,974,876 - 18,051,510 (+)NCBI
RGSC_v3.4116,668,214 - 16,736,914 (+)RGD
Celera114,510,728 - 14,588,123 (+)RGD
Sequence:
RefSeq Acc Id: XM_039106903   ⟹   XP_038962831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,139 - 17,989,651 (+)NCBI
mRatBN7.2116,092,529 - 16,170,082 (+)NCBI
RefSeq Acc Id: XM_039106909   ⟹   XP_038962837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,139 - 17,989,651 (+)NCBI
mRatBN7.2116,092,529 - 16,170,082 (+)NCBI
RefSeq Acc Id: XM_039106912   ⟹   XP_038962840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,139 - 17,930,006 (+)NCBI
mRatBN7.2116,092,529 - 16,110,719 (+)NCBI
RefSeq Acc Id: XM_063285773   ⟹   XP_063141843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,139 - 17,989,651 (+)NCBI
RefSeq Acc Id: XM_063285777   ⟹   XP_063141847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,912,139 - 17,989,651 (+)NCBI
RefSeq Acc Id: XM_063285786   ⟹   XP_063141856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,924,746 - 17,989,651 (+)NCBI
RefSeq Acc Id: XM_063285789   ⟹   XP_063141859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8117,925,782 - 17,989,651 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001011934   ⟸   NM_001011934
- UniProtKB: Q6AXM7 (UniProtKB/Swiss-Prot),   A0A8I6AGM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019734   ⟸   ENSRNOT00000019734
RefSeq Acc Id: ENSRNOP00000072325   ⟸   ENSRNOT00000086756
RefSeq Acc Id: XP_038962831   ⟸   XM_039106903
- Peptide Label: isoform X2
- UniProtKB: A6JPD9 (UniProtKB/TrEMBL),   A0A8I6AGM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962837   ⟸   XM_039106909
- Peptide Label: isoform X4
- UniProtKB: A0A8I6GEG8 (UniProtKB/TrEMBL),   A0A8I6AGM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962840   ⟸   XM_039106912
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GEM5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000086972   ⟸   ENSRNOT00000114016
RefSeq Acc Id: ENSRNOP00000086834   ⟸   ENSRNOT00000113225
RefSeq Acc Id: ENSRNOP00000091699   ⟸   ENSRNOT00000096492
RefSeq Acc Id: ENSRNOP00000095992   ⟸   ENSRNOT00000116762
RefSeq Acc Id: XP_063141843   ⟸   XM_063285773
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063141847   ⟸   XM_063285777
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063141856   ⟸   XM_063285786
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063141859   ⟸   XM_063285789
- Peptide Label: isoform X6
Protein Domains
HBS1-like protein N-terminal   tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXM7-F1-model_v2 AlphaFold Q6AXM7 1-679 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689516
Promoter ID:EPDNEW_R41
Type:multiple initiation site
Name:Hbs1l_1
Description:HBS1-like translational GTPase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0116,819,129 - 16,819,189EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308509 AgrOrtholog
BioCyc Gene G2FUF-62182 BioCyc
Ensembl Genes ENSRNOG00000014531 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019734 ENTREZGENE
  ENSRNOT00000019734.8 UniProtKB/Swiss-Prot
  ENSRNOT00000086756.2 UniProtKB/TrEMBL
  ENSRNOT00000096492.1 UniProtKB/TrEMBL
  ENSRNOT00000113225.1 UniProtKB/TrEMBL
  ENSRNOT00000114016.1 UniProtKB/TrEMBL
  ENSRNOT00000116762.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122195 IMAGE-MGC_LOAD
InterPro EFTu-like_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HBS1-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HBS1-like_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EF1A/Init_IF2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EFTu/EF1A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:293408 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95018 IMAGE-MGC_LOAD
NCBI Gene 293408 ENTREZGENE
PANTHER HBS1-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSLATION FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GTP_EFTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HBS1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hbs1l PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_TR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014531 RatGTEx
Superfamily-SCOP SSF109732 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50465 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K2P6_RAT UniProtKB/TrEMBL
  A0A8I6AGM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GEG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GEM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLW0_RAT UniProtKB/TrEMBL
  A6JPD9 ENTREZGENE, UniProtKB/TrEMBL
  A6JPE2_RAT UniProtKB/TrEMBL
  HBS1L_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-07 Hbs1l  HBS1-like translational GTPase  Hbs1l  Hbs1-like (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Hbs1l  Hbs1-like (S. cerevisiae)  Hbs1l_predicted  Hbs1-like (S. cerevisiae) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Hbs1l_predicted  Hbs1-like (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED