Fcho1 (FCH and mu domain containing endocytic adaptor 1) - Rat Genome Database

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Gene: Fcho1 (FCH and mu domain containing endocytic adaptor 1) Rattus norvegicus
Analyze
Symbol: Fcho1
Name: FCH and mu domain containing endocytic adaptor 1
RGD ID: 1307683
Description: Predicted to enable AP-2 adaptor complex binding activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; clathrin coat assembly; and clathrin-dependent endocytosis. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in clathrin-coated pit. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human FCHO1 (FCH and mu domain containing endocytic adaptor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: F-BAR domain only protein 1; FCH domain only 1; FCH domain only protein 1; LOC290639
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,447,424 - 18,464,738 (-)NCBIGRCr8
mRatBN7.21618,413,452 - 18,430,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,413,363 - 18,435,104 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,464,047 - 18,481,312 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,596,667 - 19,613,927 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,516,986 - 18,534,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,136,008 - 20,153,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,136,008 - 20,148,867 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,995,969 - 20,013,245 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,904,594 - 18,921,871 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,905,027 - 18,921,868 (-)NCBI
Celera1618,616,022 - 18,633,180 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses. Catsburg LA, etal., Elife. 2022 Jan 24;11:e74387. doi: 10.7554/eLife.74387.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20448150   PMID:22484487  


Genomics

Comparative Map Data
Fcho1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,447,424 - 18,464,738 (-)NCBIGRCr8
mRatBN7.21618,413,452 - 18,430,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,413,363 - 18,435,104 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,464,047 - 18,481,312 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,596,667 - 19,613,927 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,516,986 - 18,534,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,136,008 - 20,153,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,136,008 - 20,148,867 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,995,969 - 20,013,245 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,904,594 - 18,921,871 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,905,027 - 18,921,868 (-)NCBI
Celera1618,616,022 - 18,633,180 (-)NCBICelera
Cytogenetic Map16p14NCBI
FCHO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,747,744 - 17,788,561 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,747,718 - 17,788,568 (+)EnsemblGRCh38hg38GRCh38
GRCh371917,858,553 - 17,899,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,723,336 - 17,760,366 (+)NCBINCBI36Build 36hg18NCBI36
Build 341917,723,335 - 17,760,363NCBI
Celera1917,760,312 - 17,801,121 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,423,476 - 17,464,648 (+)NCBIHuRef
CHM1_11917,858,083 - 17,898,911 (+)NCBICHM1_1
T2T-CHM13v2.01917,881,862 - 17,922,647 (+)NCBIT2T-CHM13v2.0
Fcho1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,161,031 - 72,181,980 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,161,031 - 72,178,360 (-)EnsemblGRCm39 Ensembl
GRCm38871,708,387 - 71,729,330 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,708,387 - 71,725,716 (-)EnsemblGRCm38mm10GRCm38
MGSCv37874,232,286 - 74,249,580 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36874,637,635 - 74,654,635 (-)NCBIMGSCv36mm8
Celera874,222,813 - 74,240,091 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.43NCBI
Fcho1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,450,529 - 3,465,848 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,451,204 - 3,470,163 (-)NCBIChiLan1.0ChiLan1.0
FCHO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,612,753 - 22,654,045 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,619,943 - 21,660,849 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,230,202 - 17,271,133 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,206,424 - 18,245,987 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,213,869 - 18,245,725 (+)Ensemblpanpan1.1panPan2
FCHO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,106,982 - 45,131,173 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,106,983 - 45,134,325 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,019,095 - 45,046,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,592,304 - 45,619,706 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,592,304 - 45,619,686 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,828,688 - 44,855,626 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,238,727 - 45,266,142 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,514,775 - 45,541,666 (-)NCBIUU_Cfam_GSD_1.0
Fcho1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,685,464 - 203,716,345 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365963,252,826 - 3,265,359 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365963,234,603 - 3,265,484 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCHO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,958,134 - 59,990,490 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,958,122 - 59,990,511 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,527,564 - 59,559,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FCHO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,223,036 - 16,259,228 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,238,045 - 16,265,440 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,127,580 - 3,168,672 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcho1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,327,602 - 1,340,240 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,327,569 - 1,340,741 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fcho1
63 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:213
Count of miRNA genes:150
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000040464
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat

Markers in Region
BF399577  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,429,923 - 18,430,051 (+)MAPPERmRatBN7.2
Rnor_6.01620,152,480 - 20,152,607NCBIRnor6.0
Rnor_5.01620,012,441 - 20,012,568UniSTSRnor5.0
RGSC_v3.41618,921,067 - 18,921,194UniSTSRGSC3.4
Celera1618,632,482 - 18,632,609UniSTS
RH 3.4 Map16195.2UniSTS
Cytogenetic Map16p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 10 2 19 2 72 5
Low 1 12 38 30 30 1 1 2 24 36 11 1
Below cutoff 31 9 9 9 7 9 11 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001841533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005494564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040464   ⟹   ENSRNOP00000049715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,413,452 - 18,435,104 (-)Ensembl
Rnor_6.0 Ensembl1620,136,008 - 20,148,867 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111337   ⟹   ENSRNOP00000085471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,413,363 - 18,435,104 (-)Ensembl
RefSeq Acc Id: NM_001395712   ⟹   NP_001382641
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,424 - 18,464,698 (-)NCBI
mRatBN7.21618,413,452 - 18,430,726 (-)NCBI
RefSeq Acc Id: XM_006252864   ⟹   XP_006252926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,462,390 (-)NCBI
mRatBN7.21618,413,707 - 18,428,420 (-)NCBI
Rnor_6.01620,136,261 - 20,151,254 (-)NCBI
Rnor_5.01619,995,969 - 20,013,245 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252865   ⟹   XP_006252927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,462,390 (-)NCBI
mRatBN7.21618,413,707 - 18,428,420 (-)NCBI
Rnor_6.01620,136,261 - 20,151,254 (-)NCBI
Rnor_5.01619,995,969 - 20,013,245 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008771083   ⟹   XP_008769305
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,464,738 (-)NCBI
mRatBN7.21618,413,707 - 18,430,793 (-)NCBI
Rnor_6.01620,136,261 - 20,153,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600027   ⟹   XP_017455516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,464,738 (-)NCBI
mRatBN7.21618,413,707 - 18,430,795 (-)NCBI
Rnor_6.01620,136,261 - 20,153,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094302   ⟹   XP_038950230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,462,390 (-)NCBI
mRatBN7.21618,413,707 - 18,426,760 (-)NCBI
RefSeq Acc Id: XM_039094304   ⟹   XP_038950232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,449,121 - 18,460,735 (-)NCBI
mRatBN7.21618,415,145 - 18,426,762 (-)NCBI
RefSeq Acc Id: XM_039094305   ⟹   XP_038950233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,449,131 - 18,460,735 (-)NCBI
mRatBN7.21618,415,153 - 18,426,762 (-)NCBI
RefSeq Acc Id: XM_039094306   ⟹   XP_038950234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,454,893 (-)NCBI
mRatBN7.21618,413,707 - 18,422,302 (-)NCBI
RefSeq Acc Id: XM_039094307   ⟹   XP_038950235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,453,442 (-)NCBI
mRatBN7.21618,413,707 - 18,419,461 (-)NCBI
RefSeq Acc Id: XM_039094308   ⟹   XP_038950236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,454,088 (-)NCBI
mRatBN7.21618,413,707 - 18,420,121 (-)NCBI
RefSeq Acc Id: XM_039094309   ⟹   XP_038950237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,447,679 - 18,454,063 (-)NCBI
mRatBN7.21618,413,707 - 18,420,116 (-)NCBI
RefSeq Acc Id: XR_005494564
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,448,140 - 18,460,734 (-)NCBI
mRatBN7.21618,414,164 - 18,426,761 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_006252926   ⟸   XM_006252864
- Peptide Label: isoform X2
- UniProtKB: D3ZIM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252927   ⟸   XM_006252865
- Peptide Label: isoform X2
- UniProtKB: D3ZIM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769305   ⟸   XM_008771083
- Peptide Label: isoform X2
- UniProtKB: D3ZIM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455516   ⟸   XM_017600027
- Peptide Label: isoform X2
- UniProtKB: D3ZIM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000049715   ⟸   ENSRNOT00000040464
RefSeq Acc Id: XP_038950230   ⟸   XM_039094302
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950234   ⟸   XM_039094306
- Peptide Label: isoform X5
- UniProtKB: A6K9X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950236   ⟸   XM_039094308
- Peptide Label: isoform X7
- UniProtKB: A6K9X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950237   ⟸   XM_039094309
- Peptide Label: isoform X7
- UniProtKB: A6K9X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950235   ⟸   XM_039094307
- Peptide Label: isoform X6
- UniProtKB: A6K9X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950232   ⟸   XM_039094304
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950233   ⟸   XM_039094305
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000085471   ⟸   ENSRNOT00000111337
RefSeq Acc Id: NP_001382641   ⟸   NM_001395712
Protein Domains
F-BAR   MHD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIM5-F1-model_v2 AlphaFold D3ZIM5 1-560 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307683 AgrOrtholog
BioCyc Gene G2FUF-11824 BioCyc
Ensembl Genes ENSRNOG00000033912 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040464.5 UniProtKB/TrEMBL
  ENSRNOT00000111337.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  F_BAR UniProtKB/TrEMBL
  FCH_dom UniProtKB/TrEMBL
  MHD UniProtKB/TrEMBL
  SAFF_domain UniProtKB/TrEMBL
KEGG Report rno:290639 UniProtKB/TrEMBL
NCBI Gene 290639 ENTREZGENE
PANTHER PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  PTHR23065:SF6 UniProtKB/TrEMBL
Pfam FCH UniProtKB/TrEMBL
  SAFF UniProtKB/TrEMBL
PhenoGen Fcho1 PhenoGen
PROSITE F_BAR UniProtKB/TrEMBL
  MHD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033912 RatGTEx
SMART FCH UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
UniProt A0A8I6A3Y9_RAT UniProtKB/TrEMBL
  A6K9X9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIM5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Fcho1  FCH and mu domain containing endocytic adaptor 1  Fcho1  FCH domain only 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fcho1  FCH domain only 1   Fcho1_predicted  FCH domain only 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fcho1_predicted  FCH domain only 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED