Rftn2 (raftlin family member 2) - Rat Genome Database

Name: Rftn2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rftn2 (raftlin family member 2) Rattus norvegicus

Analyze

Symbol:

Rftn2

Name:

raftlin family member 2

RGD ID:

1307304

Description:

Predicted to act upstream of or within dsRNA transport and response to exogenous dsRNA. Predicted to be located in plasma membrane. Orthologous to human RFTN2 (raftlin family member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC363231; raftlin-2; RGD1307304; similar to 3222401M22Rik protein

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RFTN2 (raftlin family member 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rftn2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rftn2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RFTN2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RFTN2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rftn2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RFTN2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RFTN2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rftn2 (raftlin family member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RFTN2 (raftlin family member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rftn2 (raftlin family member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rftn2 (raftlin family member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	64,146,062 - 64,202,342 (-)	NCBI		GRCr8
mRatBN7.2	9	56,651,617 - 56,707,830 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	56,630,460 - 56,707,810 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	61,754,859 - 61,810,992 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	61,756,428 - 61,810,417 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	61,438,131 - 61,494,253 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	53,958,426 - 54,012,631 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	54,085,916 - 54,141,464 (-)	NCBI
Celera	9	54,133,122 - 54,189,029 (-)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3H-1,2-dithiole-3-thione (EXP)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

amitrole (EXP)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

clotrimazole (EXP)

copper atom (ISO)

copper(0) (ISO)

dioxygen (ISO)

disulfiram (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

FR900359 (ISO)

levonorgestrel (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

methimazole (EXP)

N-methyl-4-phenylpyridinium (EXP)

nickel atom (ISO)

ozone (ISO)

panobinostat (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

pirinixic acid (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

testosterone undecanoate (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

tungsten (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dsRNA transport (ISO)

response to exogenous dsRNA (ISO)

Cellular Component

plasma membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21266579

Genomics

Comparative Map Data

Rftn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	64,146,062 - 64,202,342 (-)	NCBI		GRCr8
mRatBN7.2	9	56,651,617 - 56,707,830 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	56,630,460 - 56,707,810 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	9	61,754,859 - 61,810,992 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	61,756,428 - 61,810,417 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	61,438,131 - 61,494,253 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	53,958,426 - 54,012,631 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	54,085,916 - 54,141,464 (-)	NCBI
Celera	9	54,133,122 - 54,189,029 (-)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

RFTN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	197,568,224 - 197,675,587 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	197,568,224 - 197,676,045 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	198,432,948 - 198,540,311 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	198,143,773 - 198,248,829 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	198,261,033 - 198,366,090	NCBI
Celera	2	192,191,399 - 192,296,503 (-)	NCBI		Celera
Cytogenetic Map	2	q33.1	NCBI
HuRef	2	190,287,828 - 190,392,953 (-)	NCBI		HuRef
CHM1_1	2	198,441,373 - 198,546,392 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	198,051,829 - 198,159,265 (-)	NCBI		T2T-CHM13v2.0

Rftn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	55,209,318 - 55,267,128 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	55,209,318 - 55,265,941 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	55,170,159 - 55,227,063 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	55,170,159 - 55,226,782 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	55,227,003 - 55,283,626 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	55,114,704 - 55,171,593 (-)	NCBI		MGSCv36	mm8
Celera	1	55,690,287 - 55,746,933 (-)	NCBI		Celera
Cytogenetic Map	1	C1.2	NCBI
cM Map	1	28.05	NCBI

Rftn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	2,983,270 - 3,030,643 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	2,982,753 - 3,030,594 (+)	NCBI	ChiLan1.0	ChiLan1.0

RFTN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	100,196,849 - 100,298,620 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	100,211,841 - 100,313,499 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	84,826,173 - 84,927,820 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	202,719,578 - 202,819,996 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	202,719,578 - 202,819,996 (-)	Ensembl	panpan1.1		panPan2

RFTN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	7,074,597 - 7,169,512 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	7,074,586 - 7,152,714 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	8,020,814 - 8,100,133 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	6,964,973 - 7,044,415 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	6,964,975 - 7,030,868 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	6,963,590 - 7,042,959 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	6,930,077 - 7,009,755 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	6,953,877 - 7,033,880 (-)	NCBI		UU_Cfam_GSD_1.0

Rftn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	155,216,284 - 155,281,489 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	1,561,801 - 1,621,789 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936506	1,561,910 - 1,620,476 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RFTN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	101,433,845 - 101,500,880 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	101,433,839 - 101,500,926 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	112,604,324 - 112,613,654 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RFTN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	83,082,681 - 83,168,828 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	83,079,215 - 83,168,814 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	116,280,880 - 116,363,395 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rftn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624889	2,644,622 - 2,699,245 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624889	2,632,246 - 2,700,356 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rftn2
189 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	84
Count of miRNA genes:	74
Interacting mature miRNAs:	77
Transcripts:	ENSRNOT00000020910, ENSRNOT00000058841
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	23754024	58157242	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	23754024	61381613	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	27468639	72468639	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
1598849	Memor17	Memory QTL 17	2.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	49968546	71098346	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	56627713	78595166	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat

Markers in Region

RH128200

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,653,195 - 56,653,345 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,756,391 - 61,756,540	NCBI	Rnor6.0
Rnor_5.0	9	61,439,668 - 61,439,817	UniSTS	Rnor5.0
RGSC_v3.4	9	53,958,604 - 53,958,753	UniSTS	RGSC3.4
Celera	9	54,134,654 - 54,134,803	UniSTS
RH 3.4 Map	9	479.57	UniSTS
Cytogenetic Map	9	q31	UniSTS

BE115627

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	56,706,651 - 56,706,810 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	61,809,842 - 61,810,000	NCBI	Rnor6.0
Rnor_5.0	9	61,493,119 - 61,493,277	UniSTS	Rnor5.0
RGSC_v3.4	9	54,012,056 - 54,012,214	UniSTS	RGSC3.4
Celera	9	54,187,940 - 54,188,098	UniSTS
RH 3.4 Map	9	480.1	UniSTS
Cytogenetic Map	9	q31	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									68		26	5
Low	3	43	35	23	15	23	8	11	6	35	15	6	8
Below cutoff			22	18	4	18

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001066941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_343571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC103419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000020910 ⟹ ENSRNOP00000020910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	56,630,460 - 56,707,810 (-)	Ensembl
Rnor_6.0 Ensembl	9	61,756,428 - 61,810,417 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095669 ⟹ ENSRNOP00000076615

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	56,651,651 - 56,707,810 (-)	Ensembl

RefSeq Acc Id:

XM_343571 ⟹ XP_343572

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	64,146,062 - 64,202,342 (-)	NCBI
mRatBN7.2	9	56,651,617 - 56,707,829 (-)	NCBI
Rnor_6.0	9	61,754,859 - 61,810,992 (-)	NCBI
Rnor_5.0	9	61,438,131 - 61,494,253 (-)	NCBI
RGSC_v3.4	9	53,958,426 - 54,012,631 (-)	RGD

Sequence:

show sequence

TCCCTCTCTTCTTTCCTCTCCCTCTTTCCCTCCCTTCCTTCCCCTGTCCTCCCCCCTCCCTTCT
GCTTCCTTGGTAGAAGCGGGGAAGTGAGCTTCAGCACAGGACAGACCAGAGAAAACAGAAAGAA
CCGCATCACTTTGGCTGACTTTATCTTCTTCTATCCGTAGATAATCACACCAGAGTTGCCTTTA
ATTCCGTTTCTGGACACCTCTTTTCCATTCAGCCAACTGGGTGAGACAAAGCTGGTTGGTGCCC
TGAGCCGCAGAACTCTGGTAGGGGGCTGGCTGGCTGTAAATTGACGTGGCATGGAAATTCTCCA
CTAAGTTGCAGCAGCTTGCGAGCTCCTCAAAGACCGAGCCCAGCCTCCGGGAGCTAGAGCTAAA
CCACGGGCTCAGTGACCTTACAGAAGAATGGATAAAGTCCCCAGCTCTGCGCCTCGGACCCGCC
GTTTCCTTTCTGGCTATCTGTCATTTCGCTGAAAACCAAGTCAAAGTCTGTAACTTTGTTTTCG
CAGCTTAAACAACAAAACTGACTGCTCTTGCCCCCGCAGTCTGAACTCCTTGGAGACTTTGCCA
TGGGGTGCGGGCTTAGGAAGCTGGAAGACCCTGATGAAAGCAGCCCTGGAAAGATATTTTCTAC
CCTGAAGAGACCGCAAGTGGAAACAAAGACAGAATTTGCTTATGAATATGCACTGCTGGATTTT
ACTTTACAAGCTTCCACAAATCCAGAAGTCATCAAGATAAATTCAGTCCTGGATATAGTTGCCA
AAGTGGAAGACTATTATCTTAAGGGCTATGTTGTTGGGGCCATTCACCCTGTTATACAGCCTGT
GGGGCAGCGGAAGCACCTCCCAGCAAGTCATCTGTACAGGGCGGTGCTATCCCGAGTGAAGCTA
AGCTCCAAGCATTCAGCCGCAGGCGGACAAAGGCGCGCCAGGCTTGTGATAGAGGAGTGCCCGC
TAACGTGTGAGACGCAAGGGAACGACTCTGCAAAGGAACTCATAGACAAGGTTAATGCTGCTGC
TAAGAGAGGGATGAGATTTGTCGGATTTGTACCGCAGCACTGCTCGCCATCTAAGCACTGCAAT
GGTGCCAGCCAGGATGGAGTTGCCGAGTCGGAGCTGCACAAGAGACAGGGTTCACAAGACAACT
GCAAAAGCTTGAACGACGGCACCTTGTGGGAGAGTGGAGTGGAGGAGGAACCTCAGCCTGAAAG
TGGACAGCATCAGACTGAGGGAAACAGCAGCCTCAGCTACTCTAACCCAAAGCGGGGAGAAGCC
CCAGATAATAAGGTGTATATGGTCTTCAATGCTTTTGAAGAGGACTCGGCCTGCTGGACCTATC
AGGAGGGCATCCTGTCCATGAAAGTGACAAGGAAGGGAGCTGTCATCAGCACGCTGGACGCCAA
CTGGCTAGAACTAACCACATTTTATTACAAGCAAGGCTTGTCTTTAGTTGACTCTTTTGTGTGC
TGGGAGACACCTAAAGGGGACCAGTTACCTAAATCTTTGGAAGGCTTTTTTATCTATGAAGAAG
AAGGGTCTGGAGTCCCAGGCTCTAACAGGAGAGGAAATGATGCCATTGTAGTAGAACAGTGGAC
AGTCATTGAGGGCTGTGAAATCAAGACTGATTATGGCCCCCTGCTGCATACGCTGGCTGAATTT
GGATGGCTTCTGACAAGCGTGTTGCCCACACCTATATTGAGACACGACAGTGAAGGGAACTTGG
CTACCAAGCAGGTCGTGTTTCTCCAAAGGCCAGTGACATGGAACTCAGCTGCTCAGACCCCAGA
AAGGAAAGGCGGCCGGCTGCTGAGGGGTGAAGACAGAAACAAGGTCGGCAGCAGGAGCATTGGC
CTCGACACAAGCGAGTGCCAACCCGCAGGAGGCCGAGCCCCTCTTGAGGAGGGTCCCCTCTCTC
CCTCCAGAGAGTGTTGGACCAAGGAAGAGCGGCCCACACAGAGCGACAGCTTCTCCGGGTTCAG
TGGCAGCGACAGTGTCCTCCGGGAGCTAGATGATGGACAGTTTGACCAGGAAGAGGGCGTGACA
CAGGTCACTTGCATGTGAGTTGCCAGGTGACCCCACAGAAGGCCTTGTAAATAGTTATTAAAAT
GACTGCCATCTGACTTTATTTCAATACTATCTTCATTTATGTAATGTTTTTTAATTTCCAGGCT
CAGCCTTCCCCTAATCTATGTAAACTTTGTCTCAACCTCTGAGACAAGGAAGAATAACCAACTA
TTTATCAATATAAAAGCTTACACTCCTCTCGACTGTGTAAACAGATGTCTCATCTGGTCATTAA
GCCACAACCTGGTTCACTTCCCCACAAGTGGACAAAAATCAGTATTTCTCATCAGGCCTATTAA
AAAGGCTGACTATCCAAATCATTTCAACCAATTAGAGCCTTCTCAGGAAGCTACAGCCTCAATT
AAACTAAAAAATATTCCTTCTTCCCTGTCTCTGTCCCTGTCTCCCATGGACACAGACTCGTGGA
AATAACTATTCCCTGCCTACAGCAGTTAATCTAATTTTTGTCTCTTACTGTTGTATGTCCAGAC
AAAGTGAGCCCAATTTGTCAAAAGTCTTCAAAAAAACTTCTTTCCTATGTCTTTTCTTTCAAAG
GGGCACCATGTGGCCAGTCCTACAGTGAACCATTAACTTTGTCATTGTTGGTCCCAATAGCCCA
CCAGTGGCATAAAACAGAATTTCTTAAGTCAGTTAAGACTGACAGGATGGCGTTTGCCATGCAA
GCCTTATGACCCAAGTTCAGTCTCTGGAACCCATAGAGATATAGAAACAGATAGAAGTTCTACA
ACAGTTGACCTCCAAGCCAGTACTTGTTCCTCTGTGCCCTAGTACGTGCTCGTGCACGCACAGT
AAAACTAACTTTTTTTTTTTGGTTTTTTTTTTTTTATTCTTTTTTTCGGAGCTGGGGACCGAAC
CCAGGGCCTTGCGCTTCCTAGGCAAGCGCTCTACCAACCCCTAAACTAACTTTTTAAAAAGTCA
CTGACGAGGGGTCACTATGGAGGGCACTGCATGGCTGACCATGACCGTCTGCCCCGCTCCAATC
TAGGGAGAATTCAACTGGCTGAACCTTCACACCCTGACTGAAAACTGGTGTCCAATAGACAGTG
ACTGACTGGTTCGTGTTTAAAAAGGTGATTTGAAGGAGAGCTCACAATCTCTTTGAGGTTTTTT
TTTATTATTATTATTATTATTCTTTTTTCTGGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTG
CTAGGCAAGTGCTCTACCACTGAGCTAAATCTCCAACCCCGAGCTCACAATCTCAATGTGGAAA
AGTCACGGTGGAGGGAAACATTTCATCTGTGCCAAGCCTATTTTCACCTACTGTGGCTTTTACA
CACTGAGACCTACTCCATGGCCACCTTCCTCCCGCTGCCAGGGAGGCTCTCATCTTGCCCAGTC
TTTACCCAGTAAAGATTCATCTTCTACAGAACAGGGGCCTTTCATTTATGTGTGAAAGGCTGAC
CTCCAAAAGAATTACAGTTGGCCATGCCGTTAAGTAATTCACATATTATATATTTTTATTGGCT
TGATGTTGACATTGTGAGTCATTTGAGTAATAAACTCTCTTTTGTTGTTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_343572	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL99044	(Get FASTA)	NCBI Sequence Viewer
	EDL99045	(Get FASTA)	NCBI Sequence Viewer
	EDL99046	(Get FASTA)	NCBI Sequence Viewer
	EDL99047	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020910.6
	ENSRNOP00000076615
	ENSRNOP00000076615.1

RefSeq Acc Id:

XP_343572 ⟸ XM_343571

- UniProtKB:

A0A8I5XV77 (UniProtKB/TrEMBL), A6IP14 (UniProtKB/TrEMBL), A6IP13 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGCGLRKLEDPDESSPGKIFSTLKRPQVETKTEFAYEYALLDFTLQASTNPEVIKINSVLDIVA
KVEDYYLKGYVVGAIHPVIQPVGQRKHLPASHLYRAVLSRVKLSSKHSAAGGQRRARLVIEECP
LTCETQGNDSAKELIDKVNAAAKRGMRFVGFVPQHCSPSKHCNGASQDGVAESELHKRQGSQDN
CKSLNDGTLWESGVEEEPQPESGQHQTEGNSSLSYSNPKRGEAPDNKVYMVFNAFEEDSACWTY
QEGILSMKVTRKGAVISTLDANWLELTTFYYKQGLSLVDSFVCWETPKGDQLPKSLEGFFIYEE
EGSGVPGSNRRGNDAIVVEQWTVIEGCEIKTDYGPLLHTLAEFGWLLTSVLPTPILRHDSEGNL
ATKQVVFLQRPVTWNSAAQTPERKGGRLLRGEDRNKVGSRSIGLDTSECQPAGGRAPLEEGPLS
PSRECWTKEERPTQSDSFSGFSGSDSVLRELDDGQFDQEEGVTQVTCM

hide sequence

RefSeq Acc Id:

ENSRNOP00000020910 ⟸ ENSRNOT00000020910

RefSeq Acc Id:

ENSRNOP00000076615 ⟸ ENSRNOT00000095669

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZII1-F1-model_v2	AlphaFold	D3ZII1	1-496	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307304	AgrOrtholog
BioCyc Gene	G2FUF-27530	BioCyc
Ensembl Genes	ENSRNOG00000015594	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020910.8	UniProtKB/TrEMBL
	ENSRNOT00000095669.1	UniProtKB/TrEMBL
InterPro	Raftlin	UniProtKB/TrEMBL
KEGG Report	rno:363231	UniProtKB/TrEMBL
NCBI Gene	363231	ENTREZGENE
PANTHER	PTHR17601	UniProtKB/TrEMBL
	RAFTLIN-2	UniProtKB/TrEMBL
Pfam	Raftlin	UniProtKB/TrEMBL
PhenoGen	Rftn2	PhenoGen
RatGTEx	ENSRNOG00000015594	RatGTEx
UniProt	A0A8I5XV77	ENTREZGENE, UniProtKB/TrEMBL
	A6IP13	ENTREZGENE, UniProtKB/TrEMBL
	A6IP14	ENTREZGENE, UniProtKB/TrEMBL
	D3ZII1_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Rftn2	raftlin family member 2	RGD1307304_predicted	similar to 3222401M22Rik protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1307304_predicted	similar to 3222401M22Rik protein (predicted)	LOC363231_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC363231_predicted	similar to 3222401M22Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar