Rnf166 (ring finger protein 166) - Rat Genome Database

Name: Rnf166
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rnf166 (ring finger protein 166) Rattus norvegicus

Analyze

Symbol:

Rnf166

Name:

ring finger protein 166

RGD ID:

1302950

Description:

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Orthologous to human RNF166 (ring finger protein 166); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; caffeine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

E3 ubiquitin-protein ligase RNF166; MGC2647; RING-type E3 ubiquitin transferase RNF166

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNF166 (ring finger protein 166)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rnf166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnf166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNF166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNF166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNF166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNF166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnf166 (ring finger protein 166)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC15A1 (solute carrier family 15 member 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RNF166 (ring finger protein 166)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnf166 (ring finger protein 166)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rnf166	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	67,437,974 - 67,447,814 (-)	NCBI		GRCr8
mRatBN7.2	19	50,529,434 - 50,539,274 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	50,529,434 - 50,539,274 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	57,324,608 - 57,334,426 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	58,004,363 - 58,014,203 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	60,223,231 - 60,233,049 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	55,290,563 - 55,300,403 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	55,290,563 - 55,300,403 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	65,999,963 - 66,009,803 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	52,755,818 - 52,765,658 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	52,760,698 - 52,770,539 (-)	NCBI
Celera	19	49,768,913 - 49,778,753 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

16Q24.3 Microdeletion Syndrome (ISO)

autosomal recessive chronic granulomatous disease 4 (ISO)

genetic disease (ISO)

KBG syndrome (ISO)

primary ciliary dyskinesia 33 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

aristolochic acid A (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

caffeine (EXP)

carbon nanotube (ISO)

doxorubicin (ISO)

fenthion (ISO)

folic acid (ISO)

lipopolysaccharide (ISO)

methoxyacetic acid (EXP)

methylmercury chloride (EXP)

Monobutylphthalate (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

ozone (ISO)

pirinixic acid (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thalidomide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (IEA)

innate immune response (IEA)

protein polyubiquitination (IBA)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

cytoplasm (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334

Genomics

Comparative Map Data

Rnf166
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	67,437,974 - 67,447,814 (-)	NCBI		GRCr8
mRatBN7.2	19	50,529,434 - 50,539,274 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	50,529,434 - 50,539,274 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	57,324,608 - 57,334,426 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	58,004,363 - 58,014,203 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	60,223,231 - 60,233,049 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	55,290,563 - 55,300,403 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	55,290,563 - 55,300,403 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	65,999,963 - 66,009,803 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	52,755,818 - 52,765,658 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	52,760,698 - 52,770,539 (-)	NCBI
Celera	19	49,768,913 - 49,778,753 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

RNF166
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	88,696,501 - 88,706,408 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	88,696,499 - 88,706,408 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	88,762,909 - 88,772,816 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	87,290,410 - 87,300,301 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	87,290,410 - 87,300,301	NCBI
Celera	16	73,832,574 - 73,842,523 (-)	NCBI		Celera
Cytogenetic Map	16	q24.2-q24.3	NCBI
HuRef	16	74,457,276 - 74,467,225 (-)	NCBI		HuRef
CHM1_1	16	90,174,222 - 90,184,171 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	94,765,637 - 94,775,565 (-)	NCBI		T2T-CHM13v2.0

Rnf166
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	123,192,884 - 123,202,813 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	123,192,886 - 123,202,803 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	122,466,145 - 122,476,074 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	122,466,147 - 122,476,064 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	124,990,047 - 124,999,964 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	125,352,237 - 125,362,154 (-)	NCBI		MGSCv36	mm8
Celera	8	126,695,258 - 126,705,120 (-)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	71.17	NCBI

Rnf166
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955541	2,605,096 - 2,608,866 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955541	2,604,197 - 2,607,969 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNF166
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	98,469,756 - 98,479,783 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	104,381,805 - 104,391,859 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	69,409,777 - 69,419,761 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	89,069,686 - 89,078,115 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

RNF166
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	64,647,411 - 64,655,994 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	64,647,415 - 64,655,999 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	64,658,716 - 64,667,223 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	64,867,446 - 64,875,950 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	64,867,440 - 64,875,950 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	64,893,635 - 64,902,130 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	64,725,193 - 64,733,688 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	65,131,361 - 65,139,870 (+)	NCBI		UU_Cfam_GSD_1.0

Rnf166
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	25,233,929 - 25,240,988 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936641	990,568 - 993,498 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936641	987,476 - 994,535 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF166
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	976,980 - 982,995 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	976,957 - 982,997 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RNF166
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	74,080,605 - 74,091,114 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	74,081,203 - 74,091,018 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	1,589,041 - 1,606,413 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf166
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	878,208 - 886,647 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	877,581 - 886,157 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rnf166
16 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	156
Count of miRNA genes:	118
Interacting mature miRNAs:	138
Transcripts:	ENSRNOT00000018591
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	29322490	57337602	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	19	33838214	55283146	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	33838214	55283146	Rat
5135224	Leukc1	Leukocyte quantity QTL 1			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	19	44340214	55283277	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	49976481	53225766	Rat

Markers in Region

RH133978

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	50,529,629 - 50,529,824 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	55,290,759 - 55,290,953	NCBI	Rnor6.0
Rnor_5.0	19	66,000,159 - 66,000,353	UniSTS	Rnor5.0
RGSC_v3.4	19	52,756,014 - 52,756,208	UniSTS	RGSC3.4
Celera	19	49,769,109 - 49,769,303	UniSTS
RH 3.4 Map	19	700.41	UniSTS
RH 3.4 Map	19	696.7	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	37	30	14	19	14	8	11	74	32	41	11	8
Low		6	27	27		27				3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001002279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC134009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY606065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000018591 ⟹ ENSRNOP00000018591

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	50,529,434 - 50,539,274 (-)	Ensembl
Rnor_6.0 Ensembl	19	55,290,563 - 55,300,403 (-)	Ensembl

RefSeq Acc Id:

NM_001002279 ⟹ NP_001002279

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	67,437,974 - 67,447,814 (-)	NCBI
mRatBN7.2	19	50,529,434 - 50,539,274 (-)	NCBI
Rnor_6.0	19	55,290,563 - 55,300,403 (-)	NCBI
Rnor_5.0	19	65,999,963 - 66,009,803 (-)	NCBI
RGSC_v3.4	19	52,755,818 - 52,765,658 (-)	RGD
Celera	19	49,768,913 - 49,778,753 (-)	RGD

Sequence:

show sequence

CGGCCTGGATAGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCCTGCCCCGGCATGGCGATGTTCC
GCAGCTTGGTGGCCTCCGCGCAGCAACGGCAGCCACCGGCTGGGCCCGCGGGCGGTGACAGCGG
CCTGGAGGCTCAGTTCAGCTGTCCTATCTGCCTGGAGGTGTACCATCGGCCAGTGGCCATCGGC
AGCTGCGGCCACACGTTCTGCGGGGAGTGCCTCCAGCCATGTCTGCAGGTGCCGTCCCCTCTGT
GCCCGCTCTGCCGTCTGCCCTTCGACCCCAAGAAAGTGGACAAAGCCACCCATGTAGAGAAGCA
GCTCTCATCTTACAAAGCACCCTGTCGGGGTTGCAACAAGAAGGTGACACTGGCAAAGATGAGA
GCCCACATCTCCTCCTGCCTGAAGGTCCAGGAGCAGATGGCTAACTGCCCCAAGTTCGTCCCTG
TGGTGCCCACATCCCAGCCCATCCCCAGCAATATCCCCAACCGGTCTACCTTCGCTTGTCCCTA
CTGTGGAGCCCGCAATCTGGATCAGCAGGAGCTGGTGAAGCACTGCGTGGAAAGTCACCGTAGC
GACCCCAACCGTGTGGTATGCCCCATCTGCTCAGCAATGCCCTGGGGGGACCCCAGCTACAAAA
GCGCCAACTTCCTGCAGCACCTGCTGCACCGGCACAAGTTCTCCTACGACACCTTTGTGGACTA
CAGCATCGACGAAGAAGCTGCCTTCCAGGCCGCCCTGGCTCTGTCCCTCTCTGAGAACTGAGGC
ACAGCCTAGCCACCTGCCTTGTCTGGGGCAGAAGACACACTCCAGCCTCAAGGGATAGGGCCGT
TGCCCTTCTGCCCTGGCACCTGCACAGGAGCGCACCTCACCGGGCCAAGTGGAATTTTCCACAA
GGAGAGCTGGTCTCAGAACCCCCAGGGCTGGGATCCTGGCTAGCTGGCCCCTTGTCATCAAGCA
GGGCCACTGGGTCCTGGCCAGCAGCAGTACTGGGTCCTCGGTGCTTCAAGGGGCAGGTGCTGGC
TGCTGGGTTAGAGCCGTTGTCTGCCTTTCCCAGCCTTGATGTCTGTGTGTGGAAAAGGATAAGG
TGCCCTAAGCTGCCAGCCCACCCGGTCCCTAGCTTCGCTTCCACCGTGAGCATTTGGTACTGGC
TTTTGTGATATTTAGGAACCCTGCGTTTTTCTATCTTATCCTGTGTGATAATCTTTTCACATTT
TCTAGAGCAAAGACAAAGCAGTTACTCTTCTATCGCAATACCTGTGTTTGACTAGGCAGAGCAG
TATTTTTATGGAGCATTTACAAAGTTATATTTTTTAAAAAAAATCAAAAATAAACACTTGTGGG
ATCAGTTTAGAGGGAGGAGTATGGGTGTAGCCAGGACTTCATTAGTGTGACAGGTGGAATCCCC
AAGCCATGTGCTTTCTGAGGAGGTGGCCCAAGTCTGCTGTGTGGTTTTTTGGTTGTTTTGTTTT
TTTGATGATGACCCAGAAGAAATCCTAGCATCCCAGCCAATTGTTGTGGCTGCTCTCAGCAGAC
ATAGGACAGCCCAGGTAGAATGGAGCCGTTCTGTCCCCTGTCACCTGCCAGAGCCAACCACAGA
TGGGGACTTCCCTCACCAGTGGTGGAGCCCTTGAGGACCAGAGAGACCTGCTTGGTGGCAGGTC
AGGCCAGAAAACATTTGTCAGATCTTGTTCTGTTCATGGCATAAGTTGCTGTCTTTTCAAAAGA
GTTTAAATAAAGTGTTTCCCAGCACCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001002279	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00058	(Get FASTA)	NCBI Sequence Viewer
	AAT36621	(Get FASTA)	NCBI Sequence Viewer
	EDL92750	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018591
	ENSRNOP00000018591.2
	ENSRNOP00055028325
	ENSRNOP00060022652
	ENSRNOP00065007779
GenBank Protein	Q6J1I7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001002279 ⟸ NM_001002279

- UniProtKB:

Q6J1I7 (UniProtKB/Swiss-Prot), A6IZS2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAMFRSLVASAQQRQPPAGPAGGDSGLEAQFSCPICLEVYHRPVAIGSCGHTFCGECLQPCLQV
PSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRAHISSCLKVQEQMANCP
KFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGD
PSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN

hide sequence

RefSeq Acc Id:

ENSRNOP00000018591 ⟸ ENSRNOT00000018591

Protein Domains

C2HC RNF-type RING-type UIM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6J1I7-F1-model_v2	AlphaFold	Q6J1I7	1-237	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701207

Promoter ID:

EPDNEW_R11731

Type:

initiation region

Name:

Rnf166_1

Description:

ring finger protein 166

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	55,300,410 - 55,300,470	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1302950	AgrOrtholog
BioCyc Gene	G2FUF-5395	BioCyc
Ensembl Genes	ENSRNOG00000013777	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055020449	UniProtKB/Swiss-Prot
	ENSRNOG00060016424	UniProtKB/Swiss-Prot
	ENSRNOG00065006788	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000018591	ENTREZGENE
	ENSRNOT00000018591.4	UniProtKB/Swiss-Prot
	ENSRNOT00055034914	UniProtKB/Swiss-Prot
	ENSRNOT00060028133	UniProtKB/Swiss-Prot
	ENSRNOT00065010558	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7131133	IMAGE-MGC_LOAD
InterPro	Di19_Zn-bd	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	ZF_C2HC_RNF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:365022	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:112557	IMAGE-MGC_LOAD
NCBI Gene	365022	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE RNF166	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC FINGER, RING/FYVE/PHD-TYPE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	zf-C3HC4_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-Di19	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf_C2HC_14	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Rnf166	PhenoGen
PROSITE	ZF_C2HC_RNF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013777	RatGTEx
	ENSRNOG00055020449	RatGTEx
	ENSRNOG00060016424	RatGTEx
	ENSRNOG00065006788	RatGTEx
SMART	RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6IZS2	ENTREZGENE, UniProtKB/TrEMBL
	Q6J1I7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Rnf166	ring finger protein 166			Symbol and Name status set to approved	1299863	APPROVED
2005-09-30	Rnf166				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar