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Gene: Gid8 (GID complex subunit 8 homolog) Rattus norvegicus

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Symbol:

Gid8

Name:

GID complex subunit 8 homolog

RGD ID:

735024

Description:

Predicted to enable protein homodimerization activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway; positive regulation of cell population proliferation; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human GID8 (GID complex subunit 8 homolog); INTERACTS WITH bisphenol A; cocaine; fipronil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

BWK-1; Bwk1; Bwk1 leukemia-related; Bwk1 leukemia-related gene; GID complex subunit 8; GID complex subunit 8 homolog (S. cerevisiae); glucose-induced degradation protein 8 homolog; LOC296466; TWA1; two hybrid associated protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GID8 (GID complex subunit 8 homolog)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gid8 (GID complex subunit 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gid8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GID8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GID8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gid8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GID8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GID8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gid8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gid8 (GID complex subunit 8 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Gid8 (GID complex subunit 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GID8 (GID complex subunit 8 homolog)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gid8b (GID complex subunit 8 homolog b (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gid8a (GID complex subunit 8 homolog a (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG18467	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG18467	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	GID8	Alliance	DIOPT (InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	GID8	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	tag-304	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tag-304	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG6617	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gid8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gid8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	188,203,571 - 188,214,324 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	188,203,619 - 188,212,270 (+)	Ensembl				GRCr8
mRatBN7.2	3	167,826,006 - 167,836,759 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	167,826,060 - 167,834,814 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	172,206,153 - 172,216,898 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	181,165,247 - 181,175,994 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	177,826,936 - 177,837,687 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	176,217,128 - 176,223,645 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	176,217,128 - 176,223,645 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	179,916,193 - 179,922,710 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	169,807,328 - 169,813,809 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	164,750,200 - 164,756,717 (-)	NCBI		Celera
RGSC_v3.1	3	169,713,363 - 169,719,845 (+)	NCBI
Cytogenetic Map	3	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

neuronal ceroid lipofuscinosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

aflatoxin B1 (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cocaine (EXP)

crocidolite asbestos (ISO)

Dibutyl phosphate (ISO)

fipronil (EXP)

folic acid (ISO)

gentamycin (EXP)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

oxaliplatin (EXP)

sodium arsenite (ISO)

titanium dioxide (ISO)

topotecan (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of canonical Wnt signaling pathway (ISO)

positive regulation of cell population proliferation (ISO)

Cellular Component

cell junction (ISO)

cytoplasm (ISO)

cytosol (ISO)

nucleoplasm (ISO)

nucleus (ISO)

ubiquitin ligase complex (ISO)

Molecular Function

protein binding (ISO)

protein homodimerization activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:17467196	PMID:24143168	PMID:27920276	PMID:28829046	PMID:29911972

Genomics

Comparative Map Data

Gid8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	188,203,571 - 188,214,324 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	188,203,619 - 188,212,270 (+)	Ensembl				GRCr8
mRatBN7.2	3	167,826,006 - 167,836,759 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	167,826,060 - 167,834,814 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	172,206,153 - 172,216,898 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	181,165,247 - 181,175,994 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	177,826,936 - 177,837,687 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	176,217,128 - 176,223,645 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	176,217,128 - 176,223,645 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	179,916,193 - 179,922,710 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	169,807,328 - 169,813,809 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	164,750,200 - 164,756,717 (-)	NCBI		Celera
RGSC_v3.1	3	169,713,363 - 169,719,845 (+)	NCBI
Cytogenetic Map	3	q43	NCBI

GID8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	62,938,147 - 62,948,475 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	62,937,060 - 62,948,589 (+)	Ensembl			hg38	GRCh38
GRCh37	20	61,569,499 - 61,579,827 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	61,039,886 - 61,050,272 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	61,039,885 - 61,050,270	NCBI
Celera	20	58,246,068 - 58,256,455 (+)	NCBI		Celera
Cytogenetic Map	20	q13.33	NCBI
HuRef	20	58,286,457 - 58,296,845 (+)	NCBI		HuRef
CHM1_1	20	61,470,450 - 61,480,837 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	64,738,261 - 64,748,596 (+)	NCBI		T2T-CHM13v2.0

Gid8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	180,351,874 - 180,363,392 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	180,351,910 - 180,360,526 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	180,710,122 - 180,721,599 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	180,710,117 - 180,718,733 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	180,447,251 - 180,453,222 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	180,641,954 - 180,647,925 (+)	NCBI		MGSCv36	mm8
Celera	2	184,798,078 - 184,804,046 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	103.26	NCBI

Gid8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955528	1,146,313 - 1,153,093 (-)	Ensembl
ChiLan1.0	NW_004955528	1,146,313 - 1,153,093 (-)	NCBI	ChiLan1.0	ChiLan1.0

GID8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	68,725,223 - 68,735,785 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	68,718,518 - 68,728,904 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	59,325,193 - 59,335,588 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	60,617,762 - 60,627,792 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	60,617,762 - 60,627,792 (+)	Ensembl			panPan2	panpan1.1

GID8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	46,741,165 - 46,751,516 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	46,741,140 - 46,746,352 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	45,925,212 - 45,935,589 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	47,613,526 - 47,623,868 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	47,613,442 - 47,621,203 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	46,711,287 - 46,721,668 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	46,834,422 - 46,844,771 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	47,590,595 - 47,600,986 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gid8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	194,968,978 - 194,975,627 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	10,422,617 - 10,431,837 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	10,422,620 - 10,429,272 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GID8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	62,174,231 - 62,181,107 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	62,174,222 - 62,181,107 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GID8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	1,277,963 - 1,284,925 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	1,274,813 - 1,284,944 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	49,107,241 - 49,114,237 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gid8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	28,701,018 - 28,707,527 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	28,700,817 - 28,707,527 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gid8
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	157,812,384 - 157,818,923 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	72
Count of miRNA genes:	60
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000013609
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	181611379	189428310	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat

Markers in Region

D3Mco44

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	167,830,297 - 167,830,544 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	176,221,290 - 176,221,536	NCBI	Rnor6.0
Rnor_5.0	3	179,920,355 - 179,920,601	UniSTS	Rnor5.0
RGSC_v3.4	3	169,811,454 - 169,811,700	UniSTS	RGSC3.4
Celera	3	164,752,309 - 164,752,555	UniSTS
Cytogenetic Map	3	q43	UniSTS

D3Hmgc16

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	167,830,309 - 167,830,545 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	176,221,302 - 176,221,537	NCBI	Rnor6.0
Rnor_5.0	3	179,920,367 - 179,920,602	UniSTS	Rnor5.0
RGSC_v3.4	3	169,811,466 - 169,811,701	UniSTS	RGSC3.4
Celera	3	164,752,308 - 164,752,543	UniSTS
Cytogenetic Map	3	q43	UniSTS

RH128987

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	167,832,495 - 167,832,688 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	176,223,488 - 176,223,680	NCBI	Rnor6.0
Rnor_5.0	3	179,922,553 - 179,922,745	UniSTS	Rnor5.0
RGSC_v3.4	3	169,813,652 - 169,813,844	UniSTS	RGSC3.4
Celera	3	164,750,165 - 164,750,357	UniSTS
RH 3.4 Map	3	1529.6	UniSTS
Cytogenetic Map	3	q43	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_198743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY156921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013609 ⟹ ENSRNOP00000013609

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	176,217,128 - 176,223,645 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094799 ⟹ ENSRNOP00000090837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	167,826,060 - 167,834,814 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000124655 ⟹ ENSRNOP00000103808

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	188,203,619 - 188,212,270 (+)	Ensembl

RefSeq Acc Id:

NM_198743 ⟹ NP_942038

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	188,203,571 - 188,214,324 (+)	NCBI
mRatBN7.2	3	167,826,006 - 167,836,759 (+)	NCBI
Rnor_6.0	3	176,217,128 - 176,223,645 (+)	NCBI
Rnor_5.0	3	179,916,193 - 179,922,710 (+)	NCBI
RGSC_v3.4	3	169,807,328 - 169,813,809 (+)	RGD
Celera	3	164,750,200 - 164,756,717 (-)	RGD

Sequence:

show sequence

CGGCCGCGGAGCCGCCACCCAGACCCTGTCGCGCGGGAGGCGGGATCCGCACGAAATAAGTCAT
AATGAGTTACGCAGAAAAGCCCGATGAAATAACCAAAGATGAATGGATGGAAAAGCTCAACAAC
TTACATGTTCAGCGCGCAGACATGAACCGACTCATCATGAACTACTTAGTCACAGAGGGCTTTA
AGGAAGCAGCAGAGAAATTTCGGATGGAGTCAGGGATCGAACCAAGTGTGGACCTAGAAACACT
CGATGAGCGAATCAAGATTCGGGAGATGATTCTGAAGGGTCAGATCCAGGAGGCTATTGCCTTG
ATCAACAGCCTCCACCCAGAGCTCCTAGACACAAACCGGTATCTTTACTTCCACCTGCAGCAAC
AGCACCTGATCGAGCTTATCCGTCAGCGAGAGACAGAAGCAGCTTTGGAGTTTGCCCAGACGCA
ACTGGCAGAGCAGGGTGAGGAAAGCAGAGAATGCCTCACAGAAATGGAGCGCACATTGGCCTTG
CTGGCCTTCGATAGCCCTGAGGAGTCGCCCTTTGGAGACCTCCTCCACATGATGCAGAGGCAAA
AGGTGTGGAGTGAAGTTAACCAGGCTGTTCTGGATTATGAGAATCGAGAGTCCACACCCAAGCT
GGCAAAATTACTGAAACTGCTACTTTGGGCTCAGAATGAGCTAGACCAGAAGAAAGTAAAATAT
CCCAAAATGACAGACCTCAGCAAAGGTGTGATTGAGGAGCCCAAGTAGAGCCTGTCCACGGAGC
CAGCACTGTCAATCAGCACAGGACTCCTCCTCTGTGACTGGCAGGTTGTCACTGCAGTAGAGAA
CCTTTCCCCCTGTACTTTTCTTTGGCCCCATTGTTTAAAAGGGGAAAATGGCCTTTTTAAACAC
TGGCAAACCCGTGATGGAAGACACCACCTCTGCCGTGCCCTGGATCCTGAGGGCTGCACACACT
TCAGTTGACTGTCCTCGCGCTTCCGGATCGCTGGTTCCAGAAGATGTGGTTTGCCACCTGTGCT
GCACTGCTGGGAGTGTCACCTCCGCTGAAGGCCTCCCACAGGACAGCACACAAGAAGTGCTGAA
GTGCTGAATGCTTCGACACCTGCTAGCGTGCAGGCAGGCAGGCAGGCAGGCAGGGTCTTATCTT
CCTAGGTCTCACCAGACTTTCATGGTTTTCCTTACCCCTTCTTTTTTTTCTTTTTCTTCCTCCT
TTTGTTCCTTCATAGGAAAGAATATATAAATTTGTAAATCTTAATTCAAAGATAACTTTGGTGT
GGGTACTGAGTTTGGTTTGGTTCTTTGCCTTTGCCTTTTGGTGTGGGCTGTGTGGCTTTTGGGA
GGAAGGGTGTGTGTGTGAAAGGTGAGGCTGTGGGTTTGTTTTCTCTTTTTTTTTTTTTTAATTT
TCAAAATATATTTTGGGTGCTGTAAAAAAACCTCGTGCCG

hide sequence

Protein Sequences


Protein RefSeqs	NP_942038	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO18337	(Get FASTA)	NCBI Sequence Viewer
	EDL88790	(Get FASTA)	NCBI Sequence Viewer
	EDL88791	(Get FASTA)	NCBI Sequence Viewer
	EDL88792	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000103808
	ENSRNOP00000103808.1

RefSeq Acc Id:

NP_942038 ⟸ NM_198743

- UniProtKB:

Q6YDN8 (UniProtKB/TrEMBL), A0A8I6AEK9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSYAEKPDEITKDEWMEKLNNLHVQRADMNRLIMNYLVTEGFKEAAEKFRMESGIEPSVDLETL
DERIKIREMILKGQIQEAIALINSLHPELLDTNRYLYFHLQQQHLIELIRQRETEAALEFAQTQ
LAEQGEESRECLTEMERTLALLAFDSPEESPFGDLLHMMQRQKVWSEVNQAVLDYENRESTPKL
AKLLKLLLWAQNELDQKKVKYPKMTDLSKGVIEEPK

hide sequence

Ensembl Acc Id:

ENSRNOP00000013609 ⟸ ENSRNOT00000013609

Ensembl Acc Id:

ENSRNOP00000090837 ⟸ ENSRNOT00000094799

Ensembl Acc Id:

ENSRNOP00000103808 ⟸ ENSRNOT00000124655

Protein Domains

CTLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6YDN8-F1-model_v2	AlphaFold	Q6YDN8	1-228	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692740

Promoter ID:

EPDNEW_R3265

Type:

initiation region

Name:

Gid8_1

Description:

GID complex subunit 8 homolog

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	176,217,088 - 176,217,148	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735024	AgrOrtholog
BioCyc Gene	G2FUF-46322	BioCyc
Ensembl Genes	ENSRNOG00000010180	Ensembl
	ENSRNOG00000065606	Ensembl
	ENSRNOG00000082598	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000124655	ENTREZGENE
	ENSRNOT00000124655.1	UniProtKB/TrEMBL
InterPro	CTLH/CRA	UniProtKB/TrEMBL
	CTLH_C	UniProtKB/TrEMBL
	LisH_dimerisation	UniProtKB/TrEMBL
	Ran-bd_prot-like_CRA_domain	UniProtKB/TrEMBL
	Ubq-SigPath_Reg	UniProtKB/TrEMBL
KEGG Report	rno:296466	UniProtKB/TrEMBL
NCBI Gene	296466	ENTREZGENE
PANTHER	RAN BINDING PROTEIN 9-RELATED	UniProtKB/TrEMBL
Pfam	CLTH	UniProtKB/TrEMBL
	LisH	UniProtKB/TrEMBL
PhenoGen	Gid8	PhenoGen
PROSITE	CTLH	UniProtKB/TrEMBL
	LISH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010180	RatGTEx
	ENSRNOG00000065606	RatGTEx
	ENSRNOG00000082598	RatGTEx
SMART	CRA	UniProtKB/TrEMBL
	CTLH	UniProtKB/TrEMBL
	LisH	UniProtKB/TrEMBL
UniProt	A0A8I6AEK9	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LGR9_RAT	UniProtKB/TrEMBL
	Q6YDN8	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-04-18	Gid8	GID complex subunit 8 homolog	Gid8	GID complex subunit 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Gid8	GID complex subunit 8 homolog (S. cerevisiae)	Bwk1	Bwk1 leukemia-related gene	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Gid8	GID complex subunit 8	Gid8	GID complex subunit 8 homolog (S. cerevisiae)	Name changed	629549	APPROVED
2005-11-17	Bwk1	Bwk1 leukemia-related gene	LOC296466	BWK-1	Symbol and Name updated	1299863	APPROVED
2005-09-30	LOC296466				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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