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Gene: Nit1 (nitrilase 1) Rattus norvegicus

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Symbol:

Nit1

Name:

nitrilase 1

RGD ID:

727821

Description:

Predicted to enable deaminated glutathione amidase activity. Predicted to be involved in amide catabolic process. Predicted to be located in mitochondrion. Orthologous to human NIT1 (nitrilase 1); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

deaminated glutathione amidase; dGSH amidase; MGC95151; nitrilase homolog 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NIT1 (nitrilase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NIT1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Nit1 (nitrilase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NIT1 (nitrilase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nit1 (nitrilase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nit1 (nitrilase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	NIT2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	NitFhit	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nft-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nit1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nit1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	86,298,387 - 86,305,770 (-)	Ensembl				GRCr8
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,765,941 - 83,773,332 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	86,275,650 - 86,279,086 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,673,861 - 87,677,297 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,909,943 - 84,913,387 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,722,374 - 89,725,806 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	94,349,703 - 94,353,139 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	87,242,619 - 87,246,055 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	83,400,571 - 83,404,007 (-)	NCBI		Celera
RGSC_v3.1	13	87,431,510 - 87,434,235 (-)	NCBI
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Small Vessel Disease 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amiodarone (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP,ISO)

Bufotalin (ISO)

buspirone (EXP)

cadmium dichloride (EXP,ISO)

CGP 52608 (ISO)

chloroprene (EXP)

clofibrate (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

diazinon (EXP,ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

doxorubicin (ISO)

enzyme inhibitor (ISO)

fenpyroximate (ISO)

folic acid (ISO)

gentamycin (EXP)

iodide salt (EXP)

ivermectin (ISO)

L-ethionine (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nefazodone (EXP)

Nonylphenol (EXP)

okadaic acid (ISO)

omeprazole (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

picoxystrobin (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

progesterone (ISO)

rotenone (ISO)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

tebufenpyrad (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amide catabolic process (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

mitochondrion (IEA,ISO)

Molecular Function

deaminated glutathione amidase activity (IEA,ISO,ISS)

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
3.	The nitrilase superfamily: classification, structure and function.	Pace HC and Brenner C, Genome Biol 2001;2(1):REVIEWS0001. Epub 2001 Jan 15.
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16864578	PMID:18614015	PMID:19053248	PMID:21630459	PMID:21873635	PMID:23376485	PMID:28373563

Genomics

Comparative Map Data

Nit1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	86,298,387 - 86,305,770 (-)	Ensembl				GRCr8
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,765,941 - 83,773,332 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	86,275,650 - 86,279,086 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,673,861 - 87,677,297 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,909,943 - 84,913,387 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,722,374 - 89,725,806 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	94,349,703 - 94,353,139 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	87,242,619 - 87,246,055 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	83,400,571 - 83,404,007 (-)	NCBI		Celera
RGSC_v3.1	13	87,431,510 - 87,434,235 (-)	NCBI
Cytogenetic Map	13	q24	NCBI

NIT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	161,118,105 - 161,125,445 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	161,118,082 - 161,125,445 (+)	Ensembl			hg38	GRCh38
GRCh37	1	161,087,895 - 161,095,235 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	159,354,515 - 159,357,481 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	157,900,963 - 157,903,930	NCBI
Celera	1	134,155,024 - 134,162,397 (+)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	132,445,260 - 132,452,414 (+)	NCBI		HuRef
CHM1_1	1	162,484,103 - 162,491,482 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	160,255,512 - 160,262,920 (+)	NCBI		T2T-CHM13v2.0

Nit1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	171,168,145 - 171,173,209 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	171,165,576 - 171,173,214 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	171,340,571 - 171,345,656 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	171,338,008 - 171,345,646 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	173,272,368 - 173,275,776 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	173,178,919 - 173,182,301 (-)	NCBI		MGSCv36	mm8
Celera	1	173,793,725 - 173,797,135 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	79.35	NCBI

Nit1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	12,882,765 - 12,888,479 (+)	Ensembl
ChiLan1.0	NW_004955468	12,882,765 - 12,885,642 (+)	NCBI	ChiLan1.0	ChiLan1.0

NIT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	88,730,947 - 88,733,951 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	88,421,282 - 88,424,287 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	136,530,490 - 136,533,619 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	140,443,751 - 140,446,874 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	140,443,763 - 140,449,831 (+)	Ensembl			panPan2	panpan1.1

NIT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	21,352,236 - 21,355,636 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	21,348,486 - 21,356,260 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	21,426,271 - 21,429,701 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	21,469,764 - 21,473,194 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	21,466,017 - 21,473,864 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	21,357,920 - 21,361,348 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	21,771,943 - 21,775,377 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	22,181,173 - 22,184,607 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	7,223,645 - 7,228,035 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936903	431,897 - 439,718 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936903	432,585 - 436,697 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NIT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	89,320,712 - 89,327,066 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	89,323,598 - 89,327,057 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	97,180,537 - 97,183,754 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NIT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	2,859,582 - 2,862,688 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	2,860,008 - 2,862,601 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	1,906,929 - 1,910,035 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nit1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	254,766 - 257,759 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624794	254,766 - 258,046 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nit1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	50,507,204 - 50,510,660 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nit1
8 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	37
Count of miRNA genes:	34
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000005194
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	71610804	89333251	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	71610804	89333251	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	71610804	89333251	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	62424592	88113509	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

AF069985

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,769,929 - 83,770,043 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,722,412 - 89,722,525	NCBI	Rnor6.0
Rnor_5.0	13	94,349,745 - 94,349,858	UniSTS	Rnor5.0
RGSC_v3.4	13	87,242,661 - 87,242,774	UniSTS	RGSC3.4
Celera	13	83,400,613 - 83,400,726	UniSTS
Cytogenetic Map	13	q24	UniSTS

BF387362

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,772,326 - 83,772,511 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,724,809 - 89,724,993	NCBI	Rnor6.0
Rnor_5.0	13	94,352,142 - 94,352,326	UniSTS	Rnor5.0
RGSC_v3.4	13	87,245,058 - 87,245,242	UniSTS	RGSC3.4
Celera	13	83,403,010 - 83,403,194	UniSTS
RH 3.4 Map	13	554.6	UniSTS
Cytogenetic Map	13	q24	UniSTS

RH134594

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	86,302,182 - 86,302,398 (+)	Marker Load Pipeline
mRatBN7.2	13	83,769,737 - 83,769,952 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,722,220 - 89,722,434	NCBI	Rnor6.0
Rnor_5.0	13	94,349,553 - 94,349,767	UniSTS	Rnor5.0
RGSC_v3.4	13	87,242,469 - 87,242,683	UniSTS	RGSC3.4
Celera	13	83,400,421 - 83,400,635	UniSTS
RH 3.4 Map	13	554.9	UniSTS
Cytogenetic Map	13	q24	UniSTS

AA818913

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,770,038 - 83,770,134 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,722,521 - 89,722,616	NCBI	Rnor6.0
Rnor_5.0	13	94,349,854 - 94,349,949	UniSTS	Rnor5.0
RGSC_v3.4	13	87,242,770 - 87,242,865	UniSTS	RGSC3.4
Celera	13	83,400,722 - 83,400,817	UniSTS
RH 3.4 Map	13	550.2	UniSTS
Cytogenetic Map	13	q24	UniSTS

AA945617

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,770,017 - 83,770,166 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,722,500 - 89,722,648	NCBI	Rnor6.0
Rnor_5.0	13	94,349,833 - 94,349,981	UniSTS	Rnor5.0
RGSC_v3.4	13	87,242,749 - 87,242,897	UniSTS	RGSC3.4
Celera	13	83,400,701 - 83,400,849	UniSTS
RH 3.4 Map	13	562.2	UniSTS
Cytogenetic Map	13	q24	UniSTS

W57327

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	86,304,518 - 86,305,095 (+)	Marker Load Pipeline
mRatBN7.2	13	83,772,072 - 83,772,649 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,724,555 - 89,725,131	NCBI	Rnor6.0
Rnor_5.0	13	94,351,888 - 94,352,464	UniSTS	Rnor5.0
RGSC_v3.4	13	87,244,804 - 87,245,380	UniSTS	RGSC3.4
Celera	13	83,402,756 - 83,403,332	UniSTS
Cytogenetic Map	13	q24	UniSTS

PMC21147P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,772,584 - 83,772,678 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,725,067 - 89,725,160	NCBI	Rnor6.0
Rnor_5.0	13	94,352,400 - 94,352,493	UniSTS	Rnor5.0
RGSC_v3.4	13	87,245,316 - 87,245,409	UniSTS	RGSC3.4
Celera	13	83,403,268 - 83,403,361	UniSTS
Cytogenetic Map	13	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001082580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001305646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001305647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_182668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY300752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB576182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO558072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV073582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM045849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214471	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005194 ⟹ ENSRNOP00000005194

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	86,302,338 - 86,305,195 (-)	Ensembl
mRatBN7.2 Ensembl	13	83,769,891 - 83,772,749 (-)	Ensembl
Rnor_6.0 Ensembl	13	89,722,374 - 89,725,806 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111317 ⟹ ENSRNOP00000087783

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	86,298,387 - 86,305,770 (-)	Ensembl
mRatBN7.2 Ensembl	13	83,765,941 - 83,773,325 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117822 ⟹ ENSRNOP00000096370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	86,302,338 - 86,305,770 (-)	Ensembl
mRatBN7.2 Ensembl	13	83,769,892 - 83,773,332 (-)	Ensembl

RefSeq Acc Id:

NM_001082580 ⟹ NP_001076049

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI
Rnor_5.0	13	94,349,703 - 94,353,139 (-)	NCBI
RGSC_v3.4	13	87,242,619 - 87,246,055 (-)	RGD
Celera	13	83,400,571 - 83,404,007 (-)	RGD

Sequence:

show sequence

CCCACTTGCTCCTGCGCTTCTGGCTTCTGGCAGCTCTTCAGATCCGACCCTGCGAATGGTTTTG
GCTGTGTCTTCATGTAGGACCTACTCCCCAACCCTGCCTGCTGCGGCTGGGCTTCATCACCAGG
CCTCCTCATCAACTCCTGTCCCTTCTGTGTACCGGATACCGATTACCTCAAATCTCAGTACTTT
GTACTCAGCCCAGGCCCAGAGCCATGGCAGAGTCCTCATCGACTTCCTGGGAGCTGCCCCTGGT
GGCTGTGTGCCAGGTAACATCAACACCAAACAAGCAAGAGAACTTTAAAACGTGTGCTGAGCTG
GTTCAAGAGGCTACCAGACTGGGCGCTTGCCTGGCCTTTCTGCCTGAGGCATTTGACTTTATTG
CACGAAATCCTGCCGAGACATTACTCCTGTCCGAACCACTGGATGGGGACCTTTTGGGACAATA
TAGCCAGCTTGCCAGGGAATGTGGAATCTGGCTGTCCTTGGGTGGTTTCCACGAGCGTGGCCAA
GACTGGGAGCAGACTCAGAAAATCTACAATTGTCATGTGCTTCTGAACAGCAAGGGATCAGTAG
TGGCCAGTTACAGGAAGACACATCTATGTGATGTAGAGATCCCAGGTCAGGGGCCTATGAGAGA
AAGCAACTATACCATGCCTGGATACGCTCTTGAACCACCTGTCAAGACACCAGCAGGCAAGGTT
GGTCTAGCAATCTGTTATGACATGCGGTTCCCTGAACTTTCTCTGAAATTGGCTCAAGCTGGGG
CAGAAATACTTACTTATCCTTCAGCCTTTGGATCTGTTACCGGCCCAGCCCACTGGGAGGTGCT
GCTGCGGGCCCGCGCCATTGAGTCTCAGTGCTACGTGATAGCAGCAGCACAGTGTGGACGCCAC
CATGAGACAAGAGCAAGTTACGGCCACAGCATGGTGGTTGACCCCTGGGGCACAGTGGTGGCCA
GCTGTTCCGAGGGACCAGGCCTTTGCCTTGCTCGAATTGATCTCCACTTTCTGCAACAGATGCG
CCAACACTTGCCTGTGTTCCAGCATCGCAGACCTGACCTTTATGGCAGTCTCCTGCCACTCTCC
TAATGTTTTTAATTTCTGTTGGTTGAGACAGACAAACACACGCCAACTGTGAGGTGATGCTACC
GTGACTTGTAGGCTGGACCCAAGCACGGTTCCCTTCACTTGCAGGACTTAACTCTCCTAATGGA
ACACAGGCTCAATCAAGTCCATGGGAAAGAAGAGACTTTGACCTGATCTCAGATTTCAGTTTCA
GAAAAATGAAATTTTATATAGTCACTGTTTATTTCATGAAAACTGAAGTTGTGCTGAGGGCTGA
GCAGCACTGGCATTGAAAAAAAATATAATAATCAATCATAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001305646 ⟹ NP_001292575

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI
Celera	13	83,400,571 - 83,404,007 (-)	NCBI

Sequence:

show sequence

CCCACTTGCTCCTGCGCTTCTGGCTTCTGGCAGCTCTTCAGATCCGACCCTGCGAATGGTTTTG
GCTGTGTCTTCATGCCTCCTCATCAACTCCTGTCCCTTCTGTGTACCGGATACCGATTACCTCA
AATCTCAGTACTTTGTACTCAGCCCAGGCCCAGAGCCATGGCAGAGTCCTCATCGACTTCCTGG
GAGCTGCCCCTGGTGGCTGTGTGCCAGGTAACATCAACACCAAACAAGCAAGAGAACTTTAAAA
CGTGTGCTGAGCTGGTTCAAGAGGCTACCAGACTGGGCGCTTGCCTGGCCTTTCTGCCTGAGGC
ATTTGACTTTATTGCACGAAATCCTGCCGAGACATTACTCCTGTCCGAACCACTGGATGGGGAC
CTTTTGGGACAATATAGCCAGCTTGCCAGGGAATGTGGAATCTGGCTGTCCTTGGGTGGTTTCC
ACGAGCGTGGCCAAGACTGGGAGCAGACTCAGAAAATCTACAATTGTCATGTGCTTCTGAACAG
CAAGGGATCAGTAGTGGCCAGTTACAGGAAGACACATCTATGTGATGTAGAGATCCCAGGTCAG
GGGCCTATGAGAGAAAGCAACTATACCATGCCTGGATACGCTCTTGAACCACCTGTCAAGACAC
CAGCAGGCAAGGTTGGTCTAGCAATCTGTTATGACATGCGGTTCCCTGAACTTTCTCTGAAATT
GGCTCAAGCTGGGGCAGAAATACTTACTTATCCTTCAGCCTTTGGATCTGTTACCGGCCCAGCC
CACTGGGAGGTGCTGCTGCGGGCCCGCGCCATTGAGTCTCAGTGCTACGTGATAGCAGCAGCAC
AGTGTGGACGCCACCATGAGACAAGAGCAAGTTACGGCCACAGCATGGTGGTTGACCCCTGGGG
CACAGTGGTGGCCAGCTGTTCCGAGGGACCAGGCCTTTGCCTTGCTCGAATTGATCTCCACTTT
CTGCAACAGATGCGCCAACACTTGCCTGTGTTCCAGCATCGCAGACCTGACCTTTATGGCAGTC
TCCTGCCACTCTCCTAATGTTTTTAATTTCTGTTGGTTGAGACAGACAAACACACGCCAACTGT
GAGGTGATGCTACCGTGACTTGTAGGCTGGACCCAAGCACGGTTCCCTTCACTTGCAGGACTTA
ACTCTCCTAATGGAACACAGGCTCAATCAAGTCCATGGGAAAGAAGAGACTTTGACCTGATCTC
AGATTTCAGTTTCAGAAAAATGAAATTTTATATAGTCACTGTTTATTTCATGAAAACTGAAGTT
GTGCTGAGGGCTGAGCAGCACTGGCATTGAAAAAAAATATAATAATCAATCATAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001305647 ⟹ NP_001292576

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,302,334 - 86,304,791 (-)	NCBI
mRatBN7.2	13	83,769,888 - 83,772,345 (-)	NCBI
Rnor_6.0	13	89,722,370 - 89,724,827 (-)	NCBI
Celera	13	83,400,571 - 83,403,028 (-)	NCBI

Sequence:

show sequence

AAAGGTCTGCCTGGGCTACAAAAAGACCCGGTCTCAAAGGGGAGGTAAAATCAGAAAAAAAAAA
AGCCCAGAGCCATGGCAGAGTCCTCATCGACTTCCTGGGAGCTGCCCCTGGTGGCTGTGTGCCA
GGTAACATCAACACCAAACAAGCAAGAGAACTTTAAAACGTGTGCTGAGCTGGTTCAAGAGGCT
ACCAGACTGGGCGCTTGCCTGGCCTTTCTGCCTGAGGCATTTGACTTTATTGCACGAAATCCTG
CCGAGACATTACTCCTGTCCGAACCACTGGATGGGGACCTTTTGGGACAATATAGCCAGCTTGC
CAGGGAATGTGGAATCTGGCTGTCCTTGGGTGGTTTCCACGAGCGTGGCCAAGACTGGGAGCAG
ACTCAGAAAATCTACAATTGTCATGTGCTTCTGAACAGCAAGGGATCAGTAGTGGCCAGTTACA
GGAAGACACATCTATGTGATGTAGAGATCCCAGGTCAGGGGCCTATGAGAGAAAGCAACTATAC
CATGCCTGGATACGCTCTTGAACCACCTGTCAAGACACCAGCAGGCAAGGTTGGTCTAGCAATC
TGTTATGACATGCGGTTCCCTGAACTTTCTCTGAAATTGGCTCAAGCTGGGGCAGAAATACTTA
CTTATCCTTCAGCCTTTGGATCTGTTACCGGCCCAGCCCACTGGGAGGTGCTGCTGCGGGCCCG
CGCCATTGAGTCTCAGTGCTACGTGATAGCAGCAGCACAGTGTGGACGCCACCATGAGACAAGA
GCAAGTTACGGCCACAGCATGGTGGTTGACCCCTGGGGCACAGTGGTGGCCAGCTGTTCCGAGG
GACCAGGCCTTTGCCTTGCTCGAATTGATCTCCACTTTCTGCAACAGATGCGCCAACACTTGCC
TGTGTTCCAGCATCGCAGACCTGACCTTTATGGCAGTCTCCTGCCACTCTCCTAATGTTTTTAA
TTTCTGTTGGTTGAGACAGACAAACACACGCCAACTGTGAGGTGATGCTACCGTGACTTGTAGG
CTGGACCCAAGCACGGTTCCCTTCACTTGCAGGACTTAACTCTCCTAATGGAACACAGGCTCAA
TCAAGTCCATGGGAAAGAAGAGACTTTGACCTGATCTCAGATTTCAGTTTCAGAAAAATGAAAT
TTTATATAGTCACTGTTTATTTCATGAAAACTGAAGTTGTGCTGAGGGCTGAGCAGCACTGGCA
TTGAAAAAAAATATAATAATCAATCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

hide sequence

RefSeq Acc Id:

NM_182668 ⟹ NP_872609

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,302,334 - 86,305,770 (-)	NCBI
mRatBN7.2	13	83,769,888 - 83,773,324 (-)	NCBI
Rnor_6.0	13	89,722,370 - 89,725,806 (-)	NCBI
Rnor_5.0	13	94,349,703 - 94,353,139 (-)	NCBI
RGSC_v3.4	13	87,242,619 - 87,246,055 (-)	RGD
Celera	13	83,400,571 - 83,404,007 (-)	RGD

Sequence:

show sequence

CCCACTTGCTCCTGCGCTTCTGGCTTCTGGCAGCTCTTCAGATCCGACCCTGCGAATGGTTTTG
GCTGTGTCTTCATGCTGGGCTTCATCACCAGGCCTCCTCATCAACTCCTGTCCCTTCTGTGTAC
CGGATACCGATTACCTCAAATCTCAGTACTTTGTACTCAGCCCAGGCCCAGAGCCATGGCAGAG
TCCTCATCGACTTCCTGGGAGCTGCCCCTGGTGGCTGTGTGCCAGGTAACATCAACACCAAACA
AGCAAGAGAACTTTAAAACGTGTGCTGAGCTGGTTCAAGAGGCTACCAGACTGGGCGCTTGCCT
GGCCTTTCTGCCTGAGGCATTTGACTTTATTGCACGAAATCCTGCCGAGACATTACTCCTGTCC
GAACCACTGGATGGGGACCTTTTGGGACAATATAGCCAGCTTGCCAGGGAATGTGGAATCTGGC
TGTCCTTGGGTGGTTTCCACGAGCGTGGCCAAGACTGGGAGCAGACTCAGAAAATCTACAATTG
TCATGTGCTTCTGAACAGCAAGGGATCAGTAGTGGCCAGTTACAGGAAGACACATCTATGTGAT
GTAGAGATCCCAGGTCAGGGGCCTATGAGAGAAAGCAACTATACCATGCCTGGATACGCTCTTG
AACCACCTGTCAAGACACCAGCAGGCAAGGTTGGTCTAGCAATCTGTTATGACATGCGGTTCCC
TGAACTTTCTCTGAAATTGGCTCAAGCTGGGGCAGAAATACTTACTTATCCTTCAGCCTTTGGA
TCTGTTACCGGCCCAGCCCACTGGGAGGTGCTGCTGCGGGCCCGCGCCATTGAGTCTCAGTGCT
ACGTGATAGCAGCAGCACAGTGTGGACGCCACCATGAGACAAGAGCAAGTTACGGCCACAGCAT
GGTGGTTGACCCCTGGGGCACAGTGGTGGCCAGCTGTTCCGAGGGACCAGGCCTTTGCCTTGCT
CGAATTGATCTCCACTTTCTGCAACAGATGCGCCAACACTTGCCTGTGTTCCAGCATCGCAGAC
CTGACCTTTATGGCAGTCTCCTGCCACTCTCCTAATGTTTTTAATTTCTGTTGGTTGAGACAGA
CAAACACACGCCAACTGTGAGGTGATGCTACCGTGACTTGTAGGCTGGACCCAAGCACGGTTCC
CTTCACTTGCAGGACTTAACTCTCCTAATGGAACACAGGCTCAATCAAGTCCATGGGAAAGAAG
AGACTTTGACCTGATCTCAGATTTCAGTTTCAGAAAAATGAAATTTTATATAGTCACTGTTTAT
TTCATGAAAACTGAAGTTGTGCTGAGGGCTGAGCAGCACTGGCATTGAAAAAAAATATAATAAT
CAATCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039090511 ⟹ XP_038946439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,302,334 - 86,304,510 (-)	NCBI
mRatBN7.2	13	83,769,888 - 83,772,191 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001076049	(Get FASTA)	NCBI Sequence Viewer
	NP_001292575	(Get FASTA)	NCBI Sequence Viewer
	NP_001292576	(Get FASTA)	NCBI Sequence Viewer
	NP_872609	(Get FASTA)	NCBI Sequence Viewer
	XP_038946439	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87146	(Get FASTA)	NCBI Sequence Viewer
	AAP76395	(Get FASTA)	NCBI Sequence Viewer
	EDL94639	(Get FASTA)	NCBI Sequence Viewer
	EDL94640	(Get FASTA)	NCBI Sequence Viewer
	EDL94641	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005194
	ENSRNOP00000096370
	ENSRNOP00000096370.1
GenBank Protein	Q7TQ94	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_872609 ⟸ NM_182668
- Peptide Label:	isoform a
- UniProtKB:	Q5PQK6 (UniProtKB/Swiss-Prot), Q7TQ94 (UniProtKB/Swiss-Prot), A0A8L2Q1A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLGFITRPPHQLLSLLCTGYRLPQISVLCTQPRPRAMAESSSTSWELPLVAVCQVTSTPNKQEN FKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLLLSEPLDGDLLGQYSQLARECGIWLSLG GFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTMPGYALEPPV KTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIA AAQCGRHHETRASYGHSMVVDPWGTVVASCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLY GSLLPLS hide sequence

RefSeq Acc Id:	NP_001076049 ⟸ NM_001082580
- Peptide Label:	isoform b
- UniProtKB:	A6JFY4 (UniProtKB/TrEMBL), A0A8L2Q1A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAESSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETL LLSEPLDGDLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTH LCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPS AFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASCSEGPGL CLARIDLHFLQQMRQHLPVFQHRRPDLYGSLLPLS hide sequence

RefSeq Acc Id:	NP_001292575 ⟸ NM_001305646
- Peptide Label:	isoform c
- UniProtKB:	A0A8L2Q1A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPPHQLLSLLCTGYRLPQISVLCTQPRPRAMAESSSTSWELPLVAVCQVTSTPNKQENFKTCAE LVQEATRLGACLAFLPEAFDFIARNPAETLLLSEPLDGDLLGQYSQLARECGIWLSLGGFHERG QDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGK VGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGR HHETRASYGHSMVVDPWGTVVASCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGSLLPL S hide sequence

RefSeq Acc Id:	NP_001292576 ⟸ NM_001305647
- Peptide Label:	isoform b
- UniProtKB:	A6JFY4 (UniProtKB/TrEMBL), A0A8L2Q1A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAESSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETL LLSEPLDGDLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTH LCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPS AFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASCSEGPGL CLARIDLHFLQQMRQHLPVFQHRRPDLYGSLLPLS hide sequence

Ensembl Acc Id:

ENSRNOP00000005194 ⟸ ENSRNOT00000005194

RefSeq Acc Id:	XP_038946439 ⟸ XM_039090511
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000096370 ⟸ ENSRNOT00000117822

Ensembl Acc Id:

ENSRNOP00000087783 ⟸ ENSRNOT00000111317

Protein Domains

CN hydrolase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TQ94-F1-model_v2	AlphaFold	Q7TQ94	1-327	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699005

Promoter ID:

EPDNEW_R9529

Type:

initiation region

Name:

Nit1_1

Description:

nitrilase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	89,725,803 - 89,725,863	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727821	AgrOrtholog
BioCyc Gene	G2FUF-17373	BioCyc
Ensembl Genes	ENSRNOG00000003881	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000005194	ENTREZGENE
	ENSRNOT00000117822	ENTREZGENE
	ENSRNOT00000117822.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.60.110.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7129801	IMAGE-MGC_LOAD
InterPro	C-N_Hydrolase	UniProtKB/Swiss-Prot
	C-N_Hydrolase_sf	UniProtKB/Swiss-Prot
	Nit1/2_C-N_Hydrolase	UniProtKB/Swiss-Prot
	UPF0012_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:289222	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95151	IMAGE-MGC_LOAD
NCBI Gene	289222	ENTREZGENE
PANTHER	DEAMINATED GLUTATHIONE AMIDASE	UniProtKB/Swiss-Prot
	NITRILASE-RELATED	UniProtKB/Swiss-Prot
Pfam	CN_hydrolase	UniProtKB/Swiss-Prot
PhenoGen	Nit1	PhenoGen
PROSITE	CN_HYDROLASE	UniProtKB/Swiss-Prot
	UPF0012	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003881	RatGTEx
Superfamily-SCOP	SSF56317	UniProtKB/Swiss-Prot
UniProt	A0A8I6AHC1_RAT	UniProtKB/TrEMBL
	A0A8L2Q1A7	ENTREZGENE, UniProtKB/TrEMBL
	A6JFY4	ENTREZGENE, UniProtKB/TrEMBL
	NIT1_RAT	UniProtKB/Swiss-Prot
	Q5PQK6	ENTREZGENE
	Q7TQ94	ENTREZGENE
UniProt Secondary	Q5PQK6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Nit1	nitrilase 1			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM