Dclre1c (DNA cross-link repair 1C) - Rat Genome Database

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Gene: Dclre1c (DNA cross-link repair 1C) Rattus norvegicus
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Symbol: Dclre1c
Name: DNA cross-link repair 1C
RGD ID: 708574
Description: Predicted to enable 5'-3' DNA exonuclease activity; damaged DNA binding activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in double-strand break repair via nonhomologous end joining; interstrand cross-link repair; and telomere maintenance. Predicted to act upstream of or within several processes, including B cell differentiation; DNA metabolic process; and response to ionizing radiation. Predicted to be part of nonhomologous end joining complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Omenn syndrome; common variable immunodeficiency; severe combined immunodeficiency; and severe combined immunodeficiency with sensitivity to ionizing radiation. Orthologous to human DCLRE1C (DNA cross-link repair 1C); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; primary immunodeficiency pathway; INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA cross-link repair 1C protein; DNA cross-link repair 1C, PSO2 homolog; DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae); protein artemis; SNM1-like; Snm1l
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,684,988 - 79,718,399 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,678,698 - 79,718,734 (-)EnsemblGRCr8
mRatBN7.21774,775,828 - 74,810,089 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,776,935 - 74,809,186 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,230,144 - 78,276,463 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,078,430 - 82,110,655 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,113,583 - 76,159,803 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,782,512 - 78,812,140 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,783,437 - 78,812,111 (-)Ensemblrn6Rnor6.0
Rnor_5.01780,427,567 - 80,455,846 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41785,896,581 - 85,928,644 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,162,589 - 74,190,482 (-)NCBICelera
RGSC_v3.11785,907,414 - 85,939,509 (-)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Lieber MR Annu Rev Biochem. 2010;79:181-211. doi: 10.1146/annurev.biochem.052308.093131.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Moshous D, etal., Cell. 2001 Apr 20;105(2):177-86.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Defective DNA repair and increased genomic instability in Artemis-deficient murine cells. Rooney S, etal., J Exp Med 2003 Mar 3;197(5):553-65.
12. DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency. Volk T, etal., Hum Mol Genet. 2015 Dec 20;24(25):7361-72. doi: 10.1093/hmg/ddv437. Epub 2015 Oct 16.
Additional References at PubMed
PMID:11955432   PMID:12477932   PMID:12504013   PMID:15489334   PMID:23836881   PMID:25941166  


Genomics

Comparative Map Data
Dclre1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,684,988 - 79,718,399 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,678,698 - 79,718,734 (-)EnsemblGRCr8
mRatBN7.21774,775,828 - 74,810,089 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,776,935 - 74,809,186 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,230,144 - 78,276,463 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,078,430 - 82,110,655 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,113,583 - 76,159,803 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,782,512 - 78,812,140 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,783,437 - 78,812,111 (-)Ensemblrn6Rnor6.0
Rnor_5.01780,427,567 - 80,455,846 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41785,896,581 - 85,928,644 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,162,589 - 74,190,482 (-)NCBICelera
RGSC_v3.11785,907,414 - 85,939,509 (-)NCBI
Cytogenetic Map17q12.3NCBI
DCLRE1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381014,897,359 - 14,954,432 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1014,897,359 - 14,954,432 (-)Ensemblhg38GRCh38
GRCh371014,939,358 - 14,996,431 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361014,988,876 - 15,036,100 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341014,989,883 - 15,036,100NCBI
Celera1014,876,909 - 14,924,986 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1014,859,351 - 14,906,283 (-)NCBIHuRef
CHM1_11014,948,990 - 14,996,230 (-)NCBICHM1_1
T2T-CHM13v2.01014,911,323 - 14,968,389 (-)NCBIT2T-CHM13v2.0
Dclre1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,425,112 - 3,475,248 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,425,168 - 3,465,167 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3823,424,061 - 3,474,211 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,424,131 - 3,464,130 (+)Ensemblmm10GRCm38
MGSCv3723,341,403 - 3,378,385 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3623,341,422 - 3,377,160 (+)NCBIMGSCv36mm8
Celera23,375,049 - 3,412,101 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.93NCBI
Dclre1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,461,528 - 19,505,321 (+)Ensembl
ChiLan1.0NW_00495542919,461,446 - 19,501,908 (+)NCBIChiLan1.0ChiLan1.0
DCLRE1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,424,395 - 27,479,455 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,428,821 - 27,485,110 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01014,901,335 - 14,956,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,229,515 - 15,625,331 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,236,558 - 15,269,043 (-)EnsemblpanPan2panpan1.1
DCLRE1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,688,822 - 21,725,021 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl221,688,766 - 21,724,248 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha218,802,137 - 18,838,319 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0221,990,248 - 22,026,469 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl221,990,189 - 22,056,964 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,190,563 - 19,227,141 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,025,548 - 20,061,768 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,652,201 - 20,688,382 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dclre1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093446,920,004 - 6,950,544 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366131,470,365 - 1,501,138 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366131,467,797 - 1,501,107 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCLRE1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,820,053 - 46,868,028 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11046,820,016 - 46,863,848 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,553,277 - 51,596,761 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCLRE1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1914,929,221 - 14,974,791 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl914,929,317 - 14,965,443 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605120,464,546 - 20,515,010 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dclre1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624805555,545 - 592,250 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624805555,444 - 593,548 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dclre1c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1149,878,076 - 9,909,280 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dclre1c
138 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:43
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000021506
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat

Markers in Region
AI072301  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,777,031 - 74,777,247 (+)MAPPERmRatBN7.2
Rnor_6.01778,783,716 - 78,783,931NCBIRnor6.0
Rnor_5.01780,427,665 - 80,427,880UniSTSRnor5.0
RGSC_v3.41785,896,679 - 85,896,894UniSTSRGSC3.4
Celera1774,162,687 - 74,162,902UniSTS
RH 3.4 Map17759.9UniSTS
Cytogenetic Map17q12.3UniSTS
BE111954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21774,802,040 - 74,802,255 (+)MAPPERmRatBN7.2
Rnor_6.01778,804,945 - 78,805,159NCBIRnor6.0
Rnor_5.01780,448,732 - 80,448,946UniSTSRnor5.0
RGSC_v3.41785,921,529 - 85,921,743UniSTSRGSC3.4
Celera1774,183,370 - 74,183,584UniSTS
RH 3.4 Map17764.8UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021506   ⟹   ENSRNOP00000021506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,686,095 - 79,718,464 (-)Ensembl
mRatBN7.2 Ensembl1774,776,935 - 74,809,186 (-)Ensembl
Rnor_6.0 Ensembl1778,783,437 - 78,812,111 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139199   ⟹   ENSRNOP00000106716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,678,698 - 79,718,534 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000163213   ⟹   ENSRNOP00000102035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,686,095 - 79,718,734 (-)Ensembl
RefSeq Acc Id: NM_147145   ⟹   NP_671486
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,686,094 - 79,718,302 (-)NCBI
mRatBN7.21774,776,934 - 74,809,155 (-)NCBI
Rnor_6.01778,783,618 - 78,812,059 (-)NCBI
Rnor_5.01780,427,567 - 80,455,846 (-)NCBI
RGSC_v3.41785,896,581 - 85,928,644 (-)RGD
Celera1774,162,589 - 74,190,482 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095415   ⟹   XP_038951343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,684,988 - 79,709,386 (-)NCBI
mRatBN7.21774,775,828 - 74,800,226 (-)NCBI
RefSeq Acc Id: XM_063276115   ⟹   XP_063132185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,684,988 - 79,710,714 (-)NCBI
RefSeq Acc Id: XR_010058810
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,689,365 - 79,718,399 (-)NCBI
RefSeq Acc Id: NP_671486   ⟸   NM_147145
- UniProtKB: Q8K4H7 (UniProtKB/Swiss-Prot),   Q5XIX3 (UniProtKB/Swiss-Prot),   A0A8L2QAU1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021506   ⟸   ENSRNOT00000021506
RefSeq Acc Id: XP_038951343   ⟸   XM_039095415
- Peptide Label: isoform X1
- UniProtKB: A6JM16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132185   ⟸   XM_063276115
- Peptide Label: isoform X1
- UniProtKB: A6JM16 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106716   ⟸   ENSRNOT00000139199
Ensembl Acc Id: ENSRNOP00000102035   ⟸   ENSRNOT00000163213
Protein Domains
DNA repair metallo-beta-lactamase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIX3-F1-model_v2 AlphaFold Q5XIX3 1-698 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700583
Promoter ID:EPDNEW_R11107
Type:initiation region
Name:Dclre1c_1
Description:DNA cross-link repair 1C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01778,812,089 - 78,812,149EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708574 AgrOrtholog
BioCyc Gene G2FUF-8648 BioCyc
Ensembl Genes ENSRNOG00000015980 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000163213 ENTREZGENE
Gene3D-CATH 3.40.50.12650 UniProtKB/Swiss-Prot
  3.60.15.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134940 IMAGE-MGC_LOAD
InterPro DRMBL UniProtKB/Swiss-Prot
  RibonucZ/Hydroxyglut_hydro UniProtKB/Swiss-Prot
KEGG Report rno:259171 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93142 IMAGE-MGC_LOAD
NCBI Gene 259171 ENTREZGENE
PANTHER DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED UniProtKB/Swiss-Prot
  PROTEIN ARTEMIS UniProtKB/Swiss-Prot
Pfam DRMBL UniProtKB/Swiss-Prot
PhenoGen Dclre1c PhenoGen
RatGTEx ENSRNOG00000015980 RatGTEx
Superfamily-SCOP SSF56281 UniProtKB/Swiss-Prot
UniProt A0A8L2QAU1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L8Q1_RAT UniProtKB/TrEMBL
  A0ABK0LF71_RAT UniProtKB/TrEMBL
  A6JM15_RAT UniProtKB/TrEMBL
  A6JM16 ENTREZGENE, UniProtKB/TrEMBL
  DCR1C_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8K4H7 ENTREZGENE
UniProt Secondary Q8K4H7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Dclre1c  DNA cross-link repair 1C  Dclre1c  DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Dclre1c  DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)  Snm1l  SNM1-like  Symbol and Name updated 1299863 APPROVED