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Gene: Vcpip1 (valosin containing protein interacting protein 1) Rattus norvegicus

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Symbol:

Vcpip1

Name:

valosin containing protein interacting protein 1

RGD ID:

708520

Description:

Enables cysteine-type deubiquitinase activity. Involved in Golgi reassembly; endoplasmic reticulum membrane fusion; and protein ubiquitination. Predicted to be located in nucleus. Predicted to be active in synapse. Orthologous to human VCPIP1 (valosin containing protein interacting protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

deubiquitinating protein VCIP135; deubiquitinating protein VCPIP1; valosin containing protein (p97)/p47 complex interacting protein 1; valosin-containing protein (p97)/p47 complex-interacting protein 135; valosin-containing protein (p97)/p47 complex-interacting protein p135; valosin-containing protein p97/p47 complex-interacting protein 1; valosin-containing protein p97/p47 complex-interacting protein p135; Vcip135; VCP(p97)/p47-interacting protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	14,317,083 - 14,343,724 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	14,316,918 - 14,347,778 (+)	Ensembl				GRCr8
mRatBN7.2	5	9,534,247 - 9,560,889 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	9,534,129 - 9,562,040 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	11,687,600 - 11,714,534 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	13,319,317 - 13,345,988 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	13,022,278 - 13,049,213 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	9,231,180 - 9,257,821 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	9,230,984 - 9,257,934 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	14,031,258 - 14,057,899 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	9,088,295 - 9,114,936 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	9,042,984 - 9,069,572 (+)	NCBI		Celera
RGSC_v3.1	5	9,088,236 - 9,116,073 (+)	NCBI
Cytogenetic Map	5	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

progeria (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clorgyline (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

daidzein (ISO)

daidzein 7-O-beta-D-glucoside (ISO)

diarsenic trioxide (ISO)

ethanol (ISO)

fenofibrate (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

genistein (ISO)

genistein 7-O-beta-D-glucoside (ISO)

glycitein (ISO)

glycitin (ISO)

ketamine (EXP)

miconazole (ISO)

N-nitrosodiethylamine (EXP)

phenethyl caffeate (EXP)

phenobarbital (ISO)

quercetin (ISO)

raloxifene (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

thapsigargin (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

venlafaxine hydrochloride (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA,ISO,ISS)

DNA repair (IEA)

endoplasmic reticulum membrane fusion (IBA,IDA)

Golgi organization (IMP)

Golgi reassembly (IBA,IDA)

protein deubiquitination (IEA,ISO,ISS)

protein K11-linked deubiquitination (IEA,ISO,ISS)

protein K48-linked deubiquitination (IEA,ISO,ISS)

protein ubiquitination (IDA,IEA)

protein-DNA covalent cross-linking repair (IBA,IEA,ISO,ISS)

proteolysis (IEA)

regulation of protein localization to chromatin (IEA,ISO,ISS)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA,ISO)

endoplasmic reticulum (IEA)

Golgi stack (IEA)

nucleus (IEA,ISO,ISS)

synapse (ISO)

Molecular Function

cysteine-type deubiquitinase activity (IBA,IDA,IEA,ISO)

cysteine-type peptidase activity (IEA)

hydrolase activity (IEA)

peptidase activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo.	Uchiyama K, etal., J Cell Biol 2002 Dec 9;159(5):855-66. Epub 2002 Dec 9.
5.	The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle.	Uchiyama K, etal., J Cell Biol 2003 Jun 23;161(6):1067-79. Epub 2003 Jun 16.
6.	VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments.	Wang Y, etal., J Cell Biol 2004 Mar 29;164(7):973-8. Epub 2004 Mar 22.

Additional References at PubMed

PMID:15328197	PMID:16452087	PMID:17550236	PMID:20871144	PMID:21811234	PMID:23827681

Genomics

Comparative Map Data

Vcpip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	14,317,083 - 14,343,724 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	14,316,918 - 14,347,778 (+)	Ensembl				GRCr8
mRatBN7.2	5	9,534,247 - 9,560,889 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	9,534,129 - 9,562,040 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	11,687,600 - 11,714,534 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	13,319,317 - 13,345,988 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	13,022,278 - 13,049,213 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	9,231,180 - 9,257,821 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	9,230,984 - 9,257,934 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	14,031,258 - 14,057,899 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	9,088,295 - 9,114,936 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	9,042,984 - 9,069,572 (+)	NCBI		Celera
RGSC_v3.1	5	9,088,236 - 9,116,073 (+)	NCBI
Cytogenetic Map	5	q11	NCBI

VCPIP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	66,628,487 - 66,667,231 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	66,628,487 - 66,667,231 (-)	Ensembl			hg38	GRCh38
GRCh37	8	67,540,722 - 67,579,466 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	67,705,042 - 67,742,006 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	8	63,535,483 - 63,572,240 (-)	NCBI		Celera
Cytogenetic Map	8	q13.1	NCBI
HuRef	8	63,032,538 - 63,071,315 (-)	NCBI		HuRef
CHM1_1	8	67,597,370 - 67,634,328 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	67,054,243 - 67,092,986 (-)	NCBI		T2T-CHM13v2.0

Vcpip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	9,788,847 - 9,818,607 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	9,788,847 - 9,818,607 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	9,718,622 - 9,748,382 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	9,718,622 - 9,748,382 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	9,713,273 - 9,738,463 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	9,708,406 - 9,733,596 (-)	NCBI		MGSCv36	mm8
Celera	1	9,697,685 - 9,724,194 (-)	NCBI		Celera
Cytogenetic Map	1	A2	NCBI
cM Map	1	2.08	NCBI

Vcpip1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	12,542,479 - 12,567,971 (+)	Ensembl
ChiLan1.0	NW_004955444	12,542,479 - 12,567,971 (+)	NCBI	ChiLan1.0	ChiLan1.0

VCPIP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	82,367,580 - 82,404,559 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	58,007,273 - 58,043,996 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	63,173,116 - 63,210,119 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	64,836,468 - 64,874,818 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	64,842,479 - 64,874,818 (-)	Ensembl			panPan2	panpan1.1

VCPIP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	16,204,932 - 16,235,893 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	16,209,353 - 16,235,586 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	16,520,420 - 16,552,129 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	16,284,665 - 16,316,409 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	16,285,422 - 16,316,353 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	16,316,618 - 16,348,345 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	16,416,266 - 16,447,999 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	16,672,097 - 16,703,810 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Vcpip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	67,409,454 - 67,433,444 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	7,352,018 - 7,376,964 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	7,352,043 - 7,376,023 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VCPIP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	68,073,447 - 68,110,621 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	68,073,403 - 68,109,221 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	74,259,695 - 74,274,272 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VCPIP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	62,506,541 - 62,546,238 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	62,510,808 - 62,546,229 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	78,961,467 - 79,002,860 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vcpip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	24,664,636 - 24,700,416 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624744	24,664,833 - 24,700,416 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Vcpip1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	144,457,029 - 144,487,849 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Vcpip1
162 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	755
Count of miRNA genes:	301
Interacting mature miRNAs:	383
Transcripts:	ENSRNOT00000009136
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	13731153	43590997	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	6922282	37468560	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	8627230	52665523	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
631827	Alc4	Alcohol consumption QTL 4	3.5		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	5	12970480	25683802	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	8627230	53627230	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat

Markers in Region

D1Mit296

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	9,532,612 - 9,532,770 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	9,229,546 - 9,229,703	NCBI	Rnor6.0
Rnor_5.0	5	14,029,624 - 14,029,781	UniSTS	Rnor5.0
RGSC_v3.4	5	9,086,661 - 9,086,818	UniSTS	RGSC3.4
Celera	5	9,041,357 - 9,041,508	UniSTS
Cytogenetic Map	5	q11	UniSTS

RH142499

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	9,540,754 - 9,540,863 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	9,237,688 - 9,237,796	NCBI	Rnor6.0
Rnor_5.0	5	14,037,766 - 14,037,874	UniSTS	Rnor5.0
RGSC_v3.4	5	9,094,803 - 9,094,911	UniSTS	RGSC3.4
Celera	5	9,049,492 - 9,049,600	UniSTS
RH 3.4 Map	5	50.2	UniSTS
Cytogenetic Map	5	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_176857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB045378	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF289091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000009136 ⟹ ENSRNOP00000009136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	14,316,918 - 14,347,778 (+)	Ensembl
mRatBN7.2 Ensembl	5	9,534,129 - 9,562,040 (+)	Ensembl
Rnor_6.0 Ensembl	5	9,230,984 - 9,257,934 (+)	Ensembl

RefSeq Acc Id:

NM_176857 ⟹ NP_789827

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	14,317,083 - 14,343,724 (+)	NCBI
mRatBN7.2	5	9,534,247 - 9,560,889 (+)	NCBI
Rnor_6.0	5	9,231,180 - 9,257,821 (+)	NCBI
Rnor_5.0	5	14,031,258 - 14,057,899 (+)	NCBI
RGSC_v3.4	5	9,088,295 - 9,114,936 (+)	RGD
Celera	5	9,042,984 - 9,069,572 (+)	RGD

Sequence:

show sequence

CTGGTAGGGAAAGGAAAGCCATTCGCTCTGGGCCTGGACTAGACCTCGTCGGGCCGGCGGAGGT
CTGGCTATGTGCCTTTGAGGGTCGCTTGGGACGCAGAGCGAGAGCCGAGAGCGATGTCTCAGCC
GCCGCCGCCTCCTCCGCTGCCGCCGCCGCCGCCTCCCCCCGAGGCTCCGCAGACTTCGTCGTCC
CTGGCGGCGGCGGCTACTCCGGGGGGCCTTTCGAAACGAAGGGACCGGAGAATCCTTTCCGGGA
GCTGCCCGGATCCCAAGTGCCAGGCGCGGCTCTTCTTCCCGGCCTCAGGTTCTGTCAGCATCGA
GTGTACCGAGTGCGGACAGCGGCACGAGCAGCAACAGCTGCTGGGAGTGGAGGAGGTGACCGAC
CCGGACGTAGTGCTGCACAATCTGCTGCGGAACGCGCTACTCGGGGTGACGGGGGCTCCCAAGA
AGAACACGGAACTGGTAAAGGTGATGGGCCTCTCCAACTACCACTGCAAATTATTGTCGCCCAT
ATTGGCACGCTATGGAATGGACAAACAAACGGGCCGCGCCAAGCTTCTCCGGGACATGAACCAA
GGCGAACTGTTCGATTGCGCGTTACTCGGTGACCGGGCCTTCCTCATCGAACCAGAGCACGTCA
ACACAGTGGGCTATGGCAAGGACCGATCTGGAAGCCTCCTATATTTGCATGACACTCTCGAGGA
TATCAAACGGGCCAATAAAAGTCAAGAATGCCTTATTCCAGTGCATGTGGATGGGGATGGACAC
TGCCTAGTGCATGCTGTGTCTAGGGCTCTAGTAGGCCGAGAGCTCTTCTGGCATGCCCTGAGGG
AGAATCTGAAGCAGCACTTTCAGCAGCACCTAGCCCGATATCAAGCCCTGTTTCATGACTTTAT
TGATGCTGCAGAGTGGGAGGACATTATCAATGAATGTGACCCTCTGTTTGTGCCACCTGAAGGT
GTCCCCTTAGGCCTGAGGAATATCCACATATTTGGCCTTGCCAATGTGTTACATCGTCCCATAA
TTCTCTTAGATTCCCTCAGTGGCATGAGAAGCTCTGGTGATTATTCAGCCACCTTTCTACCTGG
GCTCATACCTGCAGAGAAGTGCACTGGGAGAGATGGTCATTTGAACAAGCCAATCTGTATTGCG
TGGAGTAGCTCTGGTAGAAACCATTATATTCCCTTGGTAGGCATAAAGGGGGCTGCCTTGCCCA
AACTACCCATGAATTTGCTACCTAAAGCATGGGGTGTGCCTCAGGACCTTATTAAAAAGTACAT
CAAGCTTGAGGAGGATGGTGGTTGTGTTATTGGAGGAGACAGAAGTTTGCAGGATAAGTACTTA
CTTAGGTTGGTTGCTGCTATGGAGGAAGTCTTTATGGACAAACATGGTATCCATCCTAGTTTGG
TTGCTGATGTACATCAGTATTTCTACAGAAGGACTGGGGTGATAGGAGTTCAGCCTGAGGAAGT
TACAGCAGCTGCTAAAAAAGCAGTAATGGATAATCGCCTTCACAAGTGTTTGCTTTGTGGTGCC
CTTTCTGAACTTCATGTCCCTCCTGAGTGGTTGGCTCCAGGAGGAAAACTGTATAACCTGGCAA
AAAGTACTCATGGACAGCTGAGGCCTGACAAAAATTACAGCTTTCCTTTAAACAATTTGGTTTG
TTCATATGATCCAGTGAAAGATGTTCTGTTACCAGACTATGGATTGAGTAATCTAACAGCTTGT
AATTGGTGCCATGGCACATCTGTGCGAAGAGTCAGAGGCGATGGCTCTATTGTATATTTGGATG
GAGACAGAACTAATTCTAGGTCTACTGGTGGCAAATGTGGTTGTGGATTCAAACACTTTTGGGA
AGGTAAAGAATATGACAACCTTCCAGAAGCTTTTCCTATCACTTTGGAGTGGGGAGGAAGAGTA
GTCAGAGAAACAGTATATTGGTTCCAGTATGAAAGTGATCCATCTTTGAATAGTAATGTTTATG
ATGTTGCAATGAAACTTGTTACCAAGCACTTTCCAGGTGAATTTGGGAGTGAGATCCTAGTTCA
GAAAGTTGTCCACACTATATTGCATCAGACTGCAAAAAAAAATCCTGACGATTACACTCCTGTA
AATATAGATGGTGCTCATGCTCAGAGAATTGGAGATGTGCAAGGACAAGAATTGGAGTCTCAGC
TACCAACTAAAATTATTCTTACTGGACAGAAAACAAAAACTTTGCACAAGGAAGAATTAAACAT
GAGTAAAACTGAAAGAACTATTCAACAGAACATCACAGAACAAGCTTCTGTGATGCAGAAACGG
AAAACAGAGAAATTAAAACAAGAGCAAAAGGGGCAACCCAGAACTGTTTCTCCAAGTACTATTC
GTGATGGGCCTTCATCTGCACCTGCCACCCCCACGAAGGCTCCCTACTCACCTACCACTTCTAA
GGAGAAGAAGATTCGCATAACAACTAATGATGGACGGCAGTCCATGGTTACCCTTAAGTCTTCA
ACAACCTTTTTTGAACTTCAGGAAAGTATAGCCAGAGAGTTCAACATTCCTCCATATTTACAGT
GTATTCGATATGGTTTTCCTCCTAAAGAGTTAATGCCACCCCAAGCAGGAATGGAAAAGGAGCC
AGTTCCTTTGCAGCATGGTGACAGAATTACCATAGAGATCTTAAAAGGCAAAGCAGAAGGTGGT
CCATCCACTGCTGCACACTCAGCCCACACTGTGAGACAAGAAGAGATTGCTGTTACTGGCAAGC
TGTCCTCCAAGGAACTTCAGGAGCAAGCTGACAAAGAAATGTATTCCTTGTGTCTTTTAGCAAC
ATTAATGGGAGAAGACGTGTGGTCTTATGCAAAGGGACTTCCTCACATGTTCCAGCAGGGTGGT
GTATTCTACAATATTATGAAGAAAACTATGGGCATGGCTGATGGCAAACATTGTACTTTTCCAC
ATCTACCTGGCAAAACCTTTGTTTATAATGCTTCTGAAGACAGACTGGAGTTGTGTGTCGATGC
CGCAGGACATTTCCCCATTGGTCCTGATGTTGAAGATTTAGTTAAAGAGGCTGTAAGTCAGGTT
CGAGCAGAGGCTACTACAAGAAGTAGGGAATCAAGCCCTTCACATGGGTTATTAAAACTAGGTA
GTGGTGGAGTAGTGAAAAAGAAGTCTGAGCAACTTCACAATGTAACTGCCTTTCAGGGGAAGGG
CCATTCTCTAGGAACTGCATCCAGTAACCCGCACATGGATCCCAGAGCTAGGGAAACTCTGGCT
GTAAGAAAGCATAATACAGGGACAGATTTTAGTAATAGTTCCATTAAAACAGAGCCTCCTGTGT
TCACAGCTGCTTCTAGTAATAGTGAGCTTATTCGAATAGCTCCTGGAGTGGTAACAATGAGAGA
TGGTAGGCAGATTGATCCCGATGTGGTTGAGGCCCAGCGAAAAAAATTGCAGGAAATGGTTTCT
TCTATTCAGGCATCAATGGACAAGCACTTGCGGGATCAAAGTACAGAGCAAACACCATCTGATC
TTTCTCAAAGAAAAGTAGAAGCTGTGAGTTCTTCTGTGAGGCCTGGGAATCTTCAGACTGGCTT
GCCTGAATCTTTTTCTTTAACTGGTGGCACTGAGAATTTGAATACTGAAACAACTGATAGTCGT
GTAGCAGATGTACTGGGAGCAGCATTTGCCACAAGGTCAAAAGCACAAAAAGAAAATTCCATGG
AGGAACCTGAAGAGATGGATAGTCAAGATGCTGAGACAACTAACACAACTGAGCCGATGGATCA
CTCTTGATTTAATTTAGAGGCTAATAAAGGCAGATGTTTATTGTGAATATGTAATATTTGTTGG
CTGGGCCACATAACTTGAGTAGTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_789827	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAQ14350	(Get FASTA)	NCBI Sequence Viewer
	BAC44841	(Get FASTA)	NCBI Sequence Viewer
	EDM11556	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000009136
	ENSRNOP00000009136.3
GenBank Protein	Q8CF97	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_789827 ⟸ NM_176857

- UniProtKB:

Q7TNK5 (UniProtKB/Swiss-Prot), Q8CF97 (UniProtKB/Swiss-Prot), A6JFG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSQPPPPPPLPPPPPPPEAPQTSSSLAAAATPGGLSKRRDRRILSGSCPDPKCQARLFFPASGS
VSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKL
LSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHD
TLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALF
HDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSAT
FLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLI
KKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQ
PEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLN
NLVCSYDPVKDVLLPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFK
HFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSE
ILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRIGDVQGQELESQLPTKIILTGQKTKTLHKE
ELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSP
TTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGM
EKEPVPLQHGDRITIEILKGKAEGGPSTAAHSAHTVRQEEIAVTGKLSSKELQEQADKEMYSLC
LLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLEL
CVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAF
QGKGHSLGTASSNPHMDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVV
TMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSTEQTPSDLSQRKVEAVSSSVRPGNL
QTGLPESFSLTGGTENLNTETTDSRVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTE
PMDHS

hide sequence

Ensembl Acc Id:

ENSRNOP00000009136 ⟸ ENSRNOT00000009136

Protein Domains

OTU

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CF97-F1-model_v2	AlphaFold	Q8CF97	1-1221	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693536

Promoter ID:

EPDNEW_R4061

Type:

initiation region

Name:

Vcpip1_1

Description:

valosin containing protein interacting protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	9,231,058 - 9,231,118	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708520	AgrOrtholog
BioCyc Gene	G2FUF-42198	BioCyc
Ensembl Genes	ENSRNOG00000006980	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000009136	ENTREZGENE
	ENSRNOT00000009136.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.90.70.80	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
InterPro	OTU1_Ubl	UniProtKB/Swiss-Prot
	OTU_dom	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
	VCIP135	UniProtKB/Swiss-Prot
	VCPIP1_N	UniProtKB/Swiss-Prot
KEGG Report	rno:286761	UniProtKB/Swiss-Prot
NCBI Gene	286761	ENTREZGENE
PANTHER	DEUBIQUITINATING PROTEIN VCPIP1	UniProtKB/Swiss-Prot
	PTHR14843	UniProtKB/Swiss-Prot
Pfam	OTU	UniProtKB/Swiss-Prot
	OTU1_UBXL	UniProtKB/Swiss-Prot
	VCIP135_N	UniProtKB/Swiss-Prot
PhenoGen	Vcpip1	PhenoGen
PROSITE	OTU	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000006980	RatGTEx
Superfamily-SCOP	SSF54236	UniProtKB/Swiss-Prot
UniProt	A6JFG0	ENTREZGENE, UniProtKB/TrEMBL
	Q7TNK5	ENTREZGENE
	Q8CF97	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q7TNK5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-03	Vcpip1	valosin containing protein interacting protein 1	Vcpip1	valosin containing protein (p97)/p47 complex interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Vcpip1	valosin containing protein (p97)/p47 complex interacting protein 1	Vcip135	valosin-containing protein (p97)/p47 complex-interacting protein 135	Symbol and Name updated	1299863	APPROVED
2005-07-08	Vcip135	valosin-containing protein (p97)/p47 complex-interacting protein 135		valosin-containing protein (p97)/p47 complex-interacting protein p135	Name updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI