Lancl1 (LanC like glutathione S-transferase 1) - Rat Genome Database

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Pathways
Gene: Lancl1 (LanC like glutathione S-transferase 1) Rattus norvegicus
Analyze
Symbol: Lancl1
Name: LanC like glutathione S-transferase 1
RGD ID: 69416
Description: Predicted to enable several functions, including SH3 domain binding activity; glutathione binding activity; and glutathione transferase activity. Predicted to be involved in cellular detoxification. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Orthologous to human LANCL1 (LanC like glutathione S-transferase 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 40 kDa erythrocyte membrane protein; glutathione S-transferase LANCL1; GPR69A; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC lantibiotic synthetase component C-like 1; LanC lantibiotic synthetase component C-like 1 (bacterial); LanC like 1; LanC-like 1; LanC-like 1(bacterial); lanC-like protein 1; MGC93999; p40
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,968,284 - 75,998,397 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl975,968,286 - 76,003,475 (-)EnsemblGRCr8
mRatBN7.2968,515,052 - 68,548,646 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,518,574 - 68,548,628 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx977,007,766 - 77,037,685 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0982,136,694 - 82,166,613 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,543,344 - 80,573,309 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0974,018,192 - 74,048,098 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl974,014,656 - 74,048,244 (-)Ensemblrn6Rnor6.0
Rnor_5.0973,260,328 - 73,293,876 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4965,799,079 - 65,828,986 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera965,997,618 - 66,027,525 (-)NCBICelera
RGSC_v3.1965,946,062 - 65,975,968 (-)NCBI
Cytogenetic Map9q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
plasma membrane  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of p40/GPR69A as a peripheral membrane protein related to the lantibiotic synthetase component C. Bauer H, etal., Biochem Biophys Res Commun 2000 Aug 18;275(1):69-74.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Characterization of rat LANCL1, a novel member of the lanthionine synthetase C-like protein family, highly expressed in testis and brain. Mayer H, etal., Gene 2001 May 16;269(1-2):73-80.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14514412   PMID:15082773   PMID:15489334   PMID:19528316   PMID:22120110   PMID:22891245   PMID:23376485   PMID:25158856   PMID:25931508  


Genomics

Comparative Map Data
Lancl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,968,284 - 75,998,397 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl975,968,286 - 76,003,475 (-)EnsemblGRCr8
mRatBN7.2968,515,052 - 68,548,646 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,518,574 - 68,548,628 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx977,007,766 - 77,037,685 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0982,136,694 - 82,166,613 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,543,344 - 80,573,309 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0974,018,192 - 74,048,098 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl974,014,656 - 74,048,244 (-)Ensemblrn6Rnor6.0
Rnor_5.0973,260,328 - 73,293,876 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4965,799,079 - 65,828,986 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera965,997,618 - 66,027,525 (-)NCBICelera
RGSC_v3.1965,946,062 - 65,975,968 (-)NCBI
Cytogenetic Map9q32NCBI
LANCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382210,431,251 - 210,477,584 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2210,427,131 - 210,477,652 (-)Ensemblhg38GRCh38
GRCh372211,295,975 - 211,341,483 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362211,004,220 - 211,049,676 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342211,121,481 - 211,166,937NCBI
Celera2205,064,000 - 205,109,528 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2203,142,033 - 203,187,544 (-)NCBIHuRef
CHM1_12211,302,098 - 211,347,624 (-)NCBICHM1_1
T2T-CHM13v2.02210,912,027 - 210,958,415 (-)NCBIT2T-CHM13v2.0
Lancl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39167,039,676 - 67,078,049 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl167,039,676 - 67,078,031 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38167,000,517 - 67,038,891 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl167,000,517 - 67,038,872 (-)Ensemblmm10GRCm38
MGSCv37167,047,091 - 67,085,439 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36166,933,725 - 66,972,073 (-)NCBIMGSCv36mm8
Celera167,518,602 - 67,556,787 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.75NCBI
Lancl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,055,412 - 5,087,629 (+)Ensembl
ChiLan1.0NW_0049554575,055,774 - 5,087,570 (+)NCBIChiLan1.0ChiLan1.0
LANCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213113,054,927 - 113,100,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B113,069,907 - 113,115,173 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,689,353 - 97,735,403 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B216,090,580 - 216,136,826 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B216,090,580 - 216,136,826 (-)EnsemblpanPan2panpan1.1
LANCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13718,209,162 - 18,246,100 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3718,212,137 - 18,246,354 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3719,093,044 - 19,127,151 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03718,150,458 - 18,184,557 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,147,382 - 18,184,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,102,975 - 18,137,066 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03718,065,451 - 18,099,512 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,080,246 - 18,114,053 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lancl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,675,567 - 166,708,402 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365865,917,413 - 5,952,952 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365865,917,470 - 5,950,101 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LANCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15113,111,370 - 113,149,050 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115113,111,427 - 113,149,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LANCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11096,144,156 - 96,191,023 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1096,144,541 - 96,191,030 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040103,172,642 - 103,217,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lancl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247655,730,866 - 5,767,058 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247655,731,236 - 5,766,907 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lancl1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14139,819,041 - 139,856,254 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lancl1
99 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:71
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000018293
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018293   ⟹   ENSRNOP00000018293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,968,286 - 76,003,475 (-)Ensembl
mRatBN7.2 Ensembl968,518,576 - 68,548,277 (-)Ensembl
Rnor_6.0 Ensembl974,014,656 - 74,048,244 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl974,030,726 - 74,048,244 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095161   ⟹   ENSRNOP00000085697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,968,286 - 75,998,191 (-)Ensembl
mRatBN7.2 Ensembl968,518,574 - 68,548,628 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108238   ⟹   ENSRNOP00000084242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl975,968,286 - 75,998,191 (-)Ensembl
mRatBN7.2 Ensembl968,519,177 - 68,548,628 (-)Ensembl
RefSeq Acc Id: NM_053723   ⟹   NP_446175
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,968,284 - 75,998,191 (-)NCBI
mRatBN7.2968,518,574 - 68,548,479 (-)NCBI
Rnor_6.0974,018,192 - 74,048,098 (-)NCBI
Rnor_5.0973,260,328 - 73,293,876 (+)NCBI
RGSC_v3.4965,799,079 - 65,828,986 (-)RGD
Celera965,997,618 - 66,027,525 (-)RGD
Sequence:
RefSeq Acc Id: XM_039082904   ⟹   XP_038938832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,968,284 - 75,998,366 (-)NCBI
mRatBN7.2968,515,052 - 68,548,646 (-)NCBI
RefSeq Acc Id: XM_039082905   ⟹   XP_038938833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,968,284 - 75,998,363 (-)NCBI
mRatBN7.2968,515,052 - 68,548,641 (-)NCBI
RefSeq Acc Id: XM_063266534   ⟹   XP_063122604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8975,968,284 - 75,998,397 (-)NCBI
RefSeq Acc Id: NP_446175   ⟸   NM_053723
- UniProtKB: Q9ER29 (UniProtKB/Swiss-Prot),   Q9QX69 (UniProtKB/Swiss-Prot),   A6KFE1 (UniProtKB/TrEMBL),   A0A8I6A0Q6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018293   ⟸   ENSRNOT00000018293
RefSeq Acc Id: XP_038938832   ⟸   XM_039082904
- Peptide Label: isoform X1
- UniProtKB: Q9QX69 (UniProtKB/Swiss-Prot),   Q9ER29 (UniProtKB/Swiss-Prot),   A6KFE1 (UniProtKB/TrEMBL),   A0A8I6A0Q6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938833   ⟸   XM_039082905
- Peptide Label: isoform X1
- UniProtKB: Q9QX69 (UniProtKB/Swiss-Prot),   Q9ER29 (UniProtKB/Swiss-Prot),   A6KFE1 (UniProtKB/TrEMBL),   A0A8I6A0Q6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084242   ⟸   ENSRNOT00000108238
Ensembl Acc Id: ENSRNOP00000085697   ⟸   ENSRNOT00000095161
RefSeq Acc Id: XP_063122604   ⟸   XM_063266534
- Peptide Label: isoform X1
- UniProtKB: Q9QX69 (UniProtKB/Swiss-Prot),   Q9ER29 (UniProtKB/Swiss-Prot),   A6KFE1 (UniProtKB/TrEMBL),   A0A8I6A0Q6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QX69-F1-model_v2 AlphaFold Q9QX69 1-399 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696727
Promoter ID:EPDNEW_R7252
Type:initiation region
Name:Lancl1_2
Description:LanC like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7253  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0974,048,101 - 74,048,161EPDNEW
RGD ID:13696728
Promoter ID:EPDNEW_R7253
Type:initiation region
Name:Lancl1_1
Description:LanC like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7252  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0974,048,247 - 74,048,307EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69416 AgrOrtholog
BioCyc Gene G2FUF-27281 BioCyc
BioCyc Pathway PWY-4061 [glutathione-mediated detoxification I] BioCyc
  PWY-7112 [4-hydroxy-2-nonenal detoxification] BioCyc
BioCyc Pathway Image PWY-4061 BioCyc
  PWY-7112 BioCyc
Ensembl Genes ENSRNOG00000013557 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000018293 ENTREZGENE
  ENSRNOT00000108238 ENTREZGENE
Gene3D-CATH 1.50.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7115423 IMAGE-MGC_LOAD
InterPro 6hp_glycosidase-like_sf UniProtKB/Swiss-Prot
  LANC-like UniProtKB/Swiss-Prot
  LanC-like_prot_euk UniProtKB/Swiss-Prot
KEGG Report rno:114515 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93999 IMAGE-MGC_LOAD
NCBI Gene 114515 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE LANCL1 UniProtKB/Swiss-Prot
  LANC-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam LANC_like UniProtKB/Swiss-Prot
PhenoGen Lancl1 PhenoGen
PRINTS LANCEUKARYTE UniProtKB/Swiss-Prot
  LANCSUPER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013557 RatGTEx
SMART LANC_like UniProtKB/Swiss-Prot
Superfamily-SCOP LanC-like UniProtKB/Swiss-Prot
UniProt A0A8I5ZYR5_RAT UniProtKB/TrEMBL
  A0A8I6A0Q6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QA50_RAT UniProtKB/TrEMBL
  A6KFE1 ENTREZGENE, UniProtKB/TrEMBL
  LANC1_RAT UniProtKB/Swiss-Prot
  Q9ER29 ENTREZGENE
  Q9QX69 ENTREZGENE
UniProt Secondary Q9ER29 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-03 Lancl1  LanC like glutathione S-transferase 1  Lancl1  LanC like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Lancl1  LanC like 1  Lancl1  LanC lantibiotic synthetase component C-like 1 (bacterial)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-11 Lancl1  LanC lantibiotic synthetase component C-like 1 (bacterial)  Lancl1  lanC (bacterial lantibiotic synthetase component C)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Lancl1  LanC-like 1(bacterial)      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the cytoplasmic side of the membrane 69378
gene_process involved in the modification and transport of antimicrobial lantibiotics 68710
gene_process involved in the modification and transport of antimicrobial lantibiotics 69378