Prim2 (DNA primase subunit 2) - Rat Genome Database

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Pathways
Gene: Prim2 (DNA primase subunit 2) Rattus norvegicus
Analyze
Symbol: Prim2
Name: DNA primase subunit 2
RGD ID: 631433
Description: Predicted to enable 4 iron, 4 sulfur cluster binding activity and DNA/RNA hybrid binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in DNA replication initiation and DNA replication, synthesis of primer. Predicted to be part of alpha DNA polymerase:primase complex. Orthologous to human PRIM2 (DNA primase subunit 2); PARTICIPATES IN DNA replication pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA polymerase alpha subunit III (primase); DNA primase 58 kDa subunit; DNA primase large subunit; DNA primase, p58 subunit; p58; Pola3; primase (DNA) subunit 2; primase, DNA, polypeptide 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,188,350 - 43,400,482 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl943,188,350 - 43,398,990 (-)EnsemblGRCr8
mRatBN7.2935,692,376 - 35,904,521 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl935,692,376 - 35,903,030 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx944,192,519 - 44,401,401 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,320,479 - 49,532,594 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,602,394 - 47,814,513 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,535,435 - 38,745,058 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,536,920 - 38,745,099 (+)Ensemblrn6Rnor6.0
Rnor_5.0938,215,946 - 38,424,424 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4932,206,274 - 32,424,970 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera933,486,356 - 33,697,667 (-)NCBICelera
RGSC_v3.1932,207,990 - 32,415,542 (-)NCBI
Cytogenetic Map9q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2-butoxyethanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
auramine O  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
equol  (ISO)
fulvestrant  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glutathione  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-Nitrosopyrrolidine  (ISO)
nitric oxide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex. Popanda O, etal., Mol Carcinog 2001 Aug;31(4):171-83.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Prim2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,188,350 - 43,400,482 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl943,188,350 - 43,398,990 (-)EnsemblGRCr8
mRatBN7.2935,692,376 - 35,904,521 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl935,692,376 - 35,903,030 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx944,192,519 - 44,401,401 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,320,479 - 49,532,594 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,602,394 - 47,814,513 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,535,435 - 38,745,058 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,536,920 - 38,745,099 (+)Ensemblrn6Rnor6.0
Rnor_5.0938,215,946 - 38,424,424 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4932,206,274 - 32,424,970 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera933,486,356 - 33,697,667 (-)NCBICelera
RGSC_v3.1932,207,990 - 32,415,542 (-)NCBI
Cytogenetic Map9q21NCBI
PRIM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,221,540 - 57,646,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl657,314,805 - 57,646,855 (+)Ensemblhg38GRCh38
GRCh37657,179,603 - 57,513,376 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,290,381 - 57,621,335 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34657,290,380 - 57,621,334NCBI
Celera658,845,527 - 58,907,120 (+)NCBICelera
Cytogenetic Map6p11.2NCBI
HuRef521,733,697 - 21,771,156 (-)NCBIHuRef
HuRef657,016,307 - 57,236,736 (+)NCBIHuRef
CHM1_1657,179,974 - 57,645,053 (+)NCBICHM1_1
T2T-CHM13v2.0657,060,566 - 57,485,715 (+)NCBIT2T-CHM13v2.0
Prim2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,492,889 - 33,708,867 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,492,891 - 33,708,876 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38133,453,808 - 33,669,808 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,453,810 - 33,669,795 (-)Ensemblmm10GRCm38
MGSCv37133,510,656 - 33,726,603 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36133,398,357 - 33,614,304 (-)NCBIMGSCv36mm8
Celera133,228,568 - 33,444,813 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.7NCBI
Prim2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555022,647,462 - 2,898,919 (-)Ensembl
ChiLan1.0NW_0049555022,642,328 - 2,898,919 (-)NCBIChiLan1.0ChiLan1.0
PRIM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,692,575 - 72,119,835 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,668,942 - 68,000,220 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,875,331 - 56,884,118 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,503,286 - 58,514,832 (+)NCBIPanPan1.1PanPan1.1panPan2
PRIM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11224,504,202 - 24,811,942 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1224,504,700 - 24,811,924 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1224,432,446 - 24,739,676 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01225,042,105 - 25,349,960 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1225,042,169 - 25,349,957 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11224,539,462 - 24,846,864 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01224,641,103 - 24,948,387 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01224,772,113 - 25,079,798 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Prim2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,962,253 - 60,223,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364763,737,061 - 3,996,910 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364763,736,663 - 3,997,936 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRIM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,274,627 - 28,631,514 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1728,274,626 - 28,566,633 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2732,750,198 - 33,023,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRIM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11713,995,488 - 14,304,161 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1713,995,401 - 14,304,156 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605820,315,866 - 20,455,696 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prim2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475319,014,579 - 19,447,714 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Prim2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14109,723,993 - 109,922,650 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Prim2
1586 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:342
Count of miRNA genes:122
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000016828, ENSRNOT00000060452
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat

Markers in Region
RH133423  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2935,692,592 - 35,692,776 (-)MAPPERmRatBN7.2
Rnor_6.0938,744,658 - 38,744,841NCBIRnor6.0
Rnor_5.0938,424,024 - 38,424,207UniSTSRnor5.0
RGSC_v3.4932,206,482 - 32,206,665UniSTSRGSC3.4
Celera933,486,564 - 33,486,747UniSTS
RH 3.4 Map9355.89UniSTS
Cytogenetic Map9q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010054582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ011607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016828   ⟹   ENSRNOP00000016828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl943,188,350 - 43,391,478 (-)Ensembl
mRatBN7.2 Ensembl935,692,376 - 35,895,497 (-)Ensembl
Rnor_6.0 Ensembl938,544,398 - 38,745,099 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000060452   ⟹   ENSRNOP00000057197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl943,188,362 - 43,398,990 (-)Ensembl
mRatBN7.2 Ensembl935,692,388 - 35,903,030 (-)Ensembl
Rnor_6.0 Ensembl938,536,920 - 38,745,048 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000170080   ⟹   ENSRNOP00000104632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl943,188,350 - 43,391,487 (-)Ensembl
RefSeq Acc Id: NM_001024762   ⟹   NP_001019933
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,359 - 43,400,454 (-)NCBI
mRatBN7.2935,692,385 - 35,904,494 (-)NCBI
Rnor_6.0938,535,456 - 38,745,049 (+)NCBI
Rnor_5.0938,215,946 - 38,424,424 (+)NCBI
RGSC_v3.4932,206,274 - 32,424,970 (-)RGD
Celera933,486,356 - 33,697,667 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399183   ⟹   NP_001386112
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,391,478 (-)NCBI
mRatBN7.2935,692,376 - 35,895,518 (-)NCBI
RefSeq Acc Id: NM_001399184   ⟹   NP_001386113
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,391,478 (-)NCBI
mRatBN7.2935,692,376 - 35,895,518 (-)NCBI
RefSeq Acc Id: XM_006244690   ⟹   XP_006244752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,391,467 (-)NCBI
mRatBN7.2935,692,376 - 35,895,520 (-)NCBI
Rnor_6.0938,544,376 - 38,745,058 (+)NCBI
Rnor_5.0938,215,946 - 38,424,424 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244691   ⟹   XP_006244753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,400,472 (-)NCBI
mRatBN7.2935,692,376 - 35,904,496 (-)NCBI
Rnor_6.0938,535,435 - 38,745,058 (+)NCBI
Rnor_5.0938,215,946 - 38,424,424 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596335   ⟹   XP_017451824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,400,482 (-)NCBI
mRatBN7.2935,692,376 - 35,904,496 (-)NCBI
Rnor_6.0938,535,435 - 38,745,058 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083201   ⟹   XP_038939129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,400,472 (-)NCBI
mRatBN7.2935,692,376 - 35,904,496 (-)NCBI
RefSeq Acc Id: XM_039083202   ⟹   XP_038939130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,398,623 (-)NCBI
mRatBN7.2935,692,376 - 35,904,521 (-)NCBI
RefSeq Acc Id: XM_039083205   ⟹   XP_038939133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,390,434 (-)NCBI
mRatBN7.2935,692,376 - 35,894,659 (-)NCBI
RefSeq Acc Id: XM_039083206   ⟹   XP_038939134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,338,069 (-)NCBI
mRatBN7.2935,692,376 - 35,842,105 (-)NCBI
RefSeq Acc Id: XM_039083207   ⟹   XP_038939135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,260,785 (-)NCBI
mRatBN7.2935,692,376 - 35,764,559 (-)NCBI
RefSeq Acc Id: XM_063266877   ⟹   XP_063122947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,188,350 - 43,374,795 (-)NCBI
RefSeq Acc Id: XR_010054582
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8943,247,372 - 43,400,476 (-)NCBI
RefSeq Acc Id: NP_001019933   ⟸   NM_001024762
- Peptide Label: isoform 2
- UniProtKB: Q4V8C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244753   ⟸   XM_006244691
- Peptide Label: isoform X1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244752   ⟸   XM_006244690
- Peptide Label: isoform X1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451824   ⟸   XM_017596335
- Peptide Label: isoform X1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057197   ⟸   ENSRNOT00000060452
Ensembl Acc Id: ENSRNOP00000016828   ⟸   ENSRNOT00000016828
RefSeq Acc Id: XP_038939130   ⟸   XM_039083202
- Peptide Label: isoform X1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939129   ⟸   XM_039083201
- Peptide Label: isoform X1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939133   ⟸   XM_039083205
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038939134   ⟸   XM_039083206
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038939135   ⟸   XM_039083207
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001386113   ⟸   NM_001399184
- Peptide Label: isoform 1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386112   ⟸   NM_001399183
- Peptide Label: isoform 1
- UniProtKB: O89044 (UniProtKB/Swiss-Prot),   A6IN89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122947   ⟸   XM_063266877
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000104632   ⟸   ENSRNOT00000170080

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O89044-F1-model_v2 AlphaFold O89044 1-507 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696599
Promoter ID:EPDNEW_R7118
Type:multiple initiation site
Name:Prim2_1
Description:DNA primase subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0938,544,413 - 38,544,473EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631433 AgrOrtholog
BioCyc Gene G2FUF-27880 BioCyc
Ensembl Genes ENSRNOG00000012486 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016828 ENTREZGENE
  ENSRNOT00000016828.9 UniProtKB/Swiss-Prot
  ENSRNOT00000060452 ENTREZGENE
  ENSRNOT00000170080 ENTREZGENE
Gene3D-CATH 1.20.930.80 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7456950 IMAGE-MGC_LOAD
InterPro DNA_primase_lsu_euk UniProtKB/Swiss-Prot
  DNA_primase_lsu_euk/arc UniProtKB/Swiss-Prot
MGC_CLONE MGC:114515 IMAGE-MGC_LOAD
NCBI Gene 301323 ENTREZGENE
PANTHER DNA PRIMASE LARGE SUBUNIT UniProtKB/Swiss-Prot
  PTHR10537 UniProtKB/Swiss-Prot
Pfam DNA_primase_lrg UniProtKB/Swiss-Prot
PhenoGen Prim2 PhenoGen
PIRSF DNA_primase_large_subunit UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012486 RatGTEx
Superfamily-SCOP PriB N-terminal domain-like UniProtKB/Swiss-Prot
UniProt A0ABK0L4W8_RAT UniProtKB/TrEMBL
  A6IN89 ENTREZGENE, UniProtKB/TrEMBL
  O89044 ENTREZGENE, UniProtKB/Swiss-Prot
  Q4V8C0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-22 Prim2  DNA primase subunit 2  Prim2  primase (DNA) subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-08-29 Prim2  primase (DNA) subunit 2  Prim2  primase, DNA, polypeptide 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Prim2  primase, DNA, polypeptide 2  Prim2  DNA primase, p58 subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Prim2  DNA primase, p58 subunit  Pola3  DNA polymerase alpha subunit III (primase)  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED