Slu7 (spliceosome associated SLU7) - Rat Genome Database

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Gene: Slu7 (spliceosome associated SLU7) Rattus norvegicus
Analyze
Symbol: Slu7
Name: spliceosome associated SLU7 (Ensembl:SLU7 homolog, splicing factor)
RGD ID: 631432
Description: Predicted to enable pre-mRNA 3'-splice site binding activity; second spliceosomal transesterification activity; and zinc ion binding activity. Predicted to be involved in cellular response to heat; intracellular protein transport; and mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of catalytic step 2 spliceosome and small nuclear ribonucleoprotein complex. Orthologous to human SLU7 (SLU7 homolog, splicing factor); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA segment, Chr 11, ERATO Doi 730, expressed; DNA segment, Chr 3, Brigham & Womens Genetics 0878 expressed; LOC303057; pre-mRNA-splicing factor SLU7; similar to step II splicing factor SLU7; SLU7 homolog, splicing factor; SLU7 splicing factor homolog; SLU7 splicing factor homolog (S. cerevisiae); step II splicing factor SLU7; step II splicing factor SLU7 (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81028,406,908 - 28,425,253 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1028,409,846 - 28,425,250 (+)EnsemblGRCr8
mRatBN7.21027,908,325 - 27,923,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1027,908,396 - 27,923,349 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1032,668,805 - 32,683,754 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0101,207,188 - 1,222,137 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01027,639,304 - 27,654,247 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01029,029,556 - 29,044,919 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1029,029,590 - 29,044,583 (+)Ensemblrn6Rnor6.0
Rnor_5.01028,871,433 - 28,886,835 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41028,536,630 - 28,551,427 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1027,401,434 - 27,416,356 (+)NCBICelera
RGSC_v3.11028,537,678 - 28,550,757 (+)NCBI
Cytogenetic Map10q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
catalytic step 2 spliceosome  (IEA,ISO)
cytoplasm  (IEA,ISO,ISS)
nuclear speck  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)
small nuclear ribonucleoprotein complex  (IEA,ISO,ISS)
spliceosomal complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The RNA splicing factor hSlu7 is required for correct 3' splice-site choice. Chua K and Reed R, Nature 1999 Nov 11;402(6758):207-10.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. A day in the life of the spliceosome. Matera AG and Wang Z, Nat Rev Mol Cell Biol. 2014 Feb;15(2):108-21. doi: 10.1038/nrm3742.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus. Shomron N, etal., Mol Biol Cell 2004 Aug;15(8):3782-95. Epub 2004 Jun 04.
Additional References at PubMed
PMID:9478977   PMID:10197984   PMID:11991638   PMID:12477932   PMID:15728250   PMID:19946888   PMID:21122810  


Genomics

Comparative Map Data
Slu7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81028,406,908 - 28,425,253 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1028,409,846 - 28,425,250 (+)EnsemblGRCr8
mRatBN7.21027,908,325 - 27,923,784 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1027,908,396 - 27,923,349 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1032,668,805 - 32,683,754 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0101,207,188 - 1,222,137 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01027,639,304 - 27,654,247 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01029,029,556 - 29,044,919 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1029,029,590 - 29,044,583 (+)Ensemblrn6Rnor6.0
Rnor_5.01028,871,433 - 28,886,835 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41028,536,630 - 28,551,427 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1027,401,434 - 27,416,356 (+)NCBICelera
RGSC_v3.11028,537,678 - 28,550,757 (+)NCBI
Cytogenetic Map10q21NCBI
SLU7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385160,401,641 - 160,419,081 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5160,401,641 - 160,421,711 (-)Ensemblhg38GRCh38
GRCh375159,828,648 - 159,846,088 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365159,761,226 - 159,778,746 (-)NCBIBuild 36Build 36hg18NCBI36
Celera5155,861,110 - 155,878,652 (-)NCBICelera
Cytogenetic Map5q33.3NCBI
HuRef5154,922,340 - 154,939,594 (-)NCBIHuRef
CHM1_15159,261,546 - 159,279,087 (-)NCBICHM1_1
T2T-CHM13v2.05160,930,130 - 160,947,593 (-)NCBIT2T-CHM13v2.0
Slu7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,324,550 - 43,338,809 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1143,324,571 - 43,338,808 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381143,433,726 - 43,447,982 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,433,744 - 43,447,981 (+)Ensemblmm10GRCm38
MGSCv371143,247,233 - 43,261,483 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361143,277,154 - 43,291,404 (+)NCBIMGSCv36mm8
Celera1148,062,245 - 48,076,494 (+)NCBICelera
Cytogenetic Map11B1.1NCBI
cM Map1125.68NCBI
Slu7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540814,267,369 - 14,288,213 (-)Ensembl
ChiLan1.0NW_00495540814,268,958 - 14,288,114 (-)NCBIChiLan1.0ChiLan1.0
SLU7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24155,587,032 - 155,604,972 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15153,726,578 - 153,744,518 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05155,792,494 - 155,810,474 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15162,486,743 - 162,504,316 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5162,486,743 - 162,504,316 (-)EnsemblpanPan2panpan1.1
SLU7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1450,314,063 - 50,328,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl450,314,086 - 50,327,733 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha450,209,676 - 50,224,618 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0450,749,579 - 50,764,516 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl450,748,743 - 50,764,508 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1450,557,999 - 50,572,951 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0450,681,739 - 50,696,726 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0451,202,029 - 51,216,993 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slu7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213104,723,568 - 104,730,569 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365153,168,838 - 3,178,588 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365153,172,962 - 3,179,915 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLU7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1663,118,733 - 63,136,640 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11663,118,426 - 63,145,655 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21668,469,349 - 68,507,713 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLU7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12362,761,466 - 62,778,613 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2362,764,335 - 62,778,910 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603414,825,845 - 14,843,018 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slu7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473329,146,579 - 29,162,074 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473329,147,329 - 29,161,687 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Slu7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1926,260,004 - 26,275,261 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slu7
121 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:239
Count of miRNA genes:164
Interacting mature miRNAs:183
Transcripts:ENSRNOT00000005132
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum immunoglobulin E level (CMO:0002101)102342212132490778Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005132   ⟹   ENSRNOP00000005132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1028,409,846 - 28,425,250 (+)Ensembl
mRatBN7.2 Ensembl1027,908,396 - 27,923,349 (+)Ensembl
Rnor_6.0 Ensembl1029,029,590 - 29,044,583 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088322   ⟹   ENSRNOP00000071959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1027,908,396 - 27,923,349 (+)Ensembl
Rnor_6.0 Ensembl1029,033,989 - 29,044,083 (+)Ensembl
RefSeq Acc Id: NM_001100550   ⟹   NP_001094020
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81028,409,865 - 28,424,818 (+)NCBI
mRatBN7.21027,908,396 - 27,923,349 (+)NCBI
Rnor_6.01029,029,556 - 29,044,508 (+)NCBI
Rnor_5.01028,871,433 - 28,886,835 (+)NCBI
RGSC_v3.41028,536,630 - 28,551,427 (+)RGD
Celera1027,401,434 - 27,416,356 (+)RGD
Sequence:
RefSeq Acc Id: XM_008767642   ⟹   XP_008765864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81028,409,782 - 28,425,253 (+)NCBI
mRatBN7.21027,908,325 - 27,923,784 (+)NCBI
Rnor_6.01029,033,143 - 29,044,919 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063268962   ⟹   XP_063125032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81028,410,043 - 28,425,253 (+)NCBI
RefSeq Acc Id: XM_063268963   ⟹   XP_063125033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81028,406,908 - 28,425,253 (+)NCBI
RefSeq Acc Id: NP_001094020   ⟸   NM_001100550
- UniProtKB: Q80ZG5 (UniProtKB/Swiss-Prot),   Q6P6G1 (UniProtKB/Swiss-Prot),   A0A0G2K1S0 (UniProtKB/TrEMBL),   B0BNL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765864   ⟸   XM_008767642
- Peptide Label: isoform X1
- UniProtKB: Q80ZG5 (UniProtKB/Swiss-Prot),   Q6P6G1 (UniProtKB/Swiss-Prot),   A0A0G2K1S0 (UniProtKB/TrEMBL),   B0BNL0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005132   ⟸   ENSRNOT00000005132
Ensembl Acc Id: ENSRNOP00000071959   ⟸   ENSRNOT00000088322
RefSeq Acc Id: XP_063125033   ⟸   XM_063268963
- Peptide Label: isoform X1
- UniProtKB: Q80ZG5 (UniProtKB/Swiss-Prot),   Q6P6G1 (UniProtKB/Swiss-Prot),   B0BNL0 (UniProtKB/TrEMBL),   A0A0G2K1S0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125032   ⟸   XM_063268962
- Peptide Label: isoform X1
- UniProtKB: Q80ZG5 (UniProtKB/Swiss-Prot),   Q6P6G1 (UniProtKB/Swiss-Prot),   B0BNL0 (UniProtKB/TrEMBL),   A0A0G2K1S0 (UniProtKB/TrEMBL)
Protein Domains
Pre-mRNA-splicing factor SLU7

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80ZG5-F1-model_v2 AlphaFold Q80ZG5 1-586 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697112
Promoter ID:EPDNEW_R7637
Type:multiple initiation site
Name:Slu7_1
Description:SLU7 homolog, splicing factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01029,029,556 - 29,029,616EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631432 AgrOrtholog
BioCyc Gene G2FUF-25454 BioCyc
Ensembl Genes ENSRNOG00000003822 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005132 ENTREZGENE
  ENSRNOT00000005132.6 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6890616 IMAGE-MGC_LOAD
  IMAGE:7938574 IMAGE-MGC_LOAD
InterPro Slu7_dom UniProtKB/Swiss-Prot
  Splicing_factor_SLU7 UniProtKB/Swiss-Prot
KEGG Report rno:303057 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188474 IMAGE-MGC_LOAD
  MGC:73016 IMAGE-MGC_LOAD
NCBI Gene Slu7 ENTREZGENE
PANTHER PRE-MRNA-SPLICING FACTOR SLU7 UniProtKB/Swiss-Prot
  PTHR12942 UniProtKB/Swiss-Prot
Pfam Slu7 UniProtKB/Swiss-Prot
PhenoGen Slu7 PhenoGen
RatGTEx ENSRNOG00000003822 RatGTEx
UniProt A0A0G2K1S0 ENTREZGENE
  B0BNL0 ENTREZGENE, UniProtKB/TrEMBL
  Q6P6G1 ENTREZGENE
  Q80ZG5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6P6G1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Slu7  spliceosome associated SLU7  Slu7  SLU7 homolog, splicing factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-13 Slu7  SLU7 homolog, splicing factor  Slu7  SLU7 splicing factor homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-09-21 Slu7  SLU7 splicing factor homolog (S. cerevisiae)  LOC303057  similar to step II splicing factor SLU7; DNA segment, Chr 11, ERATO Doi 730, expressed; DNA segment, Chr 3, Brigham & Womens Genetics 0878 expressed  Data merged from RGD:735176 737654 APPROVED
2008-02-25 Slu7  SLU7 splicing factor homolog (S. cerevisiae)  Slu7  step II splicing factor SLU7 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-28 LOC303057        Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-11 Slc1a7  step II splicing factor SLU7 (S. cerevisiae)  Slu7  step II splicing factor SLU7  Name updated to reflect Human and Mouse nomenclature 625702 APPROVED