Gene: Sytl5 (synaptotagmin-like 5) Rattus norvegicus
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Symbol:
Sytl5
Name:
synaptotagmin-like 5
RGD ID:
631342
Description:
Predicted to enable neurexin family protein binding activity. Predicted to be involved in exocytosis. Predicted to be located in membrane. Predicted to be active in exocytic vesicle and plasma membrane. Orthologous to human SYTL5 (synaptotagmin like 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
synaptotagmin 15; synaptotagmin-like protein 5
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SYTL5 (synaptotagmin like 5)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Sytl5 (synaptotagmin-like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Sytl5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SYTL5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SYTL5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Sytl5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SYTL5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
SYTL5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Sytl5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Sytl5 (synaptotagmin like 5)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SYTL5 (synaptotagmin like 5)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Sytl5 (synaptotagmin-like 5)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
sytl5 (synaptotagmin-like 5)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
btsz
Alliance
DIOPT (OrthoFinder|OrthoInspector|PANTHER)
Drosophila melanogaster (fruit fly):
btsz
Alliance
DIOPT (OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
sytl5
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 15,461,215 - 15,702,660 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl X 15,460,472 - 15,550,471 (-) Ensembl GRCr8 mRatBN7.2 X 12,775,529 - 13,030,134 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 12,788,698 - 13,030,175 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx X 12,980,058 - 13,068,810 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 16,476,998 - 16,565,752 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 12,733,565 - 12,822,327 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 13,857,669 - 14,109,592 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 14,019,961 - 14,109,568 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 X 14,642,886 - 14,891,896 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 X 24,945,436 - 25,034,025 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera X 13,398,414 - 13,486,944 (-) NCBI Celera RGSC_v3.1 X 25,059,892 - 25,087,494 (-) NCBI Cytogenetic Map X q12 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Sytl5 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Sytl5 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Sytl5 Rat 17beta-estradiol increases expression ISO SYTL5 (Homo sapiens) 6480464 Estradiol results in increased expression of SYTL5 mRNA CTD PMID:19167446|PMID:21185374|PMID:24758408|PMID:31614463 Sytl5 Rat 17beta-estradiol decreases expression ISO Sytl5 (Mus musculus) 6480464 Estradiol results in decreased expression of SYTL5 mRNA CTD PMID:39298647 Sytl5 Rat 17beta-estradiol multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of SYTL5 mRNA; [Estradiol co-treated more ... CTD PMID:20404318|PMID:20660070|PMID:24758408 Sytl5 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Sytl5 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Sytl5 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Sytl5 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Sytl5 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Sytl5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SYTL5 promoter] CTD PMID:19654925 Sytl5 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SYTL5 mRNA CTD PMID:32109520 Sytl5 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Sytl5 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Sytl5 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SYTL5 mRNA CTD PMID:32119087 Sytl5 Rat 4,4'-sulfonyldiphenol decreases expression ISO Sytl5 (Mus musculus) 6480464 bisphenol S results in decreased expression of SYTL5 mRNA CTD PMID:39298647 Sytl5 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SYTL5 mRNA CTD PMID:24780913 Sytl5 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SYTL5 mRNA CTD PMID:31881176 Sytl5 Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of SYTL5 mRNA CTD PMID:28959563 Sytl5 Rat aflatoxin B1 decreases methylation ISO SYTL5 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of SYTL5 gene CTD PMID:27153756 Sytl5 Rat all-trans-retinoic acid increases expression ISO SYTL5 (Homo sapiens) 6480464 Tretinoin results in increased expression of SYTL5 mRNA CTD PMID:21934132|PMID:23830798 Sytl5 Rat all-trans-retinoic acid multiple interactions ISO Sytl5 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SYTL5 mRNA CTD PMID:36189433 Sytl5 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SYTL5 mRNA CTD PMID:16483693 Sytl5 Rat benzo[a]pyrene increases methylation ISO SYTL5 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of SYTL5 3' UTR; Benzo(a)pyrene results in increased methylation of more ... CTD PMID:27901495 Sytl5 Rat benzo[a]pyrene decreases expression ISO SYTL5 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of SYTL5 mRNA CTD PMID:32234424 Sytl5 Rat bis(2-ethylhexyl) phthalate increases expression ISO SYTL5 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of SYTL5 mRNA CTD PMID:31163220 Sytl5 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SYTL5 mRNA CTD PMID:25181051 Sytl5 Rat buta-1,3-diene increases expression ISO Sytl5 (Mus musculus) 6480464 1,3-butadiene results in increased expression of SYTL5 mRNA CTD PMID:29038090 Sytl5 Rat cadmium atom increases expression ISO SYTL5 (Homo sapiens) 6480464 Cadmium results in increased expression of SYTL5 mRNA CTD PMID:24376830 Sytl5 Rat carbamazepine affects expression ISO SYTL5 (Homo sapiens) 6480464 Carbamazepine affects the expression of SYTL5 mRNA CTD PMID:25979313 Sytl5 Rat carbon nanotube decreases expression ISO Sytl5 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of SYTL5 mRNA CTD PMID:25620056 Sytl5 Rat cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of SYTL5 mRNA CTD PMID:18500788 Sytl5 Rat CGP 52608 multiple interactions ISO SYTL5 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SYTL5 gene] CTD PMID:28238834 Sytl5 Rat coumestrol multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SYTL5 mRNA; [Coumestrol co-treated with resveratrol] more ... CTD PMID:19167446 Sytl5 Rat coumestrol increases expression ISO SYTL5 (Homo sapiens) 6480464 Coumestrol results in increased expression of SYTL5 mRNA CTD PMID:19167446 Sytl5 Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of SYTL5 mRNA CTD PMID:27523638 Sytl5 Rat cyclosporin A decreases expression ISO SYTL5 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of SYTL5 mRNA CTD PMID:27989131 Sytl5 Rat dorsomorphin multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Sytl5 Rat Enterolactone multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SYTL5 mRNA CTD PMID:19167446 Sytl5 Rat ethanol increases expression ISO Sytl5 (Mus musculus) 6480464 Ethanol results in increased expression of SYTL5 mRNA CTD PMID:30319688 Sytl5 Rat glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of SYTL5 gene CTD PMID:35440735 Sytl5 Rat ivermectin decreases expression ISO SYTL5 (Homo sapiens) 6480464 Ivermectin results in decreased expression of SYTL5 protein CTD PMID:32959892 Sytl5 Rat Licochalcone B decreases expression ISO SYTL5 (Homo sapiens) 6480464 licochalcone B results in decreased expression of SYTL5 mRNA CTD PMID:33647349 Sytl5 Rat lipopolysaccharide multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SYTL5 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Sytl5 Rat methotrexate increases mutagenesis ISO Sytl5 (Mus musculus) 6480464 Methotrexate results in increased mutagenesis of SYTL5 gene CTD PMID:22806879 Sytl5 Rat methylmercury chloride decreases expression ISO SYTL5 (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of SYTL5 mRNA CTD PMID:23179753|PMID:28001369 Sytl5 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Sytl5 (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SYTL5 mRNA CTD PMID:36189433 Sytl5 Rat Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of SYTL5 mRNA CTD PMID:21515302 Sytl5 Rat O-methyleugenol decreases expression ISO SYTL5 (Homo sapiens) 6480464 methyleugenol results in decreased expression of SYTL5 mRNA CTD PMID:32234424 Sytl5 Rat okadaic acid decreases expression ISO SYTL5 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of SYTL5 mRNA CTD PMID:38832940 Sytl5 Rat ozone multiple interactions ISO Sytl5 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SYTL5 more ... CTD PMID:34911549 Sytl5 Rat paracetamol increases expression ISO Sytl5 (Mus musculus) 6480464 Acetaminophen results in increased expression of SYTL5 mRNA CTD PMID:29246445 Sytl5 Rat paracetamol multiple interactions ISO Sytl5 (Mus musculus) 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of SYTL5 mRNA] CTD PMID:29246445 Sytl5 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of SYTL5 mRNA CTD PMID:32680482 Sytl5 Rat PCB138 multiple interactions ISO Sytl5 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Sytl5 Rat perfluorooctanoic acid multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] more ... CTD PMID:33325755 Sytl5 Rat phenylmercury acetate increases expression ISO SYTL5 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of SYTL5 mRNA CTD PMID:26272509 Sytl5 Rat phenylmercury acetate multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Sytl5 Rat phytoestrogen multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] more ... CTD PMID:33325755 Sytl5 Rat progesterone multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of SYTL5 mRNA CTD PMID:20660070 Sytl5 Rat resveratrol multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of SYTL5 mRNA CTD PMID:19167446 Sytl5 Rat S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO SYTL5 (Homo sapiens) 6480464 S-(1,2-dichlorovinyl)cysteine results in increased expression of SYTL5 mRNA CTD PMID:35811015 Sytl5 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SYTL5 mRNA; [S-(1,2-dichlorovinyl)cysteine more ... CTD PMID:35811015 Sytl5 Rat SB 431542 multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Sytl5 Rat silver atom decreases expression ISO Sytl5 (Mus musculus) 6480464 Silver results in decreased expression of SYTL5 mRNA CTD PMID:27131904 Sytl5 Rat silver(0) decreases expression ISO Sytl5 (Mus musculus) 6480464 Silver results in decreased expression of SYTL5 mRNA CTD PMID:27131904 Sytl5 Rat sodium arsenite decreases expression ISO SYTL5 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of SYTL5 mRNA CTD PMID:34032870 Sytl5 Rat sodium arsenite decreases expression ISO Sytl5 (Mus musculus) 6480464 sodium arsenite results in decreased expression of SYTL5 mRNA CTD PMID:37682722 Sytl5 Rat sodium fluoride decreases expression ISO Sytl5 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of SYTL5 mRNA CTD PMID:27862939 Sytl5 Rat sunitinib decreases expression ISO SYTL5 (Homo sapiens) 6480464 Sunitinib results in decreased expression of SYTL5 mRNA CTD PMID:31533062 Sytl5 Rat tetrachloromethane increases expression ISO Sytl5 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of SYTL5 mRNA CTD PMID:29987408 Sytl5 Rat titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of SYTL5 mRNA CTD PMID:30012374 Sytl5 Rat trichostatin A decreases expression ISO SYTL5 (Homo sapiens) 6480464 trichostatin A results in decreased expression of SYTL5 mRNA CTD PMID:24935251 Sytl5 Rat triptonide increases expression ISO Sytl5 (Mus musculus) 6480464 triptonide results in increased expression of SYTL5 mRNA CTD PMID:33045310 Sytl5 Rat troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SYTL5 mRNA CTD PMID:21515302 Sytl5 Rat valproic acid decreases expression ISO SYTL5 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of SYTL5 mRNA CTD PMID:23179753 Sytl5 Rat valproic acid increases expression ISO SYTL5 (Homo sapiens) 6480464 Valproic Acid results in increased expression of SYTL5 mRNA CTD PMID:24383497|PMID:28001369 Sytl5 Rat valproic acid affects expression ISO SYTL5 (Homo sapiens) 6480464 Valproic Acid affects the expression of SYTL5 mRNA CTD PMID:25979313 Sytl5 Rat vorinostat multiple interactions ISO SYTL5 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Sytl5 Rat vorinostat increases expression ISO SYTL5 (Homo sapiens) 6480464 vorinostat results in increased expression of SYTL5 mRNA CTD PMID:26272509