Sorbs3 (sorbin and SH3 domain containing 3) - Rat Genome Database

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Gene: Sorbs3 (sorbin and SH3 domain containing 3) Rattus norvegicus
Analyze
Symbol: Sorbs3
Name: sorbin and SH3 domain containing 3
RGD ID: 628900
Description: Predicted to enable vinculin binding activity. Predicted to be involved in cell-substrate adhesion and positive regulation of stress fiber assembly. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of MAPK cascade. Predicted to be located in focal adhesion. Predicted to be active in cell-substrate junction; cytoplasm; and nucleus. Orthologous to human SORBS3 (sorbin and SH3 domain containing 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC94509; SH3 domain protein 4; Sh3d4; vinexin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,662,639 - 51,699,161 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1551,663,095 - 51,694,522 (-)EnsemblGRCr8
mRatBN7.21545,252,921 - 45,284,758 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,253,379 - 45,284,758 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1549,371,228 - 49,402,614 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,482,720 - 50,514,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,342,042 - 47,373,427 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01551,859,004 - 51,895,707 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,859,462 - 51,890,832 (-)Ensemblrn6Rnor6.0
Rnor_5.01555,585,158 - 55,618,036 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41550,580,018 - 50,611,107 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1544,932,832 - 44,964,037 (-)NCBICelera
RGSC_v3.11550,601,396 - 50,620,517 (-)NCBI
Cytogenetic Map15p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
aldrin  (ISO)
ammonium chloride  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroethene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
disodium selenite  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fenvalerate  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
FR900359  (ISO)
furan  (ISO)
gentamycin  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
okadaic acid  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anchoring junction  (IEA)
cytoplasm  (IEA,ISO)
focal adhesion  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin. Mitsushima M, etal., J Biol Chem 2004 Aug 13;279(33):34570-7. Epub 2004 Jun 7.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:9885244   PMID:12477932   PMID:14625289   PMID:15734736   PMID:15836771   PMID:16831423   PMID:18662323   PMID:21423176   PMID:23325552   PMID:25824575  


Genomics

Comparative Map Data
Sorbs3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,662,639 - 51,699,161 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1551,663,095 - 51,694,522 (-)EnsemblGRCr8
mRatBN7.21545,252,921 - 45,284,758 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,253,379 - 45,284,758 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1549,371,228 - 49,402,614 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,482,720 - 50,514,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,342,042 - 47,373,427 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01551,859,004 - 51,895,707 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1551,859,462 - 51,890,832 (-)Ensemblrn6Rnor6.0
Rnor_5.01555,585,158 - 55,618,036 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41550,580,018 - 50,611,107 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1544,932,832 - 44,964,037 (-)NCBICelera
RGSC_v3.11550,601,396 - 50,620,517 (-)NCBI
Cytogenetic Map15p11NCBI
SORBS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,544,973 - 22,575,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,544,986 - 22,575,788 (+)Ensemblhg38GRCh38
GRCh37822,409,440 - 22,433,301 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,465,196 - 22,488,953 (+)NCBIBuild 36Build 36hg18NCBI36
Celera821,370,859 - 21,394,614 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,951,413 - 20,975,170 (+)NCBIHuRef
CHM1_1822,611,605 - 22,635,365 (+)NCBICHM1_1
T2T-CHM13v2.0822,815,216 - 22,849,637 (+)NCBIT2T-CHM13v2.0
Sorbs3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,417,917 - 70,449,472 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,417,917 - 70,449,438 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381470,180,468 - 70,212,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,180,468 - 70,211,989 (-)Ensemblmm10GRCm38
MGSCv371470,580,275 - 70,607,444 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361468,915,548 - 68,942,717 (-)NCBIMGSCv36mm8
Celera1467,721,818 - 67,749,014 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.27NCBI
Sorbs3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,977,245 - 46,006,355 (+)Ensembl
ChiLan1.0NW_00495540345,973,381 - 46,003,807 (+)NCBIChiLan1.0ChiLan1.0
SORBS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2741,050,309 - 41,082,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,773,546 - 16,807,767 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,794,805 - 21,825,675 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,733,782 - 18,763,861 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,733,776 - 18,763,861 (+)EnsemblpanPan2panpan1.1
SORBS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12534,701,495 - 34,725,231 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2534,702,238 - 34,709,811 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2535,291,141 - 35,319,691 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02534,910,981 - 34,939,521 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2534,910,980 - 34,939,081 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12534,857,398 - 34,885,906 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02534,711,480 - 34,739,991 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02534,867,033 - 34,895,680 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sorbs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,254,249 - 12,287,361 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365556,292,205 - 6,316,306 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365556,292,213 - 6,316,264 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SORBS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,808,166 - 6,828,975 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1146,802,944 - 6,831,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2147,284,853 - 7,311,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SORBS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,627,947 - 20,655,700 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,630,437 - 20,656,154 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605221,571,447 - 21,596,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sorbs3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475818,058,306 - 18,084,378 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475818,058,972 - 18,083,509 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sorbs3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11254,141,889 - 54,168,878 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sorbs3
262 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:47
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000012056
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
2306968Anxrr23Anxiety related response QTL 234.83reflex trait (VT:0001961)amplitude of the acoustic startle response (CMO:0001520)154480677352597086Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
7411725Strs7Sensitivity to stroke QTL 73.8cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)154446544756583797Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
U58889  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,253,377 - 45,253,488 (+)MAPPERmRatBN7.2
Rnor_6.01551,859,461 - 51,859,571NCBIRnor6.0
Rnor_5.01555,585,615 - 55,585,725UniSTSRnor5.0
RGSC_v3.41550,580,018 - 50,580,128UniSTSRGSC3.4
Celera1544,932,832 - 44,932,942UniSTS
Cytogenetic Map15p11UniSTS
RH131880  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,252,922 - 45,253,072 (+)MAPPERmRatBN7.2
Rnor_6.01551,859,006 - 51,859,155NCBIRnor6.0
Rnor_5.01555,585,160 - 55,585,309UniSTSRnor5.0
RGSC_v3.41550,579,563 - 50,579,712UniSTSRGSC3.4
Celera1544,932,377 - 44,932,526UniSTS
Cytogenetic Map15p11UniSTS
RH143582  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,264,351 - 45,264,470 (+)MAPPERmRatBN7.2
Rnor_6.01551,870,435 - 51,870,553NCBIRnor6.0
Rnor_5.01555,596,191 - 55,596,309UniSTSRnor5.0
RGSC_v3.41550,591,183 - 50,591,301UniSTSRGSC3.4
Celera1544,943,654 - 44,943,772UniSTS
Cytogenetic Map15p11UniSTS
RH138866  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,284,093 - 45,284,223 (+)MAPPERmRatBN7.2
Rnor_6.01551,890,168 - 51,890,297NCBIRnor6.0
Rnor_5.01555,616,295 - 55,616,424UniSTSRnor5.0
RGSC_v3.41550,610,443 - 50,610,572UniSTSRGSC3.4
Celera1544,963,373 - 44,963,502UniSTS
Cytogenetic Map15p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 85 212 91 90 59 157 59 6 491 285 22 190 116 124 31 34 34

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005493698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF439378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000012056   ⟹   ENSRNOP00000012056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1551,663,095 - 51,694,522 (-)Ensembl
mRatBN7.2 Ensembl1545,253,379 - 45,284,758 (-)Ensembl
Rnor_6.0 Ensembl1551,859,462 - 51,890,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113720   ⟹   ENSRNOP00000095020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1545,253,379 - 45,275,866 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114102   ⟹   ENSRNOP00000076812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1551,663,095 - 51,694,472 (-)Ensembl
mRatBN7.2 Ensembl1545,253,379 - 45,284,758 (-)Ensembl
RefSeq Acc Id: NM_001005762   ⟹   NP_001005762
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,663,094 - 51,694,472 (-)NCBI
mRatBN7.21545,253,378 - 45,284,758 (-)NCBI
Rnor_6.01551,859,461 - 51,890,832 (-)NCBI
Rnor_5.01555,585,158 - 55,618,036 (-)NCBI
RGSC_v3.41550,580,018 - 50,611,107 (-)RGD
Celera1544,932,832 - 44,964,037 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252242   ⟹   XP_006252304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,662,639 - 51,692,436 (-)NCBI
mRatBN7.21545,252,921 - 45,281,138 (-)NCBI
Rnor_6.01551,859,004 - 51,887,219 (-)NCBI
Rnor_5.01555,585,158 - 55,618,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093073   ⟹   XP_038949001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,662,639 - 51,699,161 (-)NCBI
mRatBN7.21545,252,921 - 45,280,380 (-)NCBI
RefSeq Acc Id: XM_039093074   ⟹   XP_038949002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,662,639 - 51,683,594 (-)NCBI
mRatBN7.21545,252,921 - 45,278,728 (-)NCBI
RefSeq Acc Id: XM_063274057   ⟹   XP_063130127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,662,639 - 51,699,161 (-)NCBI
RefSeq Acc Id: XM_063274058   ⟹   XP_063130128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,662,639 - 51,699,161 (-)NCBI
RefSeq Acc Id: XM_063274060   ⟹   XP_063130130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,672,389 - 51,699,161 (-)NCBI
RefSeq Acc Id: XM_063274061   ⟹   XP_063130131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,673,766 - 51,699,161 (-)NCBI
RefSeq Acc Id: XR_005493698
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,672,679 - 51,699,161 (-)NCBI
mRatBN7.21545,262,962 - 45,280,380 (-)NCBI
RefSeq Acc Id: NP_001005762   ⟸   NM_001005762
- UniProtKB: Q5XIL4 (UniProtKB/TrEMBL),   A6HTJ5 (UniProtKB/TrEMBL),   A0A8I5Y5L8 (UniProtKB/TrEMBL),   F7EV37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252304   ⟸   XM_006252242
- Peptide Label: isoform X1
- UniProtKB: Q5XIL4 (UniProtKB/TrEMBL),   A6HTJ5 (UniProtKB/TrEMBL),   A0A8I5Y5L8 (UniProtKB/TrEMBL),   F7EV37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012056   ⟸   ENSRNOT00000012056
RefSeq Acc Id: XP_038949001   ⟸   XM_039093073
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y5L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949002   ⟸   XM_039093074
- Peptide Label: isoform X3
- UniProtKB: A6HTJ6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076812   ⟸   ENSRNOT00000114102
Ensembl Acc Id: ENSRNOP00000095020   ⟸   ENSRNOT00000113720
RefSeq Acc Id: XP_063130128   ⟸   XM_063274058
- Peptide Label: isoform X1
- UniProtKB: A6HTJ5 (UniProtKB/TrEMBL),   F7EV37 (UniProtKB/TrEMBL),   Q5XIL4 (UniProtKB/TrEMBL),   A0A8I5Y5L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130127   ⟸   XM_063274057
- Peptide Label: isoform X1
- UniProtKB: A6HTJ5 (UniProtKB/TrEMBL),   F7EV37 (UniProtKB/TrEMBL),   Q5XIL4 (UniProtKB/TrEMBL),   A0A8I5Y5L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130130   ⟸   XM_063274060
- Peptide Label: isoform X4
- UniProtKB: Q8CJ75 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130131   ⟸   XM_063274061
- Peptide Label: isoform X5
Protein Domains
SH3   SoHo

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIL4-F1-model_v2 AlphaFold Q5XIL4 1-733 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699806
Promoter ID:EPDNEW_R10329
Type:multiple initiation site
Name:Sorbs3_1
Description:sorbin and SH3 domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01551,890,909 - 51,890,969EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628900 AgrOrtholog
BioCyc Gene G2FUF-13234 BioCyc
Ensembl Genes ENSRNOG00000008829 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012056 ENTREZGENE
  ENSRNOT00000012056.6 UniProtKB/TrEMBL
  ENSRNOT00000114102 ENTREZGENE
  ENSRNOT00000114102.2 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135547 IMAGE-MGC_LOAD
InterPro Endophilin_SH3RF UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
  Vinexin_SH3_1 UniProtKB/TrEMBL
  Vinexin_SH3_2 UniProtKB/TrEMBL
  Vinexin_SH3_3 UniProtKB/TrEMBL
KEGG Report rno:282843 UniProtKB/TrEMBL
MGC_CLONE MGC:94509 IMAGE-MGC_LOAD
NCBI Gene 282843 ENTREZGENE
PANTHER PTHR14167:SF54 UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
PhenoGen Sorbs3 PhenoGen
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
  SOHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008829 RatGTEx
SMART SH3 UniProtKB/TrEMBL
  Sorb UniProtKB/TrEMBL
Superfamily-SCOP SH3 UniProtKB/TrEMBL
UniProt A0A8I5Y5L8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NN96_RAT UniProtKB/TrEMBL
  A6HTJ5 ENTREZGENE, UniProtKB/TrEMBL
  A6HTJ6 ENTREZGENE, UniProtKB/TrEMBL
  F7EV37 ENTREZGENE, UniProtKB/TrEMBL
  Q5XIL4 ENTREZGENE
  Q8CJ75 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5XIL4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Sorbs3  sorbin and SH3 domain containing 3  Sh3d4  SH3 domain protein 4  Symbol and Name updated 1299863 APPROVED
2005-01-20 Sh3d4  SH3 domain protein 4      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Sh3d4  SH3 domain protein 4      Symbol and Name status set to provisional 70820 PROVISIONAL