Fbln2 (fibulin 2) - Rat Genome Database

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Gene: Fbln2 (fibulin 2) Rattus norvegicus
Analyze
Symbol: Fbln2
Name: fibulin 2
RGD ID: 628685
Description: Predicted to enable extracellular matrix binding activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in positive regulation of cell-substrate adhesion. Predicted to be active in extracellular matrix and extracellular region. Orthologous to human FBLN2 (fibulin 2); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fibulin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84125,261,464 - 125,321,030 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4125,261,607 - 125,321,029 (+)EnsemblGRCr8
mRatBN7.24123,704,289 - 123,763,857 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4123,704,373 - 123,763,948 (+)EnsemblmRatBN7.2
Rnor_6.04122,835,237 - 122,895,127 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4122,835,436 - 122,895,121 (+)Ensemblrn6Rnor6.0
Rnor_5.04187,650,676 - 187,710,505 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44125,380,549 - 125,441,079 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4112,624,458 - 112,683,251 (+)NCBICelera
RGSC_v3.14125,667,843 - 125,678,673 (+)NCBI
Cytogenetic Map4q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
Azoxymethane  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
caffeine  (EXP)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
corticosterone  (EXP)
curcumin  (ISO)
dextran sulfate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
iron dichloride  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
lidocaine  (EXP)
manganese(II) chloride  (EXP)
methapyrilene  (ISO)
methoxyacetic acid  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (ISO)
nitrofen  (EXP)
paracetamol  (EXP)
paricalcitol  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenylmercury acetate  (ISO)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Study of drug use by students in a village in Brussels Decrucq J and Sand EA, Arch Belg Med Soc 1977 May;35(5):297-311.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18757743   PMID:19609566   PMID:23376485   PMID:23612897   PMID:23658023   PMID:24006456   PMID:24769233   PMID:26051800   PMID:27068509   PMID:27559042  


Genomics

Comparative Map Data
Fbln2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84125,261,464 - 125,321,030 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4125,261,607 - 125,321,029 (+)EnsemblGRCr8
mRatBN7.24123,704,289 - 123,763,857 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4123,704,373 - 123,763,948 (+)EnsemblmRatBN7.2
Rnor_6.04122,835,237 - 122,895,127 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4122,835,436 - 122,895,121 (+)Ensemblrn6Rnor6.0
Rnor_5.04187,650,676 - 187,710,505 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44125,380,549 - 125,441,079 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4112,624,458 - 112,683,251 (+)NCBICelera
RGSC_v3.14125,667,843 - 125,678,673 (+)NCBI
Cytogenetic Map4q34NCBI
FBLN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38313,549,125 - 13,638,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl313,549,073 - 13,638,422 (+)Ensemblhg38GRCh38
GRCh37313,590,625 - 13,679,904 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36313,565,625 - 13,654,923 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34313,565,624 - 13,654,922NCBI
Celera313,528,888 - 13,618,185 (+)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef313,524,043 - 13,613,389 (+)NCBIHuRef
CHM1_1313,540,651 - 13,629,945 (+)NCBICHM1_1
T2T-CHM13v2.0313,549,579 - 13,638,882 (+)NCBIT2T-CHM13v2.0
Fbln2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,189,442 - 91,249,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl691,189,437 - 91,249,522 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38691,212,460 - 91,272,540 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,212,455 - 91,272,540 (+)Ensemblmm10GRCm38
MGSCv37691,162,758 - 91,222,534 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36691,178,368 - 91,238,044 (+)NCBIMGSCv36mm8
Celera693,105,530 - 93,166,173 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.42NCBI
Fbln2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542912,788,468 - 12,880,543 (-)Ensembl
ChiLan1.0NW_00495542912,791,926 - 12,880,544 (-)NCBIChiLan1.0ChiLan1.0
FBLN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2213,528,891 - 13,617,467 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1313,533,695 - 13,622,231 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0313,469,679 - 13,558,241 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1313,812,462 - 13,900,332 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl313,812,462 - 13,900,332 (+)EnsemblpanPan2panpan1.1
FBLN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1203,874,896 - 3,935,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl203,874,896 - 3,934,717 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha203,878,680 - 3,976,554 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0203,860,863 - 3,959,730 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl203,872,419 - 3,959,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1203,579,996 - 3,678,796 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0203,902,733 - 4,001,506 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0203,867,708 - 3,965,607 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbln2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494219,542,313 - 19,578,312 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936898113,064 - 133,177 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936898112,687 - 148,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBLN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1370,757,265 - 70,830,388 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11370,757,255 - 70,830,430 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21378,321,495 - 78,338,494 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBLN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12249,540,316 - 49,630,380 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2249,564,822 - 49,630,409 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041116,866,783 - 116,956,971 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbln2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479612,570,139 - 12,636,987 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479612,570,112 - 12,637,019 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbln2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1655,668,212 - 55,726,710 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbln2
1047 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:322
Count of miRNA genes:123
Interacting mature miRNAs:135
Transcripts:ENSRNOT00000009696, ENSRNOT00000037256
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat

Markers in Region
D4Rat183  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84125,275,097 - 125,275,227 (+)Marker Load Pipeline
mRatBN7.24123,717,924 - 123,718,054 (+)MAPPERmRatBN7.2
Rnor_6.04122,848,831 - 122,848,960NCBIRnor6.0
Rnor_5.04187,696,821 - 187,696,950UniSTSRnor5.0
RGSC_v3.44125,393,988 - 125,394,118RGDRGSC3.4
RGSC_v3.44125,393,989 - 125,394,118UniSTSRGSC3.4
Celera4112,638,042 - 112,638,171UniSTS
RGSC_v3.14125,638,459 - 125,638,829RGD
SHRSP x BN Map454.33RGD
SHRSP x BN Map454.33UniSTS
Cytogenetic Map4q34UniSTS
RH128760  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24123,763,541 - 123,763,721 (+)MAPPERmRatBN7.2
Rnor_6.04122,894,812 - 122,894,991NCBIRnor6.0
Rnor_5.04187,650,811 - 187,650,991NCBIRnor5.0
RGSC_v3.44125,440,764 - 125,440,943UniSTSRGSC3.4
Celera4112,682,936 - 112,683,115UniSTS
RH 3.4 Map4736.01UniSTS
Cytogenetic Map4q34UniSTS
UniSTS:235496  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24123,724,546 - 123,724,683 (+)MAPPERmRatBN7.2
Rnor_6.04122,855,453 - 122,855,589NCBIRnor6.0
Rnor_5.04187,690,192 - 187,690,328UniSTSRnor5.0
RGSC_v3.44125,400,611 - 125,400,747UniSTSRGSC3.4
Celera4112,644,664 - 112,644,800UniSTS
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 67 156 91 90 59 46 59 6 306 146 11 135 79 92 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000009696   ⟹   ENSRNOP00000009696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4125,261,607 - 125,321,029 (+)Ensembl
mRatBN7.2 Ensembl4123,704,373 - 123,763,948 (+)Ensembl
Rnor_6.0 Ensembl4122,835,436 - 122,895,121 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103947   ⟹   ENSRNOP00000078229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4125,261,607 - 125,321,029 (+)Ensembl
mRatBN7.2 Ensembl4123,704,373 - 123,763,948 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115833   ⟹   ENSRNOP00000086234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4125,261,650 - 125,321,029 (+)Ensembl
mRatBN7.2 Ensembl4123,704,373 - 123,763,948 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127297   ⟹   ENSRNOP00000099602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4125,261,650 - 125,321,029 (+)Ensembl
RefSeq Acc Id: NM_001100490   ⟹   NP_001093960
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84125,261,659 - 125,321,030 (+)NCBI
RefSeq Acc Id: XM_006236924   ⟹   XP_006236986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84125,261,464 - 125,321,030 (+)NCBI
mRatBN7.24123,704,289 - 123,763,422 (+)NCBI
Rnor_6.04122,835,237 - 122,894,692 (+)NCBI
Rnor_5.04187,650,676 - 187,710,505 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006236986   ⟸   XM_006236924
- Peptide Label: isoform X1
- UniProtKB: A6IB95 (UniProtKB/TrEMBL),   A0A8I6A720 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009696   ⟸   ENSRNOT00000009696
Ensembl Acc Id: ENSRNOP00000078229   ⟸   ENSRNOT00000103947
Ensembl Acc Id: ENSRNOP00000086234   ⟸   ENSRNOT00000115833
RefSeq Acc Id: NP_001093960   ⟸   NM_001100490
- Peptide Label: precursor
- UniProtKB: A6IB94 (UniProtKB/TrEMBL),   G3V6X1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000099602   ⟸   ENSRNOT00000127297
Protein Domains
Anaphylatoxin-like   EGF-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6X1-F1-model_v2 AlphaFold G3V6X1 1-1221 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693254
Promoter ID:EPDNEW_R3773
Type:initiation region
Name:Fbln2_1
Description:fibulin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04122,835,432 - 122,835,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628685 AgrOrtholog
BioCyc Gene G2FUF-43725 BioCyc
Ensembl Genes ENSRNOG00000007338 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009696 ENTREZGENE
  ENSRNOT00000009696.9 UniProtKB/TrEMBL
  ENSRNOT00000103947.2 UniProtKB/TrEMBL
  ENSRNOT00000115833 ENTREZGENE
  ENSRNOT00000115833.2 UniProtKB/TrEMBL
  ENSRNOT00000127297.1 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro Anaphylatoxin/fibulin UniProtKB/TrEMBL
  cEGF UniProtKB/TrEMBL
  ECM_structural_protein UniProtKB/TrEMBL
  EGF-like_Ca-bd UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  FIBL-2_dom UniProtKB/TrEMBL
  Fibulin_C UniProtKB/TrEMBL
  Growth_fac_rcpt_N_dom UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
NCBI Gene 282583 ENTREZGENE
PANTHER EGF-LIKE AND EMI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  HEMICENTIN 2 UniProtKB/TrEMBL
Pfam ANATO UniProtKB/TrEMBL
  cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FIBL-2 UniProtKB/TrEMBL
  Fibulin_C UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/TrEMBL
PhenoGen Fbln2 PhenoGen
PROSITE ANAPHYLATOXIN_1 UniProtKB/TrEMBL
  ANAPHYLATOXIN_2 UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007338 RatGTEx
SMART ANATO UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8I5ZJQ3_RAT UniProtKB/TrEMBL
  A0A8I6A720 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L5Z2_RAT UniProtKB/TrEMBL
  A6IB94 ENTREZGENE, UniProtKB/TrEMBL
  A6IB95 ENTREZGENE, UniProtKB/TrEMBL
  G3V6X1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Fbln2  fibulin 2      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Fbln2  fibulin 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process developmental changes of expression correlated with cellular development of the testis 708328