Gene: Uxs1 (UDP-glucuronate decarboxylase 1) Rattus norvegicus
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Symbol:
Uxs1
Name:
UDP-glucuronate decarboxylase 1
RGD ID:
628680
Description:
Enables UDP-glucuronate decarboxylase activity. Predicted to be involved in UDP-D-xylose biosynthetic process. Located in Golgi membrane. Orthologous to human UXS1 (UDP-glucuronate decarboxylase 1); PARTICIPATES IN galactokinase deficiency pathway; GALE deficiency pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; ammonium chloride.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
MGC93157; UDP-glucuronic acid decarboxylase 1; UGD; UXS-1
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 9 740,929 - 818,310 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 9 740,724 - 818,319 (+) Ensembl GRCr8 mRatBN7.2 9 653,740 - 731,121 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 9 653,659 - 756,334 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 9 1,101,032 - 1,178,186 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 9 6,448,086 - 6,525,417 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 9 5,338,604 - 5,415,805 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 9 11,165,006 - 11,240,329 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 9 11,164,715 - 11,339,790 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 9 10,150,134 - 10,226,955 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 Celera 9 7,775,435 - 7,852,399 (-) NCBI Celera Cytogenetic Map 9 q11 NCBI
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Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Uxs1 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Uxs1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uxs1 Rat 1,2-dichloroethane decreases expression ISO Uxs1 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of UXS1 mRNA CTD PMID:28960355 Uxs1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Uxs1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uxs1 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Uxs1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uxs1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Uxs1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of UXS1 mRNA CTD PMID:21570461 Uxs1 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Uxs1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uxs1 Rat 4,4'-diaminodiphenylmethane increases expression ISO Uxs1 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of UXS1 mRNA CTD PMID:18648102 Uxs1 Rat 4-hydroxyphenyl retinamide decreases expression ISO Uxs1 (Mus musculus) 6480464 Fenretinide results in decreased expression of UXS1 mRNA CTD PMID:28973697 Uxs1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of UXS1 mRNA CTD PMID:30047161 Uxs1 Rat aflatoxin B1 decreases methylation ISO UXS1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of UXS1 intron CTD PMID:30157460 Uxs1 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of UXS1 mRNA CTD PMID:38685447 Uxs1 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of UXS1 mRNA CTD PMID:30047161 Uxs1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of UXS1 mRNA CTD PMID:16483693 Uxs1 Rat atrazine increases expression ISO UXS1 (Homo sapiens) 6480464 Atrazine results in increased expression of UXS1 mRNA CTD PMID:22378314 Uxs1 Rat benzo[a]pyrene increases methylation ISO Uxs1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased methylation of UXS1 intron CTD PMID:27901495 Uxs1 Rat benzo[a]pyrene increases expression ISO UXS1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of UXS1 mRNA CTD PMID:32234424 Uxs1 Rat bilirubin IXalpha decreases expression ISO UXS1 (Homo sapiens) 6480464 Bilirubin results in decreased expression of UXS1 mRNA CTD PMID:20196124 Uxs1 Rat bisphenol A increases expression ISO Uxs1 (Mus musculus) 6480464 bisphenol A results in increased expression of UXS1 mRNA CTD PMID:26063408 Uxs1 Rat bisphenol A multiple interactions ISO UXS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of UXS1 gene CTD PMID:31601247 Uxs1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of UXS1 mRNA CTD PMID:25181051 Uxs1 Rat bisphenol F increases expression ISO Uxs1 (Mus musculus) 6480464 bisphenol F results in increased expression of UXS1 mRNA CTD PMID:38685157 Uxs1 Rat carbon nanotube increases expression ISO Uxs1 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of UXS1 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25554681 Uxs1 Rat cocaine affects expression EXP 6480464 Cocaine affects the expression of UXS1 mRNA CTD PMID:20187946 Uxs1 Rat cyclosporin A decreases expression ISO UXS1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of UXS1 mRNA CTD PMID:25562108 Uxs1 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of UXS1 mRNA CTD PMID:21266533 Uxs1 Rat doxorubicin decreases expression ISO UXS1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of UXS1 mRNA CTD PMID:29803840 Uxs1 Rat dTDP multiple interactions ISO UXS1 (Homo sapiens) 6480464 [thymidine 5'-diphosphate co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat ethanol affects splicing ISO Uxs1 (Mus musculus) 6480464 Ethanol affects the splicing of UXS1 mRNA CTD PMID:30319688 Uxs1 Rat finasteride increases expression EXP 6480464 Finasteride results in increased expression of UXS1 mRNA CTD PMID:24136188 Uxs1 Rat fipronil increases expression EXP 6480464 fipronil results in increased expression of UXS1 mRNA CTD PMID:31881178 Uxs1 Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of UXS1 mRNA CTD PMID:18035473 Uxs1 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of UXS1 mRNA CTD PMID:24136188 Uxs1 Rat fulvestrant multiple interactions ISO UXS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of UXS1 gene CTD PMID:31601247 Uxs1 Rat GSK-J4 decreases expression ISO UXS1 (Homo sapiens) 6480464 GSK-J4 results in decreased expression of UXS1 mRNA CTD PMID:29301935 Uxs1 Rat ivermectin decreases expression ISO UXS1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of UXS1 protein CTD PMID:32959892 Uxs1 Rat lead diacetate decreases expression ISO Uxs1 (Mus musculus) 6480464 lead acetate results in decreased expression of UXS1 mRNA CTD PMID:20542052 Uxs1 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of UXS1 mRNA CTD PMID:38685447 Uxs1 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of UXS1 mRNA CTD PMID:30047161 Uxs1 Rat NAD zwitterion multiple interactions ISO UXS1 (Homo sapiens) 6480464 [thymidine 5'-diphosphate co-treated with NAD] binds to UXS1 protein; [Uridine Diphosphate Galactose co-treated with NAD] more ... CTD PMID:25526675 Uxs1 Rat NAD(+) multiple interactions ISO UXS1 (Homo sapiens) 6480464 [thymidine 5'-diphosphate co-treated with NAD] binds to UXS1 protein; [Uridine Diphosphate Galactose co-treated with NAD] more ... CTD PMID:25526675 Uxs1 Rat okadaic acid increases expression ISO UXS1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of UXS1 mRNA CTD PMID:38832940 Uxs1 Rat ozone multiple interactions ISO Uxs1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... CTD PMID:34911549 Uxs1 Rat paracetamol decreases expression ISO UXS1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of UXS1 mRNA CTD PMID:26690555 Uxs1 Rat paracetamol increases expression ISO UXS1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of UXS1 mRNA CTD PMID:29067470 Uxs1 Rat paraquat decreases expression ISO UXS1 (Homo sapiens) 6480464 Paraquat results in decreased expression of UXS1 protein CTD PMID:34064677 Uxs1 Rat PCB138 multiple interactions ISO Uxs1 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Uxs1 Rat pentachlorophenol increases expression ISO Uxs1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of UXS1 mRNA CTD PMID:23892564 Uxs1 Rat pirinixic acid increases expression ISO Uxs1 (Mus musculus) 6480464 pirinixic acid results in increased expression of UXS1 mRNA CTD PMID:17426115 Uxs1 Rat pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of UXS1 mRNA CTD PMID:30047161 Uxs1 Rat sodium arsenite decreases expression ISO UXS1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of UXS1 mRNA CTD PMID:20371982|PMID:38568856 Uxs1 Rat sulfadimethoxine increases expression EXP 6480464 Sulfadimethoxine results in increased expression of UXS1 mRNA CTD PMID:30047161 Uxs1 Rat tetrachloromethane increases expression ISO Uxs1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of UXS1 mRNA CTD PMID:31919559 Uxs1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of UXS1 mRNA CTD PMID:34492290 Uxs1 Rat tibolone decreases expression ISO UXS1 (Homo sapiens) 6480464 tibolone results in decreased expression of UXS1 mRNA CTD PMID:22217510 Uxs1 Rat titanium dioxide decreases expression ISO Uxs1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of UXS1 mRNA CTD PMID:29264374 Uxs1 Rat titanium dioxide decreases methylation ISO Uxs1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of UXS1 gene; titanium dioxide results in decreased methylation more ... CTD PMID:35295148 Uxs1 Rat triphenyl phosphate affects expression ISO UXS1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of UXS1 mRNA CTD PMID:37042841 Uxs1 Rat triptonide increases expression ISO Uxs1 (Mus musculus) 6480464 triptonide results in increased expression of UXS1 mRNA CTD PMID:33045310 Uxs1 Rat UDP-alpha-D-galactose multiple interactions ISO UXS1 (Homo sapiens) 6480464 [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat UDP-alpha-D-glucose multiple interactions ISO UXS1 (Homo sapiens) 6480464 [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat UDP-alpha-D-glucuronic acid multiple interactions ISO UXS1 (Homo sapiens) 6480464 [Uridine Diphosphate Glucuronic Acid co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat UDP-D-galactose multiple interactions ISO UXS1 (Homo sapiens) 6480464 [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat UDP-D-glucose multiple interactions ISO UXS1 (Homo sapiens) 6480464 [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 Uxs1 Rat valproic acid increases expression ISO UXS1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of UXS1 mRNA CTD PMID:23179753|PMID:29154799 Uxs1 Rat valproic acid affects expression ISO UXS1 (Homo sapiens) 6480464 Valproic Acid affects the expression of UXS1 mRNA CTD PMID:25979313 Uxs1 Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of UXS1 mRNA CTD PMID:23869203