Hspbp1 (HSPA (Hsp70) binding protein 1) - Rat Genome Database

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Gene: Hspbp1 (HSPA (Hsp70) binding protein 1) Rattus norvegicus
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Symbol: Hspbp1
Name: HSPA (Hsp70) binding protein 1
RGD ID: 628677
Description: Predicted to enable adenyl-nucleotide exchange factor activity; molecular sequestering activity; and ubiquitin protein ligase binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and positive regulation of protein ubiquitination. Predicted to be active in endoplasmic reticulum and extracellular space. Orthologous to human HSPBP1 (HSPA (Hsp70) binding protein 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heat shock protein-binding protein 1; hsp70-binding protein 1; hsp70-interacting protein; hsp70-interacting protein 1; HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HSPA binding protein, cytoplasmic cochaperone 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,194,067 - 78,217,836 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,189,305 - 78,217,835 (+)EnsemblGRCr8
mRatBN7.2169,165,394 - 69,189,062 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,165,572 - 69,244,593 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,510,676 - 74,534,082 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,074,977 - 83,098,381 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,227,624 - 76,251,222 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,732,418 - 72,756,087 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,732,668 - 72,756,082 (+)Ensemblrn6Rnor6.0
Rnor_5.0175,779,792 - 75,803,294 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4167,882,356 - 67,905,766 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera167,935,639 - 67,958,911 (-)NCBICelera
RGSC_v3.1167,960,466 - 67,983,877 (+)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Isolation and characterization of isoforms of HspBP1, inhibitors of Hsp70. Raynes DA and Guerriero V, Biochim Biophys Acta 2000 Jan 31;1490(1-2):203-7.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:16207813   PMID:16831871  


Genomics

Comparative Map Data
Hspbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,194,067 - 78,217,836 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,189,305 - 78,217,835 (+)EnsemblGRCr8
mRatBN7.2169,165,394 - 69,189,062 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,165,572 - 69,244,593 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,510,676 - 74,534,082 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,074,977 - 83,098,381 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,227,624 - 76,251,222 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,732,418 - 72,756,087 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,732,668 - 72,756,082 (+)Ensemblrn6Rnor6.0
Rnor_5.0175,779,792 - 75,803,294 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4167,882,356 - 67,905,766 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera167,935,639 - 67,958,911 (-)NCBICelera
RGSC_v3.1167,960,466 - 67,983,877 (+)NCBI
Cytogenetic Map1q12NCBI
HSPBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,262,223 - 55,280,383 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,262,219 - 55,280,930 (-)Ensemblhg38GRCh38
GRCh371955,773,591 - 55,791,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,465,519 - 60,483,285 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341960,465,410 - 60,483,540NCBI
Celera1952,815,211 - 52,832,757 (-)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,096,706 - 52,113,919 (-)NCBIHuRef
CHM1_11955,767,108 - 55,785,698 (-)NCBICHM1_1
T2T-CHM13v2.01958,356,168 - 58,375,917 (-)NCBIT2T-CHM13v2.0
Hspbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,663,514 - 4,688,218 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,663,520 - 4,688,067 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3874,660,515 - 4,685,188 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,660,521 - 4,685,068 (-)Ensemblmm10GRCm38
MGSCv3774,612,123 - 4,636,565 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3674,263,608 - 4,288,050 (-)NCBIMGSCv36mm8
Celera74,390,294 - 4,414,443 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.69NCBI
Hspbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567947,798 - 960,678 (+)Ensembl
ChiLan1.0NW_004955567948,040 - 960,621 (+)NCBIChiLan1.0ChiLan1.0
HSPBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,398,286 - 61,419,793 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,127,399 - 63,148,908 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,303,121 - 52,322,771 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11960,994,821 - 61,013,982 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1960,995,202 - 61,013,756 (-)EnsemblpanPan2panpan1.1
HSPBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,389,438 - 102,402,578 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,389,608 - 102,402,380 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1102,445,923 - 102,459,044 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01103,042,429 - 103,055,553 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,035,815 - 103,055,553 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,679,417 - 102,692,537 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,391,203 - 102,404,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,154,979 - 103,168,101 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hspbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,017,339 - 2,032,891 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886526,287 - 542,606 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936886526,334 - 541,931 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,452,935 - 59,464,533 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1659,452,934 - 59,464,533 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,381,517 - 54,392,897 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSPBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,861,634 - 47,884,293 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,861,593 - 47,884,218 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045461,611 - 515,736 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,998,005 - 2,009,683 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248321,997,748 - 2,009,683 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hspbp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12177,236,973 - 177,259,975 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hspbp1
375 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:53
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000024251
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024251   ⟹   ENSRNOP00000024251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,189,305 - 78,217,834 (+)Ensembl
mRatBN7.2 Ensembl169,165,572 - 69,244,593 (+)Ensembl
Rnor_6.0 Ensembl172,732,668 - 72,756,082 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000142878   ⟹   ENSRNOP00000099752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,190,298 - 78,217,835 (+)Ensembl
RefSeq Acc Id: NM_139261   ⟹   NP_640354
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,194,418 - 78,217,831 (+)NCBI
mRatBN7.2169,165,642 - 69,189,057 (+)NCBI
Rnor_6.0172,732,668 - 72,756,082 (+)NCBI
Rnor_5.0175,779,792 - 75,803,294 (-)NCBI
RGSC_v3.4167,882,356 - 67,905,766 (+)RGD
Celera167,935,639 - 67,958,911 (-)RGD
Sequence:
RefSeq Acc Id: XM_006228248   ⟹   XP_006228310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,194,070 - 78,217,836 (+)NCBI
mRatBN7.2169,165,412 - 69,189,062 (+)NCBI
Rnor_6.0172,732,438 - 72,756,087 (+)NCBI
Rnor_5.0175,779,792 - 75,803,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006228250   ⟹   XP_006228312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,194,067 - 78,217,836 (+)NCBI
mRatBN7.2169,165,511 - 69,189,062 (+)NCBI
Rnor_6.0172,732,504 - 72,756,087 (+)NCBI
Rnor_5.0175,779,792 - 75,803,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063280943   ⟹   XP_063137013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,194,068 - 78,217,836 (+)NCBI
RefSeq Acc Id: NP_640354   ⟸   NM_139261
- UniProtKB: Q6IMX7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006228310   ⟸   XM_006228248
- Peptide Label: isoform X1
- UniProtKB: Q9JLF4 (UniProtKB/Swiss-Prot),   Q6IMX7 (UniProtKB/Swiss-Prot),   A6KNM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228312   ⟸   XM_006228250
- Peptide Label: isoform X1
- UniProtKB: Q9JLF4 (UniProtKB/Swiss-Prot),   Q6IMX7 (UniProtKB/Swiss-Prot),   A6KNM8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024251   ⟸   ENSRNOT00000024251
RefSeq Acc Id: XP_063137013   ⟸   XM_063280943
- Peptide Label: isoform X1
- UniProtKB: Q9JLF4 (UniProtKB/Swiss-Prot),   Q6IMX7 (UniProtKB/Swiss-Prot),   A6KNM8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000099752   ⟸   ENSRNOT00000142878
Protein Domains
Nucleotide exchange factor Fes1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IMX7-F1-model_v2 AlphaFold Q6IMX7 1-357 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689701
Promoter ID:EPDNEW_R225
Type:multiple initiation site
Name:Hspbp1_1
Description:HSPA binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0172,732,609 - 72,732,669EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628677 AgrOrtholog
BioCyc Gene G2FUF-60848 BioCyc
Ensembl Genes ENSRNOG00000017795 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024251 ENTREZGENE
  ENSRNOT00000024251.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7103744 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  Hsp70_NEF-Inhibitors UniProtKB/Swiss-Prot
  Nucleotide_exch_fac_Fes1 UniProtKB/Swiss-Prot
KEGG Report rno:246146 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91470 IMAGE-MGC_LOAD
NCBI Gene 246146 ENTREZGENE
PANTHER HSP70-BINDING PROTEIN 1 UniProtKB/Swiss-Prot
  PROTEIN FOLDING REGULATOR UniProtKB/Swiss-Prot
Pfam Fes1 UniProtKB/Swiss-Prot
PhenoGen Hspbp1 PhenoGen
RatGTEx ENSRNOG00000017795 RatGTEx
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
UniProt A0ABK0KY14_RAT UniProtKB/TrEMBL
  A6KNM7_RAT UniProtKB/TrEMBL
  A6KNM8 ENTREZGENE, UniProtKB/TrEMBL
  HPBP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JLF4 ENTREZGENE
UniProt Secondary Q9JLF4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 Hspbp1  HSPA (Hsp70) binding protein 1  Hspbp1  HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-11 Hspbp1  HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1  Hspbp1  HSPA binding protein, cytoplasmic cochaperone 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-27 Hspbp1  HSPA binding protein, cytoplasmic cochaperone 1  Hspbp1  HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-26 Hspbp1  HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1  Hspbp1  hsp70-interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Hspbp1  hsp70-interacting protein      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Hspbp1  hsp70-interacting protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript differs from the human gene in the number of consecutive glycines near the amino-terminus 633081