Fstl3 (follistatin like 3) - Rat Genome Database

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Gene: Fstl3 (follistatin like 3) Rattus norvegicus
Analyze
Symbol: Fstl3
Name: follistatin like 3
RGD ID: 621811
Description: Predicted to enable activin binding activity and fibronectin binding activity. Involved in several processes, including adrenal gland development; male gonad development; and spermatogenesis. Located in extracellular space; neuron projection terminus; and secretory granule. Orthologous to human FSTL3 (follistatin like 3); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Flrg; follistatin-like 3; follistatin-like 3 (secreted glycoprotein); follistatin-like protein 3; follistatin-related gene protein; follistatin-related protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Fstl3em1Soar
Genetic Models: SD-Fstl3em1Soar
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,574,195 - 10,579,844 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,574,186 - 10,590,509 (-)EnsemblGRCr8
mRatBN7.279,923,574 - 9,929,223 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,923,576 - 9,939,639 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,805,686 - 12,810,209 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,683,767 - 14,688,290 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,543,082 - 12,547,606 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd713,322,213 - 13,327,856 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive713,485,663 - 13,491,306 (-)NCBILyon_Normotensive
Lyon_Hypertensive713,560,510 - 13,566,153 (-)NCBILyon_Hypertensive
F344_StmMcwi711,926,314 - 11,931,957 (-)NCBIF344_StmMcwi
Rnor_6.0712,806,031 - 12,810,556 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,804,919 - 12,810,570 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,976,235 - 12,980,760 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,438,360 - 11,442,885 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera78,098,196 - 8,102,721 (-)NCBICelera
RGSC_v3.1711,437,263 - 11,442,906 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butan-1-ol  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
diethyl maleate  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
ethanol  (ISO)
gentamycin  (EXP)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methimazole  (EXP)
mifepristone  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
phenylephrine  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
activin binding  (IBA,IEA,ISO)
fibronectin binding  (IEA,ISO)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Purification, cDNA cloning, and secretory properties of FLRG protein from PC12 cells and the distribution of FLRG mRNA and protein in rat tissues. Ohsawa Y, etal., Arch Histol Cytol 2003 Oct;66(4):367-81.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11010968   PMID:11739004   PMID:11948405   PMID:12493714   PMID:12697670   PMID:15451575   PMID:15574124   PMID:16150905   PMID:16336961   PMID:16935389   PMID:17868029   PMID:17878677  
PMID:18781389   PMID:20103742   PMID:21245136   PMID:22915069   PMID:24006456   PMID:25937185   PMID:34723652  


Genomics

Comparative Map Data
Fstl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,574,195 - 10,579,844 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,574,186 - 10,590,509 (-)EnsemblGRCr8
mRatBN7.279,923,574 - 9,929,223 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,923,576 - 9,939,639 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx712,805,686 - 12,810,209 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,683,767 - 14,688,290 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,543,082 - 12,547,606 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd713,322,213 - 13,327,856 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive713,485,663 - 13,491,306 (-)NCBILyon_Normotensive
Lyon_Hypertensive713,560,510 - 13,566,153 (-)NCBILyon_Hypertensive
F344_StmMcwi711,926,314 - 11,931,957 (-)NCBIF344_StmMcwi
Rnor_6.0712,806,031 - 12,810,556 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,804,919 - 12,810,570 (-)Ensemblrn6Rnor6.0
Rnor_5.0712,976,235 - 12,980,760 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,438,360 - 11,442,885 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera78,098,196 - 8,102,721 (-)NCBICelera
RGSC_v3.1711,437,263 - 11,442,906 (-)NCBI
Cytogenetic Map7q11NCBI
FSTL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819676,392 - 683,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19676,392 - 683,392 (+)Ensemblhg38GRCh38
GRCh3719676,392 - 683,385 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619627,389 - 634,392 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3419627,416 - 634,389NCBI
Celera19134,214 - 141,222 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19446,191 - 453,199 (+)NCBIHuRef
CHM1_119676,089 - 683,092 (+)NCBICHM1_1
T2T-CHM13v2.019630,475 - 637,473 (+)NCBIT2T-CHM13v2.0
Fstl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,613,108 - 79,618,464 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,613,106 - 79,618,464 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381079,777,274 - 79,782,630 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,777,272 - 79,782,630 (+)Ensemblmm10GRCm38
MGSCv371079,240,019 - 79,245,375 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361079,180,424 - 79,185,451 (+)NCBIMGSCv36mm8
Celera1080,791,969 - 80,797,325 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Fstl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,078,427 - 7,082,717 (-)Ensembl
ChiLan1.0NW_0049554957,077,424 - 7,082,768 (-)NCBIChiLan1.0ChiLan1.0
FSTL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,001,470 - 5,008,587 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,239,588 - 4,246,692 (+)NCBINHGRI_mPanPan1
FSTL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,878,623 - 57,884,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,879,722 - 57,884,172 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2057,680,806 - 57,686,436 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02058,621,365 - 58,627,006 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,621,362 - 58,626,955 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,675,541 - 57,681,139 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,155,035 - 58,160,630 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,358,373 - 58,363,941 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fstl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,578,861 - 217,584,426 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588250,249 - 256,902 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936588250,359 - 255,922 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSTL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,656,663 - 77,662,613 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1277,656,655 - 77,662,608 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FSTL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16425,050 - 435,931 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6425,106 - 436,431 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660818,513,455 - 8,530,949 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fstl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,843,906 - 7,848,134 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248287,842,903 - 7,848,181 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fstl3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11155,090,495 - 155,096,083 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fstl3
45 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:366
Count of miRNA genes:205
Interacting mature miRNAs:227
Transcripts:ENSRNOT00000012578
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
BE099290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,923,878 - 9,924,047 (+)MAPPERmRatBN7.2
Rnor_6.0712,805,240 - 12,805,408NCBIRnor6.0
Rnor_5.0712,975,444 - 12,975,612UniSTSRnor5.0
RGSC_v3.4711,437,569 - 11,437,737UniSTSRGSC3.4
Celera78,097,405 - 8,097,573UniSTS
RH 3.4 Map746.9UniSTS
Cytogenetic Map7q11UniSTS
RH139332  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,924,674 - 9,924,899 (+)MAPPERmRatBN7.2
Rnor_6.0712,806,036 - 12,806,260NCBIRnor6.0
Rnor_5.0712,976,240 - 12,976,464UniSTSRnor5.0
RGSC_v3.4711,438,365 - 11,438,589UniSTSRGSC3.4
Celera78,098,201 - 8,098,425UniSTS
Cytogenetic Map7q11UniSTS


Genetic Models
This gene Fstl3 is modified in the following models/strains:
SD-Fstl3em1Soar    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 152 91 90 59 37 59 6 298 137 11 131 78 92 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000012578   ⟹   ENSRNOP00000012578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,574,186 - 10,579,844 (-)Ensembl
mRatBN7.2 Ensembl79,923,576 - 9,929,216 (-)Ensembl
Rnor_6.0 Ensembl712,804,919 - 12,810,570 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109931   ⟹   ENSRNOP00000090726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,574,195 - 10,590,509 (-)Ensembl
mRatBN7.2 Ensembl79,923,576 - 9,939,639 (-)Ensembl
RefSeq Acc Id: NM_053629   ⟹   NP_446081
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,574,195 - 10,579,844 (-)NCBI
mRatBN7.279,923,574 - 9,929,223 (-)NCBI
Dahl_SR_JrHsd713,322,213 - 13,327,856 (-)NCBI
Lyon_Normotensive713,485,663 - 13,491,306 (-)NCBI
Lyon_Hypertensive713,560,510 - 13,566,153 (-)NCBI
F344_StmMcwi711,926,314 - 11,931,957 (-)NCBI
Rnor_6.0712,806,031 - 12,810,556 (-)NCBI
Rnor_5.0712,976,235 - 12,980,760 (-)NCBI
RGSC_v3.4711,438,360 - 11,442,885 (-)RGD
Celera78,098,196 - 8,102,721 (-)RGD
Sequence:
RefSeq Acc Id: XM_063262862   ⟹   XP_063118932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,574,196 - 10,579,564 (-)NCBI
Protein Sequences
Protein RefSeqs NP_446081 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118932 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB32664 (Get FASTA)   NCBI Sequence Viewer  
  BAC16229 (Get FASTA)   NCBI Sequence Viewer  
  EDL89395 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012578
  ENSRNOP00000012578.3
GenBank Protein Q99PW7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446081   ⟸   NM_053629
- Peptide Label: precursor
- UniProtKB: Q54A93 (UniProtKB/Swiss-Prot),   Q99PW7 (UniProtKB/Swiss-Prot),   A6K8X5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012578   ⟸   ENSRNOT00000012578
Ensembl Acc Id: ENSRNOP00000090726   ⟸   ENSRNOT00000109931
RefSeq Acc Id: XP_063118932   ⟸   XM_063262862
- Peptide Label: isoform X1
Protein Domains
Follistatin-like   Kazal-like   TB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PW7-F1-model_v2 AlphaFold Q99PW7 1-256 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695051
Promoter ID:EPDNEW_R5576
Type:multiple initiation site
Name:Fstl3_1
Description:follistatin like 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,810,584 - 12,810,644EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621811 AgrOrtholog
BioCyc Gene G2FUF-34888 BioCyc
Ensembl Genes ENSRNOG00000009311 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012578 ENTREZGENE
  ENSRNOT00000012578.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.60.30 UniProtKB/Swiss-Prot
  3.90.290.10 UniProtKB/Swiss-Prot
InterPro Fol_N UniProtKB/Swiss-Prot
  Follistatin/Osteonectin_EGF UniProtKB/Swiss-Prot
  Kazal_dom UniProtKB/Swiss-Prot
  Kazal_dom_sf UniProtKB/Swiss-Prot
  Prot_Inhib_GrowthFact_Antg UniProtKB/Swiss-Prot
  TB_dom UniProtKB/Swiss-Prot
  TB_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:114031 UniProtKB/Swiss-Prot
NCBI Gene 114031 ENTREZGENE
PANTHER FOLLISTATIN, ISOFORM A-RELATED UniProtKB/Swiss-Prot
  FOLLISTATIN-RELATED UniProtKB/Swiss-Prot
Pfam FOLN UniProtKB/Swiss-Prot
  FST_N UniProtKB/Swiss-Prot
  Kazal_2 UniProtKB/Swiss-Prot
PhenoGen Fstl3 PhenoGen
PROSITE KAZAL_2 UniProtKB/Swiss-Prot
  PS51364 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009311 RatGTEx
SMART FOLN UniProtKB/Swiss-Prot
  KAZAL UniProtKB/Swiss-Prot
Superfamily-SCOP SSF100895 UniProtKB/Swiss-Prot
  SSF57581 UniProtKB/Swiss-Prot
UniProt A0A8I6AEC7_RAT UniProtKB/TrEMBL
  A6K8X5 ENTREZGENE, UniProtKB/TrEMBL
  FSTL3_RAT UniProtKB/Swiss-Prot
  Q54A93 ENTREZGENE
  Q99PW7 ENTREZGENE
UniProt Secondary Q54A93 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Fstl3  follistatin like 3  Fstl3  follistatin-like 3 (secreted glycoprotein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Fstl3  follistatin-like 3 (secreted glycoprotein)  Fstl3  follistatin-like 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Fstl3  follistatin-like 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Fstl3  follistatin-like 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression abundantly expressed in the adrenal gland and testis 1302294