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Gene: Samsn1 (SAM domain, SH3 domain and nuclear localization signals, 1) Rattus norvegicus

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Symbol:

Samsn1

Name:

SAM domain, SH3 domain and nuclear localization signals, 1

RGD ID:

620926

Description:

Predicted to enable phosphotyrosine residue binding activity. Predicted to be involved in negative regulation of B cell activation; negative regulation of adaptive immune response; and regulation of intracellular signal transduction. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Orthologous to human SAMSN1 (SAM domain, SH3 domain and nuclear localization signals 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Nash; SAM domain, SH3 domain and nuclear localisation signals, 1; SAM domain-containing protein SAMSN-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	27,971,565 - 28,021,944 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	27,970,564 - 28,021,944 (-)	Ensembl				GRCr8
mRatBN7.2	11	14,484,523 - 14,534,900 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	14,483,893 - 14,534,900 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	23,110,271 - 23,160,500 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	15,836,651 - 15,886,876 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	15,004,507 - 15,054,732 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	14,252,088 - 14,405,825 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	14,253,848 - 14,304,725 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	17,910,040 - 17,960,596 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	14,633,494 - 14,683,788 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	14,497,563 - 14,547,805 (-)	NCBI		Celera
RGSC_v3.1	11	14,633,493 - 14,683,788 (-)	NCBI
Cytogenetic Map	11	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4-hydroxynon-2-enal (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

copper(II) chloride (ISO)

Dibutyl phosphate (ISO)

dimethylarsinic acid (ISO)

dioxygen (ISO)

flavonoids (EXP)

formaldehyde (ISO)

Heliotrine (EXP)

isotretinoin (ISO)

methylarsonic acid (ISO)

naled (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

Senkirkine (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

testosterone (EXP)

titanium dioxide (ISO)

topotecan (EXP)

triclosan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

XL147 (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of adaptive immune response (IEA,ISO)

negative regulation of B cell activation (IBA,IEA,ISO)

negative regulation of peptidyl-tyrosine phosphorylation (ISO)

regulation of intracellular signal transduction (IBA)

Cellular Component

cytoplasm (IBA,IEA)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

ruffle (IEA)

Molecular Function

phosphotyrosine residue binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	HACS1 encodes a novel SH3-SAM adaptor protein differentially expressed in normal and malignant hematopoietic cells.	Claudio JO, etal., Oncogene 2001 Aug 30;20(38):5373-7.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11594764	PMID:15381729	PMID:19923443	PMID:20478393	PMID:22658674

Genomics

Comparative Map Data

Samsn1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	27,971,565 - 28,021,944 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	27,970,564 - 28,021,944 (-)	Ensembl				GRCr8
mRatBN7.2	11	14,484,523 - 14,534,900 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	14,483,893 - 14,534,900 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	23,110,271 - 23,160,500 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	15,836,651 - 15,886,876 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	15,004,507 - 15,054,732 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	14,252,088 - 14,405,825 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	14,253,848 - 14,304,725 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	17,910,040 - 17,960,596 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	14,633,494 - 14,683,788 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	14,497,563 - 14,547,805 (-)	NCBI		Celera
RGSC_v3.1	11	14,633,493 - 14,683,788 (-)	NCBI
Cytogenetic Map	11	p11	NCBI

SAMSN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	14,485,228 - 14,659,417 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	14,485,228 - 14,658,821 (-)	Ensembl			hg38	GRCh38
GRCh37	21	15,857,549 - 16,031,738 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	14,779,420 - 14,840,535 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	21	14,779,419 - 14,840,535	NCBI
Celera	21	1,027,395 - 1,088,492 (-)	NCBI		Celera
Cytogenetic Map	21	q11.2	NCBI
HuRef	21	1,240,511 - 1,338,520 (-)	NCBI		HuRef
CHM1_1	21	15,418,089 - 15,516,274 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	21	12,840,563 - 13,014,732 (-)	NCBI		T2T-CHM13v2.0

Samsn1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	75,655,682 - 75,706,154 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	75,655,681 - 75,819,169 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	75,858,794 - 75,909,266 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	75,858,793 - 76,022,281 (-)	Ensembl			mm10	GRCm38
MGSCv37	16	75,859,039 - 75,909,511 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	75,741,474 - 75,791,946 (-)	NCBI		MGSCv36	mm8
Celera	16	76,082,014 - 76,131,797 (-)	NCBI		Celera
Cytogenetic Map	16	C3.1	NCBI
cM Map	16	43.36	NCBI

Samsn1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	16,329,288 - 16,378,062 (-)	Ensembl
ChiLan1.0	NW_004955407	16,329,838 - 16,377,763 (-)	NCBI	ChiLan1.0	ChiLan1.0

SAMSN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	10,979,161 - 11,149,950 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	5,812,917 - 5,983,746 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	1,228,632 - 1,399,331 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	14,595,688 - 14,703,600 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	14,595,688 - 14,711,613 (-)	Ensembl			panPan2	panpan1.1

SAMSN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	11,485,964 - 11,756,275 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	11,486,649 - 11,754,607 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	11,497,136 - 11,766,896 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	11,510,963 - 11,781,247 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	11,510,981 - 11,781,296 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	11,484,017 - 11,753,288 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	11,521,549 - 11,791,326 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	11,917,912 - 12,187,664 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Samsn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	12,580,579 - 12,671,795 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936505	7,499,719 - 7,550,679 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936505	7,499,801 - 7,591,566 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SAMSN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	179,428,779 - 179,556,447 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	179,431,494 - 179,509,359 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	189,668,581 - 189,798,767 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SAMSN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	77,870,604 - 78,038,215 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	77,937,984 - 78,038,199 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	75,882,004 - 76,050,679 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Samsn1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	2,977,395 - 3,022,694 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624745	2,977,401 - 3,022,606 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Samsn1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	66,078,891 - 66,129,642 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Samsn1
531 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	103
Count of miRNA genes:	86
Interacting mature miRNAs:	93
Transcripts:	ENSRNOT00000040202
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
2290451	Scl58	Serum cholesterol level QTL 58	3.48		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	11	26318031	55806125	Rat
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	3818154	48818154	Rat
1600394	Edcs1	Endometrial carcinoma susceptibility QTL1	2.9	0.04	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	11	12823152	57823152	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
634339	Niddm50	Non-insulin dependent diabetes mellitus QTL 50	3.32		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	10806125	55806125	Rat
631510	Spl2	Serum phospholipid level QTL 2	4.1		blood phospholipid amount (VT:0006084)	serum phospholipid level (CMO:0001171)	11	27556685	72556685	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
19	12	82	207	91	90	59	132	59	6	440	255	21	183	99	121	31	31	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_130821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB067679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000040202 ⟹ ENSRNOP00000039751

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	14,483,893 - 14,516,391 (-)	Ensembl
Rnor_6.0 Ensembl	11	14,254,047 - 14,304,603 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082143 ⟹ ENSRNOP00000074870

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	27,970,564 - 28,021,944 (-)	Ensembl
mRatBN7.2 Ensembl	11	14,483,893 - 14,534,900 (-)	Ensembl
Rnor_6.0 Ensembl	11	14,253,848 - 14,304,725 (-)	Ensembl

RefSeq Acc Id:

NM_130821 ⟹ NP_570834

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	27,971,565 - 28,021,944 (-)	NCBI
mRatBN7.2	11	14,484,523 - 14,534,900 (-)	NCBI
Rnor_6.0	11	14,254,047 - 14,304,685 (-)	NCBI
Rnor_5.0	11	17,910,040 - 17,960,596 (-)	NCBI
RGSC_v3.4	11	14,633,494 - 14,683,788 (-)	RGD
Celera	11	14,497,563 - 14,547,805 (-)	NCBI

Sequence:

show sequence

ATCACGAACAGTAACGGTGCCTGCTCTCAGAGGTCTCTGTAAGAGCAGAACCTGTACTTACTAG
AGGTGGCCTGAAGTCAAAATGCTAAAGAGGAAGCCATCCAATGCTTCAGAGAAGGAGAAACACC
AAAAACCGAAGCGCAGCAGCAGTTTTGGGAATTTTGATCGTTTTCGGAATAATTCCATATCAAA
ATCTGATGACTCAATCGAGGTCCGTGACGGGGAACTGACAAATGGAAGTGAGGAACAAAGCAAA
ACTTCAAACAATGGAGGAAGTCTAGGTAAAAAAGTGAGGGCTATTTCATGGACAATGAAGAAAA
AAGTAGGGAAAAAATACATCAAAGCTCTTTCTGAGGAAAAAGAGGAGGAAATTAGAGAGGAAAC
CCTCCAGTATCGGAACAGTGATCCCATGATTGGAACACGTACAGAGAAGATCTCTCTTAAAGCC
AGCGACTCTATGGACAGTCTTTACAGTGGGCAGAGCTCATCAAGTGGGATAACAAACTGTTCAG
ATGGAACAAGCAATCGGGACAGCTTTCGACTGGACGACGACAGCCCCTACTCAGGGCCATTCTG
TGGCCGTGCCCGAGTGCACACAGACTTCACACCAAGTCCCTATGACACAGACTCCCTTAAAATC
AAGAAAGGAGACATCATAGACATTATCTGCAAAACACCGATGGGAATGTGGACAGGGATGCTAA
ACAACAAAGTGGGGAACTTCAAGTTCATTTACGTGGATGTTATCTCAGAAGAGGAAGCAGCTCC
TAAGAAAGTAAAGGTGCCCAGAAGCAGTAGAAGAGAAAACCCCCAGACTCTCCAAGAATTCTTA
GAGAGGATTCATCTTCAGGAATATACTTCAGCATTTCTGCTCAATGGTTATGAGGCCCTGGATG
ACTTGAAGGATATCAAAGAAAGCCATCTAATTGAACTAAACATTGCCAATCCAGAAGACAGGGC
GAGGCTCCTGTCTGCTGCTGAGAGTCTCCTGGATGAAGAAACTGCCGCGGAGCATGAAGAGGAA
CCTGTGCCTCTGTCCTCAAACCCAGACATCTTGAGTGAATCACAGTTAGATGACTGCCCGAGGG
ACTCTGGCTGTTACATCTCATCAGGAAATTCAGATAATGGCAAAGAAGATCCAGAGTCCCAAAG
TCTGCCTGACATGGTACAGAAGATTTCCATCACGGAGCCCAGTGACTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_570834	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB84358	(Get FASTA)	NCBI Sequence Viewer
	EDM10583	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074870
	ENSRNOP00000074870.1

RefSeq Acc Id:

NP_570834 ⟸ NM_130821

- UniProtKB:

A0A0G2K960 (UniProtKB/TrEMBL), A6JL18 (UniProtKB/TrEMBL), G3V993 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLKRKPSNASEKEKHQKPKRSSSFGNFDRFRNNSISKSDDSIEVRDGELTNGSEEQSKTSNNGG
SLGKKVRAISWTMKKKVGKKYIKALSEEKEEEIREETLQYRNSDPMIGTRTEKISLKASDSMDS
LYSGQSSSSGITNCSDGTSNRDSFRLDDDSPYSGPFCGRARVHTDFTPSPYDTDSLKIKKGDII
DIICKTPMGMWTGMLNNKVGNFKFIYVDVISEEEAAPKKVKVPRSSRRENPQTLQEFLERIHLQ
EYTSAFLLNGYEALDDLKDIKESHLIELNIANPEDRARLLSAAESLLDEETAAEHEEEPVPLSS
NPDILSESQLDDCPRDSGCYISSGNSDNGKEDPESQSLPDMVQKISITEPSD

hide sequence

Ensembl Acc Id:

ENSRNOP00000074870 ⟸ ENSRNOT00000082143

Ensembl Acc Id:

ENSRNOP00000039751 ⟸ ENSRNOT00000040202

Protein Domains

SAM SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K960-F1-model_v2	AlphaFold	A0A0G2K960	1-372	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698005

Promoter ID:

EPDNEW_R8530

Type:

single initiation site

Name:

Samsn1_1

Description:

SAM domain, SH3 domain and nuclear localization signals, 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	14,304,696 - 14,304,756	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620926	AgrOrtholog
BioCyc Gene	G2FUF-22222	BioCyc
Ensembl Genes	ENSRNOG00000030930	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082143	ENTREZGENE
	ENSRNOT00000082143.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.50	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	rSAM/SH3_domain-containing	UniProtKB/TrEMBL
	SAM	UniProtKB/TrEMBL
	SAM-SH3_domain_protein	UniProtKB/TrEMBL
	SAM/pointed	UniProtKB/TrEMBL
	SAMSN1_SAM	UniProtKB/TrEMBL
	SH3-like_dom	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
KEGG Report	rno:170637	UniProtKB/TrEMBL
NCBI Gene	170637	ENTREZGENE
PANTHER	SAM DOMAIN-CONTAINING PROTEIN SAMSN-1	UniProtKB/TrEMBL
	SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED	UniProtKB/TrEMBL
Pfam	SAM_2	UniProtKB/TrEMBL
	SH3_2	UniProtKB/TrEMBL
	SLY	UniProtKB/TrEMBL
PhenoGen	Samsn1	PhenoGen
PROSITE	SAM_DOMAIN	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030930	RatGTEx
SMART	SAM	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
Superfamily-SCOP	SAM_homology	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
UniProt	A0A0G2K960	ENTREZGENE, UniProtKB/TrEMBL
	A6JL18	ENTREZGENE, UniProtKB/TrEMBL
	G3V993	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Samsn1	SAM domain, SH3 domain and nuclear localisation signals, 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Samsn1	SAM domain, SH3 domain and nuclear localisation signals, 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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