Ppp2r2c (protein phosphatase 2, regulatory subunit B, gamma) - Rat Genome Database

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Gene: Ppp2r2c (protein phosphatase 2, regulatory subunit B, gamma) Rattus norvegicus
Analyze
Symbol: Ppp2r2c
Name: protein phosphatase 2, regulatory subunit B, gamma
RGD ID: 620920
Description: Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Orthologous to human PPP2R2C (protein phosphatase 2 regulatory subunit Bgamma); PARTICIPATES IN Chagas disease pathway; hepatitis C pathway; mRNA decay pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103693768; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform BRgamma; PP2A subunit B isoform gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A, subunit B, B-gamma isoform; PP2A, subunit B, B55-gamma isoform; PP2A, subunit B, BRgamma isoform; PP2A, subunit B, PR55-gamma isoform; PP2A, subunit B, R2-gamma isoform; Pr52; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81478,071,274 - 78,156,212 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1478,071,274 - 78,156,212 (-)EnsemblGRCr8
mRatBN7.21473,846,547 - 73,931,489 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,846,547 - 73,931,864 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1478,290,391 - 78,372,505 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,531,243 - 79,613,368 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,976,206 - 76,058,325 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,679,214 - 78,763,175 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,679,214 - 78,902,063 (-)Ensemblrn6Rnor6.0
Rnor_5.01478,644,679 - 78,727,963 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41479,417,924 - 79,460,075 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1472,795,578 - 72,821,075 (-)NCBICelera
RGSC_v3.11479,420,314 - 79,518,305 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Emphysema  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-methylcholine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
Cuprizon  (EXP)
diarsenic trioxide  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
levonorgestrel  (ISO)
maneb  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
testosterone undecanoate  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. cDNA cloning of BR gamma, a novel brain-specific isoform of the B regulatory subunit of type-2A protein phosphatase. Akiyama N, etal., Eur J Biochem 1995 Jun 1;230(2):766-72.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Overexpression of the protein phosphatase 2A regulatory subunit Bgamma promotes neuronal differentiation by activating the MAP kinase (MAPK) cascade. Strack S J Biol Chem 2002 Nov 1;277(44):41525-32.
Additional References at PubMed
PMID:12644453   PMID:34635097  


Genomics

Comparative Map Data
Ppp2r2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81478,071,274 - 78,156,212 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1478,071,274 - 78,156,212 (-)EnsemblGRCr8
mRatBN7.21473,846,547 - 73,931,489 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1473,846,547 - 73,931,864 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1478,290,391 - 78,372,505 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01479,531,243 - 79,613,368 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01475,976,206 - 76,058,325 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01478,679,214 - 78,763,175 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1478,679,214 - 78,902,063 (-)Ensemblrn6Rnor6.0
Rnor_5.01478,644,679 - 78,727,963 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41479,417,924 - 79,460,075 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1472,795,578 - 72,821,075 (-)NCBICelera
RGSC_v3.11479,420,314 - 79,518,305 (-)NCBI
Cytogenetic Map14q21NCBI
PPP2R2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3846,320,581 - 6,563,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl46,320,578 - 6,563,600 (-)Ensemblhg38GRCh38
GRCh3746,322,308 - 6,565,526 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3646,373,206 - 6,525,227 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3446,440,377 - 6,501,669NCBI
Celera46,223,017 - 6,284,392 (-)NCBICelera
Cytogenetic Map4p16.1NCBI
HuRef46,255,749 - 6,490,033 (-)NCBIHuRef
CHM1_146,320,256 - 6,563,374 (-)NCBICHM1_1
T2T-CHM13v2.046,294,675 - 6,540,171 (-)NCBIT2T-CHM13v2.0
Ppp2r2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39537,024,187 - 37,112,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl537,025,857 - 37,112,422 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38536,866,846 - 36,955,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl536,868,513 - 36,955,078 (+)Ensemblmm10GRCm38
MGSCv37537,259,809 - 37,346,317 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36537,156,819 - 37,243,327 (+)NCBIMGSCv36mm8
Celera534,374,910 - 34,406,862 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map519.28NCBI
Ppp2r2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555143,863,921 - 3,890,779 (+)Ensembl
ChiLan1.0NW_0049555143,863,461 - 3,893,026 (+)NCBIChiLan1.0ChiLan1.0
PPP2R2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v236,592,133 - 6,835,224 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan146,520,973 - 6,764,117 (-)NCBINHGRI_mPanPan1
PanPan1.146,396,200 - 6,609,737 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl46,393,840 - 6,609,682 (-)EnsemblpanPan2panpan1.1
PPP2R2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1358,477,762 - 58,611,670 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl358,480,553 - 58,611,852 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha361,169,120 - 61,302,657 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0358,945,620 - 59,079,372 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl358,945,625 - 59,079,319 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1358,442,036 - 58,575,715 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0358,649,826 - 58,783,791 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0358,999,153 - 59,132,725 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp2r2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528564,671,734 - 64,768,963 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647718,371,872 - 18,470,661 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647718,372,253 - 18,470,655 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl84,218,823 - 4,352,039 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.184,218,228 - 4,352,043 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.282,881,355 - 2,896,725 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12742,449,615 - 42,691,826 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2742,449,619 - 42,598,391 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604789,242,916 - 89,489,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475522,854,961 - 22,933,126 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475522,855,269 - 22,933,149 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp2r2c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11168,195,668 - 68,280,249 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppp2r2c
407 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:54
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000007293
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 11 58 160 65 64 34 33 34 6 256 121 9 141 79 92 30 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000088469   ⟹   ENSRNOP00000073589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1478,095,785 - 78,156,212 (-)Ensembl
mRatBN7.2 Ensembl1473,871,059 - 73,931,236 (-)Ensembl
Rnor_6.0 Ensembl1478,685,078 - 78,902,063 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091927   ⟹   ENSRNOP00000070068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1473,846,547 - 73,876,290 (-)Ensembl
Rnor_6.0 Ensembl1478,679,214 - 78,707,861 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102952   ⟹   ENSRNOP00000086629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1478,071,274 - 78,101,556 (-)Ensembl
mRatBN7.2 Ensembl1473,846,547 - 73,876,830 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109354   ⟹   ENSRNOP00000085341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1478,071,274 - 78,156,212 (-)Ensembl
mRatBN7.2 Ensembl1473,846,547 - 73,931,864 (-)Ensembl
RefSeq Acc Id: NM_001412427   ⟹   NP_001399356
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81478,071,274 - 78,156,212 (-)NCBI
mRatBN7.21473,846,547 - 73,931,489 (-)NCBI
RefSeq Acc Id: NM_057116   ⟹   NP_476457
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81478,071,274 - 78,156,212 (-)NCBI
mRatBN7.21473,846,547 - 73,931,489 (-)NCBI
Rnor_6.01478,679,214 - 78,763,175 (-)NCBI
Rnor_5.01478,644,679 - 78,727,963 (-)NCBI
RGSC_v3.41479,417,924 - 79,460,075 (-)RGD
Celera1472,795,578 - 72,821,075 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272809   ⟹   XP_063128879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81478,071,274 - 78,147,864 (-)NCBI
RefSeq Acc Id: XM_063272810   ⟹   XP_063128880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81478,071,274 - 78,155,028 (-)NCBI
RefSeq Acc Id: NP_476457   ⟸   NM_057116
- Peptide Label: isoform 1
- UniProtKB: P97888 (UniProtKB/Swiss-Prot),   A0A0G2JWY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070068   ⟸   ENSRNOT00000091927
Ensembl Acc Id: ENSRNOP00000073589   ⟸   ENSRNOT00000088469
Ensembl Acc Id: ENSRNOP00000085341   ⟸   ENSRNOT00000109354
Ensembl Acc Id: ENSRNOP00000086629   ⟸   ENSRNOT00000102952
RefSeq Acc Id: NP_001399356   ⟸   NM_001412427
- Peptide Label: isoform 2
- UniProtKB: A0A8I6GCS7 (UniProtKB/TrEMBL),   A0A8I6A1K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128880   ⟸   XM_063272810
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128879   ⟸   XM_063272809
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JWY9 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97888-F1-model_v2 AlphaFold P97888 1-447 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620920 AgrOrtholog
BioCyc Gene G2FUF-15349 BioCyc
Ensembl Genes ENSRNOG00000058202 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000102952 ENTREZGENE
  ENSRNOT00000109354 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
InterPro PP2A_PR55 UniProtKB/Swiss-Prot
  PP2A_PR55_CS UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:117256 UniProtKB/Swiss-Prot
NCBI Gene 117256 ENTREZGENE
PANTHER PTHR11871 UniProtKB/Swiss-Prot
PhenoGen Ppp2r2c PhenoGen
PIRSF PP2A_PR55 UniProtKB/Swiss-Prot
PRINTS PP2APR55 UniProtKB/Swiss-Prot
PROSITE PR55_1 UniProtKB/Swiss-Prot
  PR55_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000058202 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt 2ABG_RAT UniProtKB/Swiss-Prot
  A0A0G2JWY9 ENTREZGENE
  A0A0G2K5X0_RAT UniProtKB/TrEMBL
  A0A8I6A1K8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GCS7 ENTREZGENE, UniProtKB/TrEMBL
  A6IJW8_RAT UniProtKB/TrEMBL
  P97888 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ppp2r2c  protein phosphatase 2, regulatory subunit B, gamma  LOC103693768  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform-like  Data merged from RGD:9103852 737654 PROVISIONAL
2014-08-25 LOC103693768  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-08-02 Ppp2r2c  protein phosphatase 2, regulatory subunit B, gamma  Ppp2r2c  protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Ppp2r2c  protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform  Ppp2r2c  protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ppp2r2c  protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ppp2r2c  protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function a brain specific subunit of protein serine/threonine phosphatase 2A 729538