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Gene: Hspbap1 (HSPB1 associated protein 1) Rattus norvegicus

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Symbol:

Hspbap1

Name:

HSPB1 associated protein 1

RGD ID:

620870

Description:

Predicted to enable 2-oxoglutarate-dependent dioxygenase activity. Predicted to be located in cytoplasm. Orthologous to human HSPBAP1 (HSPB1 associated protein 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

27 KdA heat shock protein-associated protein 1; Hspb associated protein 1; HSPB1-associated protein 1; Pass1; protein associated with small stress protein 1; protein associating with small stress protein PASS1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HSPBAP1 (HSPB1 associated protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Hspbap1 (Hspb associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hspbap1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HSPBAP1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HSPBAP1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hspbap1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HSPBAP1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HSPBAP1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hspbap1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Hspbap1 (HSPB1 associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Hspbap1 (Hspb associated protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	HSPBAP1 (HSPB1 associated protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hspbap1 (hspb associated protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	HSPBAP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	HSPBAP1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hspbap1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hspbap1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,445,376 - 78,500,034 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	78,445,376 - 78,500,034 (-)	Ensembl				GRCr8
mRatBN7.2	11	64,940,089 - 64,994,753 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,940,091 - 64,994,756 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	73,762,126 - 73,816,710 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,424,391 - 66,478,975 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,455,648 - 65,510,232 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	80,338,006 - 80,392,710 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	78,523,013 - 78,577,713 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	79,467,475 - 79,522,175 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	78,299,534 - 78,354,106 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	68,142,684 - 68,197,783 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	68,141,342 - 68,197,834 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	71,232,155 - 71,287,075 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	66,774,152 - 66,828,789 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	64,402,375 - 64,457,091 (-)	NCBI		Celera
RGSC_v3.1	11	66,831,742 - 66,886,367 (-)	NCBI
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (EXP)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cisplatin (ISO)

clofibric acid (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cypermethrin (ISO)

Dibutyl phosphate (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

glyphosate (ISO)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

quercetin (ISO)

resveratrol (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

Testosterone propionate (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IEA)

Molecular Function

2-oxoglutarate-dependent dioxygenase activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27.	Liu C, etal., J Biol Chem 2000 Jun 23;275(25):18724-31.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Hspbap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,445,376 - 78,500,034 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	78,445,376 - 78,500,034 (-)	Ensembl				GRCr8
mRatBN7.2	11	64,940,089 - 64,994,753 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,940,091 - 64,994,756 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	73,762,126 - 73,816,710 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,424,391 - 66,478,975 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,455,648 - 65,510,232 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	80,338,006 - 80,392,710 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	78,523,013 - 78,577,713 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	79,467,475 - 79,522,175 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	78,299,534 - 78,354,106 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	68,142,684 - 68,197,783 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	68,141,342 - 68,197,834 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	71,232,155 - 71,287,075 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	66,774,152 - 66,828,789 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	64,402,375 - 64,457,091 (-)	NCBI		Celera
RGSC_v3.1	11	66,831,742 - 66,886,367 (-)	NCBI
Cytogenetic Map	11	q22	NCBI

HSPBAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	122,739,999 - 122,793,831 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	122,739,981 - 122,793,831 (-)	Ensembl			hg38	GRCh38
GRCh37	3	122,458,846 - 122,512,678 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	123,941,536 - 123,995,340 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	123,941,535 - 123,995,340	NCBI
Celera	3	120,868,679 - 120,922,738 (-)	NCBI		Celera
Cytogenetic Map	3	q21.1	NCBI
HuRef	3	119,832,121 - 119,886,049 (-)	NCBI		HuRef
CHM1_1	3	122,422,413 - 122,476,340 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	125,459,253 - 125,513,020 (-)	NCBI		T2T-CHM13v2.0

Hspbap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	35,590,009 - 35,648,832 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	35,590,745 - 35,648,847 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	35,769,726 - 35,828,462 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	35,770,375 - 35,828,477 (+)	Ensembl			mm10	GRCm38
MGSCv37	16	35,770,472 - 35,828,548 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	35,690,167 - 35,745,311 (+)	NCBI		MGSCv36	mm8
Celera	16	36,244,106 - 36,308,358 (+)	NCBI		Celera
Cytogenetic Map	16	B3	NCBI
cM Map	16	25.43	NCBI

Hspbap1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	21,931,502 - 22,004,807 (-)	Ensembl
ChiLan1.0	NW_004955427	21,931,101 - 22,004,811 (-)	NCBI	ChiLan1.0	ChiLan1.0

HSPBAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	120,669,988 - 120,740,228 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	120,669,032 - 120,745,007 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	119,832,903 - 119,883,383 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	126,737,418 - 126,786,492 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	126,737,419 - 126,786,484 (-)	Ensembl			panPan2	panpan1.1

HSPBAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	25,803,224 - 25,868,587 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	25,803,503 - 25,868,174 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	25,827,401 - 25,892,410 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	26,036,867 - 26,101,790 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	26,036,965 - 26,101,347 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	25,834,787 - 25,899,215 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	25,877,303 - 25,941,617 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	26,436,429 - 26,501,162 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Hspbap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	128,483,687 - 128,545,381 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936536	8,976,625 - 8,994,974 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HSPBAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	137,740,396 - 137,809,527 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	137,739,144 - 137,805,990 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	147,362,832 - 147,426,683 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HSPBAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	58,081,374 - 58,131,789 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	58,081,832 - 58,132,236 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	108,219,124 - 108,268,299 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hspbap1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624912	1,023,567 - 1,100,937 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624912	1,023,981 - 1,102,153 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Hspbap1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	20,547,448 - 20,602,990 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Hspbap1
342 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	2
Count of miRNA genes:	2
Interacting mature miRNAs:	2
Transcripts:	ENSRNOT00000003060
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	22524746	82951192	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	46443168	91443168	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	73308487	96070872	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	32943067	89836615	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	36428416	81428416	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	34618760	79618760	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	54415391	96071021	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	58931822	92356038	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	57754837	96071021	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	20193549	96351019	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	36749459	81749459	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	36749459	81749459	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	36749459	81749459	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	58272363	96350770	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	51071021	96071021	Rat

Markers in Region

D11Got43

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	64,955,286 - 64,955,431 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	68,158,143 - 68,158,287	NCBI	Rnor6.0
Rnor_5.0	11	71,247,614 - 71,247,758	UniSTS	Rnor5.0
RGSC_v3.4	11	66,789,349 - 66,789,494	RGD	RGSC3.4
RGSC_v3.4	11	66,789,350 - 66,789,494	UniSTS	RGSC3.4
Celera	11	64,417,577 - 64,417,721	UniSTS
RGSC_v3.1	11	66,846,939 - 66,847,083	RGD
RH 3.4 Map	11	443.5	UniSTS
RH 3.4 Map	11	443.5	RGD
RH 2.0 Map	11	179.0	RGD
Cytogenetic Map	11	q22	UniSTS

D11Got44

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	64,950,971 - 64,951,146 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	68,153,565 - 68,153,739	NCBI	Rnor6.0
Rnor_5.0	11	71,243,036 - 71,243,210	UniSTS	Rnor5.0
RGSC_v3.4	11	66,785,033 - 66,785,208	RGD	RGSC3.4
RGSC_v3.4	11	66,785,034 - 66,785,208	UniSTS	RGSC3.4
Celera	11	64,413,256 - 64,413,432	UniSTS
RGSC_v3.1	11	66,842,623 - 66,842,797	RGD
RH 3.4 Map	11	462.0	UniSTS
RH 3.4 Map	11	462.0	RGD
RH 2.0 Map	11	200.4	RGD
Cytogenetic Map	11	q22	UniSTS

RH137489

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	64,993,525 - 64,993,732 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	68,196,557 - 68,196,763	NCBI	Rnor6.0
Rnor_5.0	11	71,285,849 - 71,286,055	UniSTS	Rnor5.0
RGSC_v3.4	11	66,827,561 - 66,827,767	UniSTS	RGSC3.4
Celera	11	64,455,864 - 64,456,070	UniSTS
Cytogenetic Map	11	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_134419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF168362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003060 ⟹ ENSRNOP00000003060

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	78,445,376 - 78,500,034 (-)	Ensembl
mRatBN7.2 Ensembl	11	64,940,091 - 64,994,756 (-)	Ensembl
Rnor_6.0 Ensembl	11	68,142,693 - 68,197,772 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081875 ⟹ ENSRNOP00000073471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	11	68,141,342 - 68,197,834 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000139052 ⟹ ENSRNOP00000105141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	78,445,376 - 78,500,034 (-)	Ensembl

RefSeq Acc Id:

NM_134419 ⟹ NP_599246

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	78,445,376 - 78,500,034 (-)	NCBI
mRatBN7.2	11	64,940,091 - 64,994,753 (-)	NCBI
Dahl_SR_JrHsd	11	80,338,006 - 80,392,710 (-)	NCBI
Lyon_Normotensive	11	78,523,013 - 78,577,713 (-)	NCBI
Lyon_Hypertensive	11	79,467,475 - 79,522,175 (-)	NCBI
F344_StmMcwi	11	78,299,534 - 78,354,106 (-)	NCBI
Rnor_6.0	11	68,142,684 - 68,197,783 (-)	NCBI
Rnor_5.0	11	71,232,155 - 71,287,075 (-)	NCBI
RGSC_v3.4	11	66,774,152 - 66,828,789 (-)	RGD
Celera	11	64,402,375 - 64,457,091 (-)	RGD

Sequence:

show sequence

GCAGCAGATCCCGGTGCTACGCCTCACCTGGCGCTCTCTCCATCCTTGGCGCGATAACCATGGA
AGCAGGCTGCGAGGGGAGCTCGCCCCAGACCCTGGGCGAGAGAACTATGGGGGAGGAAGGTGAA
CGTGTCAAACCTTTTACACCAGAGAAAGCAAAAGAGGTTATAATGTCTTTACAGCAGCCTGCAA
TCTTCTGTAACATGGTTTTTGATTGGCCATCACGACACTGGACTGCGAAACACCTTTCTAAGGT
CTTGGAGGGCAAGCAGATACGATTCAGGATGGGCCTGAGAAGCACCGGCACAGTTCCTCAGTTT
GAAACCGAATGCAGTTACGTGGATGCTACACTTGAGGAGTTTTTGGCCTGGAACTGCGACCAGT
CTAGAATCTCTGGACCATTTAAAAAGTATGATCATTCCAAATTCTGGGCTTATGCTGACTATAA
ATATTTTGTCACTCTATTTGAGGACAAGACGGATGTTTTCCAGGAGGTGATGTGGTCTGATTTT
GGGTTTCCTGGAAGAAATGGACAAGAAAGTACATTGTGGATCGGATCCCTGGGAGCCCACACTC
CCTGTCATCTGGACTCCTATGGTTGCAACTTGGTATTCCAAGTACAAGGAAGGAAAAGATGGCA
TCTCTTTCCTCCTGAAGATACACCTTTCCTTTATCCAACCAGAATTCCTTACGAAGAATCTAGT
GTGTTCAGTAAAATCAATGTTGTCAACCCTGATTTAAAGCGTTTCCCTCAGTTCCAGAAAGCTC
GAAGACATATGGTCACACTGAGCCCAGGACAGGTTCTGTTTGTTCCCAGACACTGGTGGCATTA
TGTGGAGTCTCTTGATCCTGTCACCGTCAGTATAAACTCCTGGATTGAGCTGGAGGAGGACCAC
CTCGCCCGGGTGGAGGAGGCGGTCACCCGAATGCTCGTGTGCACACTGAAGACCGCAGAGGACC
CGCACCACCCCAGGACCTGGCTGAACCCCACTGAGGTTGAGGAAACGTCTCATGAAGTCAATAG
CTGCTACTTGAACAGTGCTGTCTGTGCATTTTTTGATCATTGTGAAAGAGCTAAAGAAGTAGAA
ATGCAAGCTCCGAGAGCAAACGGGGAGGAGCCGGGTGTGCAGGAGCACATGGAAGTGGAGCAGG
CGCGCGACCCGAGCTCCGATGTGGGGGCTGGGAAACAGGAGGCCGCGAGTCCGTTTGGCCCAGA
TCTGGTTCCTGTGACACCAGCATCGGAAGAGAGAGGAGGCGCACTGGAAGGAGACAGCCAGGAG
TGTACCAGCAGAAACGGAGAACACTGTGCAGAACTGCCCTGCGCCAGGAGGCAGCAAGCCAGTA
AAGGAGCACGCGCGGAGGCAGGGCAGTCGGCCCCGAGGTATCCTGTGGCGCCTTCTAGAGTCTT
CGTGTCCACGGATGACCTGCTGGACTGCTTAGTCAATCCACAAGTAACCAGGATGGTGGCCCAG
CTTTTGATACAAGGAAAAAGCTTGTGATACTTTTTAAATAACTTTTTAATTACTTTTAAATAAC
CTTTTAAAATATATTTTTAGAAATAATAA

hide sequence

RefSeq Acc Id:

XM_039087949 ⟹ XP_038943877

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	78,445,376 - 78,468,102 (-)	NCBI
mRatBN7.2	11	64,940,089 - 64,956,984 (-)	NCBI

RefSeq Acc Id:

XM_039087950 ⟹ XP_038943878

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	78,445,376 - 78,468,442 (-)	NCBI
mRatBN7.2	11	64,940,089 - 64,963,172 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_599246	(Get FASTA)	NCBI Sequence Viewer
	XP_038943877	(Get FASTA)	NCBI Sequence Viewer
	XP_038943878	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD48846	(Get FASTA)	NCBI Sequence Viewer
	AAH91125	(Get FASTA)	NCBI Sequence Viewer
	EDM11306	(Get FASTA)	NCBI Sequence Viewer
	EDM11307	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003060
	ENSRNOP00000003060.6
GenBank Protein	Q5BKC6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_599246 ⟸ NM_134419

- UniProtKB:

Q9R153 (UniProtKB/Swiss-Prot), Q5BKC6 (UniProtKB/Swiss-Prot), A6IRF3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAGCEGSSPQTLGERTMGEEGERVKPFTPEKAKEVIMSLQQPAIFCNMVFDWPSRHWTAKHLS
KVLEGKQIRFRMGLRSTGTVPQFETECSYVDATLEEFLAWNCDQSRISGPFKKYDHSKFWAYAD
YKYFVTLFEDKTDVFQEVMWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQVQGRKR
WHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFQKARRHMVTLSPGQVLFVPRHWW
HYVESLDPVTVSINSWIELEEDHLARVEEAVTRMLVCTLKTAEDPHHPRTWLNPTEVEETSHEV
NSCYLNSAVCAFFDHCERAKEVEMQAPRANGEEPGVQEHMEVEQARDPSSDVGAGKQEAASPFG
PDLVPVTPASEERGGALEGDSQECTSRNGEHCAELPCARRQQASKGARAEAGQSAPRYPVAPSR
VFVSTDDLLDCLVNPQVTRMVAQLLIQGKSL

hide sequence

Ensembl Acc Id:

ENSRNOP00000073471 ⟸ ENSRNOT00000081875

Ensembl Acc Id:

ENSRNOP00000003060 ⟸ ENSRNOT00000003060

RefSeq Acc Id:	XP_038943878 ⟸ XM_039087950
- Peptide Label:	isoform X2
- UniProtKB:	A6IRF4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038943877 ⟸ XM_039087949
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000105141 ⟸ ENSRNOT00000139052

Protein Domains

JmjC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BKC6-F1-model_v2	AlphaFold	Q5BKC6	1-479	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698193

Promoter ID:

EPDNEW_R8713

Type:

multiple initiation site

Name:

Hspbap1_1

Description:

HSPB1 associated protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	68,197,794 - 68,197,854	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620870	AgrOrtholog
BioCyc Gene	G2FUF-21203	BioCyc
Ensembl Genes	ENSRNOG00000002241	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000003060	ENTREZGENE
	ENSRNOT00000003060.7	UniProtKB/Swiss-Prot
Gene3D-CATH	Cupin	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7366096	IMAGE-MGC_LOAD
InterPro	Cupin_8	UniProtKB/Swiss-Prot
	HSPB1-associated_protein_1	UniProtKB/Swiss-Prot
	JmjC_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:171460	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108597	IMAGE-MGC_LOAD
NCBI Gene	171460	ENTREZGENE
PANTHER	HSPB1-ASSOCIATED PROTEIN 1	UniProtKB/Swiss-Prot
	HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED	UniProtKB/Swiss-Prot
Pfam	Cupin_8	UniProtKB/Swiss-Prot
PhenoGen	Hspbap1	PhenoGen
PRINTS	PASS1	UniProtKB/Swiss-Prot
PROSITE	JMJC	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000002241	RatGTEx
SMART	JmjC	UniProtKB/Swiss-Prot
Superfamily-SCOP	Clavaminate synthase-like	UniProtKB/Swiss-Prot
UniProt	A0A0H2UHA5_RAT	UniProtKB/TrEMBL
	A0ABK0LHP8_RAT	UniProtKB/TrEMBL
	A6IRF3	ENTREZGENE, UniProtKB/TrEMBL
	A6IRF4	ENTREZGENE, UniProtKB/TrEMBL
	HBAP1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9R153	ENTREZGENE
UniProt Secondary	Q9R153	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-02-01	Hspbap1	HSPB1 associated protein 1	Hspbap1	Hspb associated protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Hspbap1	Hspb associated protein 1	Pass1	protein associating with small stress protein PASS1	Symbol and Name updated	1299863	APPROVED
2002-08-07	Pass1	protein associating with small stress protein PASS1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	enriched in kidney and testis; present in brain, spleen, lung, and liver	633714
gene_protein	428 amino acids; 49 kDa; pI of 6.47	633714

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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