Fxyd5 (FXYD domain-containing ion transport regulator 5) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Fxyd5 (FXYD domain-containing ion transport regulator 5) Rattus norvegicus
Analyze
Symbol: Fxyd5
Name: FXYD domain-containing ion transport regulator 5
RGD ID: 620827
Description: Predicted to enable actin binding activity; cadherin binding activity; and ion channel regulator activity. Predicted to be involved in positive regulation of sodium ion export across plasma membrane. Predicted to be located in plasma membrane. Orthologous to human FXYD5 (FXYD domain containing ion transport regulator 5); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: oncoprotein induced transcript 2; RIC
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,395,327 - 95,404,722 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,395,146 - 95,405,364 (-)EnsemblGRCr8
mRatBN7.2186,267,937 - 86,277,329 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,267,406 - 86,277,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,688,184 - 91,697,726 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,154,329 - 100,163,871 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,446,461 - 93,456,003 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,464,853 - 89,474,450 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,464,860 - 89,474,252 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,620,335 - 90,629,734 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4186,076,279 - 86,085,681 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,636,897 - 80,646,373 (-)NCBICelera
RGSC_v3.1186,154,389 - 86,163,792 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-diaminotoluene  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clotrimazole  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
methimazole  (EXP)
Muraglitazar  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
O-methyleugenol  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylephrine  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
quercetin  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP,ISO)
tungsten  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Sweadner KJ and Rael E, Genomics 2000 Aug 15;68(1):41-56.
Additional References at PubMed
PMID:11756660   PMID:12477932   PMID:15489334   PMID:22085977   PMID:35042436  


Genomics

Comparative Map Data
Fxyd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,395,327 - 95,404,722 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,395,146 - 95,405,364 (-)EnsemblGRCr8
mRatBN7.2186,267,937 - 86,277,329 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,267,406 - 86,277,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,688,184 - 91,697,726 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,154,329 - 100,163,871 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,446,461 - 93,456,003 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,464,853 - 89,474,450 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,464,860 - 89,474,252 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,620,335 - 90,629,734 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4186,076,279 - 86,085,681 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,636,897 - 80,646,373 (-)NCBICelera
RGSC_v3.1186,154,389 - 86,163,792 (-)NCBI
Cytogenetic Map1q21NCBI
FXYD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,154,735 - 35,169,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,154,569 - 35,171,791 (+)Ensemblhg38GRCh38
GRCh371935,645,638 - 35,660,784 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,337,467 - 40,352,625 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1932,359,062 - 32,374,225 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,154,002 - 32,169,298 (+)NCBIHuRef
CHM1_11935,647,512 - 35,662,675 (+)NCBICHM1_1
T2T-CHM13v2.01937,699,360 - 37,714,531 (+)NCBIT2T-CHM13v2.0
Fxyd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,732,153 - 30,741,565 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,732,147 - 30,741,906 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38731,032,723 - 31,042,331 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl731,032,722 - 31,042,481 (-)Ensemblmm10GRCm38
MGSCv37731,817,742 - 31,827,341 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36730,741,498 - 30,750,894 (-)NCBIMGSCv36mm8
Celera725,600,304 - 25,609,849 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.29NCBI
Fxyd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554684,470,148 - 4,480,386 (+)NCBIChiLan1.0ChiLan1.0
FXYD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,166,684 - 41,182,021 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,150,032 - 43,165,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,100,475 - 32,115,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,838,920 - 40,854,027 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,839,798 - 40,854,027 (+)EnsemblpanPan2panpan1.1
FXYD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,412,878 - 117,424,052 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,219,880 - 117,423,703 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1116,815,681 - 116,827,381 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01118,012,584 - 118,024,310 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,012,481 - 118,024,313 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,575,239 - 117,586,935 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,200,574 - 117,212,269 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,257,017 - 118,268,732 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fxyd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,540,962 - 10,550,554 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365701,095,373 - 1,104,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FXYD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1644,682,245 - 44,696,088 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,131,800 - 40,145,611 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FXYD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,087,554 - 30,103,360 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,087,558 - 30,104,530 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660737,860,898 - 7,876,716 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fxyd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247948,347,925 - 8,359,215 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fxyd5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12164,989,414 - 164,999,135 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fxyd5
24 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:41
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000028597
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat

Markers in Region
D1Got428  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8195,397,046 - 95,397,324 (+)Marker Load Pipeline
mRatBN7.2186,269,653 - 86,269,931 (+)MAPPERmRatBN7.2
Rnor_6.0189,466,577 - 89,466,854NCBIRnor6.0
Rnor_5.0190,622,059 - 90,622,336UniSTSRnor5.0
RGSC_v3.4186,077,999 - 86,078,276UniSTSRGSC3.4
Cytogenetic Map1q21UniSTS
RH130316  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,277,824 - 86,278,018 (+)MAPPERmRatBN7.2
Rnor_6.0189,474,748 - 89,474,941NCBIRnor6.0
Rnor_5.0190,630,230 - 90,630,423UniSTSRnor5.0
RGSC_v3.4186,086,171 - 86,086,364UniSTSRGSC3.4
Celera180,646,869 - 80,647,062UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000028597   ⟹   ENSRNOP00000028597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,397,829 - 95,404,722 (-)Ensembl
mRatBN7.2 Ensembl186,270,436 - 86,277,519 (-)Ensembl
Rnor_6.0 Ensembl189,464,860 - 89,474,252 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089474   ⟹   ENSRNOP00000068919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,395,146 - 95,404,722 (-)Ensembl
mRatBN7.2 Ensembl186,267,934 - 86,277,288 (-)Ensembl
Rnor_6.0 Ensembl189,464,860 - 89,473,904 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117579   ⟹   ENSRNOP00000085788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,395,327 - 95,405,364 (-)Ensembl
mRatBN7.2 Ensembl186,267,406 - 86,277,519 (-)Ensembl
RefSeq Acc Id: NM_001270688   ⟹   NP_001257617
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,395,330 - 95,404,722 (-)NCBI
mRatBN7.2186,267,937 - 86,277,329 (-)NCBI
Rnor_6.0189,464,860 - 89,474,252 (-)NCBI
Rnor_5.0190,620,335 - 90,629,734 (-)NCBI
Celera180,636,897 - 80,646,373 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001270689   ⟹   NP_001257618
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,395,330 - 95,404,374 (-)NCBI
mRatBN7.2186,267,937 - 86,276,981 (-)NCBI
Rnor_6.0189,464,860 - 89,473,904 (-)NCBI
Rnor_5.0190,620,335 - 90,629,734 (-)NCBI
Celera180,636,897 - 80,646,025 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021909   ⟹   NP_068709
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,395,330 - 95,404,722 (-)NCBI
mRatBN7.2186,267,937 - 86,277,329 (-)NCBI
Rnor_6.0189,464,860 - 89,474,252 (-)NCBI
Rnor_5.0190,620,335 - 90,629,734 (-)NCBI
RGSC_v3.4186,076,279 - 86,085,681 (-)RGD
Celera180,636,897 - 80,646,373 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063272422   ⟹   XP_063128492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,395,327 - 95,404,657 (-)NCBI
RefSeq Acc Id: NP_068709   ⟸   NM_021909
- Peptide Label: precursor
- UniProtKB: Q6P9W0 (UniProtKB/Swiss-Prot),   P59647 (UniProtKB/Swiss-Prot),   A6JA47 (UniProtKB/TrEMBL),   A0A8I6A4C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257617   ⟸   NM_001270688
- Peptide Label: precursor
- UniProtKB: Q6P9W0 (UniProtKB/Swiss-Prot),   P59647 (UniProtKB/Swiss-Prot),   A6JA47 (UniProtKB/TrEMBL),   A0A8I6A4C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257618   ⟸   NM_001270689
- Peptide Label: precursor
- UniProtKB: Q6P9W0 (UniProtKB/Swiss-Prot),   P59647 (UniProtKB/Swiss-Prot),   A6JA47 (UniProtKB/TrEMBL),   A0A8I6A4C9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028597   ⟸   ENSRNOT00000028597
Ensembl Acc Id: ENSRNOP00000068919   ⟸   ENSRNOT00000089474
Ensembl Acc Id: ENSRNOP00000085788   ⟸   ENSRNOT00000117579
RefSeq Acc Id: XP_063128492   ⟸   XM_063272422
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R1T4 (UniProtKB/TrEMBL),   A0A8I6A4C9 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P59647-F1-model_v2 AlphaFold P59647 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689939
Promoter ID:EPDNEW_R464
Type:multiple initiation site
Name:Fxyd5_1
Description:FXYD domain-containing ion transport regulator 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R465  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,473,904 - 89,473,964EPDNEW
RGD ID:13689940
Promoter ID:EPDNEW_R465
Type:initiation region
Name:Fxyd5_2
Description:FXYD domain-containing ion transport regulator 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R464  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,474,235 - 89,474,295EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620827 AgrOrtholog
BioCyc Gene G2FUF-60051 BioCyc
Ensembl Genes ENSRNOG00000021062 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000089474 ENTREZGENE
Gene3D-CATH Single helix bin UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6891214 IMAGE-MGC_LOAD
InterPro FXYD_motif UniProtKB/Swiss-Prot
  Ion-transport_regulator_FXYD UniProtKB/Swiss-Prot
KEGG Report rno:60338 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72838 IMAGE-MGC_LOAD
NCBI Gene 60338 ENTREZGENE
PANTHER FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 5 UniProtKB/Swiss-Prot
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/Swiss-Prot
Pfam ATP1G1_PLM_MAT8 UniProtKB/Swiss-Prot
PhenoGen Fxyd5 PhenoGen
PROSITE FXYD UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021062 RatGTEx
UniProt A0A8I6A4C9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R1T4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UKH8_RAT UniProtKB/TrEMBL
  A6JA46_RAT UniProtKB/TrEMBL
  A6JA47 ENTREZGENE, UniProtKB/TrEMBL
  FXYD5_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P9W0 ENTREZGENE
UniProt Secondary Q6P9W0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-12-14 Fxyd5  FXYD domain-containing ion transport regulator 5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Fxyd5  FXYD domain-containing ion transport regulator 5      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function function as ion channels by assembling into multi-subunit complexes 632671
gene_product member of FXYD family of proteins has a 35 amino acid signature sequence 632671