Dcbld2 (discoidin, CUB and LCCL domain containing 2) - Rat Genome Database

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Gene: Dcbld2 (discoidin, CUB and LCCL domain containing 2) Rattus norvegicus
Analyze
Symbol: Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
RGD ID: 620543
Description: Predicted to enable signaling receptor activity. Predicted to be involved in negative regulation of cell growth and wound healing. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human DCBLD2 (discoidin, CUB and LCCL domain containing 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: discoidin, CUB and LCCL domain-containing protein 2; endothelial and smooth muscle cell-derived neuropilin-like protein; Esdn
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81155,594,691 - 55,649,113 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1155,594,691 - 55,649,085 (-)EnsemblGRCr8
mRatBN7.21142,125,525 - 42,179,927 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1142,125,787 - 42,179,697 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1150,873,338 - 50,927,850 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01143,534,906 - 43,589,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,663,530 - 42,718,044 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,237,814 - 44,292,884 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,241,111 - 44,292,884 (-)Ensemblrn6Rnor6.0
Rnor_5.01147,430,604 - 47,483,837 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41142,941,795 - 42,980,245 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1141,924,498 - 41,978,886 (-)NCBICelera
RGSC_v3.11142,999,383 - 43,037,833 (-)NCBI
Cytogenetic Map11q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
graphite  (EXP)
isobutanol  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methylparaben  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
PD 0325901  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
pyrogallol  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (ISO,ISS)
membrane  (IEA)
plasma membrane  (IBA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury. Kobuke K, etal., J Biol Chem 2001 Sep 7;276(36):34105-14.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Dcbld2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81155,594,691 - 55,649,113 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1155,594,691 - 55,649,085 (-)EnsemblGRCr8
mRatBN7.21142,125,525 - 42,179,927 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1142,125,787 - 42,179,697 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1150,873,338 - 50,927,850 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01143,534,906 - 43,589,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01142,663,530 - 42,718,044 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,237,814 - 44,292,884 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,241,111 - 44,292,884 (-)Ensemblrn6Rnor6.0
Rnor_5.01147,430,604 - 47,483,837 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41142,941,795 - 42,980,245 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1141,924,498 - 41,978,886 (-)NCBICelera
RGSC_v3.11142,999,383 - 43,037,833 (-)NCBI
Cytogenetic Map11q12NCBI
DCBLD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38398,795,941 - 98,901,695 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl398,795,941 - 98,901,729 (-)Ensemblhg38GRCh38
GRCh37398,514,785 - 98,620,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36399,997,504 - 100,103,223 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34399,997,503 - 100,103,223NCBI
Celera396,906,479 - 97,012,297 (-)NCBICelera
Cytogenetic Map3q12.1NCBI
HuRef395,886,827 - 95,992,670 (-)NCBIHuRef
CHM1_1398,477,944 - 98,585,228 (-)NCBICHM1_1
T2T-CHM13v2.03101,504,222 - 101,610,006 (-)NCBIT2T-CHM13v2.0
Dcbld2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391658,228,789 - 58,304,013 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1658,228,806 - 58,290,090 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381658,408,535 - 58,469,745 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1658,408,443 - 58,469,727 (+)Ensemblmm10GRCm38
MGSCv371658,408,648 - 58,469,858 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361658,351,078 - 58,412,288 (+)NCBIMGSCv36mm8
Celera1658,693,476 - 58,754,355 (+)NCBICelera
Cytogenetic Map16C1.2NCBI
cM Map1634.52NCBI
Dcbld2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955427453,820 - 553,859 (-)Ensembl
ChiLan1.0NW_004955427453,820 - 536,720 (-)NCBIChiLan1.0ChiLan1.0
DCBLD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2296,747,727 - 96,848,361 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1396,752,532 - 96,853,136 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0395,899,779 - 95,999,582 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13102,580,309 - 102,680,805 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3102,580,315 - 102,680,805 (-)EnsemblpanPan2panpan1.1
DCBLD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1335,627,315 - 5,691,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl335,628,578 - 5,691,680 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha335,778,219 - 5,858,365 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0335,766,275 - 5,846,552 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl335,766,293 - 5,847,129 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1335,651,967 - 5,732,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0335,702,254 - 5,782,714 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0335,978,829 - 6,065,249 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dcbld2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602151,243,087 - 151,326,852 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366304,140,933 - 4,226,078 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366304,140,999 - 4,224,741 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCBLD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13160,063,742 - 160,160,284 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113160,063,742 - 160,160,054 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213170,350,090 - 170,362,313 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCBLD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12281,974,031 - 82,065,697 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2281,974,141 - 82,062,160 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604184,489,190 - 84,580,627 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcbld2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478911,845,563 - 11,967,531 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dcbld2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1442,400,402 - 42,459,228 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dcbld2
235 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:28
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000002251
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
11528648Bss118Bone structure and strength QTL 1186.6582e-07femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)115410798756845449Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH140710  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21142,125,641 - 42,125,820 (+)MAPPERmRatBN7.2
Rnor_6.01144,240,966 - 44,241,144NCBIRnor6.0
Rnor_5.01147,430,459 - 47,430,637UniSTSRnor5.0
RGSC_v3.41142,941,650 - 42,941,828UniSTSRGSC3.4
Celera1141,924,353 - 41,924,531UniSTS
RH 3.4 Map11311.8UniSTS
Cytogenetic Map11q12UniSTS
RH66607  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81155,607,442 - 55,608,311 (+)Marker Load Pipeline
mRatBN7.21142,138,276 - 42,139,144 (+)MAPPERmRatBN7.2
Rnor_6.01144,253,580 - 44,254,450NCBIRnor6.0
Rnor_5.01147,443,172 - 47,444,042UniSTSRnor5.0
RGSC_v3.41142,954,366 - 42,955,233UniSTSRGSC3.4
Celera1141,937,224 - 41,938,091UniSTS
Cytogenetic Map11q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 78 59 6 341 178 11 139 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000084060   ⟹   ENSRNOP00000069998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1155,594,691 - 55,649,085 (-)Ensembl
mRatBN7.2 Ensembl1142,125,787 - 42,179,697 (-)Ensembl
Rnor_6.0 Ensembl1144,241,111 - 44,292,884 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110283   ⟹   ENSRNOP00000077062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1155,594,691 - 55,649,085 (-)Ensembl
mRatBN7.2 Ensembl1142,125,787 - 42,179,697 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000142908   ⟹   ENSRNOP00000112033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1155,594,691 - 55,649,085 (-)Ensembl
RefSeq Acc Id: NM_130419   ⟹   NP_569103
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81155,594,691 - 55,649,085 (-)NCBI
mRatBN7.21142,125,525 - 42,179,923 (-)NCBI
Rnor_6.01144,241,111 - 44,292,884 (-)NCBI
Rnor_5.01147,430,604 - 47,483,837 (-)NCBI
RGSC_v3.41142,941,795 - 42,980,245 (-)RGD
Celera1141,924,498 - 41,978,886 (-)RGD
Sequence:
RefSeq Acc Id: XM_039087921   ⟹   XP_038943849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81155,602,654 - 55,649,113 (-)NCBI
mRatBN7.21142,133,599 - 42,179,927 (-)NCBI
Protein Sequences
Protein RefSeqs NP_569103 (Get FASTA)   NCBI Sequence Viewer  
  XP_038943849 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL30180 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069998
GenBank Protein Q91ZV2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_569103   ⟸   NM_130419
- Peptide Label: precursor
- UniProtKB: Q91ZV2 (UniProtKB/Swiss-Prot),   A0A0G2JWS6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069998   ⟸   ENSRNOT00000084060
RefSeq Acc Id: XP_038943849   ⟸   XM_039087921
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000077062   ⟸   ENSRNOT00000110283
Ensembl Acc Id: ENSRNOP00000112033   ⟸   ENSRNOT00000142908
Protein Domains
CUB   F5/8 type C   LCCL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91ZV2-F1-model_v2 AlphaFold Q91ZV2 1-769 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620543 AgrOrtholog
BioCyc Gene G2FUF-21560 BioCyc
Ensembl Genes ENSRNOG00000055281 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000084060 ENTREZGENE
Gene3D-CATH 2.170.130.20 UniProtKB/Swiss-Prot
  2.60.120.290 UniProtKB/Swiss-Prot
  Galactose-binding domain-like UniProtKB/Swiss-Prot
InterPro CUB_dom UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  LCCL UniProtKB/Swiss-Prot
  LCCL_sf UniProtKB/Swiss-Prot
  Neuropilin_MCO_CoagFactor UniProtKB/Swiss-Prot
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:155696 UniProtKB/Swiss-Prot
NCBI Gene 155696 ENTREZGENE
PANTHER DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
  F5/8 TYPE C DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam CUB UniProtKB/Swiss-Prot
  F5_F8_type_C UniProtKB/Swiss-Prot
  LCCL UniProtKB/Swiss-Prot
PhenoGen Dcbld2 PhenoGen
PROSITE CUB UniProtKB/Swiss-Prot
  FA58C_1 UniProtKB/Swiss-Prot
  FA58C_3 UniProtKB/Swiss-Prot
  LCCL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000055281 RatGTEx
SMART CUB UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  LCCL UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49785 UniProtKB/Swiss-Prot
  SSF49854 UniProtKB/Swiss-Prot
  SSF69848 UniProtKB/Swiss-Prot
UniProt A0A0G2JWS6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y7D9_RAT UniProtKB/TrEMBL
  A0ABK0M7S5_RAT UniProtKB/TrEMBL
  DCBD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Dcbld2  discoidin, CUB and LCCL domain containing 2  Esdn  endothelial and smooth muscle cell-derived neuropilin-like protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Esdn  endothelial and smooth muscle cell-derived neuropilin-like protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a CUB domain, a coagulation factor V/VIII homology domain and an LCCL domain 632753
gene_homology 84% amino acid identity with human homolog 632753