Stk17b (serine/threonine kinase 17b) - Rat Genome Database

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Gene: Stk17b (serine/threonine kinase 17b) Rattus norvegicus
Analyze
Symbol: Stk17b
Name: serine/threonine kinase 17b
RGD ID: 620457
Description: Enables ATP binding activity and protein serine/threonine kinase activity. Involved in apoptotic process; intracellular signal transduction; and protein autophosphorylation. Located in actin cytoskeleton and nucleus. Orthologous to human STK17B (serine/threonine kinase 17b); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2; Drak2; serine/threonine kinase 17b (apoptosis-inducing); serine/threonine-protein kinase 17B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8962,801,912 - 62,832,511 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl962,803,005 - 62,832,511 (-)EnsemblGRCr8
mRatBN7.2955,307,485 - 55,338,085 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,307,668 - 55,338,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx963,816,526 - 63,846,044 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0968,932,306 - 68,961,824 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0967,228,148 - 67,257,666 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0960,399,261 - 60,430,081 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl960,399,261 - 60,430,081 (-)Ensemblrn6Rnor6.0
Rnor_5.0960,084,854 - 60,115,674 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4952,567,310 - 52,596,817 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera952,803,380 - 52,832,885 (-)NCBICelera
RGSC_v3.1952,568,723 - 52,598,231 (-)NCBI
Cytogenetic Map9q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-ethoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
depsipeptide  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dieldrin  (EXP)
doxorubicin  (ISO)
fenamidone  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (EXP)
gentamycin  (EXP)
iloprost  (ISO)
indometacin  (ISO)
inulin  (ISO)
L-ascorbic acid  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
naled  (ISO)
nickel atom  (ISO)
Nonylphenol  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP. Kuwahara H, etal., J Biochem. 2003 Aug;134(2):245-50.
4. A serine/threonine kinase which causes apoptosis-like cell death interacts with a calcineurin B-like protein capable of binding Na(+)/H(+) exchanger. Matsumoto M, etal., J Biochem (Tokyo) 2001 Aug;130(2):217-25.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. CFU-C in Agar. Praloran V and Bartocci A, Methods Mol Biol. 1990;5:323-30. doi: 10.1385/0-89603-150-0:323.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9786912   PMID:18084041  


Genomics

Comparative Map Data
Stk17b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8962,801,912 - 62,832,511 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl962,803,005 - 62,832,511 (-)EnsemblGRCr8
mRatBN7.2955,307,485 - 55,338,085 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,307,668 - 55,338,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx963,816,526 - 63,846,044 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0968,932,306 - 68,961,824 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0967,228,148 - 67,257,666 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0960,399,261 - 60,430,081 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl960,399,261 - 60,430,081 (-)Ensemblrn6Rnor6.0
Rnor_5.0960,084,854 - 60,115,674 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4952,567,310 - 52,596,817 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera952,803,380 - 52,832,885 (-)NCBICelera
RGSC_v3.1952,568,723 - 52,598,231 (-)NCBI
Cytogenetic Map9q31NCBI
STK17B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382196,133,583 - 196,176,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2196,133,583 - 196,176,503 (-)Ensemblhg38GRCh38
GRCh372196,998,307 - 197,036,302 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362196,710,102 - 196,744,520 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342196,827,364 - 196,861,781NCBI
Celera2190,754,094 - 190,792,103 (-)NCBICelera
Cytogenetic Map2q32.3NCBI
HuRef2188,851,130 - 188,889,152 (-)NCBIHuRef
CHM1_12197,004,189 - 197,042,201 (-)NCBICHM1_1
T2T-CHM13v2.02196,617,655 - 196,666,801 (-)NCBIT2T-CHM13v2.0
Stk17b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,794,671 - 53,824,374 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,794,665 - 53,824,383 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38153,755,512 - 53,785,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,755,506 - 53,785,224 (-)Ensemblmm10GRCm38
MGSCv37153,812,356 - 53,842,059 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36153,700,057 - 53,729,697 (-)NCBIMGSCv36mm8
Celera154,295,821 - 54,325,524 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.99NCBI
Stk17b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554034,115,766 - 4,145,698 (+)Ensembl
ChiLan1.0NW_0049554034,116,130 - 4,145,698 (+)NCBIChiLan1.0ChiLan1.0
STK17B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21398,760,466 - 98,802,611 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B98,775,320 - 98,817,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B83,384,562 - 83,422,642 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B201,285,119 - 201,323,314 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B201,285,119 - 201,323,314 (-)EnsemblpanPan2panpan1.1
STK17B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1375,801,482 - 5,822,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl375,801,938 - 5,819,903 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha376,747,886 - 6,776,684 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0375,687,153 - 5,715,988 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl375,689,562 - 5,708,010 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1375,687,773 - 5,716,640 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0375,655,102 - 5,683,802 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0375,676,401 - 5,705,213 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stk17b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303153,874,501 - 153,903,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365062,934,173 - 2,966,614 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365062,934,130 - 2,963,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK17B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15100,029,994 - 100,066,238 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115100,029,987 - 100,066,297 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215111,026,262 - 111,052,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STK17B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11081,674,258 - 81,712,148 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1081,674,199 - 81,712,123 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040117,733,618 - 117,771,145 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stk17b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624854853,005 - 879,316 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624854847,030 - 878,617 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Stk17b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14128,473,875 - 128,504,585 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Stk17b
155 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:96
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000016856
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
UniSTS:498358  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2955,308,204 - 55,308,349 (+)MAPPERmRatBN7.2
Rnor_6.0960,399,981 - 60,400,125NCBIRnor6.0
Rnor_5.0960,085,574 - 60,085,718UniSTSRnor5.0
RGSC_v3.4952,566,937 - 52,567,081UniSTSRGSC3.4
Celera952,803,007 - 52,803,151UniSTS
Cytogenetic Map9q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000016856   ⟹   ENSRNOP00000016857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl962,803,005 - 62,832,511 (-)Ensembl
mRatBN7.2 Ensembl955,307,668 - 55,338,031 (-)Ensembl
Rnor_6.0 Ensembl960,399,261 - 60,430,081 (-)Ensembl
RefSeq Acc Id: NM_133392   ⟹   NP_596883
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8962,803,005 - 62,832,511 (-)NCBI
mRatBN7.2955,308,578 - 55,338,085 (-)NCBI
Rnor_6.0960,400,354 - 60,430,081 (-)NCBI
Rnor_5.0960,084,854 - 60,115,674 (-)NCBI
RGSC_v3.4952,567,310 - 52,596,817 (-)RGD
Celera952,803,380 - 52,832,885 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244908   ⟹   XP_006244970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8962,801,912 - 62,832,509 (-)NCBI
mRatBN7.2955,307,485 - 55,337,330 (-)NCBI
Rnor_6.0960,399,261 - 60,429,951 (-)NCBI
Rnor_5.0960,084,854 - 60,115,674 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039082990   ⟹   XP_038938918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8962,801,912 - 62,832,492 (-)NCBI
mRatBN7.2955,307,485 - 55,337,404 (-)NCBI
RefSeq Acc Id: XM_039082991   ⟹   XP_038938919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8962,801,912 - 62,820,955 (-)NCBI
mRatBN7.2955,307,485 - 55,326,526 (-)NCBI
RefSeq Acc Id: NP_596883   ⟸   NM_133392
- UniProtKB: Q91XS8 (UniProtKB/Swiss-Prot),   A6INZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244970   ⟸   XM_006244908
- Peptide Label: isoform X1
- UniProtKB: Q91XS8 (UniProtKB/Swiss-Prot),   A6INZ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016857   ⟸   ENSRNOT00000016856
RefSeq Acc Id: XP_038938918   ⟸   XM_039082990
- Peptide Label: isoform X1
- UniProtKB: Q91XS8 (UniProtKB/Swiss-Prot),   A6INZ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938919   ⟸   XM_039082991
- Peptide Label: isoform X2
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91XS8-F1-model_v2 AlphaFold Q91XS8 1-371 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696664
Promoter ID:EPDNEW_R7188
Type:multiple initiation site
Name:Stk17b_1
Description:serine/threonine kinase 17b
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0960,430,065 - 60,430,125EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620457 AgrOrtholog
BioCyc Gene G2FUF-27554 BioCyc
Ensembl Genes ENSRNOG00000012502 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016856 ENTREZGENE
  ENSRNOT00000016856.5 UniProtKB/Swiss-Prot
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom UniProtKB/Swiss-Prot
  Prot_kinase_cat_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_prot_kinase_AS UniProtKB/Swiss-Prot
  ST17B_STKc UniProtKB/Swiss-Prot
KEGG Report rno:170904 UniProtKB/Swiss-Prot
NCBI Gene 170904 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE 17 UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE 17B UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Stk17b PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012502 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP Kinase_like UniProtKB/Swiss-Prot
UniProt A6INZ2 ENTREZGENE, UniProtKB/TrEMBL
  Q91XS8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Stk17b  serine/threonine kinase 17b  Stk17b  serine/threonine kinase 17b (apoptosis-inducing)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Stk17b  serine/threonine kinase 17b (apoptosis-inducing)      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Stk17b  serine/threonine kinase 17b (apoptosis-inducing)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the nucleus 634154
gene_physical_interaction bind in vitro with calcineurin homologous protein (CHP) 634154