Ppp1r1a (protein phosphatase 1, regulatory (inhibitor) subunit 1A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ppp1r1a (protein phosphatase 1, regulatory (inhibitor) subunit 1A) Rattus norvegicus
Analyze
Symbol: Ppp1r1a
Name: protein phosphatase 1, regulatory (inhibitor) subunit 1A
RGD ID: 62018
Description: Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Located in extracellular space. Orthologous to human PPP1R1A (protein phosphatase 1 regulatory inhibitor subunit 1A); PARTICIPATES IN long term potentiation; INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: I-1; IPP-1; PP1 inhibitor 1; protein phosphatase 1 regulatory subunit 1A; protein phosphatase inhibitor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,533,031 - 136,540,687 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7136,523,604 - 136,540,683 (-)EnsemblGRCr8
mRatBN7.27134,654,578 - 134,662,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,654,579 - 134,662,230 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7136,410,417 - 136,418,114 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,639,788 - 138,647,485 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,625,389 - 138,633,131 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd7138,608,428 - 138,616,081 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive7139,560,742 - 139,568,395 (-)NCBILyon_Normotensive
Lyon_Hypertensive7139,692,928 - 139,700,567 (-)NCBILyon_Hypertensive
F344_StmMcwi7138,155,130 - 138,162,827 (-)NCBIF344_StmMcwi
Rnor_6.07145,146,480 - 145,154,131 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)Ensemblrn6Rnor6.0
Rnor_5.07142,925,730 - 142,933,709 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47142,428,730 - 142,436,381 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7131,078,656 - 131,086,307 (-)NCBICelera
RGSC_v3.17142,508,919 - 142,516,570 (-)NCBI
Cytogenetic Map7q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
chenodeoxycholic acid  (ISO)
chlordecone  (ISO)
ciguatoxin CTX1B  (ISO)
clozapine  (EXP)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
haloperidol  (EXP)
indometacin  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
terbufos  (ISO)
testosterone  (EXP,ISO)
thalidomide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zearalenone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Detection and quantification of protein phosphatase inhibitor-1 gene expression in total rat liver and isolated hepatocytes. Aleem EA, etal., Mol Cell Biochem 2001 Jan;217(1-2):1-12.
2. Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues. Elbrecht A, etal., J Biol Chem 1990 Aug 15;265(23):13415-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Potential of Protein Phosphatase Inhibitor 1 As Biomarker of Pancreatic beta-Cell Injury In Vitro and In Vivo. Jiang L, etal., Diabetes. 2013 Aug;62(8):2683-8. doi: 10.2337/db12-1507. Epub 2013 Apr 4.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:16774736   PMID:19377265  


Genomics

Comparative Map Data
Ppp1r1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87136,533,031 - 136,540,687 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7136,523,604 - 136,540,683 (-)EnsemblGRCr8
mRatBN7.27134,654,578 - 134,662,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,654,579 - 134,662,230 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7136,410,417 - 136,418,114 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07138,639,788 - 138,647,485 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07138,625,389 - 138,633,131 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd7138,608,428 - 138,616,081 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive7139,560,742 - 139,568,395 (-)NCBILyon_Normotensive
Lyon_Hypertensive7139,692,928 - 139,700,567 (-)NCBILyon_Hypertensive
F344_StmMcwi7138,155,130 - 138,162,827 (-)NCBIF344_StmMcwi
Rnor_6.07145,146,480 - 145,154,131 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)Ensemblrn6Rnor6.0
Rnor_5.07142,925,730 - 142,933,709 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47142,428,730 - 142,436,381 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7131,078,656 - 131,086,307 (-)NCBICelera
RGSC_v3.17142,508,919 - 142,516,570 (-)NCBI
Cytogenetic Map7q36NCBI
PPP1R1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381254,579,246 - 54,588,659 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1254,575,387 - 54,588,659 (-)Ensemblhg38GRCh38
GRCh371254,973,030 - 54,982,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,259,291 - 53,268,710 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341253,259,299 - 53,268,707NCBI
Celera1254,624,894 - 54,634,311 (-)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1252,011,832 - 52,016,913 (-)NCBIHuRef
CHM1_11254,939,731 - 54,949,148 (-)NCBICHM1_1
T2T-CHM13v2.01254,545,797 - 54,555,209 (-)NCBIT2T-CHM13v2.0
Ppp1r1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,438,706 - 103,446,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15103,438,706 - 103,446,430 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3815103,530,279 - 103,538,027 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,530,279 - 103,538,003 (-)Ensemblmm10GRCm38
MGSCv3715103,360,710 - 103,368,423 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3615103,358,313 - 103,365,995 (-)NCBIMGSCv36mm8
Celera15105,688,277 - 105,695,984 (-)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1559.01NCBI
Ppp1r1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,819,366 - 1,823,867 (-)Ensembl
ChiLan1.0NW_0049554581,819,366 - 1,823,864 (-)NCBIChiLan1.0ChiLan1.0
PPP1R1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21039,586,156 - 39,594,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11239,582,925 - 39,591,321 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01234,158,956 - 34,167,350 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11234,887,168 - 34,896,360 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1234,882,975 - 34,898,218 (+)EnsemblpanPan2panpan1.1
PPP1R1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127766,757 - 770,994 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl27766,338 - 771,598 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2745,482,576 - 45,490,666 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.027761,676 - 770,078 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl27761,653 - 770,038 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.127754,299 - 762,405 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.027762,376 - 770,488 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02745,886,785 - 45,894,624 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp1r1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,389,455 - 61,397,676 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651211,767,172 - 11,775,573 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651211,765,769 - 11,775,573 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,753,847 - 19,763,269 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1519,753,850 - 19,763,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PPP1R1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,695,896 - 50,704,191 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1150,696,032 - 50,704,219 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037195,332,472 - 195,341,778 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249042,608,895 - 2,617,543 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249042,608,891 - 2,617,202 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp1r1a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11259,550,795 - 259,558,151 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:102
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000055271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)7132099939137014596Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7135371291137014596Rat

Markers in Region
RH127463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,654,201 - 134,654,408 (+)MAPPERmRatBN7.2
Rnor_6.07145,146,104 - 145,146,310NCBIRnor6.0
Rnor_5.07142,925,354 - 142,925,560UniSTSRnor5.0
RGSC_v3.47142,428,354 - 142,428,560UniSTSRGSC3.4
Celera7131,078,280 - 131,078,486UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS
RH130620  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27134,654,856 - 134,655,051 (+)MAPPERmRatBN7.2
Rnor_6.07145,146,759 - 145,146,953NCBIRnor6.0
Rnor_5.07142,926,009 - 142,926,203UniSTSRnor5.0
RGSC_v3.47142,429,009 - 142,429,203UniSTSRGSC3.4
Celera7131,078,935 - 131,079,129UniSTS
RH 3.4 Map71063.5UniSTS
Cytogenetic Map7q36UniSTS
AA997855  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr87136,533,875 - 136,534,432 (+)Marker Load Pipeline
mRatBN7.27134,655,422 - 134,655,979 (+)MAPPERmRatBN7.2
Rnor_6.07145,147,325 - 145,147,881NCBIRnor6.0
Rnor_5.07142,926,575 - 142,927,131UniSTSRnor5.0
RGSC_v3.47142,429,575 - 142,430,131UniSTSRGSC3.4
Celera7131,079,501 - 131,080,057UniSTS
RH 3.4 Map71064.9UniSTS
Cytogenetic Map7q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 83 82 51 50 51 6 306 150 11 133 81 87 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000055271   ⟹   ENSRNOP00000052146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,533,032 - 136,540,682 (-)Ensembl
mRatBN7.2 Ensembl7134,654,579 - 134,662,229 (-)Ensembl
Rnor_6.0 Ensembl7145,146,481 - 145,154,131 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105860   ⟹   ENSRNOP00000079380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,523,604 - 136,540,683 (-)Ensembl
mRatBN7.2 Ensembl7134,655,776 - 134,662,230 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000127604   ⟹   ENSRNOP00000106298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7136,533,228 - 136,540,683 (-)Ensembl
RefSeq Acc Id: NM_022676   ⟹   NP_073167
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,533,031 - 136,540,682 (-)NCBI
mRatBN7.27134,654,578 - 134,662,229 (-)NCBI
Dahl_SR_JrHsd7138,608,428 - 138,616,081 (-)NCBI
Lyon_Normotensive7139,560,742 - 139,568,395 (-)NCBI
Lyon_Hypertensive7139,692,928 - 139,700,567 (-)NCBI
F344_StmMcwi7138,155,130 - 138,162,827 (-)NCBI
Rnor_6.07145,146,480 - 145,154,131 (-)NCBI
Rnor_5.07142,925,730 - 142,933,709 (-)NCBI
RGSC_v3.47142,428,730 - 142,436,381 (-)RGD
Celera7131,078,656 - 131,086,307 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242437   ⟹   XP_006242499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87136,533,829 - 136,540,687 (-)NCBI
mRatBN7.27134,654,813 - 134,662,236 (-)NCBI
Rnor_6.07145,147,278 - 145,154,105 (-)NCBI
Rnor_5.07142,925,730 - 142,933,709 (-)NCBI
Sequence:
RefSeq Acc Id: NP_073167   ⟸   NM_022676
- UniProtKB: Q6DSU5 (UniProtKB/Swiss-Prot),   P19103 (UniProtKB/Swiss-Prot),   A6KD17 (UniProtKB/TrEMBL),   A6KD15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242499   ⟸   XM_006242437
- Peptide Label: isoform X1
- UniProtKB: A6KD15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052146   ⟸   ENSRNOT00000055271
Ensembl Acc Id: ENSRNOP00000079380   ⟸   ENSRNOT00000105860
Ensembl Acc Id: ENSRNOP00000106298   ⟸   ENSRNOT00000127604

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19103-F1-model_v2 AlphaFold P19103 1-171 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695720
Promoter ID:EPDNEW_R6245
Type:initiation region
Name:Ppp1r1a_1
Description:protein phosphatase 1, regulatory subunit 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07145,154,131 - 145,154,191EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62018 AgrOrtholog
BioCyc Gene G2FUF-31867 BioCyc
Ensembl Genes ENSRNOG00000036827 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055271 ENTREZGENE
  ENSRNOT00000055271.3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127505 IMAGE-MGC_LOAD
InterPro PPP1R1A/B/C UniProtKB/Swiss-Prot
KEGG Report rno:58977 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93431 IMAGE-MGC_LOAD
NCBI Gene 58977 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1A UniProtKB/Swiss-Prot
  PTHR15417 UniProtKB/Swiss-Prot
Pfam DARPP-32 UniProtKB/Swiss-Prot
PhenoGen Ppp1r1a PhenoGen
RatGTEx ENSRNOG00000036827 RatGTEx
UniProt A0A8I6G585_RAT UniProtKB/TrEMBL
  A0ABK0LZ99_RAT UniProtKB/TrEMBL
  A6KD14_RAT UniProtKB/TrEMBL
  A6KD15 ENTREZGENE, UniProtKB/TrEMBL
  A6KD16_RAT UniProtKB/TrEMBL
  A6KD17 ENTREZGENE, UniProtKB/TrEMBL
  P19103 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6DSU5 ENTREZGENE
UniProt Secondary Q6DSU5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ppp1r1a  protein phosphatase 1, regulatory (inhibitor) subunit 1A       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation may be threonine phosphorylated by cAMP-dependent protein kinase 61702