Wbp4 (WW domain binding protein 4) - Rat Genome Database

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Gene: Wbp4 (WW domain binding protein 4) Rattus norvegicus
Analyze
Symbol: Wbp4
Name: WW domain binding protein 4
RGD ID: 620033
Description: Predicted to enable RNA binding activity and proline-rich region binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of U2-type precatalytic spliceosome. Orthologous to human WBP4 (WW domain binding protein 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fbp21; formin-binding protein 21; WBP-4; WW domain binding protein 4 (formin binding protein 21); WW domain-binding protein 4; WW domain-containing-binding protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,271,774 - 61,299,740 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1561,271,783 - 61,299,740 (-)EnsemblGRCr8
mRatBN7.21554,862,700 - 54,890,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,862,843 - 54,890,647 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1558,996,202 - 59,024,140 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,114,592 - 60,142,530 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01556,939,474 - 56,967,410 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01561,745,989 - 61,772,516 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,745,989 - 61,772,516 (-)Ensemblrn6Rnor6.0
Rnor_5.01565,410,539 - 65,436,878 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41561,517,401 - 61,543,453 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1554,446,104 - 54,472,025 (-)NCBICelera
RGSC_v3.11561,545,941 - 61,551,137 (-)NCBI
Cytogenetic Map15q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear speck  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO,ISS)
precatalytic spliceosome  (IBA)
spliceosomal complex  (IEA,ISO)
U2-type precatalytic spliceosome  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2. WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif. Bedford MT, etal., Proc Natl Acad Sci U S A 1998 Sep 1;95(18):10602-7.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:19592703   PMID:28781166  


Genomics

Comparative Map Data
Wbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,271,774 - 61,299,740 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1561,271,783 - 61,299,740 (-)EnsemblGRCr8
mRatBN7.21554,862,700 - 54,890,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,862,843 - 54,890,647 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1558,996,202 - 59,024,140 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,114,592 - 60,142,530 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01556,939,474 - 56,967,410 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01561,745,989 - 61,772,516 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,745,989 - 61,772,516 (-)Ensemblrn6Rnor6.0
Rnor_5.01565,410,539 - 65,436,878 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41561,517,401 - 61,543,453 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1554,446,104 - 54,472,025 (-)NCBICelera
RGSC_v3.11561,545,941 - 61,551,137 (-)NCBI
Cytogenetic Map15q12NCBI
WBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381341,061,509 - 41,084,006 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1341,061,509 - 41,084,006 (+)Ensemblhg38GRCh38
GRCh371341,635,645 - 41,658,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361340,533,697 - 40,556,139 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341340,533,696 - 40,556,137NCBI
Celera1322,693,135 - 22,715,573 (+)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1322,436,344 - 22,458,782 (+)NCBIHuRef
CHM1_11341,603,556 - 41,625,992 (+)NCBICHM1_1
T2T-CHM13v2.01340,280,657 - 40,303,155 (+)NCBIT2T-CHM13v2.0
Wbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391479,697,377 - 79,718,708 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1479,697,377 - 79,718,960 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381479,459,937 - 79,481,268 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1479,459,937 - 79,481,520 (-)Ensemblmm10GRCm38
MGSCv371479,859,744 - 79,881,075 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361478,194,092 - 78,215,423 (-)NCBIMGSCv36mm8
Celera1476,959,934 - 76,981,390 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1442.66NCBI
Wbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540451,046,177 - 51,084,272 (+)Ensembl
ChiLan1.0NW_00495540451,046,245 - 51,094,245 (+)NCBIChiLan1.0ChiLan1.0
WBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21440,578,539 - 40,600,218 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11331,681,568 - 31,704,726 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01322,263,547 - 22,286,071 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11340,852,879 - 40,875,182 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1340,852,971 - 40,875,173 (+)EnsemblpanPan2panpan1.1
WBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,504,525 - 9,565,230 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,505,012 - 9,565,208 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha229,500,648 - 9,561,334 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0229,727,648 - 9,788,359 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,728,135 - 9,788,316 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1229,426,046 - 9,486,716 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,475,587 - 9,536,308 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,489,994 - 9,550,734 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,450,151 - 151,472,946 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936667423,883 - 450,214 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936667426,752 - 449,562 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1125,731,390 - 25,771,961 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11125,735,209 - 25,772,555 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
WBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,332,616 - 19,355,594 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,332,766 - 19,356,162 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605724,880,434 - 24,903,535 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474813,956,663 - 13,986,487 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474813,956,637 - 13,986,730 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Wbp4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11244,860,007 - 44,885,685 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Wbp4
211 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:86
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000015605
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155720389580107161Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
RH143576  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,877,277 - 54,877,390 (+)MAPPERmRatBN7.2
mRatBN7.23130,893,725 - 130,893,838 (+)MAPPERmRatBN7.2
Rnor_6.01561,759,128 - 61,759,240NCBIRnor6.0
Rnor_6.03137,632,193 - 137,632,305NCBIRnor6.0
Rnor_5.01565,423,167 - 65,423,279UniSTSRnor5.0
Rnor_5.03144,072,423 - 144,072,535UniSTSRnor5.0
RGSC_v3.43131,938,950 - 131,939,062UniSTSRGSC3.4
RGSC_v3.41561,530,065 - 61,530,177UniSTSRGSC3.4
Celera1554,458,637 - 54,458,749UniSTS
Celera3129,806,006 - 129,806,118UniSTS
RH 3.4 Map15459.9UniSTS
Cytogenetic Map15q12UniSTS
Cytogenetic Map3q42UniSTS
BE103347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,864,229 - 54,864,412 (+)MAPPERmRatBN7.2
mRatBN7.23130,893,185 - 130,893,323 (+)MAPPERmRatBN7.2
Rnor_6.01561,747,519 - 61,747,701NCBIRnor6.0
Rnor_5.01565,410,497 - 65,410,679UniSTSRnor5.0
RGSC_v3.41561,517,359 - 61,517,541UniSTSRGSC3.4
Celera1554,446,062 - 54,446,244UniSTS
RH 3.4 Map15458.4UniSTS
Cytogenetic Map15q12UniSTS
BE117645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23130,894,126 - 130,894,280 (+)MAPPERmRatBN7.2
Rnor_6.03137,632,594 - 137,632,747NCBIRnor6.0
Rnor_5.03144,072,824 - 144,072,977UniSTSRnor5.0
RGSC_v3.43131,939,351 - 131,939,504UniSTSRGSC3.4
Celera3129,806,407 - 129,806,560UniSTS
RH 3.4 Map31173.8UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map15q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015605   ⟹   ENSRNOP00000015605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1561,271,783 - 61,298,904 (-)Ensembl
mRatBN7.2 Ensembl1554,862,843 - 54,889,832 (-)Ensembl
Rnor_6.0 Ensembl1561,745,989 - 61,772,516 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1561,764,071 - 61,768,304 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1561,753,347 - 61,762,685 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093399   ⟹   ENSRNOP00000076128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1561,771,371 - 61,772,516 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093753   ⟹   ENSRNOP00000076158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1561,747,561 - 61,761,886 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102266   ⟹   ENSRNOP00000077691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1561,271,783 - 61,297,789 (-)Ensembl
mRatBN7.2 Ensembl1554,862,843 - 54,890,287 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111542   ⟹   ENSRNOP00000076733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1561,271,783 - 61,299,740 (-)Ensembl
mRatBN7.2 Ensembl1554,863,494 - 54,890,647 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132918   ⟹   ENSRNOP00000102685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1561,271,783 - 61,299,536 (-)Ensembl
RefSeq Acc Id: NM_053766   ⟹   NP_446218
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,271,783 - 61,299,740 (-)NCBI
mRatBN7.21554,862,709 - 54,890,668 (-)NCBI
Rnor_6.01561,747,561 - 61,772,516 (-)NCBI
Rnor_5.01565,410,539 - 65,436,878 (-)NCBI
RGSC_v3.41561,517,401 - 61,543,453 (-)RGD
Celera1554,446,104 - 54,472,025 (-)RGD
Sequence:
RefSeq Acc Id: XM_008770840   ⟹   XP_008769062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,271,774 - 61,297,844 (-)NCBI
mRatBN7.21554,862,700 - 54,889,574 (-)NCBI
Rnor_6.01561,745,989 - 61,771,343 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063273904   ⟹   XP_063129974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,286,308 - 61,299,222 (-)NCBI
RefSeq Acc Id: XM_063273905   ⟹   XP_063129975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,286,308 - 61,299,222 (-)NCBI
RefSeq Acc Id: XM_063273906   ⟹   XP_063129976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,286,308 - 61,299,305 (-)NCBI
RefSeq Acc Id: XM_063273907   ⟹   XP_063129977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,289,086 - 61,299,222 (-)NCBI
RefSeq Acc Id: XR_010057795
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81561,289,086 - 61,299,222 (-)NCBI
RefSeq Acc Id: NP_446218   ⟸   NM_053766
- UniProtKB: Q5HZF2 (UniProtKB/Swiss-Prot),   A6HTZ4 (UniProtKB/TrEMBL),   A0A8L2Q7K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769062   ⟸   XM_008770840
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y9P1 (UniProtKB/TrEMBL),   A0A8L2Q7K4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076158   ⟸   ENSRNOT00000093753
Ensembl Acc Id: ENSRNOP00000076128   ⟸   ENSRNOT00000093399
Ensembl Acc Id: ENSRNOP00000015605   ⟸   ENSRNOT00000015605
Ensembl Acc Id: ENSRNOP00000076733   ⟸   ENSRNOT00000111542
Ensembl Acc Id: ENSRNOP00000077691   ⟸   ENSRNOT00000102266
RefSeq Acc Id: XP_063129976   ⟸   XM_063273906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063129974   ⟸   XM_063273904
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063129975   ⟸   XM_063273905
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063129977   ⟸   XM_063273907
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000102685   ⟸   ENSRNOT00000132918
Protein Domains
Matrin-type   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5HZF2-F1-model_v2 AlphaFold Q5HZF2 1-374 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699848
Promoter ID:EPDNEW_R10372
Type:initiation region
Name:Wbp4_2
Description:WW domain binding protein 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10373  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01561,772,017 - 61,772,077EPDNEW
RGD ID:13699849
Promoter ID:EPDNEW_R10373
Type:initiation region
Name:Wbp4_1
Description:WW domain binding protein 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10372  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01561,772,479 - 61,772,539EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620033 AgrOrtholog
BioCyc Gene G2FUF-12991 BioCyc
Ensembl Genes ENSRNOG00000011678 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000102266 ENTREZGENE
  ENSRNOT00000111542 ENTREZGENE
  ENSRNOT00000111542.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.20.70.10 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7307299 IMAGE-MGC_LOAD
InterPro Matrin/U1-C_Znf_C2H2 UniProtKB/Swiss-Prot
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/Swiss-Prot
  U1-CZ_Znf_C2H2 UniProtKB/Swiss-Prot
  WBP4 UniProtKB/Swiss-Prot
  WW_dom UniProtKB/Swiss-Prot
  WW_dom_sf UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
KEGG Report rno:114765 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105552 IMAGE-MGC_LOAD
NCBI Gene 114765 ENTREZGENE
PANTHER PTHR13173 UniProtKB/Swiss-Prot
  WW DOMAIN-BINDING PROTEIN 4 UniProtKB/Swiss-Prot
Pfam PF00397 UniProtKB/Swiss-Prot
  zf-U1 UniProtKB/Swiss-Prot
PhenoGen Wbp4 PhenoGen
PROSITE WW_DOMAIN_1 UniProtKB/Swiss-Prot
  WW_DOMAIN_2 UniProtKB/Swiss-Prot
  ZF_MATRIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011678 RatGTEx
SMART SM00456 UniProtKB/Swiss-Prot
  ZnF_U1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51045 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot
UniProt A0A8I5Y9P1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q7K4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LIC6_RAT UniProtKB/TrEMBL
  A6HTZ4 ENTREZGENE, UniProtKB/TrEMBL
  A6HTZ5_RAT UniProtKB/TrEMBL
  Q5HZF2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-24 Wbp4  WW domain binding protein 4  Wbp4  WW domain binding protein 4 (formin binding protein 21)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Wbp4  WW domain binding protein 4 (formin binding protein 21)  Wbp4  WW domain binding protein 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Wbp4  WW domain binding protein 4    WW domain binding protein 4 (formin binding protein 21)  Name updated 1299863 APPROVED
2002-08-07 Wbp4  WW domain binding protein 4 (formin binding protein 21)      Symbol and Name status set to provisional 70820 PROVISIONAL