Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dnah12 | Rat | Spermatogenic Failure 100 | | ISO | DNAH12 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dnah12 | Rat | Spermatogenic Failure 100 | | ISO | DNAH12 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Identification of seven rat axonemal dynein heavy chain genes: expression during ciliated cell differentiation. | Andrews KL, etal., Mol Biol Cell 1996 Jan;7(1):71-9. |
| 2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| Dnah12 (Rattus norvegicus - Norway rat) |
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| DNAH12 (Homo sapiens - human) |
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| Dnah12 (Mus musculus - house mouse) |
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| Dnah12 (Chinchilla lanigera - long-tailed chinchilla) |
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| DNAH12 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DNAH12 (Canis lupus familiaris - dog) |
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| Dnah12 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DNAH12 (Sus scrofa - pig) |
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| DNAH12 (Chlorocebus sabaeus - green monkey) |
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| Dnah12 (Heterocephalus glaber - naked mole-rat) |
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| Dnah12 (Rattus rattus - black rat) |
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Variants in Dnah12
919 total Variants
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| D16Chm68 |
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| D16Chm73 |
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| D16Chm69 |
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| D16Chm48 |
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| D16Got124 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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| 16 | 7 | 29 | 155 | 57 | 57 | 26 | 60 | 26 | 6 | 242 | 112 | 9 | 136 | 81 | 90 | 31 | 9 | 9 |
| Ensembl Acc Id: | ENSRNOT00000079215 ⟹ ENSRNOP00000074159 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000097079 ⟹ ENSRNOP00000087078 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000150257 ⟹ ENSRNOP00000110882 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000154560 ⟹ ENSRNOP00000112549 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000160611 ⟹ ENSRNOP00000103541 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001419553 ⟹ NP_001406482 | ||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063275064 ⟹ XP_063131134 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063275065 ⟹ XP_063131135 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063275066 ⟹ XP_063131136 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063275067 ⟹ XP_063131137 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOP00000074159 ⟸ ENSRNOT00000079215 |
| Ensembl Acc Id: | ENSRNOP00000087078 ⟸ ENSRNOT00000097079 |
| RefSeq Acc Id: | NP_001406482 ⟸ NM_001419553 |
| - UniProtKB: | A0A0G2K7D4 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063131134 ⟸ XM_063275064 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063131136 ⟸ XM_063275066 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063131135 ⟸ XM_063275065 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A6KMJ8 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063131137 ⟸ XM_063275067 |
| - Peptide Label: | isoform X4 |
| - UniProtKB: | A0A0G2K7D4 (UniProtKB/TrEMBL) |
| Ensembl Acc Id: | ENSRNOP00000112549 ⟸ ENSRNOT00000154560 |
| Ensembl Acc Id: | ENSRNOP00000110882 ⟸ ENSRNOT00000150257 |
| Ensembl Acc Id: | ENSRNOP00000103541 ⟸ ENSRNOT00000160611 |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:619990 | AgrOrtholog |
| BioCyc Gene | G2FUF-12250 | BioCyc |
| Ensembl Genes | ENSRNOG00000059865 | Ensembl, ENTREZGENE |
| Ensembl Transcript | ENSRNOT00000079215 | ENTREZGENE |
| Gene3D-CATH | 1.10.287.2620 | UniProtKB/Swiss-Prot |
| 1.10.8.710 | UniProtKB/Swiss-Prot | |
| 1.10.8.720 | UniProtKB/Swiss-Prot | |
| 1.20.1270.280 | UniProtKB/Swiss-Prot | |
| 1.20.140.100 | UniProtKB/Swiss-Prot | |
| 1.20.58.1120 | UniProtKB/Swiss-Prot | |
| 1.20.920.30 | UniProtKB/Swiss-Prot | |
| 3.10.490.20 | UniProtKB/Swiss-Prot | |
| 3.20.180.20 | UniProtKB/Swiss-Prot | |
| 3.40.50.300 | UniProtKB/Swiss-Prot | |
| InterPro | AAA+_ATPase | UniProtKB/Swiss-Prot |
| AAA_6 | UniProtKB/Swiss-Prot | |
| AAA_lid_11 | UniProtKB/Swiss-Prot | |
| AAA_lid_11_sf | UniProtKB/Swiss-Prot | |
| DHC_fam | UniProtKB/Swiss-Prot | |
| DNAH3_AAA_lid_1 | UniProtKB/Swiss-Prot | |
| Dynein_2_C | UniProtKB/Swiss-Prot | |
| Dynein_2_N | UniProtKB/Swiss-Prot | |
| Dynein_AAA1S | UniProtKB/Swiss-Prot | |
| Dynein_AAA5_ext | UniProtKB/Swiss-Prot | |
| Dynein_C | UniProtKB/Swiss-Prot | |
| Dynein_C_barrel | UniProtKB/Swiss-Prot | |
| Dynein_heavy_chain_D4_dom | UniProtKB/Swiss-Prot | |
| Dynein_heavy_D6_P-loop | UniProtKB/Swiss-Prot | |
| Dynein_heavy_dom-2 | UniProtKB/Swiss-Prot | |
| P-loop_NTPase | UniProtKB/Swiss-Prot | |
| NCBI Gene | Dnah12 | ENTREZGENE |
| PANTHER | DYNEIN HEAVY CHAIN 2, AXONEMAL | UniProtKB/Swiss-Prot |
| DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED | UniProtKB/Swiss-Prot | |
| Pfam | AAA_6 | UniProtKB/Swiss-Prot |
| AAA_7 | UniProtKB/Swiss-Prot | |
| AAA_8 | UniProtKB/Swiss-Prot | |
| AAA_lid_1 | UniProtKB/Swiss-Prot | |
| AAA_lid_11 | UniProtKB/Swiss-Prot | |
| DHC_N2 | UniProtKB/Swiss-Prot | |
| Dynein_AAA_lid | UniProtKB/Swiss-Prot | |
| Dynein_C | UniProtKB/Swiss-Prot | |
| Dynein_heavy | UniProtKB/Swiss-Prot | |
| PhenoGen | Dnah12 | PhenoGen |
| RatGTEx | ENSRNOG00000059865 | RatGTEx |
| SMART | AAA | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot |
| UniProt | A0A0G2K7D4 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A8I6A750_RAT | UniProtKB/TrEMBL | |
| A0ABK0LFX1_RAT | UniProtKB/TrEMBL | |
| A0ABK0LNE0_RAT | UniProtKB/TrEMBL | |
| A0ABK0LWT2_RAT | UniProtKB/TrEMBL | |
| A6KMJ8 | ENTREZGENE, UniProtKB/TrEMBL | |
| DYH12_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2010-04-20 | Dnah12 | dynein, axonemal, heavy chain 12 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2009-01-20 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Bm259 | BM259 protein | Data merged from RGD:620941 | 737654 | APPROVED |
| 2005-01-20 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
| 2002-08-07 | Bm259 | BM259 protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
| 2002-08-07 | Dnah12 | dynein, axonemal, heavy polypeptide 12 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
| Note Type | Note | Reference |
|---|---|---|
| gene_disease | gene expression is upregulated in stroke-resistant spontaneously hypertensive (SHR) rats | 631971 |
| gene_expression | specifically expressed in trachea, testis, and brain | 632533 |