Sfmbt1 (Scm-like with four mbt domains 1) - Rat Genome Database

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Pathways
Gene: Sfmbt1 (Scm-like with four mbt domains 1) Rattus norvegicus
Analyze
Symbol: Sfmbt1
Name: Scm-like with four mbt domains 1
RGD ID: 61999
Description: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of muscle organ development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human SFMBT1 (Scm like with four mbt domains 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC680626; MGC93349; scm-like with four MBT domains protein 1; Scm-related gene containing four mbt domains; Sfmbt; similar to farnesyl diphosphate synthetase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,896,686 - 6,016,311 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl165,897,187 - 6,011,934 (+)EnsemblGRCr8
mRatBN7.2165,889,046 - 6,009,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,890,782 - 6,006,605 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx165,903,220 - 6,017,256 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,048,672 - 7,162,718 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,901,842 - 6,023,496 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0166,775,648 - 6,896,155 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)Ensemblrn6Rnor6.0
Rnor_5.0166,705,856 - 6,825,699 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4166,124,155 - 6,241,008 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera169,184,923 - 9,236,952 (-)NCBICelera
RGSC_v3.1166,185,489 - 6,241,002 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
folic acid  (ISO)
indometacin  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
8. Cloning of a novel murine gene Sfmbt, Scm-related gene containing four mbt domains, structurally belonging to the Polycomb group of genes. Usui H, etal., Gene 2000 May 2;248(1-2):127-35.
Additional References at PubMed
PMID:15489334   PMID:16751776   PMID:17599839   PMID:23349461   PMID:23592795  


Genomics

Comparative Map Data
Sfmbt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,896,686 - 6,016,311 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl165,897,187 - 6,011,934 (+)EnsemblGRCr8
mRatBN7.2165,889,046 - 6,009,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,890,782 - 6,006,605 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx165,903,220 - 6,017,256 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,048,672 - 7,162,718 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,901,842 - 6,023,496 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0166,775,648 - 6,896,155 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)Ensemblrn6Rnor6.0
Rnor_5.0166,705,856 - 6,825,699 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4166,124,155 - 6,241,008 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera169,184,923 - 9,236,952 (-)NCBICelera
RGSC_v3.1166,185,489 - 6,241,002 (+)NCBI
Cytogenetic Map16p16NCBI
SFMBT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,903,572 - 53,046,073 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,903,564 - 53,046,750 (-)Ensemblhg38GRCh38
GRCh37352,937,588 - 53,080,089 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,913,667 - 53,055,110 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34352,913,667 - 53,055,110NCBI
Celera352,916,400 - 53,047,177 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,999,200 - 53,129,628 (-)NCBIHuRef
CHM1_1352,889,772 - 53,031,734 (-)NCBICHM1_1
T2T-CHM13v2.0352,936,457 - 53,078,977 (-)NCBIT2T-CHM13v2.0
Sfmbt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,436,806 - 30,544,678 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,436,806 - 30,544,678 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381430,714,849 - 30,822,721 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,714,849 - 30,822,721 (+)Ensemblmm10GRCm38
MGSCv371431,528,035 - 31,635,907 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361429,595,009 - 29,646,972 (+)NCBIMGSCv36mm8
Celera1426,972,255 - 27,079,725 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.99NCBI
Sfmbt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,856,054 - 2,915,517 (-)Ensembl
ChiLan1.0NW_0049554302,850,149 - 3,014,859 (-)NCBIChiLan1.0ChiLan1.0
SFMBT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,899,440 - 53,045,144 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,904,212 - 53,049,915 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,841,693 - 52,991,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1354,071,144 - 54,215,061 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,071,144 - 54,138,538 (-)EnsemblpanPan2panpan1.1
SFMBT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,853,108 - 36,978,306 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,921,566 - 36,972,675 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2036,788,231 - 36,914,516 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02037,130,153 - 37,256,719 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,183,169 - 37,251,023 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,567,757 - 36,687,554 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02036,928,798 - 37,055,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,207,224 - 37,327,384 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sfmbt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,511,523 - 170,644,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,654,555 - 3,781,577 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,650,096 - 3,784,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFMBT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,025,769 - 35,180,042 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11335,020,627 - 35,181,074 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,213,183 - 38,314,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFMBT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,285,362 - 14,439,624 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2214,290,494 - 14,438,192 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041152,456,991 - 152,611,732 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sfmbt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,160,661 - 4,328,058 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sfmbt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1136,438,075 - 6,519,399 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sfmbt1
541 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:323
Count of miRNA genes:202
Interacting mature miRNAs:236
Transcripts:ENSRNOT00000022865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16423421216278352Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16423421216278352Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421216061395Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
631524Bp75Blood pressure QTL 750.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)161177108157035Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
RH130554  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,005,103 - 6,005,286 (+)MAPPERmRatBN7.2
Rnor_6.0166,894,924 - 6,895,106NCBIRnor6.0
Rnor_5.0166,820,954 - 6,821,136UniSTSRnor5.0
RGSC_v3.4166,240,631 - 6,240,813UniSTSRGSC3.4
Celera169,185,118 - 9,185,300UniSTS
RH 3.4 Map1634.2UniSTS
Cytogenetic Map16p16UniSTS
AW531515  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,889,119 - 5,889,285 (+)MAPPERmRatBN7.2
Rnor_6.0166,776,782 - 6,776,947NCBIRnor6.0
Rnor_5.0166,706,990 - 6,707,155UniSTSRnor5.0
RGSC_v3.4166,121,964 - 6,122,129UniSTSRGSC3.4
Celera169,299,445 - 9,299,610UniSTS
RH 3.4 Map1641.7UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 91 59 6 355 191 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001436894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008771006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB032164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC121615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ627111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000022865   ⟹   ENSRNOP00000022865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl165,897,187 - 6,011,934 (+)Ensembl
mRatBN7.2 Ensembl165,890,782 - 6,006,605 (+)Ensembl
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084713   ⟹   ENSRNOP00000074701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl165,897,187 - 6,011,440 (+)Ensembl
mRatBN7.2 Ensembl165,890,782 - 6,004,989 (+)Ensembl
Rnor_6.0 Ensembl166,806,170 - 6,895,007 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105144   ⟹   ENSRNOP00000082833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl165,962,444 - 6,011,934 (+)Ensembl
mRatBN7.2 Ensembl165,955,991 - 6,006,605 (+)Ensembl
RefSeq Acc Id: NM_031647   ⟹   NP_113835
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,980 - 6,011,932 (+)NCBI
mRatBN7.2165,891,524 - 6,005,481 (+)NCBI
Rnor_6.0166,779,281 - 6,895,301 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
RGSC_v3.4166,124,155 - 6,241,008 (+)RGD
Celera169,184,923 - 9,236,952 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252658   ⟹   XP_006252720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,896,686 - 6,016,311 (+)NCBI
mRatBN7.2165,889,046 - 6,009,860 (+)NCBI
Rnor_6.0166,775,648 - 6,896,155 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771006   ⟹   XP_008769228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,276 - 6,016,311 (+)NCBI
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094800   ⟹   XP_038950728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,794 - 6,016,311 (+)NCBI
mRatBN7.2165,891,213 - 6,009,860 (+)NCBI
RefSeq Acc Id: XM_039094801   ⟹   XP_038950729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,276 - 6,016,311 (+)NCBI
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
RefSeq Acc Id: XM_039094802   ⟹   XP_038950730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,794 - 6,016,311 (+)NCBI
mRatBN7.2165,891,213 - 6,009,860 (+)NCBI
RefSeq Acc Id: XM_063275675   ⟹   XP_063131745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,794 - 6,016,311 (+)NCBI
RefSeq Acc Id: XM_063275676   ⟹   XP_063131746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,276 - 6,016,311 (+)NCBI
RefSeq Acc Id: XM_063275677   ⟹   XP_063131747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,277 - 6,016,311 (+)NCBI
RefSeq Acc Id: XM_063275678   ⟹   XP_063131748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,794 - 6,016,311 (+)NCBI
RefSeq Acc Id: XM_063275680   ⟹   XP_063131750
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,897,278 - 6,016,311 (+)NCBI
RefSeq Acc Id: XM_063275681   ⟹   XP_063131751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,923,912 - 6,016,311 (+)NCBI
RefSeq Acc Id: NP_113835   ⟸   NM_031647
- UniProtKB: Q66HN3 (UniProtKB/Swiss-Prot),   Q9JMD2 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252720   ⟸   XM_006252658
- Peptide Label: isoform X1
- UniProtKB: Q66HN3 (UniProtKB/Swiss-Prot),   Q9JMD2 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769228   ⟸   XM_008771006
- Peptide Label: isoform X1
- UniProtKB: Q66HN3 (UniProtKB/Swiss-Prot),   Q9JMD2 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074701   ⟸   ENSRNOT00000084713
Ensembl Acc Id: ENSRNOP00000022865   ⟸   ENSRNOT00000022865
RefSeq Acc Id: XP_038950728   ⟸   XM_039094800
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950730   ⟸   XM_039094802
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950729   ⟸   XM_039094801
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082833   ⟸   ENSRNOT00000105144
RefSeq Acc Id: XP_063131746   ⟸   XM_063275676
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131747   ⟸   XM_063275677
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131750   ⟸   XM_063275680
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131748   ⟸   XM_063275678
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131745   ⟸   XM_063275675
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131751   ⟸   XM_063275681
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot),   Q66HN3 (UniProtKB/Swiss-Prot),   A6KG26 (UniProtKB/TrEMBL),   A0A8I5ZVZ3 (UniProtKB/TrEMBL)
Protein Domains
SAM   SLED

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JMD2-F1-model_v2 AlphaFold Q9JMD2 1-863 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699911
Promoter ID:EPDNEW_R10435
Type:initiation region
Name:Sfmbt1_1
Description:Scm-like with four mbt domains 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,779,262 - 6,779,322EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61999 AgrOrtholog
BioCyc Gene G2FUF-12183 BioCyc
Ensembl Genes ENSRNOG00000016645 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022865 ENTREZGENE
  ENSRNOT00000022865.6 UniProtKB/Swiss-Prot
  ENSRNOT00000105144 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.30.30.140 UniProtKB/Swiss-Prot
  3.90.1150.190 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7132495 IMAGE-MGC_LOAD
InterPro Mbt UniProtKB/Swiss-Prot
  MBT_SFMBT1_rpt2 UniProtKB/Swiss-Prot
  MBT_SFMBT1_rpt3 UniProtKB/Swiss-Prot
  PcG_chromatin_remod_factors UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Scm-like-4MBT1/2_SAM UniProtKB/Swiss-Prot
  SLED UniProtKB/Swiss-Prot
  SLED_sf UniProtKB/Swiss-Prot
KEGG Report rno:58967 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93349 IMAGE-MGC_LOAD
NCBI Gene 58967 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/Swiss-Prot
  SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1 UniProtKB/Swiss-Prot
Pfam MBT UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
  SLED UniProtKB/Swiss-Prot
PhenoGen Sfmbt1 PhenoGen
PROSITE MBT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016645 RatGTEx
SMART MBT UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  Tudor/PWWP/MBT UniProtKB/Swiss-Prot
TIGR TC219843
UniProt A0A8I5ZVZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UR87_RAT UniProtKB/TrEMBL
  A6KG26 ENTREZGENE, UniProtKB/TrEMBL
  Q66HN3 ENTREZGENE
  Q9JMD2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q66HN3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Sfmbt1  Scm-like with four mbt domains 1  LOC680626  similar to farnesyl diphosphate synthetase  Data merged from RGD:1589450 737654 PROVISIONAL
2006-11-19 LOC680626  similar to farnesyl diphosphate synthetase      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Sfmbt1  Scm-like with four mbt domains 1  Sfmbt  Scm-related gene containing four mbt domains   Symbol and Name updated 1299863 APPROVED
2002-06-10 Sfmbt  Scm-related gene containing four mbt domains       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains the SPM domain and mbt repeats 61748