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Gene: Itfg1 (integrin alpha FG-GAP repeat containing 1) Rattus norvegicus

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Symbol:

Itfg1

Name:

integrin alpha FG-GAP repeat containing 1

RGD ID:

619898

Description:

Predicted to be located in extracellular region and membrane. Predicted to be active in plasma membrane. Orthologous to human ITFG1 (integrin alpha FG-GAP repeat containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Cda08; CDA08-like protein; hypothetical protein CDA08; integrin-alpha FG-GAP repeat-containing protein 1; linkin; LOC103694297; MGC93216; T-cell immunomodulatory protein; uncharacterized LOC103694297

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Itfg1 (integrin alpha FG-GAP repeat containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ITFG1 (integrin alpha FG-GAP repeat containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	itfg1 (integrin alpha FG-GAP repeat containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lnkn-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7739	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	itfg1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	itfg1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	37,383,982 - 37,504,523 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	37,383,922 - 37,504,517 (+)	Ensembl				GRCr8
mRatBN7.2	19	21,210,697 - 21,331,285 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	21,210,733 - 21,331,279 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	22,893,548 - 23,013,694 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	28,088,070 - 28,208,221 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	31,050,875 - 31,171,013 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	22,281,906 - 22,403,548 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	22,281,906 - 22,403,542 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	33,289,326 - 33,410,847 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	22,561,637 - 22,682,885 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	21,075,489 - 21,195,835 (+)	NCBI		Celera
RGSC_v3.1	19	22,547,513 - 22,687,705 (+)	NCBI
Cytogenetic Map	19	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

dimethyl sulfoxide (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

ivermectin (ISO)

lead(0) (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nitrates (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

picoxystrobin (ISO)

potassium chromate (ISO)

propiconazole (ISO)

pyrogallol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

theophylline (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

extracellular region (IEA)

membrane (IEA)

plasma membrane (IBA,IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:23533145

Genomics

Comparative Map Data

Itfg1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	37,383,982 - 37,504,523 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	37,383,922 - 37,504,517 (+)	Ensembl				GRCr8
mRatBN7.2	19	21,210,697 - 21,331,285 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	21,210,733 - 21,331,279 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	22,893,548 - 23,013,694 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	28,088,070 - 28,208,221 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	31,050,875 - 31,171,013 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	22,281,906 - 22,403,548 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	22,281,906 - 22,403,542 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	33,289,326 - 33,410,847 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	22,561,637 - 22,682,885 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	21,075,489 - 21,195,835 (+)	NCBI		Celera
RGSC_v3.1	19	22,547,513 - 22,687,705 (+)	NCBI
Cytogenetic Map	19	p11	NCBI

ITFG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	47,154,391 - 47,461,246 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	47,154,387 - 47,464,149 (-)	Ensembl			hg38	GRCh38
GRCh37	16	47,188,302 - 47,495,157 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	45,746,798 - 46,052,519 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	16	45,746,800 - 46,052,516	NCBI
Celera	16	31,697,397 - 32,002,959 (-)	NCBI		Celera
Cytogenetic Map	16	q12.1	NCBI
HuRef	16	33,078,995 - 33,385,580 (-)	NCBI		HuRef
CHM1_1	16	48,596,276 - 48,902,048 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	52,951,220 - 53,258,064 (-)	NCBI		T2T-CHM13v2.0

Itfg1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	86,444,186 - 86,567,578 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	86,444,207 - 86,567,550 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	85,717,557 - 85,840,949 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	85,717,578 - 85,840,921 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	88,241,456 - 88,364,848 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	88,608,645 - 88,730,877 (-)	NCBI		MGSCv36	mm8
Celera	8	90,013,580 - 90,138,207 (-)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI
cM Map	8	41.61	NCBI

Itfg1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	7,801,203 - 8,020,961 (+)	Ensembl
ChiLan1.0	NW_004955474	7,800,984 - 8,020,891 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITFG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	56,611,915 - 56,914,293 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	62,515,848 - 62,819,104 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	27,416,955 - 27,720,197 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	46,305,573 - 46,611,710 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	46,305,573 - 46,613,463 (-)	Ensembl			panPan2	panpan1.1

ITFG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	67,475,847 - 67,767,674 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	67,476,650 - 67,766,475 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	64,051,187 - 64,342,814 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	68,033,832 - 68,325,598 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	68,034,718 - 68,325,595 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	64,847,097 - 65,138,117 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	65,870,369 - 66,161,938 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	67,009,404 - 67,153,010 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0
UU_Cfam_GSD_1.0	2	66,759,872 - 66,934,582 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Itfg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	58,809,938 - 59,070,813 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	518,237 - 779,214 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	518,262 - 779,215 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITFG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	37,193,711 - 37,432,883 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	37,193,632 - 37,430,910 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	32,411,274 - 32,673,834 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ITFG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	33,003,454 - 33,288,295 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	33,002,463 - 33,288,338 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	43,259,076 - 43,563,482 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itfg1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624914	720,601 - 1,013,739 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624914	721,206 - 1,013,734 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Itfg1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	17	13,191,388 - 13,263,308 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Itfg1
797 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	450
Count of miRNA genes:	227
Interacting mature miRNAs:	269
Transcripts:	ENSRNOT00000021711
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	7997750	52997750	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	19220689	64220689	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	7997750	52997750	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	5748064	50748064	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
2303628	Vencon9	Ventilatory control QTL 9		0.005	respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	19	23188586	68188586	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	31287532	51431640	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	7997750	52997750	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	7997750	52997750	Rat
1554318	Bmd5	Bone mineral density QTL 5	12.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	19	23188586	68188586	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	20109306	65109306	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat
61407	Scl12	Serum cholesterol level QTL 12		0.001	blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	19	30099383	47207961	Rat

Markers in Region

RH137139

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	21,330,999 - 21,331,209 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	22,403,263 - 22,403,472	NCBI	Rnor6.0
Rnor_5.0	19	33,410,562 - 33,410,771	UniSTS	Rnor5.0
RGSC_v3.4	19	22,682,600 - 22,682,809	UniSTS	RGSC3.4
Celera	19	21,195,550 - 21,195,759	UniSTS
Cytogenetic Map	19	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF480856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021711 ⟹ ENSRNOP00000021711

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	37,383,922 - 37,504,517 (+)	Ensembl
mRatBN7.2 Ensembl	19	21,210,733 - 21,331,279 (+)	Ensembl
Rnor_6.0 Ensembl	19	22,281,906 - 22,403,542 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149609 ⟹ ENSRNOP00000108747

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	37,383,932 - 37,504,517 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154365 ⟹ ENSRNOP00000110383

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	37,384,101 - 37,504,517 (+)	Ensembl

RefSeq Acc Id:

NM_133557 ⟹ NP_598241

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	37,383,982 - 37,504,523 (+)	NCBI
mRatBN7.2	19	21,210,733 - 21,331,285 (+)	NCBI
Rnor_6.0	19	22,281,906 - 22,403,548 (+)	NCBI
Rnor_5.0	19	33,289,326 - 33,410,847 (+)	NCBI
RGSC_v3.4	19	22,561,637 - 22,682,885 (+)	RGD
Celera	19	21,075,489 - 21,195,835 (+)	RGD

Sequence:

show sequence

GAGAAACAGCCCCAGGGCAGCGTGAGAATACAACGAGGGGCTGCCCGTAAGCTCGCACCCCGAG
TCTTTTCTCGGTCGGCCGGTTGCACGGTGCTTTGCGGCTGCCGTCAAGCGCGGCGGAGGCCGGC
CGGGCCGAAGGCGCCATGGCGGCAGGCCTGCTGCCTAGCGCCAGGGCGGTGCTGGCGCTGCTGT
TCTTGGGACTCGCGCTGCTGAGCGTTGGGCCTGCTCCGGCACAGGCTCTACACAATGTCACGGC
CGAGCTCTTTGGGGGTGAGGCCTGGGGCACCCTGGCGGCCTTCGGTGACCTCAACTCCGACAAA
CAGACGGACCTCTTCGTGCTGCGGGAAAGAAATGACTTAATCGTCTTTTTGGCAGATCAGAGTG
CACCCTATTTTAAACCCAAGGTAAAGGTGTCCTTGAAGAATTTCAGTGCATTGGTAACAAGTGT
AGTCCCTGGTGATTATGATGGGGACTCACAAATGGATGTCCTGCTCACATATTTTCCCCAAAAT
CATAGCAACAATGAATTAGGAGCTGTTATCTTCTGGGGACAAAATCAAACATTAGATCCTAAAA
ACATGACCATACTCAATAGGACTTTTCATGACCAGCCACTGATTATGGACTTCAACGGTGATCT
AATTCCTGATGTGTTTGCTATCACAAATGAATCCAGCCAGCCGCAGATACTGTTAGGAGGAGAT
TTGTCATGGCATCCTGCCTTGACCACTAAGAGTAAAATGCGGGACCCACATTCTCATGCATTTA
TTGATCTGACTGAAGATTTTACAGCAGATTTATTCCTTACAACATTGTCTGCCTCTAATACCTT
CCAGTTTGAGATATGGGAAAATTTGGGTGGAAACTTCTCTATCCGTAGTGTCTTTGAAAAACCT
AAAAATCTGGTGGTGGTTGGACAGTCAGCATTCGCAGACTTTGATGGAGATGGACACATGGATC
ACTTGCTGCCAGGCTGTGAAGATAAGGACTGTCAGAAAAGTGCCATTTATTTAATGAGATCAGG
AACAGGACAGTGGGCTCCTGTGCTTCAGGATTTTAGCAATAAGGGCACACTCTGGGGCTTTGTC
CCATTCGTGCATGAAGAGCGGCCAACTGCAATTCCAGTTCCACTCACACTTCACATTGGAGACT
ACAACATGGACGGCTACCCTGATGCTCTGGCCATATTAAAGAATACATCTGGAAGCAATCAGCA
AGCCTTCTTACTGGAGAATGTCCCGTGCAATAATGCGAGCTGTGAGGAAGTGCACCGGATGTTC
AAAGTCTACTGGGACCTAGCAGGCCTGAATCTAATCAAAGACGCCATGGTTGCCACCTTTTTTG
ACATTTATGAAGATGGGATCTTGGACATTATAGTCCTCAGTAAAGGATACACCAAGAGTGATGT
TGCCATCCACACACTCAAAAATAACTTTGAAGCAGATGCGTATTTTGTTAAAGTCATTGTTCTT
AGTGGTCTATGTTCTAGTGACTGTCCTCGTAAGATAACACCCTTTGGAGTGAATCAGCCTGGAC
CTTATATCATGTACACAACAGTAGATGCAAATGGGTATCTGAAAAATGGCTCAGCTGGGCAGCT
TAGCCAGTCAGCACACTTAGCTCTCCAGCTGCCTTACAATGTGCTTGGTTTAGGCCGAAGTGCC
AATTTCCTGGACCATCTTTTTGTTGGCATTCCCCGTCCATCTGGAGAGAAGTCTATAAGGAAAC
AAGAGTGGACAGCAATCATTCCAAATTCGCAGCTGATTGTCATCCCATACCCTCACAGTGTCCC
GAGAAGCTGGAGTGCCAAGTTGTACCTGACACCAAGTAACATTGTCCTGCTGACTGCGGTAGCC
CTCACCGGCGTCTGCGTCTTCATCCTGGCAATAATCGCCATTTTACACTGGCAGGAAAAGAAAG
CTGACGACAGGGAAAAGCGGCAAGAAGCACATCGCTTCCACTTTGACGCTATGTGATTCTGCTT
TCAGTGGTACATCCTGGAAGTCACTTGATTAGCGAAACACTAAACTTTGACTCCTAGTAAAAAA
AATAATGGATCTGAGATATTTATAAATTATGCCTTCCTTGTCAATTATTGGAAAATACTGAAAT
AAATATGGCCTGCATATCTCATAAGGTCTGCTTTAAGCACTCTGTATATAATAACCTAGCTTCT
TTATTCAGTGGTACTGAGCATTCTGTTCCTCTGTGGAATGTGTTGCATGTGCTCTGGTATTTGT
GTTTACAATGTTGTTAGAATTACGATGGTGGAAGGACATGTAAATAAAAACTATTTAAACAACC
TGGGGCCAGGACATTGTTCCACCTAAATTGATCTTGCTTTTTATCTTAAAAATGCACACTTTCT
CAACTATGTGGCAGATAAAGTTATTCAACTAACATTCTTCACTGCAGGGCAGAGCTCTGAGTGG
CATGGAATGAGACTAATTAGCCAGGCTTTGGAATCTCAGTAGGACAGACTGCCTTAGATGCCTG
GTTCTACAGCTTACAACTCTCTGAATCTGGCTACTGCTTAGCCTCTCTGTAAGCCGCAGTCTTG
TTTATATGATGTGGCTTATATGCCTGTTCACTTGAGTTATCGTGGATGTATACTGACTGATGCA
CACAGTGATCACTTGAGTTATCATGGATGTACACTGTCTGATGCACATGTGATCACTTGAGTTA
TCATGAATGTACATTGTTATATGATGCACATGTGTTCACTTGAGTTATCATGGATGTACATTGT
CTGATGCACATGGTGTACTTAGCTCAGTGCCTGAGCAAACAGGAAGTGTTCACCAAGCGGAGGC
TGTCCTTGCTCTTGCCGGTGATTTAATCTACTACTGTATAGAATGGATCATTATTATAGACATA
AGGACATACTCTTTGGAAAGCTTAAATTATTGGTGGTACATATCTCATATAATTAATTTGTTTG
ACTAGCTATATAATACTACCCAAGAGTAAATGTATCCTAAAACCTGGTACTTGAATACTGATCC
TTGTACAGTGATGTAAATCATTTGGTCTCTTGAAAGAAAGCTGACAGAGGCAAACTCTGGGGGT
GCAAACTGCCGTCACAGCTCTGCTCGCAGGACGGGAAAGTCAGTCTCAGTTCTCTTCAGACCAC
AGGGTTCATACTATGAACTTTACATTGCCAAAATTCACTTTAAAATTATTTAAATTAGAGTTGA
GGAGAGAGGTGATATTCAGATTACTAAGACATGCTGTGGCTGTAAACTATAAAAATTCCTCTAG
AACAGTTTTGTCTGTGTTATTTTCCCCACTGCAGTTCACTGAAGGGCATGTGCTCCTTTTTATT
TCTATTTAAGCATGTTAATGTATCGTCTTAATAAATACTCCTTACTGATTGAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_598241	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85706	(Get FASTA)	NCBI Sequence Viewer
	AAL84891	(Get FASTA)	NCBI Sequence Viewer
	EDL87495	(Get FASTA)	NCBI Sequence Viewer
	EDL87497	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021711
GenBank Protein	Q8R4E1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_598241 ⟸ NM_133557
- Peptide Label:	precursor
- UniProtKB:	Q8R4E1 (UniProtKB/Swiss-Prot), Q5U355 (UniProtKB/TrEMBL), A6KDC8 (UniProtKB/TrEMBL), F7FNV8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAGLLPSARAVLALLFLGLALLSVGPAPAQALHNVTAELFGGEAWGTLAAFGDLNSDKQTDLF VLRERNDLIVFLADQSAPYFKPKVKVSLKNFSALVTSVVPGDYDGDSQMDVLLTYFPQNHSNNE LGAVIFWGQNQTLDPKNMTILNRTFHDQPLIMDFNGDLIPDVFAITNESSQPQILLGGDLSWHP ALTTKSKMRDPHSHAFIDLTEDFTADLFLTTLSASNTFQFEIWENLGGNFSIRSVFEKPKNLVV VGQSAFADFDGDGHMDHLLPGCEDKDCQKSAIYLMRSGTGQWAPVLQDFSNKGTLWGFVPFVHE ERPTAIPVPLTLHIGDYNMDGYPDALAILKNTSGSNQQAFLLENVPCNNASCEEVHRMFKVYWD LAGLNLIKDAMVATFFDIYEDGILDIIVLSKGYTKSDVAIHTLKNNFEADAYFVKVIVLSGLCS SDCPRKITPFGVNQPGPYIMYTTVDANGYLKNGSAGQLSQSAHLALQLPYNVLGLGRSANFLDH LFVGIPRPSGEKSIRKQEWTAIIPNSQLIVIPYPHSVPRSWSAKLYLTPSNIVLLTAVALTGVC VFILAIIAILHWQEKKADDREKRQEAHRFHFDAM hide sequence

Ensembl Acc Id:

ENSRNOP00000021711 ⟸ ENSRNOT00000021711

Ensembl Acc Id:

ENSRNOP00000108747 ⟸ ENSRNOT00000149609

Ensembl Acc Id:

ENSRNOP00000110383 ⟸ ENSRNOT00000154365

Protein Domains

T-cell immunomodulatory protein TIP C2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R4E1-F1-model_v2	AlphaFold	Q8R4E1	1-610	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700989

Promoter ID:

EPDNEW_R11512

Type:

initiation region

Name:

Itfg1_1

Description:

integrin alpha FG-GAP repeat containing 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	22,281,870 - 22,281,930	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619898	AgrOrtholog
BioCyc Gene	G2FUF-6216	BioCyc
Ensembl Genes	ENSRNOG00000015843	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000021711	ENTREZGENE
Gene3D-CATH	2.130.10.130	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7189102	IMAGE-MGC_LOAD
InterPro	FG-GAP	UniProtKB/Swiss-Prot
	Integrin_alpha_N	UniProtKB/Swiss-Prot
	Tip	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93216	IMAGE-MGC_LOAD
NCBI Gene	171083	ENTREZGENE
PANTHER	PTHR13412	UniProtKB/Swiss-Prot
	T-CELL IMMUNOMODULATORY PROTEIN	UniProtKB/Swiss-Prot
Pfam	C2_ITFG1	UniProtKB/Swiss-Prot
	VCBS	UniProtKB/Swiss-Prot
PhenoGen	Itfg1	PhenoGen
RatGTEx	ENSRNOG00000015843	RatGTEx
Superfamily-SCOP	SSF69318	UniProtKB/Swiss-Prot
UniProt	A0ABK0LUV7_RAT	UniProtKB/TrEMBL
	A0ABK0M5J4_RAT	UniProtKB/TrEMBL
	A6KDC8	ENTREZGENE, UniProtKB/TrEMBL
	F7FNV8	ENTREZGENE, UniProtKB/TrEMBL
	Q5U355	ENTREZGENE
	Q8R4E1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Itfg1	integrin alpha FG-GAP repeat containing 1	LOC103694297	uncharacterized LOC103694297	Data merged from RGD:9399103	737654	PROVISIONAL
2014-08-25	LOC103694297	uncharacterized LOC103694297			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-02-19	Itfg1	integrin alpha FG-GAP repeat containing 1	Cda08	T-cell immunomodulatory protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Cda08	T-cell immunomodulatory protein		hypothetical protein CDA08	Name updated	1299863	APPROVED
2002-08-07	Cda08	hypothetical protein CDA08			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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