Fez2 (fasciculation and elongation protein zeta 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Fez2 (fasciculation and elongation protein zeta 2) Rattus norvegicus
Analyze
Symbol: Fez2
Name: fasciculation and elongation protein zeta 2
RGD ID: 619709
Description: Predicted to be involved in negative regulation of autophagosome assembly. Predicted to be active in axon and cytoplasm. Orthologous to human FEZ2 (fasciculation and elongation protein zeta 2); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fasciculation and elongation protein zeta 2 (zygin II); fasciculation and elongation protein zeta-2; MGC112579; synaptotagmin interacting protein zyginII; Zrp; zygin II; zygin-2; zygin-related protein; zygin-related protein types I/II
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,406,685 - 22,446,745 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl622,406,632 - 22,447,041 (+)EnsemblGRCr8
mRatBN7.2616,654,572 - 16,694,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,654,614 - 16,694,626 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx616,963,214 - 17,002,425 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,285,419 - 17,324,634 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,769,136 - 16,808,168 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)Ensemblrn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera616,298,245 - 16,337,422 (+)NCBICelera
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
chlordecone  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethylbenzene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
manganese(II) chloride  (EXP)
methimazole  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
nickel sulfate  (ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IBA)
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. mRNA expression of membrane-fusion-related proteins in rat parotid gland. Imai A, etal., Arch Oral Biol 2001 Oct;46(10):955-62.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14697253   PMID:25495476  


Genomics

Comparative Map Data
Fez2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,406,685 - 22,446,745 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl622,406,632 - 22,447,041 (+)EnsemblGRCr8
mRatBN7.2616,654,572 - 16,694,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,654,614 - 16,694,626 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx616,963,214 - 17,002,425 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,285,419 - 17,324,634 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,769,136 - 16,808,168 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)Ensemblrn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera616,298,245 - 16,337,422 (+)NCBICelera
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Cytogenetic Map6q12NCBI
FEZ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38236,552,258 - 36,598,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl236,531,805 - 36,646,087 (-)Ensemblhg38GRCh38
GRCh37236,779,401 - 36,825,311 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36236,632,905 - 36,678,836 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34236,691,056 - 36,736,886NCBI
Celera236,620,493 - 36,666,401 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef236,519,688 - 36,565,600 (-)NCBIHuRef
CHM1_1236,708,760 - 36,754,691 (-)NCBICHM1_1
T2T-CHM13v2.0236,556,883 - 36,604,833 (-)NCBIT2T-CHM13v2.0
Fez2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,676,641 - 78,725,581 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1778,676,641 - 78,725,581 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381778,369,212 - 78,418,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,369,212 - 78,418,152 (-)Ensemblmm10GRCm38
MGSCv371778,777,225 - 78,817,443 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361778,282,943 - 78,323,161 (-)NCBIMGSCv36mm8
Celera1782,679,824 - 82,720,044 (-)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.57NCBI
Fez2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554414,425,089 - 4,483,662 (-)Ensembl
ChiLan1.0NW_0049554414,421,936 - 4,456,070 (-)NCBIChiLan1.0ChiLan1.0
FEZ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,879,167 - 89,925,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,883,152 - 89,929,788 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A36,581,436 - 36,628,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A37,344,067 - 37,390,521 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,344,973 - 37,390,525 (-)EnsemblpanPan2panpan1.1
FEZ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,043,449 - 29,086,104 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,044,355 - 29,086,100 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1728,857,192 - 28,899,869 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01729,693,351 - 29,736,034 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1729,693,351 - 29,736,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11728,914,863 - 28,957,685 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01728,982,684 - 29,025,379 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,201,941 - 29,244,683 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fez2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,910,819 - 42,956,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366631,576,269 - 1,623,296 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366631,576,311 - 1,637,363 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEZ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,566,228 - 103,615,769 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13103,566,214 - 103,612,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23110,211,643 - 110,257,184 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FEZ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,822,793 - 70,899,025 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,822,885 - 70,865,129 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604541,062,030 - 41,136,419 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fez2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,216,715 - 18,260,729 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473818,217,238 - 18,260,096 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fez2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1714,802,412 - 14,842,263 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fez2
191 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:54
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000042735
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)62228825727729050Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)62228825732981219Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat

Markers in Region
D6Rat179  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,672,665 - 16,672,914 (-)MAPPERmRatBN7.2
Rnor_6.06985,684 - 985,932NCBIRnor6.0
Rnor_5.06977,509 - 977,757UniSTSRnor5.0
RGSC_v3.461,166,225 - 1,166,473UniSTSRGSC3.4
Celera616,316,207 - 16,316,455UniSTS
RGSC_v3.161,165,971 - 1,166,643RGD
FHH x ACI Map618.28UniSTS
FHH x ACI Map618.28RGD
Cytogenetic Map6q11UniSTS
RH134470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,694,407 - 16,694,608 (-)MAPPERmRatBN7.2
Rnor_6.06963,924 - 964,124NCBIRnor6.0
Rnor_5.06955,749 - 955,949UniSTSRnor5.0
RGSC_v3.461,144,535 - 1,144,735UniSTSRGSC3.4
Celera616,337,948 - 16,338,148UniSTS
Cytogenetic Map6q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001414905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_592821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB076183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB080086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK359698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U64689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042735   ⟹   ENSRNOP00000049923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,406,774 - 22,444,421 (+)Ensembl
mRatBN7.2 Ensembl616,654,614 - 16,693,882 (+)Ensembl
Rnor_6.0 Ensembl6964,551 - 1,004,001 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082071   ⟹   ENSRNOP00000075253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,406,632 - 22,446,745 (+)Ensembl
mRatBN7.2 Ensembl616,654,682 - 16,694,626 (+)Ensembl
Rnor_6.0 Ensembl6963,907 - 1,003,905 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101140   ⟹   ENSRNOP00000085973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,406,778 - 22,444,601 (+)Ensembl
mRatBN7.2 Ensembl616,654,682 - 16,692,482 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118155   ⟹   ENSRNOP00000089263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl622,406,774 - 22,447,041 (+)Ensembl
mRatBN7.2 Ensembl616,654,614 - 16,692,045 (+)Ensembl
RefSeq Acc Id: NM_001414905   ⟹   NP_001401834
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,797 - 22,446,745 (+)NCBI
mRatBN7.2616,654,702 - 16,694,626 (+)NCBI
RefSeq Acc Id: NM_053600   ⟹   NP_446052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,797 - 22,446,745 (+)NCBI
mRatBN7.2616,654,702 - 16,694,626 (+)NCBI
Rnor_6.06964,650 - 1,003,924 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
RGSC_v3.461,145,261 - 1,184,406 (-)RGD
Celera616,298,245 - 16,337,422 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239639   ⟹   XP_006239701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,698 - 22,435,733 (+)NCBI
mRatBN7.2616,654,601 - 16,674,060 (+)NCBI
Rnor_6.06983,462 - 1,003,955 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262567   ⟹   XP_063118637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,685 - 22,446,745 (+)NCBI
RefSeq Acc Id: XR_010052153
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,696 - 22,440,613 (+)NCBI
RefSeq Acc Id: NP_446052   ⟸   NM_053600
- Peptide Label: isoform 1
- UniProtKB: Q9JJ36 (UniProtKB/Swiss-Prot),   Q9JJ35 (UniProtKB/Swiss-Prot),   Q76LN1 (UniProtKB/Swiss-Prot),   P97578 (UniProtKB/Swiss-Prot),   A6H9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239701   ⟸   XM_006239639
- Peptide Label: isoform X1
- UniProtKB: F7EYQ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075253   ⟸   ENSRNOT00000082071
Ensembl Acc Id: ENSRNOP00000049923   ⟸   ENSRNOT00000042735
Ensembl Acc Id: ENSRNOP00000089263   ⟸   ENSRNOT00000118155
Ensembl Acc Id: ENSRNOP00000085973   ⟸   ENSRNOT00000101140
RefSeq Acc Id: NP_001401834   ⟸   NM_001414905
- Peptide Label: isoform 2
- UniProtKB: Q498V3 (UniProtKB/TrEMBL),   Q76LH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118637   ⟸   XM_063262567
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97578-F1-model_v2 AlphaFold P97578 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694359
Promoter ID:EPDNEW_R4875
Type:multiple initiation site
Name:Fez2_1
Description:fasciculation and elongation protein zeta 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,003,913 - 1,003,973EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619709 AgrOrtholog
BioCyc Gene G2FUF-38483 BioCyc
Ensembl Genes ENSRNOG00000004577 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000082071 ENTREZGENE
IMAGE_CLONE IMAGE:7128839 IMAGE-MGC_LOAD
InterPro FEZ UniProtKB/Swiss-Prot
KEGG Report rno:94269 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112579 IMAGE-MGC_LOAD
NCBI Gene 94269 ENTREZGENE
PANTHER PTHR12394 UniProtKB/Swiss-Prot
  PTHR12394:SF11 UniProtKB/Swiss-Prot
Pfam FEZ UniProtKB/Swiss-Prot
PhenoGen Fez2 PhenoGen
RatGTEx ENSRNOG00000004577 RatGTEx
UniProt A0A0G2KA44_RAT UniProtKB/TrEMBL
  A0A8I6A3L1_RAT UniProtKB/TrEMBL
  A0A8I6A8A8_RAT UniProtKB/TrEMBL
  A6H9W3_RAT UniProtKB/TrEMBL
  A6H9W4 ENTREZGENE, UniProtKB/TrEMBL
  A6H9W5_RAT UniProtKB/TrEMBL
  F7EYQ2 ENTREZGENE, UniProtKB/TrEMBL
  FEZ2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q498V3 ENTREZGENE, UniProtKB/TrEMBL
  Q76LH9 ENTREZGENE, UniProtKB/TrEMBL
  Q76LN1 ENTREZGENE
  Q9JJ35 ENTREZGENE
  Q9JJ36 ENTREZGENE
UniProt Secondary Q76LN1 UniProtKB/Swiss-Prot
  Q9JJ35 UniProtKB/Swiss-Prot
  Q9JJ36 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Fez2  fasciculation and elongation protein zeta 2  Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Zrp  zygin-related protein  Data merged from RGD:628711 737654 PROVISIONAL
2004-02-26 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Zrp  zygin-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to provisional 70820 PROVISIONAL