Psma3 (proteasome 20S subunit alpha 3) - Rat Genome Database

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Pathways
Gene: Psma3 (proteasome 20S subunit alpha 3) Rattus norvegicus
Analyze
Symbol: Psma3
Name: proteasome 20S subunit alpha 3
RGD ID: 61844
Description: Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of proteasome core complex, alpha-subunit complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human PSMA3 (proteasome 20S subunit alpha 3); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1,3-dinitrobenzene; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-7; macropain subunit C8; multicatalytic endopeptidase complex subunit C8; multicatalytic proteinase subunit K; proteasome (prosome, macropain) subunit, alpha type 3; proteasome component C8; proteasome subunit alpha 3; proteasome subunit alpha type 3-like; proteasome subunit alpha type-3; proteasome subunit alpha-7; proteasome subunit C8; proteasome subunit K; Psma3l
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,219,714 - 95,239,745 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl695,219,629 - 95,241,032 (+)EnsemblGRCr8
mRatBN7.2689,483,741 - 89,503,775 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,483,727 - 89,504,965 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx689,868,034 - 89,888,332 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,167,503 - 90,187,803 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,606,993 - 89,627,292 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,423,029 - 93,444,223 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)Ensemblrn6Rnor6.0
Rnor_5.06102,868,534 - 102,898,751 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4693,092,191 - 93,112,167 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera687,965,854 - 87,985,832 (+)NCBICelera
RGSC_v3.1693,095,646 - 93,115,622 (+)NCBI
Cytogenetic Map6q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,5-hexanedione  (EXP)
2,6-dimethoxyphenol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
ampicillin  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (EXP)
bufalin  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
cyclosporin A  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP)
dichlorine  (EXP)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
eugenol  (EXP)
finasteride  (EXP)
fluoxetine  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
metronidazole  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP)
monoethyl phthalate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nefazodone  (EXP)
neomycin  (EXP)
nickel atom  (ISO)
nickel subsulfide  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
Pentoxifylline  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
picrotoxin  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quinoline  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
vancomycin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Bingol B and Schuman EM, Nature. 2006 Jun 29;441(7097):1144-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. A genomic analysis of rat proteases and protease inhibitors. Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. An abundance of free regulatory (19S) proteasome particles regulates neuronal synapses. Sun C, etal., Science. 2023 May 26;380(6647):eadf2018. doi: 10.1126/science.adf2018. Epub 2023 May 26.
13. cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells. Tanaka K, etal., Biochem Biophys Res Commun 1990 Sep 14;171(2):676-83.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2249692   PMID:2335242   PMID:9688553   PMID:15489334   PMID:16207813   PMID:16641100   PMID:16857966   PMID:17323924   PMID:19056867   PMID:19208651   PMID:20458337   PMID:20498273  
PMID:21630459   PMID:22793692   PMID:23376485   PMID:25002582   PMID:26524591   PMID:30361391   PMID:31904090  


Genomics

Comparative Map Data
Psma3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,219,714 - 95,239,745 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl695,219,629 - 95,241,032 (+)EnsemblGRCr8
mRatBN7.2689,483,741 - 89,503,775 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,483,727 - 89,504,965 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx689,868,034 - 89,888,332 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,167,503 - 90,187,803 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,606,993 - 89,627,292 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,423,029 - 93,444,223 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)Ensemblrn6Rnor6.0
Rnor_5.06102,868,534 - 102,898,751 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4693,092,191 - 93,112,167 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera687,965,854 - 87,985,832 (+)NCBICelera
RGSC_v3.1693,095,646 - 93,115,622 (+)NCBI
Cytogenetic Map6q24NCBI
PSMA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381458,244,843 - 58,272,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1458,244,740 - 58,272,012 (+)Ensemblhg38GRCh38
GRCh371458,711,561 - 58,738,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361457,781,346 - 57,808,479 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341457,781,345 - 57,808,479NCBI
Celera1438,761,540 - 38,788,685 (+)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1438,877,058 - 38,904,216 (+)NCBIHuRef
CHM1_11458,650,049 - 58,677,295 (+)NCBICHM1_1
T2T-CHM13v2.01452,451,770 - 52,478,987 (+)NCBIT2T-CHM13v2.0
Psma3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391271,016,082 - 71,042,651 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1271,021,395 - 71,043,121 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381270,969,283 - 70,995,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,974,621 - 70,996,347 (+)Ensemblmm10GRCm38
MGSCv371272,075,610 - 72,095,924 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361271,893,298 - 71,913,526 (+)NCBIMGSCv36mm8
Celera1272,078,082 - 72,098,500 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.39NCBI
Psma3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546611,979,482 - 11,997,952 (+)Ensembl
ChiLan1.0NW_00495546611,979,482 - 11,997,952 (+)NCBIChiLan1.0ChiLan1.0
PSMA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21559,364,546 - 59,394,007 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11458,583,210 - 58,610,522 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01438,836,869 - 38,864,152 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11457,105,891 - 57,133,181 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1457,105,891 - 57,133,181 (+)EnsemblpanPan2panpan1.1
PSMA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1833,616,735 - 33,642,434 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl833,616,480 - 33,642,404 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha833,378,219 - 33,403,729 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0833,858,343 - 33,884,028 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl833,858,385 - 33,884,037 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1833,471,278 - 33,496,743 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0833,538,435 - 33,564,256 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0833,913,572 - 33,939,074 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Psma3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864071,519,504 - 71,541,053 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364952,650,629 - 2,673,435 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364952,650,668 - 2,672,192 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1187,343,507 - 187,372,193 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11187,342,231 - 187,371,149 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21208,246,764 - 208,274,223 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12435,438,084 - 35,465,320 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2435,437,308 - 35,465,203 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605323,674,689 - 23,701,992 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psma3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248843,324,418 - 3,346,128 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248843,324,390 - 3,346,128 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Psma3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1784,633,037 - 84,653,290 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Psma3
134 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:102
Interacting mature miRNAs:124
Transcripts:ENSRNOT00000010753
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat

Markers in Region
RH127444  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,503,492 - 89,503,708 (+)MAPPERmRatBN7.2
Rnor_6.0693,442,743 - 93,442,958NCBIRnor6.0
Rnor_5.06102,898,469 - 102,898,684UniSTSRnor5.0
RGSC_v3.4693,111,885 - 93,112,100UniSTSRGSC3.4
Celera687,985,550 - 87,985,765UniSTS
RH 3.4 Map6639.3UniSTS
Cytogenetic Map6q24UniSTS
RH138090  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8695,221,416 - 95,221,563 (+)Marker Load Pipeline
mRatBN7.2689,485,444 - 89,485,591 (+)MAPPERmRatBN7.2
Rnor_6.0693,424,697 - 93,424,843NCBIRnor6.0
Rnor_5.06102,870,438 - 102,870,584UniSTSRnor5.0
RGSC_v3.4693,093,859 - 93,094,005UniSTSRGSC3.4
Celera687,967,522 - 87,967,668UniSTS
RH 3.4 Map6640.3UniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map6q24UniSTS
RH130667  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,504,584 - 89,504,785 (+)MAPPERmRatBN7.2
Rnor_6.0693,443,835 - 93,444,035NCBIRnor6.0
Rnor_5.06102,899,561 - 102,899,761UniSTSRnor5.0
RGSC_v3.4693,112,977 - 93,113,177UniSTSRGSC3.4
Celera687,986,642 - 87,986,842UniSTS
RH 3.4 Map6639.5UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010753   ⟹   ENSRNOP00000010753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl695,220,656 - 95,237,161 (+)Ensembl
mRatBN7.2 Ensembl689,484,684 - 89,501,189 (+)Ensembl
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl693,437,383 - 93,441,873 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105733   ⟹   ENSRNOP00000084525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl695,219,687 - 95,241,032 (+)Ensembl
mRatBN7.2 Ensembl689,483,740 - 89,504,965 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114457   ⟹   ENSRNOP00000094706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl695,219,629 - 95,238,843 (+)Ensembl
mRatBN7.2 Ensembl689,483,727 - 89,503,086 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119219   ⟹   ENSRNOP00000096724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,484,684 - 89,501,189 (+)Ensembl
RefSeq Acc Id: NM_017280   ⟹   NP_058976
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,219,749 - 95,239,745 (+)NCBI
mRatBN7.2689,483,777 - 89,503,775 (+)NCBI
Rnor_6.0693,423,029 - 93,443,025 (+)NCBI
Rnor_5.06102,868,534 - 102,898,751 (+)NCBI
RGSC_v3.4693,092,191 - 93,112,167 (+)RGD
Celera687,965,854 - 87,985,832 (+)RGD
Sequence:
RefSeq Acc Id: XM_017594059   ⟹   XP_017449548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,219,714 - 95,238,653 (+)NCBI
mRatBN7.2689,483,741 - 89,502,746 (+)NCBI
Rnor_6.0693,424,370 - 93,444,223 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063261592   ⟹   XP_063117662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,220,008 - 95,238,653 (+)NCBI
RefSeq Acc Id: XM_063261593   ⟹   XP_063117663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,219,900 - 95,238,653 (+)NCBI
RefSeq Acc Id: NP_058976   ⟸   NM_017280
- UniProtKB: P18422 (UniProtKB/Swiss-Prot),   A6HC06 (UniProtKB/TrEMBL),   Q6IE67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449548   ⟸   XM_017594059
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000010753   ⟸   ENSRNOT00000010753
Ensembl Acc Id: ENSRNOP00000084525   ⟸   ENSRNOT00000105733
Ensembl Acc Id: ENSRNOP00000094706   ⟸   ENSRNOT00000114457
Ensembl Acc Id: ENSRNOP00000096724   ⟸   ENSRNOT00000119219
RefSeq Acc Id: XP_063117663   ⟸   XM_063261593
- Peptide Label: isoform X3
- UniProtKB: A6HH67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117662   ⟸   XM_063261592
- Peptide Label: isoform X1
- UniProtKB: Q6IE67 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18422-F1-model_v2 AlphaFold P18422 1-255 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694647
Promoter ID:EPDNEW_R5170
Type:initiation region
Name:Psma3_1
Description:proteasome subunit alpha 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0693,422,967 - 93,423,027EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61844 AgrOrtholog
BioCyc Gene G2FUF-37187 BioCyc
Ensembl Genes ENSRNOG00000007851 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010753 ENTREZGENE
  ENSRNOT00000105733 ENTREZGENE
  ENSRNOT00000105733.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110009 IMAGE-MGC_LOAD
InterPro Ntn_hydrolases_N UniProtKB/Swiss-Prot
  Proteasome_alpha UniProtKB/Swiss-Prot
  Proteasome_alpha-type UniProtKB/Swiss-Prot
  Proteasome_asu_N UniProtKB/Swiss-Prot
  Proteasome_sua/b UniProtKB/Swiss-Prot
KEGG Report rno:29670 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93511 IMAGE-MGC_LOAD
NCBI Gene 29670 ENTREZGENE
PANTHER PROTEASOME SUBUNIT ALPHA/BETA UniProtKB/Swiss-Prot
Pfam Proteasome UniProtKB/Swiss-Prot
  Proteasome_A_N UniProtKB/Swiss-Prot
PhenoGen Psma3 PhenoGen
PROSITE PROTEASOME_ALPHA_1 UniProtKB/Swiss-Prot
  PROTEASOME_ALPHA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007851 RatGTEx
SMART Proteasome_A_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56235 UniProtKB/Swiss-Prot
TIGR TC216589
UniProt A0A8I6B1E1_RAT UniProtKB/TrEMBL
  A0A8L2Q4S0_RAT UniProtKB/TrEMBL
  A6HC06 ENTREZGENE, UniProtKB/TrEMBL
  A6HH67 ENTREZGENE, UniProtKB/TrEMBL
  P18422 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6IE67 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Psma3  proteasome 20S subunit alpha 3  Psma3  proteasome subunit alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-19 Psma3  proteasome subunit alpha 3  Psma3  proteasome (prosome, macropain) subunit, alpha type 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Psma3  proteasome (prosome, macropain) subunit, alpha type 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference