Syn3 (synapsin III) - Rat Genome Database

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Pathways
Gene: Syn3 (synapsin III) Rattus norvegicus
Analyze
Symbol: Syn3
Name: synapsin III
RGD ID: 3799
Description: Enables ATP binding activity. Predicted to be involved in synapse organization and synaptic vesicle clustering. Located in synaptic vesicle. Is extrinsic component of synaptic vesicle membrane. Orthologous to human SYN3 (synapsin III); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100910134; synapsin 3; synapsin-3; synapsin-3-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,244,032 - 19,701,571 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl719,264,094 - 19,696,510 (+)EnsemblGRCr8
mRatBN7.2716,216,055 - 17,808,790 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx719,338,160 - 19,770,881 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,496,950 - 21,928,082 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,277,828 - 21,710,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,403,896 - 23,808,602 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)Ensemblrn6Rnor6.0
Rnor_5.0723,553,831 - 23,958,150 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4719,544,439 - 19,940,847 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera714,630,545 - 15,035,838 (+)NCBICelera
RGSC_v3.1719,552,680 - 19,953,765 (+)NCBI
Cytogenetic Map7q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Synapsin III, a novel synapsin with an unusual regulation by Ca2+. Hosaka M and Sudhof TC, J Biol Chem 1998 May 29;273(22):13371-4.
5. Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Jaffrey SR, etal., Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3199-204. Epub 2002 Feb 26.
6. A third member of the synapsin gene family. Kao HT, etal., Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4667-72.
7. A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Lam PP, etal., Mol Biol Cell. 2007 Jul;18(7):2473-80. Epub 2007 Apr 18.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10358015   PMID:12040043   PMID:15071120   PMID:17114649   PMID:25843720  


Genomics

Comparative Map Data
Syn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,244,032 - 19,701,571 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl719,264,094 - 19,696,510 (+)EnsemblGRCr8
mRatBN7.2716,216,055 - 17,808,790 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx719,338,160 - 19,770,881 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,496,950 - 21,928,082 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,277,828 - 21,710,529 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,403,896 - 23,808,602 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)Ensemblrn6Rnor6.0
Rnor_5.0723,553,831 - 23,958,150 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4719,544,439 - 19,940,847 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera714,630,545 - 15,035,838 (+)NCBICelera
RGSC_v3.1719,552,680 - 19,953,765 (+)NCBI
Cytogenetic Map7q13NCBI
SYN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,507,820 - 33,058,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,507,820 - 33,058,381 (-)Ensemblhg38GRCh38
GRCh372232,903,807 - 33,454,367 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,238,540 - 31,732,683 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342231,233,093 - 31,727,237NCBI
Celera2216,710,711 - 17,256,522 (-)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2215,865,721 - 16,411,951 (-)NCBIHuRef
CHM1_12232,867,892 - 33,413,788 (-)NCBICHM1_1
T2T-CHM13v2.02232,971,715 - 33,522,831 (-)NCBIT2T-CHM13v2.0
Syn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,884,610 - 86,336,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1085,890,989 - 86,334,760 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381086,048,746 - 86,498,926 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,055,125 - 86,498,896 (-)Ensemblmm10GRCm38
MGSCv371085,511,491 - 85,961,641 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361085,485,308 - 85,928,638 (-)NCBIMGSCv36mm8
Celera1088,022,524 - 88,480,347 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.95NCBI
Syn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540541,455,465 - 41,762,920 (-)Ensembl
ChiLan1.0NW_00495540541,450,081 - 41,762,894 (-)NCBIChiLan1.0ChiLan1.0
SYN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22342,435,668 - 43,001,939 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12245,136,351 - 45,700,243 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02213,517,932 - 14,069,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12231,373,466 - 31,920,997 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2231,373,604 - 31,866,798 (-)EnsemblpanPan2panpan1.1
SYN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11030,475,134 - 30,927,758 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1030,482,870 - 30,923,257 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1030,458,198 - 30,910,923 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01031,316,595 - 31,770,135 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1031,316,551 - 31,767,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11031,058,009 - 31,509,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01031,347,117 - 31,799,406 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01031,531,822 - 31,985,721 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Syn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494513,825,984 - 14,243,677 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364926,876,684 - 7,253,375 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364926,836,441 - 7,253,867 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl512,473,793 - 12,500,076 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1512,017,741 - 12,501,995 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2512,196,607 - 12,291,334 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SYN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11915,330,179 - 15,821,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045110,129,396 - 110,678,492 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247501,699,107 - 1,972,252 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247501,663,309 - 1,976,738 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Syn3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11162,108,157 - 162,543,735 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Syn3
4429 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:322
Count of miRNA genes:199
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000037918
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
D7Mgh9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8719,510,666 - 19,510,815 (+)Marker Load Pipeline
Rnor_6.0723,645,249 - 23,645,397NCBIRnor6.0
Rnor_5.0723,795,488 - 23,795,636UniSTSRnor5.0
RGSC_v3.4719,778,187 - 19,778,336RGDRGSC3.4
RGSC_v3.4719,778,188 - 19,778,336UniSTSRGSC3.4
Celera714,861,467 - 14,861,602UniSTS
RGSC_v3.1719,788,447 - 19,788,596RGD
RH 2.0 Map779.3RGD
Cytogenetic Map7q13UniSTS
D7Rat40  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,777,285 - 17,777,527 (+)MAPPERmRatBN7.2
Rnor_6.0723,783,311 - 23,783,552NCBIRnor6.0
Rnor_5.0723,933,259 - 23,933,500UniSTSRnor5.0
RGSC_v3.4719,915,731 - 19,916,213RGDRGSC3.4
RGSC_v3.4719,915,925 - 19,916,166UniSTSRGSC3.4
Celera715,011,032 - 15,011,271UniSTS
RGSC_v3.1719,928,649 - 19,929,131RGD
RH 2.0 Map778.0RGD
SHRSP x BN Map76.87RGD
Cytogenetic Map7q13UniSTS
D7Rat216  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8719,566,070 - 19,566,284 (+)Marker Load Pipeline
mRatBN7.2717,678,338 - 17,678,552 (+)MAPPERmRatBN7.2
Rnor_6.0723,700,654 - 23,700,867NCBIRnor6.0
Rnor_5.0723,850,893 - 23,851,106UniSTSRnor5.0
RGSC_v3.4719,833,592 - 19,833,806RGDRGSC3.4
RGSC_v3.4719,833,593 - 19,833,806UniSTSRGSC3.4
Celera714,916,655 - 14,916,868UniSTS
RGSC_v3.1719,847,222 - 19,847,649RGD
SHRSP x BN Map76.87UniSTS
SHRSP x BN Map76.87RGD
Cytogenetic Map7q13UniSTS
RH128273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,310 - 17,523,527 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,609 - 23,545,825NCBIRnor6.0
Rnor_5.0723,695,848 - 23,696,064UniSTSRnor5.0
RGSC_v3.4719,678,548 - 19,678,764UniSTSRGSC3.4
Celera714,762,644 - 14,762,860UniSTS
Cytogenetic Map7q13UniSTS
RH129267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,345 - 17,523,536 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,644 - 23,545,834NCBIRnor6.0
Rnor_5.0723,695,883 - 23,696,073UniSTSRnor5.0
RGSC_v3.4719,678,583 - 19,678,773UniSTSRGSC3.4
Celera714,762,679 - 14,762,869UniSTS
Cytogenetic Map7q13UniSTS
RH94615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,524,335 - 17,524,409 (+)MAPPERmRatBN7.2
Rnor_6.0723,546,634 - 23,546,707NCBIRnor6.0
Rnor_5.0723,696,873 - 23,696,946UniSTSRnor5.0
RGSC_v3.4719,679,573 - 19,679,646UniSTSRGSC3.4
Celera714,763,669 - 14,763,742UniSTS
Cytogenetic Map7q13UniSTS
RH143027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,679,415 - 17,679,605 (+)MAPPERmRatBN7.2
Rnor_6.0723,701,731 - 23,701,920NCBIRnor6.0
Rnor_5.0723,851,970 - 23,852,159UniSTSRnor5.0
RGSC_v3.4719,834,670 - 19,834,859UniSTSRGSC3.4
Celera714,917,732 - 14,917,921UniSTS
Cytogenetic Map7q13UniSTS
RH144261  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,551,976 - 17,552,083 (+)MAPPERmRatBN7.2
Rnor_6.0723,574,271 - 23,574,377NCBIRnor6.0
Rnor_5.0723,724,510 - 23,724,616UniSTSRnor5.0
RGSC_v3.4719,707,210 - 19,707,316UniSTSRGSC3.4
Celera714,791,244 - 14,791,350UniSTS
Cytogenetic Map7q13UniSTS
BI278238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,117 - 17,523,220 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,416 - 23,545,518NCBIRnor6.0
Rnor_5.0723,695,655 - 23,695,757UniSTSRnor5.0
RGSC_v3.4719,678,355 - 19,678,457UniSTSRGSC3.4
Celera714,762,451 - 14,762,553UniSTS
Cytogenetic Map7q13UniSTS
BF400160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,802,723 - 17,802,823 (+)MAPPERmRatBN7.2
Rnor_6.0723,808,746 - 23,808,845NCBIRnor6.0
Rnor_5.0723,958,294 - 23,958,393UniSTSRnor5.0
RGSC_v3.4719,940,991 - 19,941,090UniSTSRGSC3.4
Celera715,035,982 - 15,036,081UniSTS
Cytogenetic Map7q13UniSTS
RH135110  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,522,418 - 17,522,611 (+)MAPPERmRatBN7.2
Rnor_6.0723,544,717 - 23,544,909NCBIRnor6.0
Rnor_5.0723,694,956 - 23,695,148UniSTSRnor5.0
RGSC_v3.4719,677,656 - 19,677,848UniSTSRGSC3.4
Celera714,761,752 - 14,761,944UniSTS
Cytogenetic Map7q13UniSTS
RH141014  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8719,408,827 - 19,409,022 (+)Marker Load Pipeline
mRatBN7.2717,521,115 - 17,521,310 (+)MAPPERmRatBN7.2
Rnor_6.0723,543,414 - 23,543,608NCBIRnor6.0
Rnor_5.0723,693,653 - 23,693,847UniSTSRnor5.0
RGSC_v3.4719,676,353 - 19,676,547UniSTSRGSC3.4
Celera714,760,452 - 14,760,643UniSTS
Cytogenetic Map7q13UniSTS
Timp3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,945 - 17,524,436 (+)MAPPERmRatBN7.2
Rnor_6.0723,546,244 - 23,546,734NCBIRnor6.0
Rnor_5.0723,696,483 - 23,696,973UniSTSRnor5.0
RGSC_v3.4719,679,183 - 19,679,673UniSTSRGSC3.4
Celera714,763,279 - 14,763,769UniSTS
Cytogenetic Map7q13UniSTS
G45201  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,562,016 - 17,562,389 (+)MAPPERmRatBN7.2
mRatBN7.2717,562,046 - 17,562,389 (+)MAPPERmRatBN7.2
Rnor_6.0723,584,341 - 23,584,683NCBIRnor6.0
Rnor_6.0723,584,311 - 23,584,683NCBIRnor6.0
Rnor_5.0723,734,580 - 23,734,922UniSTSRnor5.0
Rnor_5.0723,734,550 - 23,734,922UniSTSRnor5.0
RGSC_v3.4719,717,250 - 19,717,622UniSTSRGSC3.4
RGSC_v3.4719,717,280 - 19,717,622UniSTSRGSC3.4
Celera714,801,206 - 14,801,548UniSTS
Celera714,801,176 - 14,801,548UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 13 95 259 91 90 59 217 59 6 580 364 30 226 129 155 31 51 51

Sequence


Ensembl Acc Id: ENSRNOT00000037918   ⟹   ENSRNOP00000036740
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl719,264,094 - 19,696,510 (+)Ensembl
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)Ensembl
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)Ensembl
RefSeq Acc Id: NM_017109   ⟹   NP_058805
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,264,086 - 19,696,510 (+)NCBI
mRatBN7.2717,376,364 - 17,808,790 (+)NCBI
Rnor_6.0723,403,896 - 23,808,602 (+)NCBI
Rnor_5.0723,553,831 - 23,958,150 (+)NCBI
RGSC_v3.4719,544,439 - 19,940,847 (+)RGD
Celera714,630,545 - 15,035,838 (+)RGD
Sequence:
RefSeq Acc Id: XM_063263102   ⟹   XP_063119172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,473 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263103   ⟹   XP_063119173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,244,032 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263104   ⟹   XP_063119174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,492 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263105   ⟹   XP_063119175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,484 - 19,701,571 (+)NCBI
RefSeq Acc Id: NP_058805   ⟸   NM_017109
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036740   ⟸   ENSRNOT00000037918
RefSeq Acc Id: XP_063119173   ⟸   XM_063263103
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119172   ⟸   XM_063263102
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119175   ⟸   XM_063263105
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119174   ⟸   XM_063263104
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70441-F1-model_v2 AlphaFold O70441 1-579 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3799 AgrOrtholog
BioCyc Gene G2FUF-34667 BioCyc
Ensembl Genes ENSRNOG00000026866 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037918 ENTREZGENE
  ENSRNOT00000037918.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1490.20 UniProtKB/Swiss-Prot
  3.40.50.20 UniProtKB/Swiss-Prot
  ATP-grasp fold, B domain UniProtKB/Swiss-Prot
InterPro ATP_grasp_subdomain_1 UniProtKB/Swiss-Prot
  PreATP-grasp_dom_sf UniProtKB/Swiss-Prot
  Synapsin UniProtKB/Swiss-Prot
  Synapsin_ATP-bd_dom UniProtKB/Swiss-Prot
  Synapsin_CS UniProtKB/Swiss-Prot
  Synapsin_P_site UniProtKB/Swiss-Prot
  Synapsin_pre-ATP-grasp_dom UniProtKB/Swiss-Prot
KEGG Report rno:29130 UniProtKB/Swiss-Prot
NCBI Gene 29130 ENTREZGENE
PANTHER SYNAPSIN UniProtKB/Swiss-Prot
  SYNAPSIN-3 UniProtKB/Swiss-Prot
Pfam Synapsin UniProtKB/Swiss-Prot
  Synapsin_C UniProtKB/Swiss-Prot
  Synapsin_N UniProtKB/Swiss-Prot
PhenoGen Syn3 PhenoGen
PRINTS SYNAPSIN UniProtKB/Swiss-Prot
PROSITE SYNAPSIN_1 UniProtKB/Swiss-Prot
  SYNAPSIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000026866 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot
  SSF52440 UniProtKB/Swiss-Prot
UniProt A0A096MIT7 ENTREZGENE, UniProtKB/TrEMBL
  A6IFC2 ENTREZGENE, UniProtKB/TrEMBL
  O70441 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Syn3  synapsin III  LOC100910134  synapsin-3-like  Data merged from RGD:6500248 737654 PROVISIONAL
2012-07-05 LOC100910134  synapsin-3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Syn3  synapsin III    synapsin 3  Name updated 1299863 APPROVED
2002-06-10 Syn3  synapsin 3      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function binds ATP with high affinity and ADP with a lower affinity 70029
gene_regulation ATP binding is inhibited by Ca2+ 70029