Stk10 (serine/threonine kinase 10) - Rat Genome Database

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Gene: Stk10 (serine/threonine kinase 10) Rattus norvegicus
Analyze
Symbol: Stk10
Name: serine/threonine kinase 10
RGD ID: 3779
Description: Predicted to enable protein homodimerization activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including lymphocyte aggregation; protein autophosphorylation; and regulation of lymphocyte migration. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human STK10 (serine/threonine kinase 10); INTERACTS WITH 1-benzylpiperazine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: serine/threonine-protein kinase 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,622,149 - 17,716,337 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1017,622,162 - 17,716,332 (+)EnsemblGRCr8
mRatBN7.21017,117,860 - 17,212,065 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,117,878 - 17,212,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1021,863,541 - 21,960,798 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,352,145 - 21,449,405 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,842,732 - 16,937,737 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,420,964 - 17,521,810 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,421,075 - 17,519,706 (+)Ensemblrn6Rnor6.0
Rnor_5.01017,316,575 - 17,409,682 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41017,379,245 - 17,481,768 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1016,764,695 - 16,858,924 (+)NCBICelera
RGSC_v3.11017,438,282 - 17,482,813 (+)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (EXP)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cobalt dichloride  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
disodium selenite  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methoxychlor  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
thioacetamide  (EXP)
thiophenes  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
plasma membrane  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The identification of a novel cDNA preferentially expressed in the olfactory-limbic system of the adult rat. Schaar DG, etal., Brain Res 1996 May 20;721(1-2):217-28.
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10692593   PMID:12639966   PMID:18239682   PMID:19255442   PMID:20458337   PMID:37721438  


Genomics

Comparative Map Data
Stk10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,622,149 - 17,716,337 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1017,622,162 - 17,716,332 (+)EnsemblGRCr8
mRatBN7.21017,117,860 - 17,212,065 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,117,878 - 17,212,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1021,863,541 - 21,960,798 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,352,145 - 21,449,405 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,842,732 - 16,937,737 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,420,964 - 17,521,810 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,421,075 - 17,519,706 (+)Ensemblrn6Rnor6.0
Rnor_5.01017,316,575 - 17,409,682 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41017,379,245 - 17,481,768 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1016,764,695 - 16,858,924 (+)NCBICelera
RGSC_v3.11017,438,282 - 17,482,813 (+)NCBI
Cytogenetic Map10q12NCBI
STK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385172,042,079 - 172,188,224 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5172,042,079 - 172,188,332 (-)Ensemblhg38GRCh38
GRCh375171,469,083 - 171,615,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,401,679 - 171,547,951 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345171,403,229 - 171,547,865NCBI
Celera5167,501,519 - 167,647,757 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,566,183 - 166,679,569 (-)NCBIHuRef
CHM1_15170,901,480 - 171,048,064 (-)NCBICHM1_1
T2T-CHM13v2.05172,582,378 - 172,728,531 (-)NCBIT2T-CHM13v2.0
Stk10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,483,266 - 32,574,595 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,483,305 - 32,574,587 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381132,533,266 - 32,624,595 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,533,305 - 32,624,587 (+)Ensemblmm10GRCm38
MGSCv371132,433,266 - 32,524,595 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361132,433,305 - 32,524,587 (+)NCBIMGSCv36mm8
Celera1134,952,605 - 35,043,796 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.97NCBI
Stk10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,862,365 - 24,977,713 (-)Ensembl
ChiLan1.0NW_00495540824,864,033 - 24,977,713 (-)NCBIChiLan1.0ChiLan1.0
STK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24167,184,526 - 167,327,758 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,324,071 - 165,467,219 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,396,133 - 167,539,286 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,311,171 - 174,455,082 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,311,171 - 174,455,082 (-)EnsemblpanPan2panpan1.1
STK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,087,558 - 40,199,934 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,086,698 - 40,198,029 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha440,036,481 - 40,148,888 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0440,463,149 - 40,575,387 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,463,067 - 40,575,385 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,278,578 - 40,390,727 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,468,463 - 40,580,898 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0440,978,687 - 41,091,100 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stk10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,370,867 - 94,481,111 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,093,554 - 3,203,792 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,093,597 - 3,203,786 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,003,887 - 52,140,367 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11652,003,768 - 52,140,378 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,726,108 - 56,743,092 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,196,033 - 74,343,450 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660344,279,131 - 4,430,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stk10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473317,829,773 - 17,949,532 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473317,829,802 - 17,955,643 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Stk10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v195,377,827 - 5,466,280 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Stk10
708 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:276
Count of miRNA genes:187
Interacting mature miRNAs:224
Transcripts:ENSRNOT00000047011
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101576223019737486Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
D10Got34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,210,462 - 17,210,616 (+)MAPPERmRatBN7.2
Rnor_6.01017,520,208 - 17,520,361NCBIRnor6.0
Rnor_5.01017,408,080 - 17,408,233UniSTSRnor5.0
RGSC_v3.41017,480,165 - 17,480,319RGDRGSC3.4
RGSC_v3.41017,480,166 - 17,480,319UniSTSRGSC3.4
Celera1016,857,322 - 16,857,475UniSTS
RGSC_v3.11017,481,214 - 17,481,368RGD
RH 2.0 Map10180.1RGD
Cytogenetic Map10q12.3UniSTS
D10Wox27  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,210,509 - 17,210,637 (+)MAPPERmRatBN7.2
Rnor_6.01017,520,255 - 17,520,382NCBIRnor6.0
Rnor_5.01017,408,127 - 17,408,254UniSTSRnor5.0
RGSC_v3.41017,480,212 - 17,480,340RGDRGSC3.4
RGSC_v3.41017,480,213 - 17,480,340UniSTSRGSC3.4
Celera1016,857,369 - 16,857,496UniSTS
RGSC_v3.11017,481,261 - 17,481,389RGD
Cytogenetic Map10q12.3UniSTS
AA997828  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,211,842 - 17,212,023 (+)MAPPERmRatBN7.2
Rnor_6.01017,521,588 - 17,521,768NCBIRnor6.0
Rnor_5.01017,409,460 - 17,409,640UniSTSRnor5.0
RGSC_v3.41017,481,546 - 17,481,726UniSTSRGSC3.4
Celera1016,858,702 - 16,858,882UniSTS
Cytogenetic Map10q12.3UniSTS
RH129287  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,211,795 - 17,211,980 (+)MAPPERmRatBN7.2
Rnor_6.01017,521,541 - 17,521,725NCBIRnor6.0
Rnor_5.01017,409,413 - 17,409,597UniSTSRnor5.0
RGSC_v3.41017,481,499 - 17,481,683UniSTSRGSC3.4
Celera1016,858,655 - 16,858,839UniSTS
Cytogenetic Map10q12.3UniSTS
AU049011  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,210,424 - 17,210,609 (+)MAPPERmRatBN7.2
Rnor_6.01017,520,170 - 17,520,354NCBIRnor6.0
Rnor_5.01017,408,042 - 17,408,226UniSTSRnor5.0
RGSC_v3.41017,480,128 - 17,480,312UniSTSRGSC3.4
Celera1016,857,284 - 16,857,468UniSTS
Cytogenetic Map10q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000047011   ⟹   ENSRNOP00000044325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,622,162 - 17,716,332 (+)Ensembl
mRatBN7.2 Ensembl1017,117,878 - 17,212,061 (+)Ensembl
Rnor_6.0 Ensembl1017,421,075 - 17,519,706 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080404   ⟹   ENSRNOP00000074413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,622,162 - 17,716,332 (+)Ensembl
mRatBN7.2 Ensembl1017,117,878 - 17,212,061 (+)Ensembl
Rnor_6.0 Ensembl1017,486,579 - 17,519,706 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162791   ⟹   ENSRNOP00000112678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1017,622,162 - 17,716,332 (+)Ensembl
RefSeq Acc Id: NM_019206   ⟹   NP_062079
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,622,164 - 17,716,337 (+)NCBI
mRatBN7.21017,117,880 - 17,212,065 (+)NCBI
Rnor_6.01017,420,969 - 17,521,810 (+)NCBI
Rnor_5.01017,316,575 - 17,409,682 (+)NCBI
RGSC_v3.41017,379,245 - 17,481,768 (+)RGD
Celera1016,764,695 - 16,858,924 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085736   ⟹   XP_038941664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,622,149 - 17,716,335 (+)NCBI
mRatBN7.21017,117,860 - 17,212,063 (+)NCBI
RefSeq Acc Id: XM_039085737   ⟹   XP_038941665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,665,809 - 17,716,335 (+)NCBI
mRatBN7.21017,161,529 - 17,212,063 (+)NCBI
RefSeq Acc Id: XM_063268809   ⟹   XP_063124879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,622,149 - 17,716,335 (+)NCBI
RefSeq Acc Id: NP_062079   ⟸   NM_019206
- UniProtKB: H9KVF6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074413   ⟸   ENSRNOT00000080404
Ensembl Acc Id: ENSRNOP00000044325   ⟸   ENSRNOT00000047011
RefSeq Acc Id: XP_038941664   ⟸   XM_039085736
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K7Z9 (UniProtKB/TrEMBL),   H9KVF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941665   ⟸   XM_039085737
- Peptide Label: isoform X3
- UniProtKB: H9KVF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124879   ⟸   XM_063268809
- Peptide Label: isoform X2
- UniProtKB: H9KVF6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112678   ⟸   ENSRNOT00000162791
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PTG8-F1-model_v2 AlphaFold E9PTG8 1-967 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697092
Promoter ID:EPDNEW_R7617
Type:multiple initiation site
Name:Stk10_1
Description:serine/threonine kinase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01017,420,998 - 17,421,058EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3779 AgrOrtholog
BioCyc Gene G2FUF-25624 BioCyc
Ensembl Genes ENSRNOG00000004217 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000047011 ENTREZGENE
  ENSRNOT00000080404 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  PKK UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  STE20_Ser/Thr_Kinases UniProtKB/Swiss-Prot
  STK10_STKc UniProtKB/Swiss-Prot
NCBI Gene 29398 ENTREZGENE
PANTHER PROTEIN KINASE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  SERINE/THREONINE-PROTEIN KINASE 10 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
  PKK UniProtKB/Swiss-Prot
PhenoGen Stk10 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004217 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
TIGR TC217910
UniProt A0A0G2K7Z9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M3N0_RAT UniProtKB/TrEMBL
  A6HDF4_RAT UniProtKB/TrEMBL
  A6HDF5_RAT UniProtKB/TrEMBL
  A6HDF7_RAT UniProtKB/TrEMBL
  E9PTG8 ENTREZGENE
  H9KVF6 ENTREZGENE, UniProtKB/TrEMBL
  STK10_RAT UniProtKB/Swiss-Prot
UniProt Secondary D3ZUC0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Stk10  Serine/threonine kinase 10      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains has potential coiled coil formation domains which encode a highly alpha-helical molecule 634157
gene_expression expressed in the olfactory-limbic system of the adult rat brain 634157
gene_process helps in the survival of substantia nigra (SN) dopaminergic neurons 634157